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The map label for this gene is dhsS

Identifier: 126695372

GI number: 126695372

Start: 32468

End: 33631

Strand: Reverse

Name: dhsS

Synonym: P9301_00341

Alternate gene names: NA

Gene position: 33631-32468 (Counterclockwise)

Preceding gene: 126695375

Following gene: 126695370

Centisome position: 2.05

GC content: 33.33

Gene sequence:

>1164_bases
GTGGCCATACAACAAAAATTATCATTGATGATTCCTGGACCCACACCAGTTCCAGAAAAAGTTTTACAAGCATTGAGTAA
GCATCCAATAGGCCATCGCAGCAAAGAATTCCAAGACCTCGTACAGAGTACTACTAAAAATTTACAGTGGCTTCATCAAA
CTCAAAATGATGTTCTAACAATTACTGGTAGTGGGACAGCCGCAATGGAGGCTGGAATAATAAATACCTTAAGTAGAGGA
GATAAAGTAATTTGTGGAGAAAATGGAAAATTTGGCGAAAGATGGGTAAAAGTTGCTAAAGAATTTGGTCTAGAAGTAAT
AAAAATTGATTCGGAATGGGGAATTCCGCTTGACCCAGAAGAATTTAGAAAAGTATTAGAGGAAGATAAACACAAAGAAA
TAAAGGCAGTTATTTTGACTCATTCTGAAACCTCAACAGGTGTCATTAATGATCTAGAAACTATAAGTTCATATATTCGT
AAACACAACACAGCTTTATCAATTGTTGACTGCGTTACAAGTCTTGGTGCTTGCAATGTACCAGTAGATGAATGGAAATT
AGATATAGTTGCTTCAGGTTCACAAAAGGGATATATGATACCTCCAGGTCTTAGTTTTATATCTATGAGCCAAAAAGCAT
GGGAAGCTGCAGAAAAATCTAATTTACCAAAATTTTACTTAAATTTAAAATCCTACAAAAAAAGTCTTCAAAGTAACAGT
AATCCATATACTCCAGCAGTTAATTTGGTTTTTGCTTTAGATGAAGCTTTAAAAATGATGCGAGAAGAAGGCTTAGATAA
CATTTTTAGGAGACACAATAAACATAAACTAGCTATGAGCAATGCCGTAAAGGCTTTAAATCTAAAATTATTTGCTGATG
AAAAATATTTAAGCCCTTCAATTACTGCAATAAAAACCGAAGGGATGGATGCTGAAGAATTTAGAAAAACAATAAAAAAT
AATTTTGATATTTTACTTGCTGGTGGTCAAGACCATTTGAAAGGGAAAATATTTAGAGTCGGACATTTAGGTTATGTTAA
TGATAGAGATATTATTACAGTGGTTTCTGCTATTGGAAATACACTTCTCAAAATGCGAAAAATTTCAGCCCAACAAGTTG
GTGAAGCATTAGTTGTAGTATCTAAATATCTTGAGGAAAAATAA

Upstream 100 bases:

>100_bases
CTCCAGCAACCCATAAAGGTAAAGAAAATCCTTTTTTCAAATCAAGTAATTGAAAAATATATAATGAGAACTAATCTAAG
AATGACCTATATAACAAAAA

Downstream 100 bases:

>100_bases
TTTAAGTTCCAGGCTCTTCAACATTTCCGCCTAGTTCAAAAATCTTTTTTCTAAGAACAATCGACTTTTTTTCATCACCG
TTGGTTTGTGCTATTGCTAG

Product: soluble hydrogenase small subunit

Products: NA

Alternate protein names: Tritium exchange subunit [H]

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MAIQQKLSLMIPGPTPVPEKVLQALSKHPIGHRSKEFQDLVQSTTKNLQWLHQTQNDVLTITGSGTAAMEAGIINTLSRG
DKVICGENGKFGERWVKVAKEFGLEVIKIDSEWGIPLDPEEFRKVLEEDKHKEIKAVILTHSETSTGVINDLETISSYIR
KHNTALSIVDCVTSLGACNVPVDEWKLDIVASGSQKGYMIPPGLSFISMSQKAWEAAEKSNLPKFYLNLKSYKKSLQSNS
NPYTPAVNLVFALDEALKMMREEGLDNIFRRHNKHKLAMSNAVKALNLKLFADEKYLSPSITAIKTEGMDAEEFRKTIKN
NFDILLAGGQDHLKGKIFRVGHLGYVNDRDIITVVSAIGNTLLKMRKISAQQVGEALVVVSKYLEEK

Sequences:

>Translated_387_residues
MAIQQKLSLMIPGPTPVPEKVLQALSKHPIGHRSKEFQDLVQSTTKNLQWLHQTQNDVLTITGSGTAAMEAGIINTLSRG
DKVICGENGKFGERWVKVAKEFGLEVIKIDSEWGIPLDPEEFRKVLEEDKHKEIKAVILTHSETSTGVINDLETISSYIR
KHNTALSIVDCVTSLGACNVPVDEWKLDIVASGSQKGYMIPPGLSFISMSQKAWEAAEKSNLPKFYLNLKSYKKSLQSNS
NPYTPAVNLVFALDEALKMMREEGLDNIFRRHNKHKLAMSNAVKALNLKLFADEKYLSPSITAIKTEGMDAEEFRKTIKN
NFDILLAGGQDHLKGKIFRVGHLGYVNDRDIITVVSAIGNTLLKMRKISAQQVGEALVVVSKYLEEK
>Mature_386_residues
AIQQKLSLMIPGPTPVPEKVLQALSKHPIGHRSKEFQDLVQSTTKNLQWLHQTQNDVLTITGSGTAAMEAGIINTLSRGD
KVICGENGKFGERWVKVAKEFGLEVIKIDSEWGIPLDPEEFRKVLEEDKHKEIKAVILTHSETSTGVINDLETISSYIRK
HNTALSIVDCVTSLGACNVPVDEWKLDIVASGSQKGYMIPPGLSFISMSQKAWEAAEKSNLPKFYLNLKSYKKSLQSNSN
PYTPAVNLVFALDEALKMMREEGLDNIFRRHNKHKLAMSNAVKALNLKLFADEKYLSPSITAIKTEGMDAEEFRKTIKNN
FDILLAGGQDHLKGKIFRVGHLGYVNDRDIITVVSAIGNTLLKMRKISAQQVGEALVVVSKYLEEK

Specific function: Soluble hydrogenase catalyzes both production and consumption of hydrogen from suitable artificial electron donors or acceptors. This subunit catalyzes the tritium-exchange activity [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=357, Percent_Identity=31.3725490196078, Blast_Score=171, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17536281, Length=355, Percent_Identity=31.830985915493, Blast_Score=156, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6321079, Length=366, Percent_Identity=26.5027322404372, Blast_Score=103, Evalue=6e-23,
Organism=Drosophila melanogaster, GI17530823, Length=372, Percent_Identity=28.2258064516129, Blast_Score=152, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 43074; Mature: 42943

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIQQKLSLMIPGPTPVPEKVLQALSKHPIGHRSKEFQDLVQSTTKNLQWLHQTQNDVLT
CCCHHCCEEECCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEE
ITGSGTAAMEAGIINTLSRGDKVICGENGKFGERWVKVAKEFGLEVIKIDSEWGIPLDPE
EECCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCHH
EFRKVLEEDKHKEIKAVILTHSETSTGVINDLETISSYIRKHNTALSIVDCVTSLGACNV
HHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
PVDEWKLDIVASGSQKGYMIPPGLSFISMSQKAWEAAEKSNLPKFYLNLKSYKKSLQSNS
CHHHEEEEEEECCCCCCEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCC
NPYTPAVNLVFALDEALKMMREEGLDNIFRRHNKHKLAMSNAVKALNLKLFADEKYLSPS
CCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCHHHHHHHHHHHHEEEEEECCCCCCCC
ITAIKTEGMDAEEFRKTIKNNFDILLAGGQDHLKGKIFRVGHLGYVNDRDIITVVSAIGN
CEEEEECCCCHHHHHHHHHCCCEEEEECCCHHHCCEEEEEEECCCCCCCHHHHHHHHHHH
TLLKMRKISAQQVGEALVVVSKYLEEK
HHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AIQQKLSLMIPGPTPVPEKVLQALSKHPIGHRSKEFQDLVQSTTKNLQWLHQTQNDVLT
CCHHCCEEECCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEE
ITGSGTAAMEAGIINTLSRGDKVICGENGKFGERWVKVAKEFGLEVIKIDSEWGIPLDPE
EECCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCHH
EFRKVLEEDKHKEIKAVILTHSETSTGVINDLETISSYIRKHNTALSIVDCVTSLGACNV
HHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
PVDEWKLDIVASGSQKGYMIPPGLSFISMSQKAWEAAEKSNLPKFYLNLKSYKKSLQSNS
CHHHEEEEEEECCCCCCEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCC
NPYTPAVNLVFALDEALKMMREEGLDNIFRRHNKHKLAMSNAVKALNLKLFADEKYLSPS
CCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCHHHHHHHHHHHHEEEEEECCCCCCCC
ITAIKTEGMDAEEFRKTIKNNFDILLAGGQDHLKGKIFRVGHLGYVNDRDIITVVSAIGN
CEEEEECCCCHHHHHHHHHCCCEEEEECCCHHHCCEEEEEEECCCCCCCHHHHHHHHHHH
TLLKMRKISAQQVGEALVVVSKYLEEK
HHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2129525 [H]