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The map label for this gene is pilQ [H]

Identifier: 126696034

GI number: 126696034

Start: 619318

End: 621036

Strand: Direct

Name: pilQ [H]

Synonym: P9301_06961

Alternate gene names: 126696034

Gene position: 619318-621036 (Clockwise)

Preceding gene: 126696033

Following gene: 126696040

Centisome position: 37.72

GC content: 32.23

Gene sequence:

>1719_bases
TTGCGTATTAATAGAAAGTCTCTTAAAAGATCGTTTTCGCTATTTGCACTTACTTCTTTATTAAGTGCTAGCGCAAATTC
TGCGGAAAATGTTTCTTTTAATAAATTTAATCCCAAGAAAATTGTCACTCAAAATATTCTTCTTAATTACCCTAAAGAAT
TTTTAAATGAGGATAAACTTTTTCAAAATCAAAATTATTTATTGTCCTCTTTAATTTCTAACCCAAATTTATTAGAAATT
GAAGGACCCTCTGTCTCATTAGTATTTAAGCAAGCTAAAGCAAAAGCAATTTTTGAATATCTCGCTGAAATAGGAAATTA
TGGTTTTGTATGGGTTAAAAATAGTCCTAATAAAGAGAATGATGTAGATAATCAGAGATTAATTTCGATGACCTTAAACG
ATGTAAGTTATAAAAAAGCTATTAATTCATTGTTATTGGCAAGTGGTTTGCAAGCAAAATTGCATAATAATATTCTTTAT
GTAGGCCCTAACGTAAGAAATACTGTTTTTGATACAAGAAGCACTGATGTTTATCAGTTGAATCAGATAAGTGCCAGCTC
AGCTGCTGATTATTTAGCAAATTTAGGAGCTAGTGTTACAAAAACATTCACGATTACAACATCTGTTACTTCTGGAGCCT
CACAATCTCAGGCAGTTCAAGGAGCCTCAACATCTTCTACTACTACTGATCAATCAGAAACATCAGTTAAAGTTTATGGC
GCAACTATTGGCCCATTAGTAGGCTTAATTGCGACTACTGATGAGCGACTTCAAACAGTAACAATGGTTGGCGAAAAATA
TCTTATTGATTTAGCTAATGGATTTTTACAGAAATTAGACATTAAACAAAAACAAGTTGCATTAAGCGTCAAAGTCCTTG
ATGTAAATATGTCAGATAAGAATTCATCCATGAAAGATTATGGAGGTAAATTAGACGATGCATTTATAATTGGTAGCCAA
GGAAAAATTAAATCAGCATTTGGAAGCTTTTTACCAGTTTTCCCTGAAGGAAATTCTACAGATGCAACCACCAATCCAGG
AATTAACTCAAGTCAAAGAACAACTAATTTTGATAACAAATCTTTTTTTGGTTTGTTAGAAGCAAGTATTGAAAATGGAA
CTACAAAGGTTTTAGCAAGTCCAACTCTTTTACTAAGTGAATCATCTGGTTCGGCAGGAGATGGAAGTAGTATAGGTCGA
AAGGTTGGCAATGAGGGTTTTGTTGAGATTGGGGATAAGGTTCCTGTAGATGCAACAAAAGGCGATGGTGGTTCTTGTAC
TTATAGTTTTGAAACTGTGGGAGTAAAATTAGGTGCGAAAATCCTAGGTATTGATCAAAATGATTATGTTACTTTTACAA
TGACACCTATTGTTACTGGAATTTCAGGTAGTTTTAATATTGTTGGATGTGGTTCAGTTTCAAAGATTAATAATAGGAGA
CTTGATACTGGTGCTATACGGATAAAAGATGGCGAAACATTAGTTCTTACTGGTGTTATCCAAGAAACTGATATAGATAC
AACTTACAAATTACCATTACTTGGAGATTTACCTTTATTGGGGGGTTTATTTAGATCAAAACAAGCTTCAAAAGATAAAA
GAGAGCTCATTATTTTAGTAACTCCAAAAGTTCTGGAAGACAAATCATCCAATATTGCAGATTATAATCTCGAATTTAAA
AACAAAGATGCTACAAATTTAATTAATCAAATTAAGTAA

Upstream 100 bases:

>100_bases
TATTATTTAAATCTTTTAATAGTTACCAACTAAGAAGAACAAATTTTTTTGTTGATTTTAACCTATGTTGCTATTATTAT
TAGTAATTTAAGAAAATATC

Downstream 100 bases:

>100_bases
CGAAAATTAATTAATCTATTTGATATGGACGCAGAAGGATTCAGGACCTTTTGAAAGAGATCCTAACCAGTCATTGGCAA
AAATATTTTTTGAACTCTCG

Product: Type II secretory pathway component PulD-like protein

Products: NA

Alternate protein names: Outer membrane protein omc [H]

Number of amino acids: Translated: 572; Mature: 572

Protein sequence:

>572_residues
MRINRKSLKRSFSLFALTSLLSASANSAENVSFNKFNPKKIVTQNILLNYPKEFLNEDKLFQNQNYLLSSLISNPNLLEI
EGPSVSLVFKQAKAKAIFEYLAEIGNYGFVWVKNSPNKENDVDNQRLISMTLNDVSYKKAINSLLLASGLQAKLHNNILY
VGPNVRNTVFDTRSTDVYQLNQISASSAADYLANLGASVTKTFTITTSVTSGASQSQAVQGASTSSTTTDQSETSVKVYG
ATIGPLVGLIATTDERLQTVTMVGEKYLIDLANGFLQKLDIKQKQVALSVKVLDVNMSDKNSSMKDYGGKLDDAFIIGSQ
GKIKSAFGSFLPVFPEGNSTDATTNPGINSSQRTTNFDNKSFFGLLEASIENGTTKVLASPTLLLSESSGSAGDGSSIGR
KVGNEGFVEIGDKVPVDATKGDGGSCTYSFETVGVKLGAKILGIDQNDYVTFTMTPIVTGISGSFNIVGCGSVSKINNRR
LDTGAIRIKDGETLVLTGVIQETDIDTTYKLPLLGDLPLLGGLFRSKQASKDKRELIILVTPKVLEDKSSNIADYNLEFK
NKDATNLINQIK

Sequences:

>Translated_572_residues
MRINRKSLKRSFSLFALTSLLSASANSAENVSFNKFNPKKIVTQNILLNYPKEFLNEDKLFQNQNYLLSSLISNPNLLEI
EGPSVSLVFKQAKAKAIFEYLAEIGNYGFVWVKNSPNKENDVDNQRLISMTLNDVSYKKAINSLLLASGLQAKLHNNILY
VGPNVRNTVFDTRSTDVYQLNQISASSAADYLANLGASVTKTFTITTSVTSGASQSQAVQGASTSSTTTDQSETSVKVYG
ATIGPLVGLIATTDERLQTVTMVGEKYLIDLANGFLQKLDIKQKQVALSVKVLDVNMSDKNSSMKDYGGKLDDAFIIGSQ
GKIKSAFGSFLPVFPEGNSTDATTNPGINSSQRTTNFDNKSFFGLLEASIENGTTKVLASPTLLLSESSGSAGDGSSIGR
KVGNEGFVEIGDKVPVDATKGDGGSCTYSFETVGVKLGAKILGIDQNDYVTFTMTPIVTGISGSFNIVGCGSVSKINNRR
LDTGAIRIKDGETLVLTGVIQETDIDTTYKLPLLGDLPLLGGLFRSKQASKDKRELIILVTPKVLEDKSSNIADYNLEFK
NKDATNLINQIK
>Mature_572_residues
MRINRKSLKRSFSLFALTSLLSASANSAENVSFNKFNPKKIVTQNILLNYPKEFLNEDKLFQNQNYLLSSLISNPNLLEI
EGPSVSLVFKQAKAKAIFEYLAEIGNYGFVWVKNSPNKENDVDNQRLISMTLNDVSYKKAINSLLLASGLQAKLHNNILY
VGPNVRNTVFDTRSTDVYQLNQISASSAADYLANLGASVTKTFTITTSVTSGASQSQAVQGASTSSTTTDQSETSVKVYG
ATIGPLVGLIATTDERLQTVTMVGEKYLIDLANGFLQKLDIKQKQVALSVKVLDVNMSDKNSSMKDYGGKLDDAFIIGSQ
GKIKSAFGSFLPVFPEGNSTDATTNPGINSSQRTTNFDNKSFFGLLEASIENGTTKVLASPTLLLSESSGSAGDGSSIGR
KVGNEGFVEIGDKVPVDATKGDGGSCTYSFETVGVKLGAKILGIDQNDYVTFTMTPIVTGISGSFNIVGCGSVSKINNRR
LDTGAIRIKDGETLVLTGVIQETDIDTTYKLPLLGDLPLLGGLFRSKQASKDKRELIILVTPKVLEDKSSNIADYNLEFK
NKDATNLINQIK

Specific function: Required for type IV pilus biogenesis and competence. Could function as a pore for exit of the pilus but also as a channel for entry of heme and antimicrobial agents and uptake of transforming DNA [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane. Note=Associated to the membrane through its C-terminus [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=425, Percent_Identity=22.8235294117647, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI87082242, Length=329, Percent_Identity=23.4042553191489, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 61662; Mature: 61662

