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The map label for this gene is lepB2 [H]

Identifier: 126695878

GI number: 126695878

Start: 469323

End: 469982

Strand: Direct

Name: lepB2 [H]

Synonym: P9301_05401

Alternate gene names: 126695878

Gene position: 469323-469982 (Clockwise)

Preceding gene: 126695877

Following gene: 126695880

Centisome position: 28.58

GC content: 30.45

Gene sequence:

>660_bases
ATGACTGGTTCCATAAAAAGTTTTTTAAAAGAATGGGGTCTACTAATTTTATTAACTTTTTTTGTTTCTTCTTGTAGATC
ATTTTTTGCAGAACCACGTTATATCCCTTCTGGTTCAATGCTCCCAGAATTACAAATAAATGATAGGTTAATTATTGAAA
AATTTTCGCTAAGAAACTCTTTACCAAAAAGAGGAGATATTGTTGTTTTTAACTCACCTTACTCGTTTGACAAAAAATTA
ATTTCATCAAGAGCTAAGCCCTTACCAAAAAAAAGATATTGTTTTTTTATGAGTTTTCCCCCAATGTCGTTTATTCCTGG
TTTAAGGGATCAAGCTTGCGATGCCTATATTAAAAGAGTGGTAGCAATTCCAGGAGAAATTGTAAGTGTAAACTCTAATG
GTGAATTAATAATAAATAATAAATTAATTCCTGAACCCTATGTCTCTTATAAGTGCTCATTATCCCTTTTTAATAAATGT
GGTGAATTTGAAAATATAAAGGTGCCAGAAGATCATTTTTTAGTTTTAGGTGATAATAGGGCAAATAGCTGGGATGGAAG
ATATTGGCCTGGAAGTAAATTTCTTCATAAAAAAGAGATAATTGGTAAAGCATATTTCAGATTTTGGCCTCTTAATCAAG
TTGGCTTTTTCAGTAAATAA

Upstream 100 bases:

>100_bases
TTTTAATTTACGAAGGAAAAAAAGTAATTTTAGGTTTTAACGAAATTGAATATGCAAAAGATTTTATATAAGTTTAGAAA
ATCAAGCTTTTATTAATCCT

Downstream 100 bases:

>100_bases
AGCCTTTTTTCTGACTCTGACTTCATCAAAATAAATTTTTAACAAGGCTTATTTTAAAGTGCCCCTGAAGCAGTTGAATC
AAGTATTCCCCCTAGGTGTG

Product: Signal peptidase I

Products: NA

Alternate protein names: SPase I-2; Leader peptidase I-2 [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MTGSIKSFLKEWGLLILLTFFVSSCRSFFAEPRYIPSGSMLPELQINDRLIIEKFSLRNSLPKRGDIVVFNSPYSFDKKL
ISSRAKPLPKKRYCFFMSFPPMSFIPGLRDQACDAYIKRVVAIPGEIVSVNSNGELIINNKLIPEPYVSYKCSLSLFNKC
GEFENIKVPEDHFLVLGDNRANSWDGRYWPGSKFLHKKEIIGKAYFRFWPLNQVGFFSK

Sequences:

>Translated_219_residues
MTGSIKSFLKEWGLLILLTFFVSSCRSFFAEPRYIPSGSMLPELQINDRLIIEKFSLRNSLPKRGDIVVFNSPYSFDKKL
ISSRAKPLPKKRYCFFMSFPPMSFIPGLRDQACDAYIKRVVAIPGEIVSVNSNGELIINNKLIPEPYVSYKCSLSLFNKC
GEFENIKVPEDHFLVLGDNRANSWDGRYWPGSKFLHKKEIIGKAYFRFWPLNQVGFFSK
>Mature_218_residues
TGSIKSFLKEWGLLILLTFFVSSCRSFFAEPRYIPSGSMLPELQINDRLIIEKFSLRNSLPKRGDIVVFNSPYSFDKKLI
SSRAKPLPKKRYCFFMSFPPMSFIPGLRDQACDAYIKRVVAIPGEIVSVNSNGELIINNKLIPEPYVSYKCSLSLFNKCG
EFENIKVPEDHFLVLGDNRANSWDGRYWPGSKFLHKKEIIGKAYFRFWPLNQVGFFSK

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 25233; Mature: 25102

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGSIKSFLKEWGLLILLTFFVSSCRSFFAEPRYIPSGSMLPELQINDRLIIEKFSLRNS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCEEEEEEHHHHCC
LPKRGDIVVFNSPYSFDKKLISSRAKPLPKKRYCFFMSFPPMSFIPGLRDQACDAYIKRV
CCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCEEEEEECCCHHHCCCCCHHHHHHHHHHH
VAIPGEIVSVNSNGELIINNKLIPEPYVSYKCSLSLFNKCGEFENIKVPEDHFLVLGDNR
HHCCCEEEEECCCCCEEECCCCCCCCCCCEEEHHHHHHHCCCCCCCCCCCCCEEEEECCC
ANSWDGRYWPGSKFLHKKEIIGKAYFRFWPLNQVGFFSK
CCCCCCCCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCC
>Mature Secondary Structure 
TGSIKSFLKEWGLLILLTFFVSSCRSFFAEPRYIPSGSMLPELQINDRLIIEKFSLRNS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCEEEEEEHHHHCC
LPKRGDIVVFNSPYSFDKKLISSRAKPLPKKRYCFFMSFPPMSFIPGLRDQACDAYIKRV
CCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCEEEEEECCCHHHCCCCCHHHHHHHHHHH
VAIPGEIVSVNSNGELIINNKLIPEPYVSYKCSLSLFNKCGEFENIKVPEDHFLVLGDNR
HHCCCEEEEECCCCCEEECCCCCCCCCCCEEEHHHHHHHCCCCCCCCCCCCCEEEEECCC
ANSWDGRYWPGSKFLHKKEIIGKAYFRFWPLNQVGFFSK
CCCCCCCCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]