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The map label for this gene is csgA [H]

Identifier: 126696093

GI number: 126696093

Start: 664086

End: 664751

Strand: Direct

Name: csgA [H]

Synonym: P9301_07551

Alternate gene names: 126696093

Gene position: 664086-664751 (Clockwise)

Preceding gene: 126696083

Following gene: 126696100

Centisome position: 40.45

GC content: 32.28

Gene sequence:

>666_bases
ATGTCGACTTATCTAATTACAGGATCAAATAGAGGTATTGGATTAGAACTATGTAGGCAAATTCATAAGAGGGGAGATAA
TGTAATTGCAACGTGTAGGAAAGCTTCAAAAGAACTTAGGGATTTAGGTGTGAGAATTGAAGAGAATATAGAAATTTCTT
CTTATGAGTCGATAACAAACTTGTGTAAAAAACTATCTGGAGTTAATTTAGATTGCATAATTCATAATGCAGGAATTTAT
GAATTTAATTCTTTTGAAAACTTGGATAAAAAAAGTATTTTGCGGCAATTTGAAGTCAATGCATTGAGCCCAATATGTAT
GACTCAATCACTTAAACATTTTTTAAAAAGATCTTCTAAAGTTGCTTTTATCACAAGTAGAATGGGATCTATTGAAGATA
ATACATCTGGAAGTTCTTATGGTTACAGGATGTCTAAAGTCGCTTTGTCCATGGCAGCAAAATCACTTTCTGTAGATTTA
TCAAAAGAAGATATTTATGTAGCTATTTTGCATCCTGGGTTAGTGAGTACAAGAATGACTGGCTTTACAAGTAATGGAAT
TAGTCCTGAAGAATCAGCAAATGGCCTTTTAAAACGTATAGATTCTTTAAATAAAAATAACTCGGGTTCGTTTTGGCATG
CCAACGGAGAAGTTTTACCTTGGTAA

Upstream 100 bases:

>100_bases
TTTAAAAAATCTAGTAAGGAATTTTATAAATTTTTTCTTTTTCTAGTTCTTTTTCTTTATATATTTGAGTTTAGATTAAT
TTTTATTTTTTAGTTTAGAG

Downstream 100 bases:

>100_bases
AATCTATATTTTTATTTTTAAGAGGGTTATATTGTTAATTTGTTAAAAAACTTTTAAATTTTTAACGAATTTCTTTCTTT
GTTTAATTCTTTTAGTTATC

Product: short-chain dehydrogenase/reductase

Products: NA

Alternate protein names: C signal [H]

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MSTYLITGSNRGIGLELCRQIHKRGDNVIATCRKASKELRDLGVRIEENIEISSYESITNLCKKLSGVNLDCIIHNAGIY
EFNSFENLDKKSILRQFEVNALSPICMTQSLKHFLKRSSKVAFITSRMGSIEDNTSGSSYGYRMSKVALSMAAKSLSVDL
SKEDIYVAILHPGLVSTRMTGFTSNGISPEESANGLLKRIDSLNKNNSGSFWHANGEVLPW

Sequences:

>Translated_221_residues
MSTYLITGSNRGIGLELCRQIHKRGDNVIATCRKASKELRDLGVRIEENIEISSYESITNLCKKLSGVNLDCIIHNAGIY
EFNSFENLDKKSILRQFEVNALSPICMTQSLKHFLKRSSKVAFITSRMGSIEDNTSGSSYGYRMSKVALSMAAKSLSVDL
SKEDIYVAILHPGLVSTRMTGFTSNGISPEESANGLLKRIDSLNKNNSGSFWHANGEVLPW
>Mature_220_residues
STYLITGSNRGIGLELCRQIHKRGDNVIATCRKASKELRDLGVRIEENIEISSYESITNLCKKLSGVNLDCIIHNAGIYE
FNSFENLDKKSILRQFEVNALSPICMTQSLKHFLKRSSKVAFITSRMGSIEDNTSGSSYGYRMSKVALSMAAKSLSVDLS
KEDIYVAILHPGLVSTRMTGFTSNGISPEESANGLLKRIDSLNKNNSGSFWHANGEVLPW

Specific function: Cell-cell signaling protein required for fruiting body morphogenesis. Necessary for cellular aggregation, for spore differentiation, and for gene expression that is initiated after 6 hour of starvation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To yeast YKL071W [H]

Homologues:

Organism=Escherichia coli, GI1786701, Length=185, Percent_Identity=26.4864864864865, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17558996, Length=248, Percent_Identity=29.8387096774194, Blast_Score=100, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17559964, Length=248, Percent_Identity=34.6774193548387, Blast_Score=97, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17559962, Length=247, Percent_Identity=34.412955465587, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17558994, Length=242, Percent_Identity=31.404958677686, Blast_Score=89, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI193207563, Length=242, Percent_Identity=28.5123966942149, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI72001658, Length=244, Percent_Identity=34.0163934426229, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17542178, Length=240, Percent_Identity=31.25, Blast_Score=85, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17558992, Length=244, Percent_Identity=31.9672131147541, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17541382, Length=251, Percent_Identity=29.4820717131474, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17558990, Length=247, Percent_Identity=27.1255060728745, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17532177, Length=241, Percent_Identity=29.045643153527, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17558006, Length=204, Percent_Identity=30.3921568627451, Blast_Score=68, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322779, Length=245, Percent_Identity=29.7959183673469, Blast_Score=90, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24640547, Length=249, Percent_Identity=30.9236947791165, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24643142, Length=180, Percent_Identity=30, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 24461; Mature: 24330

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTYLITGSNRGIGLELCRQIHKRGDNVIATCRKASKELRDLGVRIEENIEISSYESITN
CCEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHH
LCKKLSGVNLDCIIHNAGIYEFNSFENLDKKSILRQFEVNALSPICMTQSLKHFLKRSSK
HHHHHCCCCEEEEEECCCCEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
VAFITSRMGSIEDNTSGSSYGYRMSKVALSMAAKSLSVDLSKEDIYVAILHPGLVSTRMT
EEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEECCCCEEEEEECCCHHHHHHC
GFTSNGISPEESANGLLKRIDSLNKNNSGSFWHANGEVLPW
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCCC
>Mature Secondary Structure 
STYLITGSNRGIGLELCRQIHKRGDNVIATCRKASKELRDLGVRIEENIEISSYESITN
CEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHH
LCKKLSGVNLDCIIHNAGIYEFNSFENLDKKSILRQFEVNALSPICMTQSLKHFLKRSSK
HHHHHCCCCEEEEEECCCCEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
VAFITSRMGSIEDNTSGSSYGYRMSKVALSMAAKSLSVDLSKEDIYVAILHPGLVSTRMT
EEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEECCCCEEEEEECCCHHHHHHC
GFTSNGISPEESANGLLKRIDSLNKNNSGSFWHANGEVLPW
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2152896; 2107980; 2118510; 1372277 [H]