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The map label for this gene is ndhI

Identifier: 126695517

GI number: 126695517

Start: 165223

End: 165849

Strand: Reverse

Name: ndhI

Synonym: P9301_01791

Alternate gene names: 126695517

Gene position: 165849-165223 (Counterclockwise)

Preceding gene: 126695518

Following gene: 126695516

Centisome position: 10.1

GC content: 32.7

Gene sequence:

>627_bases
ATGAAAAATTTCCTTCAACAAATTAATAGCTATATCAAAGAAGCATTTAATGCTGGCAAATATTTATATAATGGCTTTTC
AGTTACTTTTGATCATCTTCGAAGAAGACCTGTTACTGTCCAATATCCATATGAAAAATTAATACCCTCTGAAAGATATA
GAGGGAGAATACATTATGAATTTGATAAATGTATTGCTTGTGAAGTTTGCGTGAGAGTATGCCCTATAAATCTCCCAGTA
GTTGATTGGGTAATGAATAAAGAAACCAAAAAAAAGGAACTTAGAAATTATTCTATAGACTTTGGAGTTTGTATTTTTTG
CGGAAATTGTGTTGAATATTGTCCAACTAATTGTCTTTCAATGACCGAAGAGTATGAATTAGCTACTTTTGACAGACATA
ATCTAAATTTTGATAATGTTGCACTTGGAAGGTTACCTACAAACGTGACAACAGATCCTTCAGTAAAACCCCTAAGAGAA
CTTGCCTATCTTCCTAAAGGGGTCATGGACCCTCATGAAGTCCCAAGCTCAGATACTAGAGTTGGTAAATTACCAGAAGA
AGTTTATGATTGGATGAGATCAGAATCCAATGAAAAAAAAGATAAAGCTTCTAATCCAAACAATTAA

Upstream 100 bases:

>100_bases
AACTTGCTTTTCCGCAATTCTTTGGAGGTTAAACTTAAGTAAAAATACTTAAATTTAAATTTAATCCACTAAAATAAAAT
CACTGAGTAAATTCTTCAAA

Downstream 100 bases:

>100_bases
TTTCCATTAATTTATGTCCATCGCAATAACAACTCAAATTATTTGTTTTACAATTTTGTCTTTAGTGATTCTGATTGGAG
CACTAGGTGTTGTATTGCTA

Product: NADH dehydrogenase subunit I

Products: NAD+; ubiquinol

Alternate protein names: NAD(P)H dehydrogenase I subunit I; NDH-1 subunit I; NDH-I

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MKNFLQQINSYIKEAFNAGKYLYNGFSVTFDHLRRRPVTVQYPYEKLIPSERYRGRIHYEFDKCIACEVCVRVCPINLPV
VDWVMNKETKKKELRNYSIDFGVCIFCGNCVEYCPTNCLSMTEEYELATFDRHNLNFDNVALGRLPTNVTTDPSVKPLRE
LAYLPKGVMDPHEVPSSDTRVGKLPEEVYDWMRSESNEKKDKASNPNN

Sequences:

>Translated_208_residues
MKNFLQQINSYIKEAFNAGKYLYNGFSVTFDHLRRRPVTVQYPYEKLIPSERYRGRIHYEFDKCIACEVCVRVCPINLPV
VDWVMNKETKKKELRNYSIDFGVCIFCGNCVEYCPTNCLSMTEEYELATFDRHNLNFDNVALGRLPTNVTTDPSVKPLRE
LAYLPKGVMDPHEVPSSDTRVGKLPEEVYDWMRSESNEKKDKASNPNN
>Mature_208_residues
MKNFLQQINSYIKEAFNAGKYLYNGFSVTFDHLRRRPVTVQYPYEKLIPSERYRGRIHYEFDKCIACEVCVRVCPINLPV
VDWVMNKETKKKELRNYSIDFGVCIFCGNCVEYCPTNCLSMTEEYELATFDRHNLNFDNVALGRLPTNVTTDPSVKPLRE
LAYLPKGVMDPHEVPSSDTRVGKLPEEVYDWMRSESNEKKDKASNPNN

Specific function: NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone

COG id: COG1143

COG function: function code C; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)

Gene ontology:

Cell location: Cellular thylakoid membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains

Homologues:

Organism=Homo sapiens, GI4505371, Length=126, Percent_Identity=30.952380952381, Blast_Score=74, Evalue=8e-14,
Organism=Escherichia coli, GI1789075, Length=110, Percent_Identity=30.9090909090909, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1788617, Length=110, Percent_Identity=32.7272727272727, Blast_Score=65, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17555194, Length=126, Percent_Identity=30.952380952381, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI17864306, Length=126, Percent_Identity=31.7460317460317, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NDHI_PROM0 (A3PAM7)

Other databases:

- EMBL:   CP000576
- RefSeq:   YP_001090403.1
- ProteinModelPortal:   A3PAM7
- SMR:   A3PAM7
- STRING:   A3PAM7
- GeneID:   4912496
- GenomeReviews:   CP000576_GR
- KEGG:   pmg:P9301_01791
- eggNOG:   COG1143
- HOGENOM:   HBG724359
- OMA:   ELATFDR
- ProtClustDB:   PRK05888
- BioCyc:   PMAR167546:P9301ORF_0181-MONOMER
- HAMAP:   MF_01351
- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012285
- InterPro:   IPR004497
- InterPro:   IPR010226
- Gene3D:   G3DSA:1.10.1060.10
- TIGRFAMs:   TIGR00403
- TIGRFAMs:   TIGR01971

Pfam domain/function: PF00037 Fer4

EC number: 1.6.5.3

Molecular weight: Translated: 24214; Mature: 24214

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: PS00198 4FE4S_FER_1; PS51379 4FE4S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNFLQQINSYIKEAFNAGKYLYNGFSVTFDHLRRRPVTVQYPYEKLIPSERYRGRIHYE
CHHHHHHHHHHHHHHHHCCHHHHCCHHEEHHHHHCCCCEEECCHHHCCCCHHHCCCEEEH
FDKCIACEVCVRVCPINLPVVDWVMNKETKKKELRNYSIDFGVCIFCGNCVEYCPTNCLS
HHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHCCCCCHHHHHHHCCHHHHCCCHHHH
MTEEYELATFDRHNLNFDNVALGRLPTNVTTDPSVKPLRELAYLPKGVMDPHEVPSSDTR
HHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
VGKLPEEVYDWMRSESNEKKDKASNPNN
CCCCHHHHHHHHHCCCCCHHHCCCCCCC
>Mature Secondary Structure
MKNFLQQINSYIKEAFNAGKYLYNGFSVTFDHLRRRPVTVQYPYEKLIPSERYRGRIHYE
CHHHHHHHHHHHHHHHHCCHHHHCCHHEEHHHHHCCCCEEECCHHHCCCCHHHCCCEEEH
FDKCIACEVCVRVCPINLPVVDWVMNKETKKKELRNYSIDFGVCIFCGNCVEYCPTNCLS
HHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHCCCCCHHHHHHHCCHHHHCCCHHHH
MTEEYELATFDRHNLNFDNVALGRLPTNVTTDPSVKPLRELAYLPKGVMDPHEVPSSDTR
HHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
VGKLPEEVYDWMRSESNEKKDKASNPNN
CCCCHHHHHHHHHCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; H+; ubiquinone

Specific reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA