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The map label for this gene is bioD [H]

Identifier: 126696999

GI number: 126696999

Start: 1391770

End: 1392468

Strand: Direct

Name: bioD [H]

Synonym: P9301_16611

Alternate gene names: 126696999

Gene position: 1391770-1392468 (Clockwise)

Preceding gene: 126696998

Following gene: 126697000

Centisome position: 84.77

GC content: 29.47

Gene sequence:

>699_bases
ATGGCAAATTCAGATTCAAATCATAAAGAAATTATGAGTAGTCAGGATAGTATTTTCAAATTTATAATTTGTGGAACAGA
TACTGATATTGGAAAAACTTTAATAAGCTCTTTTTTTGTTAAAGGATTAAATTCCTTTTATTGGAAGCCTATTCAAAGTG
GTATTGAATCGCAAACTGATAGTCAAACTGTTGAAAAACTTGCACAAGTAAATAGAGAGAAAATAATCAAAGAAGCTTAT
GTCTTTACCAAACCCCTATCTCCTCATTGGGCTGCTGAAATAGATCAAAAAACTATTAACTTTGATAAGTTAAGATTGCC
AAAAGTACAAGGCCCATTAATTATAGAAACTGCAGGTGGATTAATGGTTCCAATAACACGCAATTTTTTGCAAATAGATC
AAATAAAACAATGGAATCTTCCGGTAATACTTGTATGTAAGAGCTCACTTGGGACTCTCAACCATACCCTGCTTAGTATT
GAGGCCTTAAAAAGAAGAAATATTGAAATTTTAGGTTTAGTAGTAAATGGCGAAAAACACCTAGATAATCCAAAAACTCT
AGTTGATTTTAGTGGTATTCCATTAATTACCGAATTTCCTTATATAAAAAAAATGGACTCAAATAATTTAGATAAACTAT
GGGAAGAACTTGAAATTAAAAATAAATTAATCTCACTTTTAAATTCCAAAATAAGTTAA

Upstream 100 bases:

>100_bases
TAGGAGCACAATCAACAAATTGTAAACGCAAAACCGTGAAGGAGTTAAAAAAAATTCAAAAGTTTTGGCCAAAGAATTAC
AATAATACAGTGGACCTTTC

Downstream 100 bases:

>100_bases
ATGAAACCTTTGGATTCAAAAACTCCAAATCAAGATTGGCACCCAAATATTTGGCCACCTTTTACTCAAGTCAATAAGAG
TAAGCCGCAAATAGAAGTAA

Product: putative dethiobiotin synthase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MANSDSNHKEIMSSQDSIFKFIICGTDTDIGKTLISSFFVKGLNSFYWKPIQSGIESQTDSQTVEKLAQVNREKIIKEAY
VFTKPLSPHWAAEIDQKTINFDKLRLPKVQGPLIIETAGGLMVPITRNFLQIDQIKQWNLPVILVCKSSLGTLNHTLLSI
EALKRRNIEILGLVVNGEKHLDNPKTLVDFSGIPLITEFPYIKKMDSNNLDKLWEELEIKNKLISLLNSKIS

Sequences:

>Translated_232_residues
MANSDSNHKEIMSSQDSIFKFIICGTDTDIGKTLISSFFVKGLNSFYWKPIQSGIESQTDSQTVEKLAQVNREKIIKEAY
VFTKPLSPHWAAEIDQKTINFDKLRLPKVQGPLIIETAGGLMVPITRNFLQIDQIKQWNLPVILVCKSSLGTLNHTLLSI
EALKRRNIEILGLVVNGEKHLDNPKTLVDFSGIPLITEFPYIKKMDSNNLDKLWEELEIKNKLISLLNSKIS
>Mature_231_residues
ANSDSNHKEIMSSQDSIFKFIICGTDTDIGKTLISSFFVKGLNSFYWKPIQSGIESQTDSQTVEKLAQVNREKIIKEAYV
FTKPLSPHWAAEIDQKTINFDKLRLPKVQGPLIIETAGGLMVPITRNFLQIDQIKQWNLPVILVCKSSLGTLNHTLLSIE
ALKRRNIEILGLVVNGEKHLDNPKTLVDFSGIPLITEFPYIKKMDSNNLDKLWEELEIKNKLISLLNSKIS

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=210, Percent_Identity=26.6666666666667, Blast_Score=89, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6324385, Length=206, Percent_Identity=36.4077669902913, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472 [H]

Pfam domain/function: NA

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 26268; Mature: 26137

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANSDSNHKEIMSSQDSIFKFIICGTDTDIGKTLISSFFVKGLNSFYWKPIQSGIESQTD
CCCCCCCHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
SQTVEKLAQVNREKIIKEAYVFTKPLSPHWAAEIDQKTINFDKLRLPKVQGPLIIETAGG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEECCCCCCCEEEEECCC
LMVPITRNFLQIDQIKQWNLPVILVCKSSLGTLNHTLLSIEALKRRNIEILGLVVNGEKH
EEEECHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEEEEECHHH
LDNPKTLVDFSGIPLITEFPYIKKMDSNNLDKLWEELEIKNKLISLLNSKIS
CCCCCEEEECCCCCEEECCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ANSDSNHKEIMSSQDSIFKFIICGTDTDIGKTLISSFFVKGLNSFYWKPIQSGIESQTD
CCCCCCHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
SQTVEKLAQVNREKIIKEAYVFTKPLSPHWAAEIDQKTINFDKLRLPKVQGPLIIETAGG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEECCCCCCCEEEEECCC
LMVPITRNFLQIDQIKQWNLPVILVCKSSLGTLNHTLLSIEALKRRNIEILGLVVNGEKH
EEEECHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEEEEECHHH
LDNPKTLVDFSGIPLITEFPYIKKMDSNNLDKLWEELEIKNKLISLLNSKIS
CCCCCEEEECCCCCEEECCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA