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The map label for this gene is argC

Identifier: 126696305

GI number: 126696305

Start: 834362

End: 835417

Strand: Direct

Name: argC

Synonym: P9301_09671

Alternate gene names: 126696305

Gene position: 834362-835417 (Clockwise)

Preceding gene: 126696303

Following gene: 126696307

Centisome position: 50.82

GC content: 31.16

Gene sequence:

>1056_bases
ATGAATGTTGCAATAGTAGGTGCTACAGGTTACGGCGGTATTCAAGCGGTAAATCTTTTAAAGAAAAATAAAAATTACAA
AATTTCATTTTTAGGAGGTAATAAAACATCTGGATTAAAATGGAATGATAATTTTCCTTTTATTTATCTTGATAATGATC
CTTATATAGAAGAAATTTCAGTTGATAATATTTCAAAAAATGCTGATGTTGCTTTGCTTTGCTTACCAAATGGCTTATCT
TCAACATTGACAAGGAAATTATTAGATAAAGGACTTAAAGTTATTGATTTATCTGCTGATTATAGATATAAGTCTTTAGA
TGAATGGAAAAAAGTATATTCCAAAGAAGCTGCTATTTATAAAAGGAATGATGATGATTTATGTAAAGAAGCAGTTTACG
GTCTTCCTGAAATAAATAAAGAAGCCATTTCAAAAGGAAGATTAATTGCCTGTCCAGGATGTTATCCAACATCTGCTCTT
ATTCCATTGGCTCCTTATCTCTCTCAAGGAATTATTGAAAATGAAGGTATAGTTATTGACTCTAAAAGCGGAACTTCTGG
AGGTGGTCGAGAACCAAACCAAAAGCTACTCTTATCAGAATGTGGAGAAGGTCTGTCAGCATATGGATTGATAAACCATA
GACATACCTCAGAGATCGAGCAAGTGGCATCATTAATTTCTGGAACTAAAATTGAACTGCTTTTTACACCTCATTTAGTC
CCAATCTCAAGGGGTATGCATTCGACTATATATGGGAGATTAAGAGATCCAGGATTAACTTCTGATGACTGCAGGATTCT
TCTGGATAATTATTATAGAAATTTTAAAAATATTAAAGTCTTACCTGTAGATACATTCCCATCAACAAAATGGGTTAAAA
ATACAAACCAAATATTACTTTCTGTTAAAGTTGATAATCGAAATGGAAGAATAATTATATTGTCTGTAATTGATAATTTG
TTAAAAGGTCAGACTGGGCAGGCAATTCAAAATTTAAATATTATGAGTGGATTTTCAATGGATGAAGGTCTTGATTTAAC
TAATAATTTTCCATAA

Upstream 100 bases:

>100_bases
TGTTTCTTTCATTATTCCTATCAATATATAAAAATAGTGTTTTAGTTACCCTAAATTCAACACTTATTAATCCTATCTCA
AAGTCTGCCAATTCAAAGAA

Downstream 100 bases:

>100_bases
AGTTACTTCTTATCAAAAAACCAGCAAGAGAGATTGAGTGAGGTAAAATTTTATGTTCAAGCATTTGTATTCTTTTGGAA
AGTGATTCAATATCATCATC

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MNVAIVGATGYGGIQAVNLLKKNKNYKISFLGGNKTSGLKWNDNFPFIYLDNDPYIEEISVDNISKNADVALLCLPNGLS
STLTRKLLDKGLKVIDLSADYRYKSLDEWKKVYSKEAAIYKRNDDDLCKEAVYGLPEINKEAISKGRLIACPGCYPTSAL
IPLAPYLSQGIIENEGIVIDSKSGTSGGGREPNQKLLLSECGEGLSAYGLINHRHTSEIEQVASLISGTKIELLFTPHLV
PISRGMHSTIYGRLRDPGLTSDDCRILLDNYYRNFKNIKVLPVDTFPSTKWVKNTNQILLSVKVDNRNGRIIILSVIDNL
LKGQTGQAIQNLNIMSGFSMDEGLDLTNNFP

Sequences:

>Translated_351_residues
MNVAIVGATGYGGIQAVNLLKKNKNYKISFLGGNKTSGLKWNDNFPFIYLDNDPYIEEISVDNISKNADVALLCLPNGLS
STLTRKLLDKGLKVIDLSADYRYKSLDEWKKVYSKEAAIYKRNDDDLCKEAVYGLPEINKEAISKGRLIACPGCYPTSAL
IPLAPYLSQGIIENEGIVIDSKSGTSGGGREPNQKLLLSECGEGLSAYGLINHRHTSEIEQVASLISGTKIELLFTPHLV
PISRGMHSTIYGRLRDPGLTSDDCRILLDNYYRNFKNIKVLPVDTFPSTKWVKNTNQILLSVKVDNRNGRIIILSVIDNL
LKGQTGQAIQNLNIMSGFSMDEGLDLTNNFP
>Mature_351_residues
MNVAIVGATGYGGIQAVNLLKKNKNYKISFLGGNKTSGLKWNDNFPFIYLDNDPYIEEISVDNISKNADVALLCLPNGLS
STLTRKLLDKGLKVIDLSADYRYKSLDEWKKVYSKEAAIYKRNDDDLCKEAVYGLPEINKEAISKGRLIACPGCYPTSAL
IPLAPYLSQGIIENEGIVIDSKSGTSGGGREPNQKLLLSECGEGLSAYGLINHRHTSEIEQVASLISGTKIELLFTPHLV
PISRGMHSTIYGRLRDPGLTSDDCRILLDNYYRNFKNIKVLPVDTFPSTKWVKNTNQILLSVKVDNRNGRIIILSVIDNL
LKGQTGQAIQNLNIMSGFSMDEGLDLTNNFP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=349, Percent_Identity=30.0859598853868, Blast_Score=129, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6320913, Length=351, Percent_Identity=27.3504273504274, Blast_Score=109, Evalue=8e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_PROM0 (A3PCW5)

Other databases:

- EMBL:   CP000576
- RefSeq:   YP_001091191.1
- ProteinModelPortal:   A3PCW5
- SMR:   A3PCW5
- STRING:   A3PCW5
- GeneID:   4911690
- GenomeReviews:   CP000576_GR
- KEGG:   pmg:P9301_09671
- eggNOG:   COG0002
- HOGENOM:   HBG294213
- OMA:   GCFPTAS
- ProtClustDB:   PRK00436
- BioCyc:   PMAR167546:P9301ORF_0986-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 38737; Mature: 38737

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 154-154

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVAIVGATGYGGIQAVNLLKKNKNYKISFLGGNKTSGLKWNDNFPFIYLDNDPYIEEIS
CCEEEEEECCCCHHHHHHHHHCCCCEEEEEECCCCCCCCEECCCCCEEEECCCCCEEEEE
VDNISKNADVALLCLPNGLSSTLTRKLLDKGLKVIDLSADYRYKSLDEWKKVYSKEAAIY
CCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHCCCEEE
KRNDDDLCKEAVYGLPEINKEAISKGRLIACPGCYPTSALIPLAPYLSQGIIENEGIVID
ECCCHHHHHHHHHCCCCCCHHHHCCCCEEECCCCCCCCHHHHHHHHHHCCCCCCCCEEEE
SKSGTSGGGREPNQKLLLSECGEGLSAYGLINHRHTSEIEQVASLISGTKIELLFTPHLV
CCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCEE
PISRGMHSTIYGRLRDPGLTSDDCRILLDNYYRNFKNIKVLPVDTFPSTKWVKNTNQILL
EHHCCCCHHHHHEECCCCCCCCCCEEHHHHHHCCCCCEEEEEECCCCCCCEECCCCEEEE
SVKVDNRNGRIIILSVIDNLLKGQTGQAIQNLNIMSGFSMDEGLDLTNNFP
EEEEECCCCCEEEHHHHHHHHCCCCCCHHHCCEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MNVAIVGATGYGGIQAVNLLKKNKNYKISFLGGNKTSGLKWNDNFPFIYLDNDPYIEEIS
CCEEEEEECCCCHHHHHHHHHCCCCEEEEEECCCCCCCCEECCCCCEEEECCCCCEEEEE
VDNISKNADVALLCLPNGLSSTLTRKLLDKGLKVIDLSADYRYKSLDEWKKVYSKEAAIY
CCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHCCCEEE
KRNDDDLCKEAVYGLPEINKEAISKGRLIACPGCYPTSALIPLAPYLSQGIIENEGIVID
ECCCHHHHHHHHHCCCCCCHHHHCCCCEEECCCCCCCCHHHHHHHHHHCCCCCCCCEEEE
SKSGTSGGGREPNQKLLLSECGEGLSAYGLINHRHTSEIEQVASLISGTKIELLFTPHLV
CCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCEE
PISRGMHSTIYGRLRDPGLTSDDCRILLDNYYRNFKNIKVLPVDTFPSTKWVKNTNQILL
EHHCCCCHHHHHEECCCCCCCCCCEEHHHHHHCCCCCEEEEEECCCCCCCEECCCCEEEE
SVKVDNRNGRIIILSVIDNLLKGQTGQAIQNLNIMSGFSMDEGLDLTNNFP
EEEEECCCCCEEEHHHHHHHHCCCCCCHHHCCEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA