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The map label for this gene is cobU [C]

Identifier: 126696335

GI number: 126696335

Start: 868168

End: 868728

Strand: Direct

Name: cobU [C]

Synonym: P9301_09971

Alternate gene names: 126696335

Gene position: 868168-868728 (Clockwise)

Preceding gene: 126696334

Following gene: 126696336

Centisome position: 52.88

GC content: 29.41

Gene sequence:

>561_bases
ATGAATGCCAATGATTTAAGTATTAGTGAATATTCATCTCATATAGTTTTTATTACAGGAGGGACAAAGAGTGGGAAAAG
TGAATTCGCAGAGTATCTTGCAAAGAAAGTAAAAAAATTATCATATGTTGCCTTATCTGAAAACAATTTGGATGATAAAG
ATTGGCAAGATAAAATTAAATTACATCGAGAAAGAAGGCCAAAAGATTGGAAATTAATAGAAACGACAGATCTATTAAAT
ACATTAAGGAAAGAAGAAGGTCCACTATTAGTAGATTCTATTGGCGGATTCGTTATGAAAAGTATTGGGAAGGAACAAAA
TGAATGGTCAATAAAAATGAATTTACTTATGAGTCTCTTAATGAAAAGAAAAAGCATAACAATTATTGTTGGAGAACAAG
TAGGTTGGAGTCTCGTCTCTGAATATAAAATTGGTAATACTTATATTGAAAGAATTGGCGAACTTCAAAAGAGAATAACC
AAAATATCAAAAGATAATTGGTTGGCAATAAATGGTAGAGCAATCAAAATAGATGAAATAAGTATTGAAATACCTACTTA
A

Upstream 100 bases:

>100_bases
GAGAGTTCAACTGCTACTTATATAGTAATAGGTTTGTTAATTGCTGCCACAATTATTCCTCTAGCAACATGGTGGTATTT
CTCTAAATAATAGAGAATTT

Downstream 100 bases:

>100_bases
AATTGGAAGTCGCTCTTTTTGAACCTAGAATACCACAAAATACTGGTAATATTGCCAGATCATGTGCTGCGTTTGATATA
CCTTTAAATCTTATAGAGCC

Product: putative cobinamide kinase

Products: Adenosyl cobinamide phosphate; RDP

Alternate protein names: Cobinamide Kinase; Cobalbumin Biosynthesis Protein; Adenosylcobinamide-Phosphate Guanylyltransferase; Adenosylcobinamide-Phosphateguanylyltransferase; Cobalbumin Biosynthesis; Cobinamide Kinase/Cobinamide Phosphate Guanylyltransferase; Bifunctional Cobalamin Biosynthesis Protein CobU; Cobinamide Kinase / Conamide Phosphate Guanylyltransferase; Bifunctional Protein Adenosylcobinamide Kinase; Cobalamin Biosynthesis Protein; CobU Bifunctional Cobalamin Biosynthesis Pyrophosphate; Bifunctional Cobalamin Biosynthesis Protein; ATPase; Cobinamide Kinase And Guanylyltransferase; Cobinamide Kinase / Cobinamide Phosphate Guanyltransferase; Bifunctional Adenosylcobalamin Biosynthesis Protein CobU

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MNANDLSISEYSSHIVFITGGTKSGKSEFAEYLAKKVKKLSYVALSENNLDDKDWQDKIKLHRERRPKDWKLIETTDLLN
TLRKEEGPLLVDSIGGFVMKSIGKEQNEWSIKMNLLMSLLMKRKSITIIVGEQVGWSLVSEYKIGNTYIERIGELQKRIT
KISKDNWLAINGRAIKIDEISIEIPT

Sequences:

>Translated_186_residues
MNANDLSISEYSSHIVFITGGTKSGKSEFAEYLAKKVKKLSYVALSENNLDDKDWQDKIKLHRERRPKDWKLIETTDLLN
TLRKEEGPLLVDSIGGFVMKSIGKEQNEWSIKMNLLMSLLMKRKSITIIVGEQVGWSLVSEYKIGNTYIERIGELQKRIT
KISKDNWLAINGRAIKIDEISIEIPT
>Mature_186_residues
MNANDLSISEYSSHIVFITGGTKSGKSEFAEYLAKKVKKLSYVALSENNLDDKDWQDKIKLHRERRPKDWKLIETTDLLN
TLRKEEGPLLVDSIGGFVMKSIGKEQNEWSIKMNLLMSLLMKRKSITIIVGEQVGWSLVSEYKIGNTYIERIGELQKRIT
KISKDNWLAINGRAIKIDEISIEIPT

Specific function: ATP-Dependent Phosphorylation Of Adenosylcobinamide And Adds GMP To Adenosylcobinamide Phosphate. [C]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=181, Percent_Identity=22.6519337016575, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.1.156; 2.7.7.62

Molecular weight: Translated: 21302; Mature: 21302

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNANDLSISEYSSHIVFITGGTKSGKSEFAEYLAKKVKKLSYVALSENNLDDKDWQDKIK
CCCCCCCHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHH
LHRERRPKDWKLIETTDLLNTLRKEEGPLLVDSIGGFVMKSIGKEQNEWSIKMNLLMSLL
HHHHCCCCCCEEEHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHH
MKRKSITIIVGEQVGWSLVSEYKIGNTYIERIGELQKRITKISKDNWLAINGRAIKIDEI
HCCCCEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEEEE
SIEIPT
EEEECC
>Mature Secondary Structure
MNANDLSISEYSSHIVFITGGTKSGKSEFAEYLAKKVKKLSYVALSENNLDDKDWQDKIK
CCCCCCCHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHH
LHRERRPKDWKLIETTDLLNTLRKEEGPLLVDSIGGFVMKSIGKEQNEWSIKMNLLMSLL
HHHHCCCCCCEEEHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHH
MKRKSITIIVGEQVGWSLVSEYKIGNTYIERIGELQKRITKISKDNWLAINGRAIKIDEI
HCCCCEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEEEE
SIEIPT
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RTP; Adenosyl cobinamide

Specific reaction: RTP + adenosylcobinamide = adenosylcobinamide phosphate + RDP

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA