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The map label for this gene is msrB [H]

Identifier: 126455298

GI number: 126455298

Start: 2313021

End: 2313476

Strand: Direct

Name: msrB [H]

Synonym: BURPS1106A_2337

Alternate gene names: 126455298

Gene position: 2313021-2313476 (Clockwise)

Preceding gene: 126454265

Following gene: 126452564

Centisome position: 57.99

GC content: 63.38

Gene sequence:

>456_bases
ATGAATTCATCAGGAGAATCGAAGATGTCAGGAGATCGAGACGACCCGCGTTATCCCTACCCGAAGGACGACGCCGAGCT
GCGCCGCCGGCTCACGCCGATGCAGTACGAGGTCACGCAGCACGCGGCGACCGAGCCGCCGTTCACCGGCGAGTACACGG
ACACCGAGGACGCGGGCATCTATCATTGCGTCGTGTGCGGCACCGCGCTGTTCGAATCGGGCGCGAAATACCACTCGGGC
TGCGGCTGGCCCAGCTACTTCAAGCCGATCGACGGCGAGGTGATCGACGAGAAGATGGACTACACGCACGGCATGACCCG
CGTCGAGGTGCGCTGCAACCAGTGCGGCGCGCATCTCGGCCACGTGTTCGAGGACGGCCCGCGCGACAAAACCGGATTGC
GGTACTGCATCAACTCGGCTGCGTTAAACTTCGAGGCTAAGCCCGAGCGCAAGTGA

Upstream 100 bases:

>100_bases
AGCTGGAGCACGACGCGTATGCGGCGCTGCCGCCCGACTGGGCGAGCACGCTCGAGGTGAGCTGCTCGTCGTGACGCCGC
CGGCACGCCGCGCGTTGCGC

Downstream 100 bases:

>100_bases
GCACGGGCCGGCCGAAGAGCCGGCCCGCGCGCCGCGACGGGGCGTCCCTACAACGGTGGCGGGCCCAACGCCCGCCCGCA
GCCGCGAGCACCATGAAATT

Product: methionine-R-sulfoxide reductase

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MNSSGESKMSGDRDDPRYPYPKDDAELRRRLTPMQYEVTQHAATEPPFTGEYTDTEDAGIYHCVVCGTALFESGAKYHSG
CGWPSYFKPIDGEVIDEKMDYTHGMTRVEVRCNQCGAHLGHVFEDGPRDKTGLRYCINSAALNFEAKPERK

Sequences:

>Translated_151_residues
MNSSGESKMSGDRDDPRYPYPKDDAELRRRLTPMQYEVTQHAATEPPFTGEYTDTEDAGIYHCVVCGTALFESGAKYHSG
CGWPSYFKPIDGEVIDEKMDYTHGMTRVEVRCNQCGAHLGHVFEDGPRDKTGLRYCINSAALNFEAKPERK
>Mature_151_residues
MNSSGESKMSGDRDDPRYPYPKDDAELRRRLTPMQYEVTQHAATEPPFTGEYTDTEDAGIYHCVVCGTALFESGAKYHSG
CGWPSYFKPIDGEVIDEKMDYTHGMTRVEVRCNQCGAHLGHVFEDGPRDKTGLRYCINSAALNFEAKPERK

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI37620216, Length=119, Percent_Identity=62.1848739495798, Blast_Score=155, Evalue=9e-39,
Organism=Homo sapiens, GI301336164, Length=119, Percent_Identity=62.1848739495798, Blast_Score=155, Evalue=9e-39,
Organism=Homo sapiens, GI301336162, Length=119, Percent_Identity=62.1848739495798, Blast_Score=155, Evalue=9e-39,
Organism=Homo sapiens, GI73089054, Length=119, Percent_Identity=62.1848739495798, Blast_Score=155, Evalue=9e-39,
Organism=Homo sapiens, GI117606353, Length=134, Percent_Identity=46.2686567164179, Blast_Score=122, Evalue=1e-28,
Organism=Escherichia coli, GI1788077, Length=119, Percent_Identity=53.781512605042, Blast_Score=144, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17553450, Length=150, Percent_Identity=42.6666666666667, Blast_Score=122, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI115532676, Length=150, Percent_Identity=42.6666666666667, Blast_Score=121, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6319816, Length=143, Percent_Identity=39.1608391608392, Blast_Score=103, Evalue=1e-23,
Organism=Drosophila melanogaster, GI221378664, Length=120, Percent_Identity=53.3333333333333, Blast_Score=133, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24645799, Length=153, Percent_Identity=45.7516339869281, Blast_Score=132, Evalue=9e-32,
Organism=Drosophila melanogaster, GI221378662, Length=127, Percent_Identity=51.9685039370079, Blast_Score=132, Evalue=1e-31,
Organism=Drosophila melanogaster, GI45553335, Length=120, Percent_Identity=53.3333333333333, Blast_Score=130, Evalue=4e-31,
Organism=Drosophila melanogaster, GI21356369, Length=120, Percent_Identity=53.3333333333333, Blast_Score=130, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24645801, Length=164, Percent_Identity=43.2926829268293, Blast_Score=126, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24645804, Length=131, Percent_Identity=49.618320610687, Blast_Score=124, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 17008; Mature: 17008

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSSGESKMSGDRDDPRYPYPKDDAELRRRLTPMQYEVTQHAATEPPFTGEYTDTEDAGI
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCE
YHCVVCGTALFESGAKYHSGCGWPSYFKPIDGEVIDEKMDYTHGMTRVEVRCNQCGAHLG
EHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEHHHHHHHHH
HVFEDGPRDKTGLRYCINSAALNFEAKPERK
HHHCCCCCCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNSSGESKMSGDRDDPRYPYPKDDAELRRRLTPMQYEVTQHAATEPPFTGEYTDTEDAGI
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCE
YHCVVCGTALFESGAKYHSGCGWPSYFKPIDGEVIDEKMDYTHGMTRVEVRCNQCGAHLG
EHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEHHHHHHHHH
HVFEDGPRDKTGLRYCINSAALNFEAKPERK
HHHCCCCCCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA