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The map label for this gene is argM [C]

Identifier: 126454173

GI number: 126454173

Start: 2679214

End: 2680641

Strand: Reverse

Name: argM [C]

Synonym: BURPS1106A_2710

Alternate gene names: 126454173

Gene position: 2680641-2679214 (Counterclockwise)

Preceding gene: 126455077

Following gene: 126452412

Centisome position: 67.21

GC content: 67.58

Gene sequence:

>1428_bases
GTGACGTATCGAACCGAAGACATCGCCGATGTAGCGCCGCTGTACGCGAGCGCCGCGCCCGCGCACCGCACGAGCGCCGA
ATACCGCGCGCTCGACGCCGCGCACCACCTCCACCCGTTCTCGGACATGGGCTCGCTCAATCGCGCGGGCAGCCGCGTGA
TCGTGAAGGCCGAAGGCGTCCACCTGTGGGATTCCGACGGCAACAGGATCATCGACGGCATGGCCGGGCTCTGGTGCGTG
AACGTCGGCTACGGCCGCGACGAGCTGATCGAGGCCGGCAGCCGCCAGTTGCGCGAGCTGCCGTTCTACAACACCTTCTT
CAAGACCACCCATCCGCCCGTCATCGAGCTGTCCGCGCTGCTCGCGCAGATCGCGCCGCCCGCGTTCAACCGCTTCTTCT
ATTGCAACAGCGGCTCCGAGGGCAACGACACGGTGCTGCGCATCGCGCATCAGTACTGGCGCGCGCAGAACCGCCCGCAG
AAGAAGTTCGTCATTTCGCGCCGAAACGGCTACCACGGCTCGACGATCGCGGGCGCGACGCTCGGCGGCATGGGCTACAT
GCACGAGCAGATGCCCTCGAAGGTCGAGCACATCGTCCACATCGATCAGCCCTATTACTTCGGCGAAGCGCGCGAGGGGC
AGACGCCCGAGGCGTTCGGCCTCGAGCGCGCGCGACAGCTCGAAGCGAAGATTCTCGAGCTCGGCGCGCAGAACGTCGCG
GCGTTCATCGGCGAGCCGTTCCAGGGCGCGGGCGGCGTGATCTTTCCGCCGTCGACGTACTGGCCGGAGATCGAGCGGAT
CTGCCGCCAGTACGACGTGCTGCTCGTCGCCGACGAAGTGATCGGCGGCTTCGGGCGCACCGGCGAATGGTTCGCGCACC
AGCACTTCGGCTTCGCGCCCGACCTGATGACGCTCGCCAAGGGCCTGACGAGCGGTTACGTGCCGATGGGCGCGGTCGCG
CTGTCGGACCGGATCGCCGACGCGCTGATCGCGCACGGCGAGTTCAACCACGGGATGACGTACTCCGGGCATCCGGTCGC
GGCGGCGGTGGCCGTCGCGAATCTGAAGGTGCTGCGCGACGAGCGGATCGTCGAGCGCGTGAAGACCGATACCGGCCCCT
ACTTCCAGCAGCGGTTGCGCGAAACGTTCGCGAACCATTCGATCGTCGGCGACATCGCCGGCGCGGGGCTCGTCGCGGGC
ATCCAGCTCGCGCGCGAGCCGCGCACGCGCAAGCGCTTCGAGAACGGCGGCGAAGTCGGCACGATCTGCCGCGACTACTG
CTTCAACGGCAACCTGATCATGCGCGCGACGGGCGACCGGATGCTGCTGTCGCCGCCGCTCGTGATCTCGAAACCGCAGA
TCGACGAGATCGTCGAGAAGGCGAAGCGCGCGATCGATGCGACGGCCAAGCAGTTGGGGTTTGCGTGA

Upstream 100 bases:

>100_bases
GAGTACGAAGCATTTTTCCGCGTGATCAGCTCGTGGGAGCGCAGGCACCTGCTGCTGCACGTTTGAGCGTGCGCACGCAC
GCCGCATTCAGGAGATCCAA

Downstream 100 bases:

>100_bases
TGCGGGGTAGGGGGCGCAGCGGCCTTGTCGGGCATTCTTTTCGTGCGATAGGCGTGGCTTCTATCCACCGTTGGCGCAAT
GCCGCTGATCGAATGCGCTG

Product: putative aminotransferase

Products: L-glutamate; N2-succinylglutamic-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MTYRTEDIADVAPLYASAAPAHRTSAEYRALDAAHHLHPFSDMGSLNRAGSRVIVKAEGVHLWDSDGNRIIDGMAGLWCV
NVGYGRDELIEAGSRQLRELPFYNTFFKTTHPPVIELSALLAQIAPPAFNRFFYCNSGSEGNDTVLRIAHQYWRAQNRPQ
KKFVISRRNGYHGSTIAGATLGGMGYMHEQMPSKVEHIVHIDQPYYFGEAREGQTPEAFGLERARQLEAKILELGAQNVA
AFIGEPFQGAGGVIFPPSTYWPEIERICRQYDVLLVADEVIGGFGRTGEWFAHQHFGFAPDLMTLAKGLTSGYVPMGAVA
LSDRIADALIAHGEFNHGMTYSGHPVAAAVAVANLKVLRDERIVERVKTDTGPYFQQRLRETFANHSIVGDIAGAGLVAG
IQLAREPRTRKRFENGGEVGTICRDYCFNGNLIMRATGDRMLLSPPLVISKPQIDEIVEKAKRAIDATAKQLGFA

Sequences:

>Translated_475_residues
MTYRTEDIADVAPLYASAAPAHRTSAEYRALDAAHHLHPFSDMGSLNRAGSRVIVKAEGVHLWDSDGNRIIDGMAGLWCV
NVGYGRDELIEAGSRQLRELPFYNTFFKTTHPPVIELSALLAQIAPPAFNRFFYCNSGSEGNDTVLRIAHQYWRAQNRPQ
KKFVISRRNGYHGSTIAGATLGGMGYMHEQMPSKVEHIVHIDQPYYFGEAREGQTPEAFGLERARQLEAKILELGAQNVA
AFIGEPFQGAGGVIFPPSTYWPEIERICRQYDVLLVADEVIGGFGRTGEWFAHQHFGFAPDLMTLAKGLTSGYVPMGAVA
LSDRIADALIAHGEFNHGMTYSGHPVAAAVAVANLKVLRDERIVERVKTDTGPYFQQRLRETFANHSIVGDIAGAGLVAG
IQLAREPRTRKRFENGGEVGTICRDYCFNGNLIMRATGDRMLLSPPLVISKPQIDEIVEKAKRAIDATAKQLGFA
>Mature_474_residues
TYRTEDIADVAPLYASAAPAHRTSAEYRALDAAHHLHPFSDMGSLNRAGSRVIVKAEGVHLWDSDGNRIIDGMAGLWCVN
VGYGRDELIEAGSRQLRELPFYNTFFKTTHPPVIELSALLAQIAPPAFNRFFYCNSGSEGNDTVLRIAHQYWRAQNRPQK
KFVISRRNGYHGSTIAGATLGGMGYMHEQMPSKVEHIVHIDQPYYFGEAREGQTPEAFGLERARQLEAKILELGAQNVAA
FIGEPFQGAGGVIFPPSTYWPEIERICRQYDVLLVADEVIGGFGRTGEWFAHQHFGFAPDLMTLAKGLTSGYVPMGAVAL
SDRIADALIAHGEFNHGMTYSGHPVAAAVAVANLKVLRDERIVERVKTDTGPYFQQRLRETFANHSIVGDIAGAGLVAGI
QLAREPRTRKRFENGGEVGTICRDYCFNGNLIMRATGDRMLLSPPLVISKPQIDEIVEKAKRAIDATAKQLGFA

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI37574042, Length=370, Percent_Identity=29.7297297297297, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI13994255, Length=423, Percent_Identity=28.1323877068558, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI226442705, Length=367, Percent_Identity=29.9727520435967, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI24119277, Length=360, Percent_Identity=28.8888888888889, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI226442709, Length=323, Percent_Identity=30.6501547987616, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI4557809, Length=446, Percent_Identity=27.1300448430493, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI284507298, Length=228, Percent_Identity=32.8947368421053, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI188536080, Length=286, Percent_Identity=26.5734265734266, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI38679950, Length=286, Percent_Identity=26.5734265734266, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI38679946, Length=286, Percent_Identity=26.5734265734266, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI1788044, Length=415, Percent_Identity=26.9879518072289, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1786991, Length=447, Percent_Identity=28.8590604026846, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI1789759, Length=415, Percent_Identity=27.710843373494, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI145693181, Length=413, Percent_Identity=25.90799031477, Blast_Score=145, Evalue=7e-36,
Organism=Escherichia coli, GI1789016, Length=430, Percent_Identity=26.7441860465116, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1787560, Length=427, Percent_Identity=28.8056206088993, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1786349, Length=307, Percent_Identity=25.7328990228013, Blast_Score=80, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71992977, Length=427, Percent_Identity=28.3372365339578, Blast_Score=155, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI25144271, Length=423, Percent_Identity=27.6595744680851, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI32564660, Length=449, Percent_Identity=29.1759465478842, Blast_Score=147, Evalue=9e-36,
Organism=Caenorhabditis elegans, GI25144274, Length=235, Percent_Identity=33.6170212765957, Blast_Score=135, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6323470, Length=462, Percent_Identity=26.4069264069264, Blast_Score=168, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6324386, Length=366, Percent_Identity=30.8743169398907, Blast_Score=139, Evalue=8e-34,
Organism=Saccharomyces cerevisiae, GI6324432, Length=432, Percent_Identity=25.2314814814815, Blast_Score=127, Evalue=3e-30,
Organism=Drosophila melanogaster, GI161085790, Length=426, Percent_Identity=28.8732394366197, Blast_Score=153, Evalue=3e-37,
Organism=Drosophila melanogaster, GI28574759, Length=430, Percent_Identity=29.3023255813954, Blast_Score=153, Evalue=3e-37,
Organism=Drosophila melanogaster, GI21356575, Length=371, Percent_Identity=29.9191374663073, Blast_Score=145, Evalue=7e-35,
Organism=Drosophila melanogaster, GI21357415, Length=440, Percent_Identity=27.5, Blast_Score=145, Evalue=7e-35,
Organism=Drosophila melanogaster, GI281366494, Length=342, Percent_Identity=23.6842105263158, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24667139, Length=342, Percent_Identity=23.6842105263158, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24667143, Length=342, Percent_Identity=23.6842105263158, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 52315; Mature: 52184

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYRTEDIADVAPLYASAAPAHRTSAEYRALDAAHHLHPFSDMGSLNRAGSRVIVKAEGV
CCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHCCHHCCCCEEEEEECCE
HLWDSDGNRIIDGMAGLWCVNVGYGRDELIEAGSRQLRELPFYNTFFKTTHPPVIELSAL
EEECCCCCEEHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHH
LAQIAPPAFNRFFYCNSGSEGNDTVLRIAHQYWRAQNRPQKKFVISRRNGYHGSTIAGAT
HHHHCCCHHCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCHHEEEECCCCCCCCCCCCHH
LGGMGYMHEQMPSKVEHIVHIDQPYYFGEAREGQTPEAFGLERARQLEAKILELGAQNVA
HCCHHHHHHHHHHHHHHHEECCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AFIGEPFQGAGGVIFPPSTYWPEIERICRQYDVLLVADEVIGGFGRTGEWFAHQHFGFAP
HHHCCCCCCCCCEEECCCCCCHHHHHHHHHHCEEEEEHHHHCCCCCCCHHHHHHCCCCCH
DLMTLAKGLTSGYVPMGAVALSDRIADALIAHGEFNHGMTYSGHPVAAAVAVANLKVLRD
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ERIVERVKTDTGPYFQQRLRETFANHSIVGDIAGAGLVAGIQLAREPRTRKRFENGGEVG
HHHHHHHHCCCCHHHHHHHHHHHHCCCEEHHHHCCHHHHHHHHHCCCHHHHHHHCCCCHH
TICRDYCFNGNLIMRATGDRMLLSPPLVISKPQIDEIVEKAKRAIDATAKQLGFA
HHHHHHHCCCCEEEEECCCEEEECCCCEECCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TYRTEDIADVAPLYASAAPAHRTSAEYRALDAAHHLHPFSDMGSLNRAGSRVIVKAEGV
CCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHCCHHCCCCEEEEEECCE
HLWDSDGNRIIDGMAGLWCVNVGYGRDELIEAGSRQLRELPFYNTFFKTTHPPVIELSAL
EEECCCCCEEHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHH
LAQIAPPAFNRFFYCNSGSEGNDTVLRIAHQYWRAQNRPQKKFVISRRNGYHGSTIAGAT
HHHHCCCHHCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCHHEEEECCCCCCCCCCCCHH
LGGMGYMHEQMPSKVEHIVHIDQPYYFGEAREGQTPEAFGLERARQLEAKILELGAQNVA
HCCHHHHHHHHHHHHHHHEECCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AFIGEPFQGAGGVIFPPSTYWPEIERICRQYDVLLVADEVIGGFGRTGEWFAHQHFGFAP
HHHCCCCCCCCCEEECCCCCCHHHHHHHHHHCEEEEEHHHHCCCCCCCHHHHHHCCCCCH
DLMTLAKGLTSGYVPMGAVALSDRIADALIAHGEFNHGMTYSGHPVAAAVAVANLKVLRD
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ERIVERVKTDTGPYFQQRLRETFANHSIVGDIAGAGLVAGIQLAREPRTRKRFENGGEVG
HHHHHHHHCCCCHHHHHHHHHHHHCCCEEHHHHCCHHHHHHHHHCCCHHHHHHHCCCCHH
TICRDYCFNGNLIMRATGDRMLLSPPLVISKPQIDEIVEKAKRAIDATAKQLGFA
HHHHHHHCCCCEEEEECCCEEEECCCCEECCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-alpha-acetylornithine; 2-oxoglutarate [C]

Specific reaction: N-alpha-acetylornithine + 2-oxoglutarate = N-acetylglutamate semialdehyde + L-glutamate N2-succinylornithine + 2-oxoglutarate = N2-succinylglutamic-semialdehyde + L-glutamate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]