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The map label for this gene is rnc [H]

Identifier: 126697134

GI number: 126697134

Start: 1518722

End: 1519471

Strand: Direct

Name: rnc [H]

Synonym: P9301_17961

Alternate gene names: 126697134

Gene position: 1518722-1519471 (Clockwise)

Preceding gene: 126697131

Following gene: 126697136

Centisome position: 92.5

GC content: 28.0

Gene sequence:

>750_bases
ATGACAAATATAATTAACACAAAGAGAATTAATCAAATAACTACTTTTTTAAAGTCTTTAAATATAAAATCAAAAAGATT
TTCTGAAATAATTGAAACTCAAAACATTTCAGTTATTCAAGATTTTAACCAAGCATTTATCCATTCCTCTGAGGACAAAA
TAATAAATTATGAAAAACTAGAATTTTTCGGAGATGCAGTACTCAGATTAGCTGCTTCTAATTTTATTGAAAAAAAATAT
CCTCAATTAAGTGTAGGAGAAAGATCAGAGCTAAGAGCACAAATTGTAAGTGATGAATGGCTAACTAAATTAGGGAGAAA
AATTGAAATAGATAAATTAATAATTAAAGGACCTAAAGCTCTTGGTGATGAAAATTCAAAAAATACTATTATTGGAGAGG
CTACAGAAGCTTTAATAGGTGCTGTTTACAAGTGCTTTAATTCAATTCAGGAAATAAACCTTTGGTTAGATAATATTTGG
GAGGAAGATTCAGAACAATTTTTAAAAGCTCCATATAAATACAAATCTAAGACAGTATTGCAAGAGTGGTGTCAAAGTAA
AGGTTTTGATTTGCCAGTCTATAAAATAATGGAAGTCTCAAAAAAAAATGGAGACCTTAAAAGATTTTCTTGCGATATTT
TTATTGAAGGATTAAAAGAATCATCTGCATTCGGGAAGTCCCATAAACAAGCAGAAACAAATGCAGCTAGAGTTTTGATA
GAAAAATTTATAACTAAAGGTAAAATCTAA

Upstream 100 bases:

>100_bases
AAGTAATTCCAGTCCTAGATAGATGATCGCCCATCTTAATTAAGATGAACAGAACCCGGCTTACGACCTGCTTTCTAATT
GTTTTGATTATTAAAATCAG

Downstream 100 bases:

>100_bases
TTTTTAAACTATTTCTAAATTCGTTAGCTGAAAAGTTATGAGCTTATCCCAATTACCTCCTTCAAACAATACTGCTGCTC
TTTTTTTGGTAACTCTTTGT

Product: putative ribonuclease III

Products: NA

Alternate protein names: Ribonuclease III 2; RNase III 2 [H]

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MTNIINTKRINQITTFLKSLNIKSKRFSEIIETQNISVIQDFNQAFIHSSEDKIINYEKLEFFGDAVLRLAASNFIEKKY
PQLSVGERSELRAQIVSDEWLTKLGRKIEIDKLIIKGPKALGDENSKNTIIGEATEALIGAVYKCFNSIQEINLWLDNIW
EEDSEQFLKAPYKYKSKTVLQEWCQSKGFDLPVYKIMEVSKKNGDLKRFSCDIFIEGLKESSAFGKSHKQAETNAARVLI
EKFITKGKI

Sequences:

>Translated_249_residues
MTNIINTKRINQITTFLKSLNIKSKRFSEIIETQNISVIQDFNQAFIHSSEDKIINYEKLEFFGDAVLRLAASNFIEKKY
PQLSVGERSELRAQIVSDEWLTKLGRKIEIDKLIIKGPKALGDENSKNTIIGEATEALIGAVYKCFNSIQEINLWLDNIW
EEDSEQFLKAPYKYKSKTVLQEWCQSKGFDLPVYKIMEVSKKNGDLKRFSCDIFIEGLKESSAFGKSHKQAETNAARVLI
EKFITKGKI
>Mature_248_residues
TNIINTKRINQITTFLKSLNIKSKRFSEIIETQNISVIQDFNQAFIHSSEDKIINYEKLEFFGDAVLRLAASNFIEKKYP
QLSVGERSELRAQIVSDEWLTKLGRKIEIDKLIIKGPKALGDENSKNTIIGEATEALIGAVYKCFNSIQEINLWLDNIWE
EDSEQFLKAPYKYKSKTVLQEWCQSKGFDLPVYKIMEVSKKNGDLKRFSCDIFIEGLKESSAFGKSHKQAETNAARVLIE
KFITKGKI

Specific function: Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs [H]

COG id: COG0571

COG function: function code K; dsRNA-specific ribonuclease

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase III domain [H]

Homologues:

Organism=Escherichia coli, GI1788920, Length=181, Percent_Identity=28.1767955801105, Blast_Score=82, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001159
- InterPro:   IPR014720
- InterPro:   IPR000999
- InterPro:   IPR011907 [H]

Pfam domain/function: PF00035 dsrm; PF00636 Ribonuclease_3 [H]

EC number: =3.1.26.3 [H]

Molecular weight: Translated: 28572; Mature: 28441

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: PS50137 DS_RBD ; PS50142 RNASE_3_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNIINTKRINQITTFLKSLNIKSKRFSEIIETQNISVIQDFNQAFIHSSEDKIINYEKL
CCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHH
EFFGDAVLRLAASNFIEKKYPQLSVGERSELRAQIVSDEWLTKLGRKIEIDKLIIKGPKA
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEHHHHEEECCHH
LGDENSKNTIIGEATEALIGAVYKCFNSIQEINLWLDNIWEEDSEQFLKAPYKYKSKTVL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHH
QEWCQSKGFDLPVYKIMEVSKKNGDLKRFSCDIFIEGLKESSAFGKSHKQAETNAARVLI
HHHHHHCCCCCHHHHHHHHHHCCCCHHHEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
EKFITKGKI
HHHHHCCCC
>Mature Secondary Structure 
TNIINTKRINQITTFLKSLNIKSKRFSEIIETQNISVIQDFNQAFIHSSEDKIINYEKL
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHH
EFFGDAVLRLAASNFIEKKYPQLSVGERSELRAQIVSDEWLTKLGRKIEIDKLIIKGPKA
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEHHHHEEECCHH
LGDENSKNTIIGEATEALIGAVYKCFNSIQEINLWLDNIWEEDSEQFLKAPYKYKSKTVL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHH
QEWCQSKGFDLPVYKIMEVSKKNGDLKRFSCDIFIEGLKESSAFGKSHKQAETNAARVLI
HHHHHHCCCCCHHHHHHHHHHCCCCHHHEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
EKFITKGKI
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]