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The map label for this gene is pdxA [H]

Identifier: 126695365

GI number: 126695365

Start: 28350

End: 29339

Strand: Reverse

Name: pdxA [H]

Synonym: P9301_00271

Alternate gene names: 126695365

Gene position: 29339-28350 (Counterclockwise)

Preceding gene: 126695366

Following gene: 126695362

Centisome position: 1.79

GC content: 34.34

Gene sequence:

>990_bases
GTGGGAGATGAGTCAGGTATTGGACCCGAAATAATCTTAAAAGCACTTTGTTCAAATGAGATACCAAAAAATATTGAATT
TAAATTAGTTGGATCAGAAAAAAACCTACATGATACATATGAACACCTTAGATCCTTAGGATTGGAAAGCCTTGCAAATC
CCAAAAATTTAAAGATACATGATCTCGAAGTTTCTTCAACAAATAATAACTCTAAATCAAGTTACGGTGATTCAAGTTTC
CAATATTTAAAAAAAGCAATAGAAATTGTAAAACAATATCCCGATTCAGCACTTGTAACTGGACCAATTTGCAAGAAATC
ATGGTCCTTAGCAGGTCATGACTTCACGGGTCAAACTGAAGTACTAGCAAAATCATGTGGGGTAAAAAACGTTGGAATGT
TATTCACAGCAAAATCACCAATTACAGGTTGGAGATTTAATACTCTACTAGCAACAACCCACATAGCACTTTGTGAAGTT
TCCAAAAAATTAAATACAGAATTAATCCACTCTAAATTAGATCTTTTTAAAGATTTTTGTAATACCTATAATGATAAACC
GACTTTAAAAGTAGCAGGATTAAACCCTCATGCCGGCGAGGAAGGTATTTTAGGACATGAAGAAAAAGATTGGCTCAATG
ATGCATTAATTACATGGTCAAAAAAAAATAGAAACATTAAATTATTAGGCCCTTTATCACCAGATAGTTGCTGGAATTCT
TCCGTAAAAGCCTGGAGTGACAAAAATGCTGAAAAACATGATGGCATTCTTGCTATGTATCATGATCAAGGTTTAATACC
AATGAAAGTGATAGCCCTTAATTACTCAGTAAACACCACAATCGGTTTACCTTTTATAAGAACATCTCCAGATCATGGAA
CAGGATTTGATATTGCTGGCAAAGGAGTTGCTCAATCTCAGAGCATGATTGAGGCGATAAAGGCCGCTGTAGAAATTACT
AACAATTCAAGACTGCTTTACACGCATTAA

Upstream 100 bases:

>100_bases
AAAGTAGGCTTAAAAAATTGCTATCTGAATAGTTAAAAAATAAATTTAAATTTTTATGAATTTACAAAATACAAATAAAC
CATTGAAGGTAGTAATAAGC

Downstream 100 bases:

>100_bases
AACTTGGCCAAATTCTACTGGTGTCCCATTTTCAACGAGAATCTCTACTATTTCAGCATTAAATTCAGATTCAATTTCAT
TCATTAATTTCATTGCTTCC

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MGDESGIGPEIILKALCSNEIPKNIEFKLVGSEKNLHDTYEHLRSLGLESLANPKNLKIHDLEVSSTNNNSKSSYGDSSF
QYLKKAIEIVKQYPDSALVTGPICKKSWSLAGHDFTGQTEVLAKSCGVKNVGMLFTAKSPITGWRFNTLLATTHIALCEV
SKKLNTELIHSKLDLFKDFCNTYNDKPTLKVAGLNPHAGEEGILGHEEKDWLNDALITWSKKNRNIKLLGPLSPDSCWNS
SVKAWSDKNAEKHDGILAMYHDQGLIPMKVIALNYSVNTTIGLPFIRTSPDHGTGFDIAGKGVAQSQSMIEAIKAAVEIT
NNSRLLYTH

Sequences:

>Translated_329_residues
MGDESGIGPEIILKALCSNEIPKNIEFKLVGSEKNLHDTYEHLRSLGLESLANPKNLKIHDLEVSSTNNNSKSSYGDSSF
QYLKKAIEIVKQYPDSALVTGPICKKSWSLAGHDFTGQTEVLAKSCGVKNVGMLFTAKSPITGWRFNTLLATTHIALCEV
SKKLNTELIHSKLDLFKDFCNTYNDKPTLKVAGLNPHAGEEGILGHEEKDWLNDALITWSKKNRNIKLLGPLSPDSCWNS
SVKAWSDKNAEKHDGILAMYHDQGLIPMKVIALNYSVNTTIGLPFIRTSPDHGTGFDIAGKGVAQSQSMIEAIKAAVEIT
NNSRLLYTH
>Mature_328_residues
GDESGIGPEIILKALCSNEIPKNIEFKLVGSEKNLHDTYEHLRSLGLESLANPKNLKIHDLEVSSTNNNSKSSYGDSSFQ
YLKKAIEIVKQYPDSALVTGPICKKSWSLAGHDFTGQTEVLAKSCGVKNVGMLFTAKSPITGWRFNTLLATTHIALCEVS
KKLNTELIHSKLDLFKDFCNTYNDKPTLKVAGLNPHAGEEGILGHEEKDWLNDALITWSKKNRNIKLLGPLSPDSCWNSS
VKAWSDKNAEKHDGILAMYHDQGLIPMKVIALNYSVNTTIGLPFIRTSPDHGTGFDIAGKGVAQSQSMIEAIKAAVEITN
NSRLLYTH

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=334, Percent_Identity=30.8383233532934, Blast_Score=138, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 36180; Mature: 36048

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDESGIGPEIILKALCSNEIPKNIEFKLVGSEKNLHDTYEHLRSLGLESLANPKNLKIH
CCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHCHHHHCCCCCCEEE
DLEVSSTNNNSKSSYGDSSFQYLKKAIEIVKQYPDSALVTGPICKKSWSLAGHDFTGQTE
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCHHCCCCCCCCCCCCHHH
VLAKSCGVKNVGMLFTAKSPITGWRFNTLLATTHIALCEVSKKLNTELIHSKLDLFKDFC
HHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NTYNDKPTLKVAGLNPHAGEEGILGHEEKDWLNDALITWSKKNRNIKLLGPLSPDSCWNS
HHCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHEEEEECCCCCEEEEECCCCCHHCCC
SVKAWSDKNAEKHDGILAMYHDQGLIPMKVIALNYSVNTTIGLPFIRTSPDHGTGFDIAG
CCCCCCCCCCCHHCCEEEEEECCCCCEEEEEEEEEEECCEECCCEEECCCCCCCCCCCCC
KGVAQSQSMIEAIKAAVEITNNSRLLYTH
CCHHHHHHHHHHHHHHHEECCCCEEEEEC
>Mature Secondary Structure 
GDESGIGPEIILKALCSNEIPKNIEFKLVGSEKNLHDTYEHLRSLGLESLANPKNLKIH
CCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHCHHHHCCCCCCEEE
DLEVSSTNNNSKSSYGDSSFQYLKKAIEIVKQYPDSALVTGPICKKSWSLAGHDFTGQTE
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCHHCCCCCCCCCCCCHHH
VLAKSCGVKNVGMLFTAKSPITGWRFNTLLATTHIALCEVSKKLNTELIHSKLDLFKDFC
HHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NTYNDKPTLKVAGLNPHAGEEGILGHEEKDWLNDALITWSKKNRNIKLLGPLSPDSCWNS
HHCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHEEEEECCCCCEEEEECCCCCHHCCC
SVKAWSDKNAEKHDGILAMYHDQGLIPMKVIALNYSVNTTIGLPFIRTSPDHGTGFDIAG
CCCCCCCCCCCHHCCEEEEEECCCCCEEEEEEEEEEECCEECCCEEECCCCCCCCCCCCC
KGVAQSQSMIEAIKAAVEITNNSRLLYTH
CCHHHHHHHHHHHHHHHEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA