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The map label for this gene is ybdL [H]

Identifier: 126455071

GI number: 126455071

Start: 1297443

End: 1298618

Strand: Reverse

Name: ybdL [H]

Synonym: BURPS1106A_1328

Alternate gene names: 126455071

Gene position: 1298618-1297443 (Counterclockwise)

Preceding gene: 126452371

Following gene: 126453807

Centisome position: 32.56

GC content: 66.41

Gene sequence:

>1176_bases
ATGATGAACGCACCGCACGACATGCCGACGACGCCCACTCTCCTCTCGCGCCTGCCCGAGGTCGGCACGACGATTTTCAC
GGTCATGAGCGCGCTCGCCGCGGAAAAGGGCGCGGTCAATCTCGGCCAGGGCTTTCCCGACTTCGATTGCGATCCGCGCA
TCGTCGACGCGGTCGCGCACGCGATGCGCGACGGCCGCAACCAGTATCCGCCGATGGCGGGCGTCGCGCCGCTGCGTGAA
GCGATCGCCGACAAGATCGAGCGGCTTTACGGCCGCCGCTACGATGCCGCGACCGAGATCACCGTGACGGCGGGCGCGAC
CCAGGCGCTCCTGACCGCGATCCTGTGCGCGGTGCATCCGGGCGACGAGGTGATCGTGATCGAGCCCACCTACGACAGCT
ACCTGCCGTCGATCGAGCTGGCGGGCGCAACGCCCGTGTTCGTCACGCTGAACGCGCCCGACTACGCGATTCCGTTCGAC
AAGCTCGCCGCGGCGATCACGCCGAAGACGCGCGCGATCCTGATCAACACGCCGCACAATCCGACGGGCACCGTCTGGCG
CGAGGCGGACATGCGCGCGCTCGAGGACATCGTGCGCGGCACCGGCCTGCTGATCGTGTCCGACGAGGTCTACGAGCACA
TGGTCTACGACGGCGCGCGGCACGAAAGCGTCGCCCGCTACCCGGAACTCGCCGCGCGCAGCATCATCGTGTCGAGCTTC
GGCAAGACCTTTCACGTGACGGGCTGGAAGATCGGCTACGTCGCCGCGCCCGCGCCGCTCACGGCCGAGTTCCGCAAGGT
GCATCAGTTCAACGTGTTCACGGTCAATACGCCGATGCAATTCGGCCTCGCCGATTATCTGCGCGATCCCGAGCCGTATC
TGACGCTGCCCGCGTTCTATCAGCAAAAGCGCGACTTCTTCCGCGCCGGGCTCGCGAACACGCGCTTCGCGCTGCTGCCC
TGCGCGGGGACATACTTCCAGTGCGTCGATTATTCGGCGATCAGCGATCTGCCGGAAGCGGAGTTCGCAAAATGGCTGAC
GACCGAAATCGGCGTCGCCGCGATTCCGGTATCGGCGTTCTATCACGAGCCGCATGAATCGGGCGTCGTGCGCTTTTGCT
TCGCGAAGCGCGAAGACACGCTCGCCACCGCGCTCGAGCGGCTCGCACGCCTGTAG

Upstream 100 bases:

>100_bases
GCCCGCGCCGTTCGCCGCGAGCGCGCTCGCGGCCGACGCATCCGAGCCGGCGTAAGCGACGCACTCGCCCGAGCCGCCCC
CACCCCTTTTCGCGCAAGCC

Downstream 100 bases:

>100_bases
CCTCCGACAAAACGCGCCGCGAACGCGCAGCACGCGCGCACGCGCCGCCGCGGGTAAGCGCGTGCCGGTGCGCGGAAGAA
ATGATCCTTCGAGCGAGCGA

Product: putative aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MMNAPHDMPTTPTLLSRLPEVGTTIFTVMSALAAEKGAVNLGQGFPDFDCDPRIVDAVAHAMRDGRNQYPPMAGVAPLRE
AIADKIERLYGRRYDAATEITVTAGATQALLTAILCAVHPGDEVIVIEPTYDSYLPSIELAGATPVFVTLNAPDYAIPFD
KLAAAITPKTRAILINTPHNPTGTVWREADMRALEDIVRGTGLLIVSDEVYEHMVYDGARHESVARYPELAARSIIVSSF
GKTFHVTGWKIGYVAAPAPLTAEFRKVHQFNVFTVNTPMQFGLADYLRDPEPYLTLPAFYQQKRDFFRAGLANTRFALLP
CAGTYFQCVDYSAISDLPEAEFAKWLTTEIGVAAIPVSAFYHEPHESGVVRFCFAKREDTLATALERLARL

Sequences:

>Translated_391_residues
MMNAPHDMPTTPTLLSRLPEVGTTIFTVMSALAAEKGAVNLGQGFPDFDCDPRIVDAVAHAMRDGRNQYPPMAGVAPLRE
AIADKIERLYGRRYDAATEITVTAGATQALLTAILCAVHPGDEVIVIEPTYDSYLPSIELAGATPVFVTLNAPDYAIPFD
KLAAAITPKTRAILINTPHNPTGTVWREADMRALEDIVRGTGLLIVSDEVYEHMVYDGARHESVARYPELAARSIIVSSF
GKTFHVTGWKIGYVAAPAPLTAEFRKVHQFNVFTVNTPMQFGLADYLRDPEPYLTLPAFYQQKRDFFRAGLANTRFALLP
CAGTYFQCVDYSAISDLPEAEFAKWLTTEIGVAAIPVSAFYHEPHESGVVRFCFAKREDTLATALERLARL
>Mature_391_residues
MMNAPHDMPTTPTLLSRLPEVGTTIFTVMSALAAEKGAVNLGQGFPDFDCDPRIVDAVAHAMRDGRNQYPPMAGVAPLRE
AIADKIERLYGRRYDAATEITVTAGATQALLTAILCAVHPGDEVIVIEPTYDSYLPSIELAGATPVFVTLNAPDYAIPFD
KLAAAITPKTRAILINTPHNPTGTVWREADMRALEDIVRGTGLLIVSDEVYEHMVYDGARHESVARYPELAARSIIVSSF
GKTFHVTGWKIGYVAAPAPLTAEFRKVHQFNVFTVNTPMQFGLADYLRDPEPYLTLPAFYQQKRDFFRAGLANTRFALLP
CAGTYFQCVDYSAISDLPEAEFAKWLTTEIGVAAIPVSAFYHEPHESGVVRFCFAKREDTLATALERLARL

