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The map label for this gene is kdsB [H]

Identifier: 126696741

GI number: 126696741

Start: 1170704

End: 1171447

Strand: Direct

Name: kdsB [H]

Synonym: P9301_14031

Alternate gene names: 126696741

Gene position: 1170704-1171447 (Clockwise)

Preceding gene: 126696740

Following gene: 126696742

Centisome position: 71.3

GC content: 28.49

Gene sequence:

>744_bases
ATGAAAACTATAGGATTAATCCCTGCAAGAATGGGAAGTTCGAGATTACAAGGGAAACCTTTAAAAAAGATAAAAGGTAA
AGAGATGCTCTTAAGAGTATATGAAAATGCATTAAATGCAAAATTAATAGATACTCTTTATATAGCTACTTGTGATGAAG
AAATAAGAAGAACAATGGATGCATACGGATGCAAGGTAGTCATGACTGGTTCACACCACACAAGATGTACTTCTAGATGT
GCAGAAGCATTGATAAAAATAGAAAAAACATGTAATTATACTTTCGATAATATTGTTATGATTCAGGGAGATGAACCTTT
GGTAAAGGGTGCTGAAATCGATGAAGCAGTTAAATTAATTATTGACAACAAGGATATTAGAATTGCAAATCTTATAGGAA
AAATTGAAAGCTATGAAGAATTTACCGATAGGAACACTATAAAAGTGGTTCTAACAAAAAATGACGAAATACTTTATTTT
TCTAGAGGAAATATTCCATTCTCTGAGAAAGATAATTTTAAATATGCTTTTAAACAGGTATGTATCATTCCAATGAAAAG
AGATATACTTGAAATTTTTACAAAATTTGAAGAGACTACTTTAGAGAAAATTGAATCAATAGATATGCTTAGATTAATTG
AAAATAAAATTCCTATAAAAGCAAAATTAATCAAATATAAAACTCAAGCAGTAGATGTTCCTTCTGATATTAAGAAAGTT
GAGAAAATACTCACAAATGAATAA

Upstream 100 bases:

>100_bases
AAGCAATAAAAAAAGGATTCACATTTTTACCATATAGTATCGATACAGTATTCTTAAGGAAAGCTTCTAAAAAGCCTAAT
AATATCCATTATCAAAAAAA

Downstream 100 bases:

>100_bases
AACTCTAAAAGAATACAATAAAAAGCTTAGTGAATTATCCTTAATATTTGGTCCAAAATCATTATTTTCTCCAACTTTAT
GCAGGATAGAAGGTCAAACA

Product: CMP-2-keto-3-deoxyoctulosonic acid synthetase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MKTIGLIPARMGSSRLQGKPLKKIKGKEMLLRVYENALNAKLIDTLYIATCDEEIRRTMDAYGCKVVMTGSHHTRCTSRC
AEALIKIEKTCNYTFDNIVMIQGDEPLVKGAEIDEAVKLIIDNKDIRIANLIGKIESYEEFTDRNTIKVVLTKNDEILYF
SRGNIPFSEKDNFKYAFKQVCIIPMKRDILEIFTKFEETTLEKIESIDMLRLIENKIPIKAKLIKYKTQAVDVPSDIKKV
EKILTNE

Sequences:

>Translated_247_residues
MKTIGLIPARMGSSRLQGKPLKKIKGKEMLLRVYENALNAKLIDTLYIATCDEEIRRTMDAYGCKVVMTGSHHTRCTSRC
AEALIKIEKTCNYTFDNIVMIQGDEPLVKGAEIDEAVKLIIDNKDIRIANLIGKIESYEEFTDRNTIKVVLTKNDEILYF
SRGNIPFSEKDNFKYAFKQVCIIPMKRDILEIFTKFEETTLEKIESIDMLRLIENKIPIKAKLIKYKTQAVDVPSDIKKV
EKILTNE
>Mature_247_residues
MKTIGLIPARMGSSRLQGKPLKKIKGKEMLLRVYENALNAKLIDTLYIATCDEEIRRTMDAYGCKVVMTGSHHTRCTSRC
AEALIKIEKTCNYTFDNIVMIQGDEPLVKGAEIDEAVKLIIDNKDIRIANLIGKIESYEEFTDRNTIKVVLTKNDEILYF
SRGNIPFSEKDNFKYAFKQVCIIPMKRDILEIFTKFEETTLEKIESIDMLRLIENKIPIKAKLIKYKTQAVDVPSDIKKV
EKILTNE

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=252, Percent_Identity=31.3492063492063, Blast_Score=113, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 28363; Mature: 28363

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIGLIPARMGSSRLQGKPLKKIKGKEMLLRVYENALNAKLIDTLYIATCDEEIRRTMD
CCCCCCCCCCCCCCCCCCCCHHHHCHHHHHHHHHHHHHCHHHHHHHEEEECCHHHHHHHH
AYGCKVVMTGSHHTRCTSRCAEALIKIEKTCNYTFDNIVMIQGDEPLVKGAEIDEAVKLI
HHCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHEE
IDNKDIRIANLIGKIESYEEFTDRNTIKVVLTKNDEILYFSRGNIPFSEKDNFKYAFKQV
ECCCCEEHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHH
CIIPMKRDILEIFTKFEETTLEKIESIDMLRLIENKIPIKAKLIKYKTQAVDVPSDIKKV
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHEEHHHHHCCCCHHHHHH
EKILTNE
HHHHCCC
>Mature Secondary Structure
MKTIGLIPARMGSSRLQGKPLKKIKGKEMLLRVYENALNAKLIDTLYIATCDEEIRRTMD
CCCCCCCCCCCCCCCCCCCCHHHHCHHHHHHHHHHHHHCHHHHHHHEEEECCHHHHHHHH
AYGCKVVMTGSHHTRCTSRCAEALIKIEKTCNYTFDNIVMIQGDEPLVKGAEIDEAVKLI
HHCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHEE
IDNKDIRIANLIGKIESYEEFTDRNTIKVVLTKNDEILYFSRGNIPFSEKDNFKYAFKQV
ECCCCEEHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHH
CIIPMKRDILEIFTKFEETTLEKIESIDMLRLIENKIPIKAKLIKYKTQAVDVPSDIKKV
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHEEHHHHHCCCCHHHHHH
EKILTNE
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA