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The map label for this gene is tadA [H]

Identifier: 126697581

GI number: 126697581

Start: 19544

End: 19999

Strand: Direct

Name: tadA [H]

Synonym: CD0015

Alternate gene names: 126697581

Gene position: 19544-19999 (Clockwise)

Preceding gene: 126697580

Following gene: 126697582

Centisome position: 0.46

GC content: 28.07

Gene sequence:

>456_bases
ATGGAAAGTTCATTTTATATGAAAGAAGCATTAAAAGAAGCATATAAAGCATATAATAAAAAAGAAACACCAATAGGTGC
TATTATAGTTAAAGATAATCAAATAATAGCTAGAGCTCATAACCTTACAGAAACGTTAAAAGACTCTACGGCACATGCAG
AAATTTTAGCGATAAAACAAGCATCAGAAAAATTAGGTGGTTGGAGGTTGACTGATTGTGATTTATATGTTACAATGGAA
CCTTGCATAATGTGTAGTGGTGCAATAGTTAATTCTAGAATAAAAAAGCTTATAATAGGGACAAGACATGTAAAAAATTC
ATATATAGAAAAACAGCATGAGTTTAAATTAGATTATTTTAATAATAATAATGTAAAAGTAGCTTTTGATGTTTTGCAAG
AAGAATGCTCGATCATATTGCAAGAATTTTTTAAGGCATTGAGAAAAAGAGATTAA

Upstream 100 bases:

>100_bases
TAGCTATATATAGTAATAATTAAATAAACAAAATAAAATTAAGTTGAATTATAAAATGAATTATGATAAGATAAGTTTGT
TATAAGTTTTGGGAGGAATT

Downstream 100 bases:

>100_bases
GGAGAGATGGTCGAGTGGTCGAAGGCGCTCGCCTGGAAAGCGAGTATATGGGTAAAACTGTATCGTGGGTTCAAATCCCA
CTCTCTCCGCCAGAAACAAT

Product: cytosine/adenosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MESSFYMKEALKEAYKAYNKKETPIGAIIVKDNQIIARAHNLTETLKDSTAHAEILAIKQASEKLGGWRLTDCDLYVTME
PCIMCSGAIVNSRIKKLIIGTRHVKNSYIEKQHEFKLDYFNNNNVKVAFDVLQEECSIILQEFFKALRKRD

Sequences:

>Translated_151_residues
MESSFYMKEALKEAYKAYNKKETPIGAIIVKDNQIIARAHNLTETLKDSTAHAEILAIKQASEKLGGWRLTDCDLYVTME
PCIMCSGAIVNSRIKKLIIGTRHVKNSYIEKQHEFKLDYFNNNNVKVAFDVLQEECSIILQEFFKALRKRD
>Mature_151_residues
MESSFYMKEALKEAYKAYNKKETPIGAIIVKDNQIIARAHNLTETLKDSTAHAEILAIKQASEKLGGWRLTDCDLYVTME
PCIMCSGAIVNSRIKKLIIGTRHVKNSYIEKQHEFKLDYFNNNNVKVAFDVLQEECSIILQEFFKALRKRD

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=108, Percent_Identity=32.4074074074074, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI145693172, Length=145, Percent_Identity=35.1724137931034, Blast_Score=120, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17554608, Length=112, Percent_Identity=38.3928571428571, Blast_Score=84, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17541138, Length=153, Percent_Identity=26.797385620915, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17555996, Length=98, Percent_Identity=35.7142857142857, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355527, Length=147, Percent_Identity=27.891156462585, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 17377; Mature: 17377

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESSFYMKEALKEAYKAYNKKETPIGAIIVKDNQIIARAHNLTETLKDSTAHAEILAIKQ
CCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCEEEHHHHHHHHHHHCCCCHHHHHHHHH
ASEKLGGWRLTDCDLYVTMEPCIMCSGAIVNSRIKKLIIGTRHVKNSYIEKQHEFKLDYF
HHHHHCCEEEECCEEEEEECHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEE
NNNNVKVAFDVLQEECSIILQEFFKALRKRD
CCCCEEEHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MESSFYMKEALKEAYKAYNKKETPIGAIIVKDNQIIARAHNLTETLKDSTAHAEILAIKQ
CCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCEEEHHHHHHHHHHHCCCCHHHHHHHHH
ASEKLGGWRLTDCDLYVTMEPCIMCSGAIVNSRIKKLIIGTRHVKNSYIEKQHEFKLDYF
HHHHHCCEEEECCEEEEEECHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEE
NNNNVKVAFDVLQEECSIILQEFFKALRKRD
CCCCEEEHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1698458; 7584024; 9384377 [H]