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The map label for this gene is yhcW [H]

Identifier: 126455379

GI number: 126455379

Start: 1045050

End: 1045724

Strand: Reverse

Name: yhcW [H]

Synonym: BURPS1106A_1066

Alternate gene names: 126455379

Gene position: 1045724-1045050 (Counterclockwise)

Preceding gene: 126452237

Following gene: 126454662

Centisome position: 26.22

GC content: 73.63

Gene sequence:

>675_bases
ATGTTCTCGGCGGCAATCTTCGATATGGACGGCCTGCTCGTCGATTCCGAGCGGACCATCATGAACGCGTGGATCGACGT
CGCGCGCGCGCACGGCACCGCGCTGTCGGCGGCCGACTACCTGCAGACCGTCGGCCGCTCGTTCCGCGAAGGCCAGGCGA
TCCTCGCCGGCCTGCTCGGCGACGACGCGTTCCGCGCGGTGTCCGCGCAGGTGCGCGAGCAGCTCGCCGCGCCGCGGCCG
CATCCGAAATTTCCGCTCAAGCCGGGCGCGCGGGCGCTGCTGGGCGTGCTCGCCGAGGCGGGCGTGCCGTGCGCGGTCGC
GTCGTCGTCCGCGCGCGACGTGATTCGCACGCGGTTGCACGCGGTCGGCGTGCTCGAGCGTTTCGCCGCGATCGCGGGCG
GCGACGAAGTCGCGCGCGGCAAGCCCGATCCGGCGGTCTACCGGCTCGCGGCCGAGCGGCTGAACGTGTCCGCGCACGCC
TGCGTCGCATTCGAGGACAGCGATTTCGGCGCGCTCGCCGCGACCCGCGCGGGCGCGTCCGTCGTCACCGTGCCCGATCT
GAAGGCGCCGACGCCCGAGATCGTCGCGCTGAGCCTGCGCGTGCTCGATTCGCTCGACGAGGCGATCGCGCTCGTGCCGG
CATGGTTCGGCCCGCGCGCCGCGCCGCTCGCGTAA

Upstream 100 bases:

>100_bases
CGGGCGGCACCGCGCCGGACCAGGTGCGCGCGGCGGCGAAGGCCGCGCGCGCGGCGCTCGGCCAGTAGGCGGGCCGCGCC
TTCACGGACGGGACGATCGC

Downstream 100 bases:

>100_bases
GCCCGGGCGGCACGGCCCTGCCCGGCGCACCTGCGCCCAAGCGCGAATTCGATGTCGGCCGAACAACGAGCGAACGCTCA
CGCCGCCCGATGAGCGACGC

Product: haloacid dehalogenase, IA family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MFSAAIFDMDGLLVDSERTIMNAWIDVARAHGTALSAADYLQTVGRSFREGQAILAGLLGDDAFRAVSAQVREQLAAPRP
HPKFPLKPGARALLGVLAEAGVPCAVASSSARDVIRTRLHAVGVLERFAAIAGGDEVARGKPDPAVYRLAAERLNVSAHA
CVAFEDSDFGALAATRAGASVVTVPDLKAPTPEIVALSLRVLDSLDEAIALVPAWFGPRAAPLA

Sequences:

>Translated_224_residues
MFSAAIFDMDGLLVDSERTIMNAWIDVARAHGTALSAADYLQTVGRSFREGQAILAGLLGDDAFRAVSAQVREQLAAPRP
HPKFPLKPGARALLGVLAEAGVPCAVASSSARDVIRTRLHAVGVLERFAAIAGGDEVARGKPDPAVYRLAAERLNVSAHA
CVAFEDSDFGALAATRAGASVVTVPDLKAPTPEIVALSLRVLDSLDEAIALVPAWFGPRAAPLA
>Mature_224_residues
MFSAAIFDMDGLLVDSERTIMNAWIDVARAHGTALSAADYLQTVGRSFREGQAILAGLLGDDAFRAVSAQVREQLAAPRP
HPKFPLKPGARALLGVLAEAGVPCAVASSSARDVIRTRLHAVGVLERFAAIAGGDEVARGKPDPAVYRLAAERLNVSAHA
CVAFEDSDFGALAATRAGASVVTVPDLKAPTPEIVALSLRVLDSLDEAIALVPAWFGPRAAPLA

Specific function: Unknown

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Homo sapiens, GI197382691, Length=192, Percent_Identity=31.25, Blast_Score=74, Evalue=7e-14,
Organism=Escherichia coli, GI87082080, Length=202, Percent_Identity=33.1683168316832, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1789046, Length=184, Percent_Identity=30.4347826086957, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788021, Length=187, Percent_Identity=31.5508021390374, Blast_Score=67, Evalue=7e-13,
Organism=Drosophila melanogaster, GI45550911, Length=190, Percent_Identity=31.0526315789474, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI20129151, Length=195, Percent_Identity=28.2051282051282, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI116008157, Length=227, Percent_Identity=30.3964757709251, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 23357; Mature: 23357

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSAAIFDMDGLLVDSERTIMNAWIDVARAHGTALSAADYLQTVGRSFREGQAILAGLLG
CCCCEEECCCCEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHC
DDAFRAVSAQVREQLAAPRPHPKFPLKPGARALLGVLAEAGVPCAVASSSARDVIRTRLH
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCHHHHHHHHHHH
AVGVLERFAAIAGGDEVARGKPDPAVYRLAAERLNVSAHACVAFEDSDFGALAATRAGAS
HHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHCCCCE
VVTVPDLKAPTPEIVALSLRVLDSLDEAIALVPAWFGPRAAPLA
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MFSAAIFDMDGLLVDSERTIMNAWIDVARAHGTALSAADYLQTVGRSFREGQAILAGLLG
CCCCEEECCCCEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHC
DDAFRAVSAQVREQLAAPRPHPKFPLKPGARALLGVLAEAGVPCAVASSSARDVIRTRLH
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCHHHHHHHHHHH
AVGVLERFAAIAGGDEVARGKPDPAVYRLAAERLNVSAHACVAFEDSDFGALAATRAGAS
HHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHCCCCE
VVTVPDLKAPTPEIVALSLRVLDSLDEAIALVPAWFGPRAAPLA
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]