| Definition | Prochlorococcus marinus str. MIT 9301, complete genome. |
|---|---|
| Accession | NC_009091 |
| Length | 1,641,879 |
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The map label for this gene is acnB [H]
Identifier: 126697229
GI number: 126697229
Start: 1619439
End: 1622012
Strand: Direct
Name: acnB [H]
Synonym: P9301_18911
Alternate gene names: 126697229
Gene position: 1619439-1622012 (Clockwise)
Preceding gene: 126697227
Following gene: 126697230
Centisome position: 98.63
GC content: 33.76
Gene sequence:
>2574_bases ATGAAGAATATGGAAACATTGCTAAAAAATTATGCAGATCATGTAGCTGAAAGAGCTGCCAAAGGTATACCTCCTTTACC TTTAAATGCTGAACAAACAAATTGTATTACAAAATTATTAGAAAAAGATAGTACTTACGATTCATCTTATTTACTTGATT TACTAATAAATAGAGTACCCCCAGGAGTTGATGAAGCTGCTTACGTAAAAGCAAGCTGGCTTACGGCTATTGTTAATTCC GAAAAATATTGCAAATCGATTAATCCCGAAAAAGCAATTGAAATACTAGGAACAATGATAGGCGGATATAATGTAAATTC TTTGGTTGAAATACTTAAAGGAGAAAATAGTTTACTCGCAAAAAAAGCGGCAGAAGTTTTAAAAAATATTATTCTTGTGT ACGACTCGGCTAATGAAATTTATGAATTATCTCAAAATAATATTTATGCAAAAGAAATTGTAAATAGTTGGGCAAATGCA GAATGGTTCATAAATAAAAAAGTTCTGGAGAAAGAGATTACTTGTTTAGTATTTAAAGTTGACGGTGAGACAAACACAGA CGACTTATCTCCAGCTGTACATGCAACAACACGCCCAGATATTCCAATGCATGCATTAGCTATGTTGGAATTTAAAAAAC CTGATGGACTAAAGATTCTTAATAATTTAAAAAAACAAAATTTACCAATAGCTTATGTTGGAGATGTTGTTGGAACAGGG AGTTCTAGAAAATCTGCTATTAATTCACTCATTTGGCATATAGGAGAAGATATCGCTTTTGTTCCTAACAAAAAAACCGG TGGAATAATAATTGGCAGCAAAATAGCCCCAATTTTCTTCAATACTGCACAAGATTCAGGAGCTTTACCAATAGAAGCTG ACGTATCTCAAATGAAAACAGGAGATGTTATTAAAATATATCCCTATAAAGGCATTATTAAAAAAATTGAAAAAGAATCA AATACTGAAGAATTAATAAGCAAATTCGAGTTATATCCTTCAACTCTTACTGATGAAATTCAAGCTGGCGGAAGAATTAA TCTTATGATTGGAAGATCTCTTACGGACAAAATTAGAAACAAACTAGATTATCAACCAAGTGAAATATTTACTAGACCAC AAAATCCAACTGAAAGTAGTGCCGGATTTACCCAAGCTCAAAAAATAGTAGGCAAAGCATGCGGTTTAGATGGAGTTAGG CCAGGAATGACCTGTGAGCCAATTATGACCACAGTTGGTAGTCAAGATACTACTGGGCCAATGACTAGAGATGAATTAAA AGAACTAGCTTGTTTAGGATTTACTGCAGATTTAGTGATGCAAAGTTTTTGTCATACAGCTGCATATCCTAAACCAGTAG ATTTACTTACCCATAAAGAATTACCTGATTTTATATCTCAAAGAGGTGGAGTAGCTCTTAAACCTGGAGATGGCATCATT CATAGCTGGCTTAACAGAATGCTTCTCCCTGATACTGTTGGCACAGGTGGAGATAGTCATACAAGATTTCCTCTTGGCAT TTCATTTCCTGGAGGCTCTGGCATTGTTGCATTTGCCGCTGCAATAGGATCAATGCCATTAAATATGCCGGAATCTGTGC TGGTTAAATTTAAGGGAGAATTATTACCAGGAATTACTCTTAGAGATTTAGTTAATGCAATCCCTCTCTTCGCAATTAAA GAAGGGCTATTAACTGTTGAGAAAGAAAATAAGAAAAATATATTCAACGGGAAAATTATGGAAATTGAGGGATTACCAAA CCTAAAACTTGAACAAGCTTTTGAACTTACTGATGCTACTGCAGAACGCTCATGCGCTGGTAGCACAATACTTTTATCCC AAGAAACTGTTCAAGAATATTTAAAAAGCAATATTTGCCTGCTAGAAAAAATGGTCGAGAGCAATTATGAAGATTCAAAA TCGATTTCAAGAAGAATAAATGATATGAAAAATTGGTTAAAAAAACCATCATTAATTCAACCAGATTCAAACGCTCAGTA TGAAGAAATCATTGAAATTGATTTAGCAAAAGTAACACAACCTATAGTTGCTTGTCCTAATGATCCAGATAATGTAAAAG AAATCACTGATGTTGCAAATACAAATATTGACGAGGTTTTTATAGGTTCTTGTATGACAAATATTGGTCATTACAGGGCA GCTGCAAAAGTGCTTGAAGGAGTACAAAATTTAAAAGCTAAATTATGGATTTGTCCACCAACAAAGATGGATGAAGAAAC TCTAAAAGCTGAAGGCTACTATAAAATATTTGAAGATTGTGGAGCAAGATTAGAGTTGCCAGGCTGTTCTTTATGTATGG GAAATCAAGCTAGAGTTGAAGAAGGTTCTGTAGTATTTTCTACAAGTACAAGAAATTTTGACAATAGACTTGGCAAGAAT GCGCAAGTATTTTTAGGGAGTGCAGAATTGGCAGCAGTTTGTGCACTGCTTGGAAAAATACCTGAAATTGAAGAATATCA GGATATTACTAAAAATAAAATTAATCCATATTCAGATGAACTTTATCGCTATCTTCAATTTGATGAAATACACGATTTCA GCTTGACAAAGTAA
Upstream 100 bases:
>100_bases CATTGATTAATTAAGGAGTTTGAATATTTAAAAAAGCATTTATGAATACTCTCCTTTTCAATATTAAAAATAACAATAGA TTAGGCATTAAACCTTACTA
Downstream 100 bases:
>100_bases TCATGGACCATGCCAAACTTTATAAAAGATAATATTCAAAAAACAAGTAATAATTCTTCTCGTAGCATCAAAAAATTATT AAAACAAAGATCTCTAGTCG
Product: bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase
Products: NA
Alternate protein names: Aconitase 2; 2-methylisocitrate dehydratase; Citrate hydro-lyase 2 [H]
Number of amino acids: Translated: 857; Mature: 857
Protein sequence:
>857_residues MKNMETLLKNYADHVAERAAKGIPPLPLNAEQTNCITKLLEKDSTYDSSYLLDLLINRVPPGVDEAAYVKASWLTAIVNS EKYCKSINPEKAIEILGTMIGGYNVNSLVEILKGENSLLAKKAAEVLKNIILVYDSANEIYELSQNNIYAKEIVNSWANA EWFINKKVLEKEITCLVFKVDGETNTDDLSPAVHATTRPDIPMHALAMLEFKKPDGLKILNNLKKQNLPIAYVGDVVGTG SSRKSAINSLIWHIGEDIAFVPNKKTGGIIIGSKIAPIFFNTAQDSGALPIEADVSQMKTGDVIKIYPYKGIIKKIEKES NTEELISKFELYPSTLTDEIQAGGRINLMIGRSLTDKIRNKLDYQPSEIFTRPQNPTESSAGFTQAQKIVGKACGLDGVR PGMTCEPIMTTVGSQDTTGPMTRDELKELACLGFTADLVMQSFCHTAAYPKPVDLLTHKELPDFISQRGGVALKPGDGII HSWLNRMLLPDTVGTGGDSHTRFPLGISFPGGSGIVAFAAAIGSMPLNMPESVLVKFKGELLPGITLRDLVNAIPLFAIK EGLLTVEKENKKNIFNGKIMEIEGLPNLKLEQAFELTDATAERSCAGSTILLSQETVQEYLKSNICLLEKMVESNYEDSK SISRRINDMKNWLKKPSLIQPDSNAQYEEIIEIDLAKVTQPIVACPNDPDNVKEITDVANTNIDEVFIGSCMTNIGHYRA AAKVLEGVQNLKAKLWICPPTKMDEETLKAEGYYKIFEDCGARLELPGCSLCMGNQARVEEGSVVFSTSTRNFDNRLGKN AQVFLGSAELAAVCALLGKIPEIEEYQDITKNKINPYSDELYRYLQFDEIHDFSLTK
Sequences:
>Translated_857_residues MKNMETLLKNYADHVAERAAKGIPPLPLNAEQTNCITKLLEKDSTYDSSYLLDLLINRVPPGVDEAAYVKASWLTAIVNS EKYCKSINPEKAIEILGTMIGGYNVNSLVEILKGENSLLAKKAAEVLKNIILVYDSANEIYELSQNNIYAKEIVNSWANA EWFINKKVLEKEITCLVFKVDGETNTDDLSPAVHATTRPDIPMHALAMLEFKKPDGLKILNNLKKQNLPIAYVGDVVGTG SSRKSAINSLIWHIGEDIAFVPNKKTGGIIIGSKIAPIFFNTAQDSGALPIEADVSQMKTGDVIKIYPYKGIIKKIEKES NTEELISKFELYPSTLTDEIQAGGRINLMIGRSLTDKIRNKLDYQPSEIFTRPQNPTESSAGFTQAQKIVGKACGLDGVR PGMTCEPIMTTVGSQDTTGPMTRDELKELACLGFTADLVMQSFCHTAAYPKPVDLLTHKELPDFISQRGGVALKPGDGII HSWLNRMLLPDTVGTGGDSHTRFPLGISFPGGSGIVAFAAAIGSMPLNMPESVLVKFKGELLPGITLRDLVNAIPLFAIK EGLLTVEKENKKNIFNGKIMEIEGLPNLKLEQAFELTDATAERSCAGSTILLSQETVQEYLKSNICLLEKMVESNYEDSK SISRRINDMKNWLKKPSLIQPDSNAQYEEIIEIDLAKVTQPIVACPNDPDNVKEITDVANTNIDEVFIGSCMTNIGHYRA AAKVLEGVQNLKAKLWICPPTKMDEETLKAEGYYKIFEDCGARLELPGCSLCMGNQARVEEGSVVFSTSTRNFDNRLGKN AQVFLGSAELAAVCALLGKIPEIEEYQDITKNKINPYSDELYRYLQFDEIHDFSLTK >Mature_857_residues MKNMETLLKNYADHVAERAAKGIPPLPLNAEQTNCITKLLEKDSTYDSSYLLDLLINRVPPGVDEAAYVKASWLTAIVNS EKYCKSINPEKAIEILGTMIGGYNVNSLVEILKGENSLLAKKAAEVLKNIILVYDSANEIYELSQNNIYAKEIVNSWANA EWFINKKVLEKEITCLVFKVDGETNTDDLSPAVHATTRPDIPMHALAMLEFKKPDGLKILNNLKKQNLPIAYVGDVVGTG SSRKSAINSLIWHIGEDIAFVPNKKTGGIIIGSKIAPIFFNTAQDSGALPIEADVSQMKTGDVIKIYPYKGIIKKIEKES NTEELISKFELYPSTLTDEIQAGGRINLMIGRSLTDKIRNKLDYQPSEIFTRPQNPTESSAGFTQAQKIVGKACGLDGVR PGMTCEPIMTTVGSQDTTGPMTRDELKELACLGFTADLVMQSFCHTAAYPKPVDLLTHKELPDFISQRGGVALKPGDGII HSWLNRMLLPDTVGTGGDSHTRFPLGISFPGGSGIVAFAAAIGSMPLNMPESVLVKFKGELLPGITLRDLVNAIPLFAIK EGLLTVEKENKKNIFNGKIMEIEGLPNLKLEQAFELTDATAERSCAGSTILLSQETVQEYLKSNICLLEKMVESNYEDSK SISRRINDMKNWLKKPSLIQPDSNAQYEEIIEIDLAKVTQPIVACPNDPDNVKEITDVANTNIDEVFIGSCMTNIGHYRA AAKVLEGVQNLKAKLWICPPTKMDEETLKAEGYYKIFEDCGARLELPGCSLCMGNQARVEEGSVVFSTSTRNFDNRLGKN AQVFLGSAELAAVCALLGKIPEIEEYQDITKNKINPYSDELYRYLQFDEIHDFSLTK
Specific function: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate as well as the dehydration of 2-methylisocitrate to cis-2-methylaconitate [H]
COG id: COG1049
COG function: function code C; Aconitase B
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the aconitase/IPM isomerase family [H]
Homologues:
Organism=Homo sapiens, GI4501867, Length=414, Percent_Identity=24.1545893719807, Blast_Score=67, Evalue=8e-11, Organism=Escherichia coli, GI2367097, Length=860, Percent_Identity=59.0697674418605, Blast_Score=1020, Evalue=0.0, Organism=Escherichia coli, GI1786259, Length=396, Percent_Identity=25.2525252525253, Blast_Score=78, Evalue=3e-15, Organism=Saccharomyces cerevisiae, GI6322261, Length=408, Percent_Identity=25.9803921568627, Blast_Score=85, Evalue=5e-17, Organism=Saccharomyces cerevisiae, GI6321429, Length=407, Percent_Identity=24.5700245700246, Blast_Score=70, Evalue=2e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR015931 - InterPro: IPR015937 - InterPro: IPR001030 - InterPro: IPR015928 - InterPro: IPR018136 - InterPro: IPR004406 - InterPro: IPR015930 - InterPro: IPR015933 - InterPro: IPR015929 [H]
Pfam domain/function: PF00330 Aconitase; PF06434 Aconitase_2_N; PF11791 Aconitase_B_N [H]
EC number: =4.2.1.3; =4.2.1.99 [H]
Molecular weight: Translated: 94432; Mature: 94432
Theoretical pI: Translated: 5.02; Mature: 5.02
Prosite motif: PS00450 ACONITASE_1 ; PS01244 ACONITASE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.9 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 4.2 %Cys+Met (Translated Protein) 1.9 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 4.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKNMETLLKNYADHVAERAAKGIPPLPLNAEQTNCITKLLEKDSTYDSSYLLDLLINRVP CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCC PGVDEAAYVKASWLTAIVNSEKYCKSINPEKAIEILGTMIGGYNVNSLVEILKGENSLLA CCCCCHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHH KKAAEVLKNIILVYDSANEIYELSQNNIYAKEIVNSWANAEWFINKKVLEKEITCLVFKV HHHHHHHHHHEEEECCCHHHHHHCCCCCHHHHHHHHHCCCEEEEHHHHHHCCEEEEEEEE DGETNTDDLSPAVHATTRPDIPMHALAMLEFKKPDGLKILNNLKKQNLPIAYVGDVVGTG CCCCCCCCCCCCEECCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEECCHHCCC SSRKSAINSLIWHIGEDIAFVPNKKTGGIIIGSKIAPIFFNTAQDSGALPIEADVSQMKT CHHHHHHHHHHHHHCCCEEECCCCCCCCEEECCCCCCEEEECCCCCCCCCCCCCHHHCCC GDVIKIYPYKGIIKKIEKESNTEELISKFELYPSTLTDEIQAGGRINLMIGRSLTDKIRN CCEEEECCCHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHCCCEEEEEECCHHHHHHHH KLDYQPSEIFTRPQNPTESSAGFTQAQKIVGKACGLDGVRPGMTCEPIMTTVGSQDTTGP HCCCCHHHHEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCC MTRDELKELACLGFTADLVMQSFCHTAAYPKPVDLLTHKELPDFISQRGGVALKPGDGII CCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCHH HSWLNRMLLPDTVGTGGDSHTRFPLGISFPGGSGIVAFAAAIGSMPLNMPESVLVKFKGE HHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHCCC LLPGITLRDLVNAIPLFAIKEGLLTVEKENKKNIFNGKIMEIEGLPNLKLEQAFELTDAT CCCCCHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHH AERSCAGSTILLSQETVQEYLKSNICLLEKMVESNYEDSKSISRRINDMKNWLKKPSLIQ HHHHCCCCEEEECHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCC PDSNAQYEEIIEIDLAKVTQPIVACPNDPDNVKEITDVANTNIDEVFIGSCMTNIGHYRA CCCCCCHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH AAKVLEGVQNLKAKLWICPPTKMDEETLKAEGYYKIFEDCGARLELPGCSLCMGNQARVE HHHHHHHHHCCCEEEEECCCCCCCHHHHHCCCHHHHHHHCCCEEECCCCCEECCCCCCCC EGSVVFSTSTRNFDNRLGKNAQVFLGSAELAAVCALLGKIPEIEEYQDITKNKINPYSDE CCCEEEEECCCCHHHHHCCCCEEEECCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHH LYRYLQFDEIHDFSLTK HHHHHHHHCCCCCCCCC >Mature Secondary Structure MKNMETLLKNYADHVAERAAKGIPPLPLNAEQTNCITKLLEKDSTYDSSYLLDLLINRVP CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCC PGVDEAAYVKASWLTAIVNSEKYCKSINPEKAIEILGTMIGGYNVNSLVEILKGENSLLA CCCCCHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHH KKAAEVLKNIILVYDSANEIYELSQNNIYAKEIVNSWANAEWFINKKVLEKEITCLVFKV HHHHHHHHHHEEEECCCHHHHHHCCCCCHHHHHHHHHCCCEEEEHHHHHHCCEEEEEEEE DGETNTDDLSPAVHATTRPDIPMHALAMLEFKKPDGLKILNNLKKQNLPIAYVGDVVGTG CCCCCCCCCCCCEECCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEECCHHCCC SSRKSAINSLIWHIGEDIAFVPNKKTGGIIIGSKIAPIFFNTAQDSGALPIEADVSQMKT CHHHHHHHHHHHHHCCCEEECCCCCCCCEEECCCCCCEEEECCCCCCCCCCCCCHHHCCC GDVIKIYPYKGIIKKIEKESNTEELISKFELYPSTLTDEIQAGGRINLMIGRSLTDKIRN CCEEEECCCHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHCCCEEEEEECCHHHHHHHH KLDYQPSEIFTRPQNPTESSAGFTQAQKIVGKACGLDGVRPGMTCEPIMTTVGSQDTTGP HCCCCHHHHEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCC MTRDELKELACLGFTADLVMQSFCHTAAYPKPVDLLTHKELPDFISQRGGVALKPGDGII CCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCHH HSWLNRMLLPDTVGTGGDSHTRFPLGISFPGGSGIVAFAAAIGSMPLNMPESVLVKFKGE HHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHCCC LLPGITLRDLVNAIPLFAIKEGLLTVEKENKKNIFNGKIMEIEGLPNLKLEQAFELTDAT CCCCCHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHH AERSCAGSTILLSQETVQEYLKSNICLLEKMVESNYEDSKSISRRINDMKNWLKKPSLIQ HHHHCCCCEEEECHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCC PDSNAQYEEIIEIDLAKVTQPIVACPNDPDNVKEITDVANTNIDEVFIGSCMTNIGHYRA CCCCCCHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH AAKVLEGVQNLKAKLWICPPTKMDEETLKAEGYYKIFEDCGARLELPGCSLCMGNQARVE HHHHHHHHHCCCEEEEECCCCCCCHHHHHCCCHHHHHHHCCCEEECCCCCEECCCCCCCC EGSVVFSTSTRNFDNRLGKNAQVFLGSAELAAVCALLGKIPEIEEYQDITKNKINPYSDE CCCEEEEECCCCHHHHHCCCCEEEECCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHH LYRYLQFDEIHDFSLTK HHHHHHHHCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8905231 [H]