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRINRKSLKRSFSLFALTSLLSASANSAENVSFNKFNPKKIVTQNILLNYPKEFLNEDKL
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCHHHHHHHHHHCCCHHHCCCHHH
FQNQNYLLSSLISNPNLLEIEGPSVSLVFKQAKAKAIFEYLAEIGNYGFVWVKNSPNKEN
HCCCHHHHHHHHCCCCEEEECCCCEEEEEHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
DVDNQRLISMTLNDVSYKKAINSLLLASGLQAKLHNNILYVGPNVRNTVFDTRSTDVYQL
CCCCCEEEEEEECHHHHHHHHHHHHHHCCCHHHHHCCEEEECCCCCCCEECCCCCCEEEE
NQISASSAADYLANLGASVTKTFTITTSVTSGASQSQAVQGASTSSTTTDQSETSVKVYG
ECCCHHHHHHHHHHCCCCEEEEEEEEEEECCCCCHHHHHCCCCCCCCCCCCCCCEEEEEE
ATIGPLVGLIATTDERLQTVTMVGEKYLIDLANGFLQKLDIKQKQVALSVKVLDVNMSDK
CHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCCC
NSSMKDYGGKLDDAFIIGSQGKIKSAFGSFLPVFPEGNSTDATTNPGINSSQRTTNFDNK
CCCHHHCCCCCCCEEEECCCCCHHHHHHCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCC
SFFGLLEASIENGTTKVLASPTLLLSESSGSAGDGSSIGRKVGNEGFVEIGDKVPVDATK
HHHEEEEHHHCCCCEEEEECCEEEEECCCCCCCCCHHHHHHCCCCCCEEECCCCCCCCCC
GDGGSCTYSFETVGVKLGAKILGIDQNDYVTFTMTPIVTGISGSFNIVGCGSVSKINNRR
CCCCEEEEEEEEEEEEECCEEEEECCCCEEEEEEEEEEECCCCCEEEEECCCCHHCCCCE
LDTGAIRIKDGETLVLTGVIQETDIDTTYKLPLLGDLPLLGGLFRSKQASKDKRELIILV
ECCCEEEEECCCEEEEEEEEEECCCCCEEECCCCCCCHHHHHHHHHHHCCCCCCCEEEEE
TPKVLEDKSSNIADYNLEFKNKDATNLINQIK
CCHHHCCCCCCEEEEEEEECCCCHHHHHHHCC
>Mature Secondary Structure
MRINRKSLKRSFSLFALTSLLSASANSAENVSFNKFNPKKIVTQNILLNYPKEFLNEDKL
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCHHHHHHHHHHCCCHHHCCCHHH
FQNQNYLLSSLISNPNLLEIEGPSVSLVFKQAKAKAIFEYLAEIGNYGFVWVKNSPNKEN
HCCCHHHHHHHHCCCCEEEECCCCEEEEEHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
DVDNQRLISMTLNDVSYKKAINSLLLASGLQAKLHNNILYVGPNVRNTVFDTRSTDVYQL
CCCCCEEEEEEECHHHHHHHHHHHHHHCCCHHHHHCCEEEECCCCCCCEECCCCCCEEEE
NQISASSAADYLANLGASVTKTFTITTSVTSGASQSQAVQGASTSSTTTDQSETSVKVYG
ECCCHHHHHHHHHHCCCCEEEEEEEEEEECCCCCHHHHHCCCCCCCCCCCCCCCEEEEEE
ATIGPLVGLIATTDERLQTVTMVGEKYLIDLANGFLQKLDIKQKQVALSVKVLDVNMSDK
CHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCCC
NSSMKDYGGKLDDAFIIGSQGKIKSAFGSFLPVFPEGNSTDATTNPGINSSQRTTNFDNK
CCCHHHCCCCCCCEEEECCCCCHHHHHHCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCC
SFFGLLEASIENGTTKVLASPTLLLSESSGSAGDGSSIGRKVGNEGFVEIGDKVPVDATK
HHHEEEEHHHCCCCEEEEECCEEEEECCCCCCCCCHHHHHHCCCCCCEEECCCCCCCCCC
GDGGSCTYSFETVGVKLGAKILGIDQNDYVTFTMTPIVTGISGSFNIVGCGSVSKINNRR
CCCCEEEEEEEEEEEEECCEEEEECCCCEEEEEEEEEEECCCCCEEEEECCCCHHCCCCE
LDTGAIRIKDGETLVLTGVIQETDIDTTYKLPLLGDLPLLGGLFRSKQASKDKRELIILV
ECCCEEEEECCCEEEEEEEEEECCCCCEEECCCCCCCHHHHHHHHHHHCCCCCCCEEEEE
TPKVLEDKSSNIADYNLEFKNKDATNLINQIK
CCHHHCCCCCCEEEEEEEECCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA