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The map label for this gene is glnA [H]

Identifier: 126455077

GI number: 126455077

Start: 2680676

End: 2682010

Strand: Reverse

Name: glnA [H]

Synonym: BURPS1106A_2711

Alternate gene names: 126455077

Gene position: 2682010-2680676 (Counterclockwise)

Preceding gene: 126454462

Following gene: 126454173

Centisome position: 67.24

GC content: 64.19

Gene sequence:

>1335_bases
ATGCAAGACATCGATGATTTTTTGAGGCAGCACCGGATCACCGAAGTGGAAGCGATCATTCCCGACATGGCGGGCATCGC
GCGCGGCAAGATCATTCCGCGCAACAAGTTCGAAACCGGCGAATCGATGCGCCTGCCGCAAGCAGTGATGGTGCAGACCG
TCACCGGCGATTATCCGGAGGACGGCACGCTCACGGGCGTCACGGATCCCGACATGGTGTGCGTGGCCGACGCGTCGACG
ATCTGCCTGATTCCGTGGGCAGTCGACCCCACCGCGCAGGTGATTCACGATTGCGTGCATTTCGACGGCTCGCCCGTCGA
AATCTCGCCGCGCTACGTGCTGCGCCGCGTGCTCGACCTGTATCGCGCGAAGGGGTGGAAGCCCGTCGTCGCGCCGGAGC
TCGAGTTCTATCTGGTCGACATGAACAAGGACCCGGACCTGCCGCTGCGGCCGCCCGTCGGACGCACGGGGCGCGCGGAA
ACGGGGCGGCAGTCGTACTCGATCGAAGCGGTCAACGAATTCGATCCGCTCTTCGAGGACATCTACGAGTACTGCGAGCT
GCAGGGCCTCGACATCGACACGCTGATTCACGAAGTCGGCGCCGCGCAGATGGAGATCAACTTCCTGCACGGCGATGCGC
TATCGCTCGCCGACCAGGTGTTTCTGTTCAAGCGCACGGTGCGCGAGGCGGCGCTGCGCCACAACATGTACGCCACCTTC
ATGGCAAAGCCGATGGAGAGCGAGCCCGGCTCGGCGATGCACATTCATCAGAGCGTCGTCGACATCGAGACCGGGCGCAA
TCTCTTCATCGGCGCGAGCGGCGACGTGACGCCGATGTTCCGCAGCTATCTCGCCGGGCTGCAGAAGTACACGCCCGCGC
TGATGCCGATCTTCGCGCCGTACATCAACTCGTACCGGCGGCTGTCGCGCTTCATGGCCGCGCCGATCAACGTGCAATGG
GGCTACGACAACCGCACGGTCGGCTTCCGGATTCCGCACTCGGCGGCCGCCGCGCGGCGGATCGAGAACCGGATTCCGGG
CGTCGACTGCAACCCGTATCTCGCGATCGCGGGCACGCTCGCGGCGGGCTACCTCGGCGTCACGCAGGGGCTCGAGCCGA
CCGAGCCGCTCGCGAGCGACGGCTACAGCCTGCCGTATCAACTGCCGCGCAATCTGGAGGAAGGGCTCACGCTGATGAGC
GCATGCGCGCCGCTTGCCGAGATGCTCGGCGAGAAATTCGTGAAAGCCTATCTCGCATTGAAGGAAACGGAGTACGAAGC
ATTTTTCCGCGTGATCAGCTCGTGGGAGCGCAGGCACCTGCTGCTGCACGTTTGA

Upstream 100 bases:

>100_bases
TTGCGGCGTTCGGCGCGGCGTGCCGCGCGCGAAGACGCGCGACGGCCGGGCGCGCGCCGCGCGCGTGACGGCCGTCGACG
CTTATCGAAGAGAGGCTCAC

Downstream 100 bases:

>100_bases
GCGTGCGCACGCACGCCGCATTCAGGAGATCCAAGTGACGTATCGAACCGAAGACATCGCCGATGTAGCGCCGCTGTACG
CGAGCGCCGCGCCCGCGCAC

Product: glutamine synthetase catalytic domain

Products: NA

Alternate protein names: Gamma-Glu-Put synthetase; Glutamate--putrescine ligase [H]

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MQDIDDFLRQHRITEVEAIIPDMAGIARGKIIPRNKFETGESMRLPQAVMVQTVTGDYPEDGTLTGVTDPDMVCVADAST
ICLIPWAVDPTAQVIHDCVHFDGSPVEISPRYVLRRVLDLYRAKGWKPVVAPELEFYLVDMNKDPDLPLRPPVGRTGRAE
TGRQSYSIEAVNEFDPLFEDIYEYCELQGLDIDTLIHEVGAAQMEINFLHGDALSLADQVFLFKRTVREAALRHNMYATF
MAKPMESEPGSAMHIHQSVVDIETGRNLFIGASGDVTPMFRSYLAGLQKYTPALMPIFAPYINSYRRLSRFMAAPINVQW
GYDNRTVGFRIPHSAAAARRIENRIPGVDCNPYLAIAGTLAAGYLGVTQGLEPTEPLASDGYSLPYQLPRNLEEGLTLMS
ACAPLAEMLGEKFVKAYLALKETEYEAFFRVISSWERRHLLLHV

Sequences:

>Translated_444_residues
MQDIDDFLRQHRITEVEAIIPDMAGIARGKIIPRNKFETGESMRLPQAVMVQTVTGDYPEDGTLTGVTDPDMVCVADAST
ICLIPWAVDPTAQVIHDCVHFDGSPVEISPRYVLRRVLDLYRAKGWKPVVAPELEFYLVDMNKDPDLPLRPPVGRTGRAE
TGRQSYSIEAVNEFDPLFEDIYEYCELQGLDIDTLIHEVGAAQMEINFLHGDALSLADQVFLFKRTVREAALRHNMYATF
MAKPMESEPGSAMHIHQSVVDIETGRNLFIGASGDVTPMFRSYLAGLQKYTPALMPIFAPYINSYRRLSRFMAAPINVQW
GYDNRTVGFRIPHSAAAARRIENRIPGVDCNPYLAIAGTLAAGYLGVTQGLEPTEPLASDGYSLPYQLPRNLEEGLTLMS
ACAPLAEMLGEKFVKAYLALKETEYEAFFRVISSWERRHLLLHV
>Mature_444_residues
MQDIDDFLRQHRITEVEAIIPDMAGIARGKIIPRNKFETGESMRLPQAVMVQTVTGDYPEDGTLTGVTDPDMVCVADAST
ICLIPWAVDPTAQVIHDCVHFDGSPVEISPRYVLRRVLDLYRAKGWKPVVAPELEFYLVDMNKDPDLPLRPPVGRTGRAE
TGRQSYSIEAVNEFDPLFEDIYEYCELQGLDIDTLIHEVGAAQMEINFLHGDALSLADQVFLFKRTVREAALRHNMYATF
MAKPMESEPGSAMHIHQSVVDIETGRNLFIGASGDVTPMFRSYLAGLQKYTPALMPIFAPYINSYRRLSRFMAAPINVQW
GYDNRTVGFRIPHSAAAARRIENRIPGVDCNPYLAIAGTLAAGYLGVTQGLEPTEPLASDGYSLPYQLPRNLEEGLTLMS
ACAPLAEMLGEKFVKAYLALKETEYEAFFRVISSWERRHLLLHV

Specific function: Involved in the breakdown of putrescine via the biosynthesis of gamma-L-glutamylputrescine [H]

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=443, Percent_Identity=26.86230248307, Blast_Score=154, Evalue=2e-37,
Organism=Escherichia coli, GI87081870, Length=450, Percent_Identity=35.1111111111111, Blast_Score=241, Evalue=6e-65,
Organism=Escherichia coli, GI1790301, Length=463, Percent_Identity=28.0777537796976, Blast_Score=129, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146 [H]

Pfam domain/function: PF00120 Gln-synt_C [H]

EC number: =6.3.1.11 [H]

Molecular weight: Translated: 49707; Mature: 49707

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00181 GLNA_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDIDDFLRQHRITEVEAIIPDMAGIARGKIIPRNKFETGESMRLPQAVMVQTVTGDYPE
CCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHEEECCCCCCC
DGTLTGVTDPDMVCVADASTICLIPWAVDPTAQVIHDCVHFDGSPVEISPRYVLRRVLDL
CCEEECCCCCCEEEEECCCEEEEEEECCCHHHHHHHHHHHCCCCCEEECHHHHHHHHHHH
YRAKGWKPVVAPELEFYLVDMNKDPDLPLRPPVGRTGRAETGRQSYSIEAVNEFDPLFED
HHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHH
IYEYCELQGLDIDTLIHEVGAAQMEINFLHGDALSLADQVFLFKRTVREAALRHNMYATF
HHHHHHCCCCCHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MAKPMESEPGSAMHIHQSVVDIETGRNLFIGASGDVTPMFRSYLAGLQKYTPALMPIFAP
HCCCCCCCCCCEEEHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCHHHHHHHHH
YINSYRRLSRFMAAPINVQWGYDNRTVGFRIPHSAAAARRIENRIPGVDCNPYLAIAGTL
HHHHHHHHHHHHCCCCEEEECCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHH
AAGYLGVTQGLEPTEPLASDGYSLPYQLPRNLEEGLTLMSACAPLAEMLGEKFVKAYLAL
HHHHHHHHCCCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KETEYEAFFRVISSWERRHLLLHV
HHHHHHHHHHHHHHHHHCEEEEEC
>Mature Secondary Structure
MQDIDDFLRQHRITEVEAIIPDMAGIARGKIIPRNKFETGESMRLPQAVMVQTVTGDYPE
CCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHEEECCCCCCC
DGTLTGVTDPDMVCVADASTICLIPWAVDPTAQVIHDCVHFDGSPVEISPRYVLRRVLDL
CCEEECCCCCCEEEEECCCEEEEEEECCCHHHHHHHHHHHCCCCCEEECHHHHHHHHHHH
YRAKGWKPVVAPELEFYLVDMNKDPDLPLRPPVGRTGRAETGRQSYSIEAVNEFDPLFED
HHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHH
IYEYCELQGLDIDTLIHEVGAAQMEINFLHGDALSLADQVFLFKRTVREAALRHNMYATF
HHHHHHCCCCCHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MAKPMESEPGSAMHIHQSVVDIETGRNLFIGASGDVTPMFRSYLAGLQKYTPALMPIFAP
HCCCCCCCCCCEEEHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCHHHHHHHHH
YINSYRRLSRFMAAPINVQWGYDNRTVGFRIPHSAAAARRIENRIPGVDCNPYLAIAGTL
HHHHHHHHHHHHCCCCEEEECCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHH
AAGYLGVTQGLEPTEPLASDGYSLPYQLPRNLEEGLTLMSACAPLAEMLGEKFVKAYLAL
HHHHHHHHCCCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KETEYEAFFRVISSWERRHLLLHV
HHHHHHHHHHHHHHHHHCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]