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The map label for this gene is accA

Identifier: 126695898

GI number: 126695898

Start: 489984

End: 490991

Strand: Direct

Name: accA

Synonym: P9301_05601

Alternate gene names: 126695898

Gene position: 489984-490991 (Clockwise)

Preceding gene: 126695897

Following gene: 126695899

Centisome position: 29.84

GC content: 39.68

Gene sequence:

>1008_bases
ATGGCTAAACGTTACCTCCTCGATTTTGAAAAGCCTCTTGTTGAACTTGAGAAGCAGATAGAGCAAATTAAAGAACTAGC
TCGAGATTCGGAGGTAGATGTTAGTCAACAGCTTCTACAGCTTGAAACCCTAGCGGCTAGAAGAAGAGAAGAAATCTTTA
AATCTCTCACACCTGCTCAAAAGATTCAGGTAGCTAGACATCCTCAAAGGCCAAGTACTTTGGACTTTGTTCAAATGTTT
TGTGATGATTGGATCGAATTACATGGAGACAGAAATGGTGGCGATGATATGGCACTAATTGGGGGGATAGGTTCGATAAA
TAATAGACCAGTATTGATGTTAGGACATCAGAAAGGAAGGGACACAAAAGAAAATGTAGTAAGAAACTTTGGGATGGCAA
AACCAGGAGGTTACAGAAAAGCTCTTAGATTAATGCAGCATGCTAATAGATTCTCTTTGCCAATTCTTACATTTATTGAT
ACTCCTGGAGCCTATGCTGGTTTAAAAGCTGAAGAACATGGTCAAGGGGAAGCGATTGCAAGAAACCTTCGAGAGATGTT
TGGATTGAAAGTCCCAATTGTGGCTACTGTCATTGGAGAAGGAGGTTCAGGAGGCGCACTTGGAATAGGTGTTGCAGATA
GGTTACTAATGTTCGAACACAGTGTTTACACAGTTGCTAGTCCTGAAGCATGTGCATCAATTTTGTGGAGAGATGCTGCG
AAGGCACCAGAAGCTGCATCAGCACTTAAAATTACAGGTAAAGACTTACTCAAATTGGGGATTATAGATGAGGTATTACC
AGAACCTTCTGGTGGGAATAATTGGGCTCCTTTAGATGCTGGCAACACACTAAAAGAGGCTATTGAGAAACACCTTAACG
CTTTACTGAAAATGCCTGAAGACGAATTAATTGAGGAAAGATACAAAAAGTTTAGGGTTTTAGGTAAATTTATCGAAGCA
AATAATATTGAAGAGATTTATAGTGAAATCCCCCAAAAAACTGAATAA

Upstream 100 bases:

>100_bases
TCCCTTGAAAAGATGGAATTTATTGGAGCAGCTTCTTTAAAGCATGGTTTTTCAGCAATTGGACTTGATAAACAGCCTAA
AGTATTAACTGTCTAAAATT

Downstream 100 bases:

>100_bases
ATTGAAACTAGCTTTTATAACGGGTGCTACGAAAGGTATTGGTAAATCTACCGCAATTACTTTTGCTAATGCTGGCTGGG
ATTTAATTTTACTTTCCAGG

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MAKRYLLDFEKPLVELEKQIEQIKELARDSEVDVSQQLLQLETLAARRREEIFKSLTPAQKIQVARHPQRPSTLDFVQMF
CDDWIELHGDRNGGDDMALIGGIGSINNRPVLMLGHQKGRDTKENVVRNFGMAKPGGYRKALRLMQHANRFSLPILTFID
TPGAYAGLKAEEHGQGEAIARNLREMFGLKVPIVATVIGEGGSGGALGIGVADRLLMFEHSVYTVASPEACASILWRDAA
KAPEAASALKITGKDLLKLGIIDEVLPEPSGGNNWAPLDAGNTLKEAIEKHLNALLKMPEDELIEERYKKFRVLGKFIEA
NNIEEIYSEIPQKTE

Sequences:

>Translated_335_residues
MAKRYLLDFEKPLVELEKQIEQIKELARDSEVDVSQQLLQLETLAARRREEIFKSLTPAQKIQVARHPQRPSTLDFVQMF
CDDWIELHGDRNGGDDMALIGGIGSINNRPVLMLGHQKGRDTKENVVRNFGMAKPGGYRKALRLMQHANRFSLPILTFID
TPGAYAGLKAEEHGQGEAIARNLREMFGLKVPIVATVIGEGGSGGALGIGVADRLLMFEHSVYTVASPEACASILWRDAA
KAPEAASALKITGKDLLKLGIIDEVLPEPSGGNNWAPLDAGNTLKEAIEKHLNALLKMPEDELIEERYKKFRVLGKFIEA
NNIEEIYSEIPQKTE
>Mature_334_residues
AKRYLLDFEKPLVELEKQIEQIKELARDSEVDVSQQLLQLETLAARRREEIFKSLTPAQKIQVARHPQRPSTLDFVQMFC
DDWIELHGDRNGGDDMALIGGIGSINNRPVLMLGHQKGRDTKENVVRNFGMAKPGGYRKALRLMQHANRFSLPILTFIDT
PGAYAGLKAEEHGQGEAIARNLREMFGLKVPIVATVIGEGGSGGALGIGVADRLLMFEHSVYTVASPEACASILWRDAAK
APEAASALKITGKDLLKLGIIDEVLPEPSGGNNWAPLDAGNTLKEAIEKHLNALLKMPEDELIEERYKKFRVLGKFIEAN
NIEEIYSEIPQKTE

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=313, Percent_Identity=50.1597444089457, Blast_Score=313, Evalue=1e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_PROM0 (A3PBQ8)

Other databases:

- EMBL:   CP000576
- RefSeq:   YP_001090784.1
- ProteinModelPortal:   A3PBQ8
- SMR:   A3PBQ8
- STRING:   A3PBQ8
- GeneID:   4912083
- GenomeReviews:   CP000576_GR
- KEGG:   pmg:P9301_05601
- eggNOG:   COG0825
- HOGENOM:   HBG286557
- OMA:   QLTKDIY
- ProtClustDB:   PRK05724
- BioCyc:   PMAR167546:P9301ORF_0573-MONOMER
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 37160; Mature: 37029

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKRYLLDFEKPLVELEKQIEQIKELARDSEVDVSQQLLQLETLAARRREEIFKSLTPAQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHH
KIQVARHPQRPSTLDFVQMFCDDWIELHGDRNGGDDMALIGGIGSINNRPVLMLGHQKGR
HHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCEEEECCCCCC
DTKENVVRNFGMAKPGGYRKALRLMQHANRFSLPILTFIDTPGAYAGLKAEEHGQGEAIA
CHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHH
RNLREMFGLKVPIVATVIGEGGSGGALGIGVADRLLMFEHSVYTVASPEACASILWRDAA
HHHHHHHCCCCCCCEEEECCCCCCCEEHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHC
KAPEAASALKITGKDLLKLGIIDEVLPEPSGGNNWAPLDAGNTLKEAIEKHLNALLKMPE
CCCCHHHHHEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCH
DELIEERYKKFRVLGKFIEANNIEEIYSEIPQKTE
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCC
>Mature Secondary Structure 
AKRYLLDFEKPLVELEKQIEQIKELARDSEVDVSQQLLQLETLAARRREEIFKSLTPAQ
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHH
KIQVARHPQRPSTLDFVQMFCDDWIELHGDRNGGDDMALIGGIGSINNRPVLMLGHQKGR
HHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCEEEECCCCCC
DTKENVVRNFGMAKPGGYRKALRLMQHANRFSLPILTFIDTPGAYAGLKAEEHGQGEAIA
CHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHH
RNLREMFGLKVPIVATVIGEGGSGGALGIGVADRLLMFEHSVYTVASPEACASILWRDAA
HHHHHHHCCCCCCCEEEECCCCCCCEEHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHC
KAPEAASALKITGKDLLKLGIIDEVLPEPSGGNNWAPLDAGNTLKEAIEKHLNALLKMPE
CCCCHHHHHEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCH
DELIEERYKKFRVLGKFIEANNIEEIYSEIPQKTE
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA