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The map label for this gene is fabG [C]

Identifier: 126696887

GI number: 126696887

Start: 1313364

End: 1314293

Strand: Direct

Name: fabG [C]

Synonym: P9301_15491

Alternate gene names: 126696887

Gene position: 1313364-1314293 (Clockwise)

Preceding gene: 126696886

Following gene: 126696889

Centisome position: 79.99

GC content: 33.87

Gene sequence:

>930_bases
ATGACTGCCACTATTTCAAGACCTAAAATCTCTAACTGGGAAACATCTAATATTCCAAACCTTACAGGCAAAATAGCGCT
AATTACTGGTGCAAATAGTGGTCTTGGATACTACACTGCAAAGGCTTTAGCAGAAAAAAATGCTCATGTTGTTATAGCTT
GTAGATCACTTGAAAAAGCTAATCAAACTATCAAAAAACTTAAAGGTCTTAATCCTGAAGGATTATTTACACCTTTAGAA
TTAGATTTGTCAGATTTAAAAAATATTGTTGAAGTTCAGTCCAAAATTTTTGATAATTTTGAAAATTTGGATTTACTAAT
CAATAATGCAGGCATTATGCATCCGCCTAAAACTCTTAGTGCCCAAGGATATGAAATACAATTTGCAGTTAATCATCTAG
CTCACATGCTTTTGACTCTCAAGCTACTTCCAATTATTGAAAAAAAAGAAGAATCTAGAATAGTTACGGTGACTTCAGGA
GCACAATTTTTTGGCAAAGTCGGTTGGAAAAATCTGAAAGCCGAGAACTATTACAACAAATGGGAATCTTACTCCAATAG
CAAATTGGCAAATGTAATGTTTGCTTTGGAACTAAATGAGAACTTAAAGCACAAAAATATACTTTCTTTAGCTGCTCACC
CAGGAATTGCAAAAACAAATCTCTTTACTGCTCAAAAACCTAACCCTGGACCATTAGAAACATTCTCATTGGAATTATTT
AGTCCTATTTTTCAAACTGCTGAGATGGGTGCTTTACCTCAGCTTTTTGCAGCTACTTCACCAGACGCAAGAGGCGGTGA
TCATTATGGTCCTAGATTTAATTTCAGAGGTCATCCAAAACTATCCCCTACTTCTCCTTTCGCTATGAATAAAAAAGAAA
GAAAAAATTTATGGGAAAAAAGCCTCGAAATTATTAATAACTTCTTATAA

Upstream 100 bases:

>100_bases
TAGTACCTTCAATAAGAGCTCACGATAGTGACTTCCAGTATTTACAGTAGAAAAGTAATTAAATTTTGGTTAAATTCCAA
AGCAATTTGCAGGATTACTA

Downstream 100 bases:

>100_bases
ATTTTTCATTTTTACTAACTTGAGAAAATACTTCAAGATATGTAATTCACTCTCTGAGAGTTTCATAAATTCTGTTAAGG
CATCGTAATTTTTTTCATCA

Product: short-chain dehydrogenase/reductase

Products: protochlorophyllide; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTATISRPKISNWETSNIPNLTGKIALITGANSGLGYYTAKALAEKNAHVVIACRSLEKANQTIKKLKGLNPEGLFTPLE
LDLSDLKNIVEVQSKIFDNFENLDLLINNAGIMHPPKTLSAQGYEIQFAVNHLAHMLLTLKLLPIIEKKEESRIVTVTSG
AQFFGKVGWKNLKAENYYNKWESYSNSKLANVMFALELNENLKHKNILSLAAHPGIAKTNLFTAQKPNPGPLETFSLELF
SPIFQTAEMGALPQLFAATSPDARGGDHYGPRFNFRGHPKLSPTSPFAMNKKERKNLWEKSLEIINNFL

Sequences:

>Translated_309_residues
MTATISRPKISNWETSNIPNLTGKIALITGANSGLGYYTAKALAEKNAHVVIACRSLEKANQTIKKLKGLNPEGLFTPLE
LDLSDLKNIVEVQSKIFDNFENLDLLINNAGIMHPPKTLSAQGYEIQFAVNHLAHMLLTLKLLPIIEKKEESRIVTVTSG
AQFFGKVGWKNLKAENYYNKWESYSNSKLANVMFALELNENLKHKNILSLAAHPGIAKTNLFTAQKPNPGPLETFSLELF
SPIFQTAEMGALPQLFAATSPDARGGDHYGPRFNFRGHPKLSPTSPFAMNKKERKNLWEKSLEIINNFL
>Mature_308_residues
TATISRPKISNWETSNIPNLTGKIALITGANSGLGYYTAKALAEKNAHVVIACRSLEKANQTIKKLKGLNPEGLFTPLEL
DLSDLKNIVEVQSKIFDNFENLDLLINNAGIMHPPKTLSAQGYEIQFAVNHLAHMLLTLKLLPIIEKKEESRIVTVTSGA
QFFGKVGWKNLKAENYYNKWESYSNSKLANVMFALELNENLKHKNILSLAAHPGIAKTNLFTAQKPNPGPLETFSLELFS
PIFQTAEMGALPQLFAATSPDARGGDHYGPRFNFRGHPKLSPTSPFAMNKKERKNLWEKSLEIINNFL

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI166795268, Length=308, Percent_Identity=32.1428571428571, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI186928839, Length=289, Percent_Identity=33.9100346020761, Blast_Score=151, Evalue=8e-37,
Organism=Homo sapiens, GI225579078, Length=289, Percent_Identity=33.9100346020761, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI10190746, Length=324, Percent_Identity=33.641975308642, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI7706523, Length=299, Percent_Identity=28.4280936454849, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI146231950, Length=286, Percent_Identity=33.2167832167832, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI19923931, Length=255, Percent_Identity=32.5490196078431, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI193804850, Length=290, Percent_Identity=31.0344827586207, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI13375997, Length=169, Percent_Identity=33.1360946745562, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI142976729, Length=185, Percent_Identity=31.3513513513514, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI72534732, Length=169, Percent_Identity=33.1360946745562, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI40548397, Length=209, Percent_Identity=30.1435406698565, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI214010158, Length=209, Percent_Identity=30.1435406698565, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI214010156, Length=209, Percent_Identity=30.1435406698565, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI22758144, Length=209, Percent_Identity=30.1435406698565, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI109715829, Length=137, Percent_Identity=29.9270072992701, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1787335, Length=207, Percent_Identity=28.5024154589372, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786701, Length=232, Percent_Identity=28.448275862069, Blast_Score=64, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17558006, Length=293, Percent_Identity=29.6928327645051, Blast_Score=117, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI17532791, Length=307, Percent_Identity=28.0130293159609, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI193207620, Length=307, Percent_Identity=28.9902280130293, Blast_Score=104, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17532805, Length=303, Percent_Identity=28.0528052805281, Blast_Score=104, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI72001364, Length=293, Percent_Identity=30.3754266211604, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17505416, Length=214, Percent_Identity=32.7102803738318, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71992402, Length=254, Percent_Identity=28.3464566929134, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17535059, Length=253, Percent_Identity=28.8537549407115, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI32565532, Length=207, Percent_Identity=29.951690821256, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI115533174, Length=296, Percent_Identity=27.3648648648649, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI115533172, Length=293, Percent_Identity=26.962457337884, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=177, Percent_Identity=30.5084745762712, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17558996, Length=214, Percent_Identity=28.9719626168224, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324820, Length=310, Percent_Identity=28.0645161290323, Blast_Score=108, Evalue=9e-25,
Organism=Saccharomyces cerevisiae, GI6322227, Length=270, Percent_Identity=24.4444444444444, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI22024069, Length=286, Percent_Identity=36.3636363636364, Blast_Score=144, Evalue=6e-35,
Organism=Drosophila melanogaster, GI45554248, Length=285, Percent_Identity=33.3333333333333, Blast_Score=144, Evalue=7e-35,
Organism=Drosophila melanogaster, GI24640117, Length=285, Percent_Identity=33.3333333333333, Blast_Score=144, Evalue=7e-35,
Organism=Drosophila melanogaster, GI28573296, Length=247, Percent_Identity=37.246963562753, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI19921754, Length=284, Percent_Identity=36.6197183098592, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24586328, Length=285, Percent_Identity=32.6315789473684, Blast_Score=138, Evalue=5e-33,
Organism=Drosophila melanogaster, GI161076371, Length=251, Percent_Identity=35.0597609561753, Blast_Score=127, Evalue=7e-30,
Organism=Drosophila melanogaster, GI20129347, Length=255, Percent_Identity=30.1960784313725, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24656154, Length=249, Percent_Identity=34.136546184739, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI19922628, Length=249, Percent_Identity=34.136546184739, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI45553409, Length=286, Percent_Identity=29.3706293706294, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24647948, Length=286, Percent_Identity=29.3706293706294, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24647946, Length=286, Percent_Identity=29.3706293706294, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24647931, Length=233, Percent_Identity=28.3261802575107, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21358495, Length=206, Percent_Identity=29.6116504854369, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24643142, Length=160, Percent_Identity=34.375, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.3.1.33

Molecular weight: Translated: 34376; Mature: 34245

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATISRPKISNWETSNIPNLTGKIALITGANSGLGYYTAKALAEKNAHVVIACRSLEKA
CCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCEEEEEECCHHHH
NQTIKKLKGLNPEGLFTPLELDLSDLKNIVEVQSKIFDNFENLDLLINNAGIMHPPKTLS
HHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCC
AQGYEIQFAVNHLAHMLLTLKLLPIIEKKEESRIVTVTSGAQFFGKVGWKNLKAENYYNK
CCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHCCCCCCCCHHHHHH
WESYSNSKLANVMFALELNENLKHKNILSLAAHPGIAKTNLFTAQKPNPGPLETFSLELF
HHHCCCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCEEECCCCCCCCCHHHHHHHH
SPIFQTAEMGALPQLFAATSPDARGGDHYGPRFNFRGHPKLSPTSPFAMNKKERKNLWEK
HHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
SLEIINNFL
HHHHHHHCC
>Mature Secondary Structure 
TATISRPKISNWETSNIPNLTGKIALITGANSGLGYYTAKALAEKNAHVVIACRSLEKA
CCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCEEEEEECCHHHH
NQTIKKLKGLNPEGLFTPLELDLSDLKNIVEVQSKIFDNFENLDLLINNAGIMHPPKTLS
HHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCC
AQGYEIQFAVNHLAHMLLTLKLLPIIEKKEESRIVTVTSGAQFFGKVGWKNLKAENYYNK
CCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHCCCCCCCCHHHHHH
WESYSNSKLANVMFALELNENLKHKNILSLAAHPGIAKTNLFTAQKPNPGPLETFSLELF
HHHCCCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCEEECCCCCCCCCHHHHHHHH
SPIFQTAEMGALPQLFAATSPDARGGDHYGPRFNFRGHPKLSPTSPFAMNKKERKNLWEK
HHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
SLEIINNFL
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: chlorophyllide a; NADP+

Specific reaction: chlorophyllide a + NADP+ = protochlorophyllide + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383668 [H]