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The map label for this gene is deoR [H]

Identifier: 126697601

GI number: 126697601

Start: 57469

End: 58422

Strand: Direct

Name: deoR [H]

Synonym: CD0035

Alternate gene names: 126697601

Gene position: 57469-58422 (Clockwise)

Preceding gene: 126697600

Following gene: 126697602

Centisome position: 1.34

GC content: 28.83

Gene sequence:

>954_bases
ATGAAAAAAATTGGAGACTTAAGATTAATGATGAAGTGTTGTTCACTTTATTACGAAGATAATTTGAATCAACAGGAAAT
AGCAAATCAATTGGGAATATCAAGACCAACAATATCAAGAATATTAAAAGAAGCTTTTGAACAAGGAATAGTAAAAATAC
AGATAGTTGATGTTTTGAAAAATGATTACCAAAAAATAGAGAGAAGTTTGGAGAGAAAATATAAATTAAAAGAAGTAATA
GTAGTAGATGATAAACAGGATGCACTAACACAAAAACAAGAACTAGCAAGAGCTGTATCTGAATATTTAACTAGAGTAGT
AAAGGAAAATGATATAATAGGTGTTTCAATAGGAACAACACTAAAAGAAATACCAAGATATGTGGAAAAAAGTAACTGTA
AAAATGTTACATTTATACCTCTATTAGGAGGGATTGGAGACAATGAAATAGATATTCATGCAAATCAAATAGCAGTAAGT
TTAGCGAGGGCTTTTGGAGGTGATTTTAAATTATTACATGCTCCAGCTGTTATGTCTGACTTGTCTACAAAAGAGAAACT
TTGCAAAGACGAAAAAATTAAAGAAGTACTAGATTTAATAGATAAAACAACTATAGCAATTGTGGGTATAGGAAATCCTA
TGAGTTTAAACTCAACAATAATGGCTTCTGGATACATGAATGAAGCAGATATAGAAGATTTAAAAAAATACAACTCAATA
GGTGCAATTTGTTTACAAGCCTTTGATAAAGAAGGAAAAACTTCTATACTTGAATTTAATCAAAGAGTATTAGGAGTGAA
ACTGGAAGATTTAAAAAAGATAAAAAGAACAATAGGTGTCGCTTCAGGAGATGAAAAAATAGAGGCAATAAAGGCATCAT
TAAAAGCGAAATTTATAAATAGTTTAGCAATTAATCACAGTTTAGCACTTAAATTATTAGAAGATTGTGACTAA

Upstream 100 bases:

>100_bases
GACTTTTTATATGAACCCCTTCTATAATGTTACTGAAATTAAGTAAAATGATTGAACAAATGTAAAGATAATTGAAAAGC
TTGATTTTGGAGGAAAGCAA

Downstream 100 bases:

>100_bases
TAGAAAGATAGATAAAAGTTAACAGGAGGGAATGTATATGTCAATATCAAAAGAAACATTGCTTGAAATGTATAAGAGAA
TGAATCAGGCTAGAAAATTT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MKKIGDLRLMMKCCSLYYEDNLNQQEIANQLGISRPTISRILKEAFEQGIVKIQIVDVLKNDYQKIERSLERKYKLKEVI
VVDDKQDALTQKQELARAVSEYLTRVVKENDIIGVSIGTTLKEIPRYVEKSNCKNVTFIPLLGGIGDNEIDIHANQIAVS
LARAFGGDFKLLHAPAVMSDLSTKEKLCKDEKIKEVLDLIDKTTIAIVGIGNPMSLNSTIMASGYMNEADIEDLKKYNSI
GAICLQAFDKEGKTSILEFNQRVLGVKLEDLKKIKRTIGVASGDEKIEAIKASLKAKFINSLAINHSLALKLLEDCD

Sequences:

>Translated_317_residues
MKKIGDLRLMMKCCSLYYEDNLNQQEIANQLGISRPTISRILKEAFEQGIVKIQIVDVLKNDYQKIERSLERKYKLKEVI
VVDDKQDALTQKQELARAVSEYLTRVVKENDIIGVSIGTTLKEIPRYVEKSNCKNVTFIPLLGGIGDNEIDIHANQIAVS
LARAFGGDFKLLHAPAVMSDLSTKEKLCKDEKIKEVLDLIDKTTIAIVGIGNPMSLNSTIMASGYMNEADIEDLKKYNSI
GAICLQAFDKEGKTSILEFNQRVLGVKLEDLKKIKRTIGVASGDEKIEAIKASLKAKFINSLAINHSLALKLLEDCD
>Mature_317_residues
MKKIGDLRLMMKCCSLYYEDNLNQQEIANQLGISRPTISRILKEAFEQGIVKIQIVDVLKNDYQKIERSLERKYKLKEVI
VVDDKQDALTQKQELARAVSEYLTRVVKENDIIGVSIGTTLKEIPRYVEKSNCKNVTFIPLLGGIGDNEIDIHANQIAVS
LARAFGGDFKLLHAPAVMSDLSTKEKLCKDEKIKEVLDLIDKTTIAIVGIGNPMSLNSTIMASGYMNEADIEDLKKYNSI
GAICLQAFDKEGKTSILEFNQRVLGVKLEDLKKIKRTIGVASGDEKIEAIKASLKAKFINSLAINHSLALKLLEDCD

Specific function: Negative regulator of the dra-nupC-pdp operon. DeoR binds cooperatively to the operator DNA, which consists of a palindrome and a direct repeat sequence located 3' to the palindrome [H]

COG id: COG2390

COG function: function code K; Transcriptional regulator, contains sigma factor-related N-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sorC transcriptional regulatory family [H]

Homologues:

Organism=Escherichia coli, GI87082414, Length=312, Percent_Identity=29.1666666666667, Blast_Score=148, Evalue=6e-37,
Organism=Escherichia coli, GI1787791, Length=307, Percent_Identity=26.0586319218241, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR007630
- InterPro:   IPR007324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04545 Sigma70_r4; PF04198 Sugar-bind [H]

EC number: NA

Molecular weight: Translated: 35378; Mature: 35378

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIGDLRLMMKCCSLYYEDNLNQQEIANQLGISRPTISRILKEAFEQGIVKIQIVDVLK
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEHHHHHH
NDYQKIERSLERKYKLKEVIVVDDKQDALTQKQELARAVSEYLTRVVKENDIIGVSIGTT
HHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHH
LKEIPRYVEKSNCKNVTFIPLLGGIGDNEIDIHANQIAVSLARAFGGDFKLLHAPAVMSD
HHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEHHHHHHHHHHHHCCCEEEEECHHHHHH
LSTKEKLCKDEKIKEVLDLIDKTTIAIVGIGNPMSLNSTIMASGYMNEADIEDLKKYNSI
HHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEECCCCCCCCHHHHHHHHHH
GAICLQAFDKEGKTSILEFNQRVLGVKLEDLKKIKRTIGVASGDEKIEAIKASLKAKFIN
HHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
SLAINHSLALKLLEDCD
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKIGDLRLMMKCCSLYYEDNLNQQEIANQLGISRPTISRILKEAFEQGIVKIQIVDVLK
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEHHHHHH
NDYQKIERSLERKYKLKEVIVVDDKQDALTQKQELARAVSEYLTRVVKENDIIGVSIGTT
HHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHH
LKEIPRYVEKSNCKNVTFIPLLGGIGDNEIDIHANQIAVSLARAFGGDFKLLHAPAVMSD
HHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEHHHHHHHHHHHHCCCEEEEECHHHHHH
LSTKEKLCKDEKIKEVLDLIDKTTIAIVGIGNPMSLNSTIMASGYMNEADIEDLKKYNSI
HHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEECCCCCCCCHHHHHHHHHH
GAICLQAFDKEGKTSILEFNQRVLGVKLEDLKKIKRTIGVASGDEKIEAIKASLKAKFIN
HHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
SLAINHSLALKLLEDCD
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550462; 8867804; 9384377; 10074062; 10714997 [H]