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=401, Percent_Identity=35.6608478802993, Blast_Score=237, Evalue=2e-62,
Organism=Homo sapiens, GI56713256, Length=402, Percent_Identity=35.5721393034826, Blast_Score=236, Evalue=2e-62,
Organism=Homo sapiens, GI95147551, Length=409, Percent_Identity=34.718826405868, Blast_Score=228, Evalue=6e-60,
Organism=Homo sapiens, GI169881279, Length=409, Percent_Identity=34.718826405868, Blast_Score=228, Evalue=6e-60,
Organism=Homo sapiens, GI169881281, Length=407, Percent_Identity=30.2211302211302, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI4507369, Length=217, Percent_Identity=26.2672811059908, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI1786816, Length=377, Percent_Identity=53.0503978779841, Blast_Score=413, Evalue=1e-117,
Organism=Escherichia coli, GI1788722, Length=386, Percent_Identity=25.9067357512953, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1788627, Length=193, Percent_Identity=29.0155440414508, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1787710, Length=299, Percent_Identity=26.7558528428094, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71994472, Length=416, Percent_Identity=34.8557692307692, Blast_Score=224, Evalue=7e-59,
Organism=Caenorhabditis elegans, GI71994476, Length=416, Percent_Identity=34.8557692307692, Blast_Score=224, Evalue=8e-59,
Organism=Caenorhabditis elegans, GI17567369, Length=399, Percent_Identity=32.5814536340852, Blast_Score=200, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI17567663, Length=203, Percent_Identity=27.0935960591133, Blast_Score=75, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6322401, Length=392, Percent_Identity=32.6530612244898, Blast_Score=190, Evalue=3e-49,
Organism=Drosophila melanogaster, GI28573069, Length=414, Percent_Identity=35.2657004830918, Blast_Score=238, Evalue=4e-63,
Organism=Drosophila melanogaster, GI24646114, Length=414, Percent_Identity=35.2657004830918, Blast_Score=238, Evalue=4e-63,
Organism=Drosophila melanogaster, GI28573067, Length=414, Percent_Identity=35.2657004830918, Blast_Score=238, Evalue=4e-63,
Organism=Drosophila melanogaster, GI28573065, Length=414, Percent_Identity=35.2657004830918, Blast_Score=238, Evalue=4e-63,
Organism=Drosophila melanogaster, GI18859735, Length=205, Percent_Identity=30.2439024390244, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 42975; Mature: 42975

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNAPHDMPTTPTLLSRLPEVGTTIFTVMSALAAEKGAVNLGQGFPDFDCDPRIVDAVAH
CCCCCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHH
AMRDGRNQYPPMAGVAPLREAIADKIERLYGRRYDAATEITVTAGATQALLTAILCAVHP
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHCCC
GDEVIVIEPTYDSYLPSIELAGATPVFVTLNAPDYAIPFDKLAAAITPKTRAILINTPHN
CCEEEEEECCHHHHCCCEEECCCCEEEEEECCCCCCCCHHHHHHHCCCCCCEEEEECCCC
PTGTVWREADMRALEDIVRGTGLLIVSDEVYEHMVYDGARHESVARYPELAARSIIVSSF
CCCCEEHHHHHHHHHHHHCCCCEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHC
GKTFHVTGWKIGYVAAPAPLTAEFRKVHQFNVFTVNTPMQFGLADYLRDPEPYLTLPAFY
CCEEEECCEEEEEEECCCCCHHHHHHHHEEEEEEECCCHHHCHHHHHCCCCCCEECHHHH
QQKRDFFRAGLANTRFALLPCAGTYFQCVDYSAISDLPEAEFAKWLTTEIGVAAIPVSAF
HHHHHHHHHCCCCCCEEEEECCCCHHHHHCHHHHHCCCHHHHHHHHHHHCCHHEEEHHHH
YHEPHESGVVRFCFAKREDTLATALERLARL
HCCCCCCCEEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MMNAPHDMPTTPTLLSRLPEVGTTIFTVMSALAAEKGAVNLGQGFPDFDCDPRIVDAVAH
CCCCCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHH
AMRDGRNQYPPMAGVAPLREAIADKIERLYGRRYDAATEITVTAGATQALLTAILCAVHP
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHCCC
GDEVIVIEPTYDSYLPSIELAGATPVFVTLNAPDYAIPFDKLAAAITPKTRAILINTPHN
CCEEEEEECCHHHHCCCEEECCCCEEEEEECCCCCCCCHHHHHHHCCCCCCEEEEECCCC
PTGTVWREADMRALEDIVRGTGLLIVSDEVYEHMVYDGARHESVARYPELAARSIIVSSF
CCCCEEHHHHHHHHHHHHCCCCEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHC
GKTFHVTGWKIGYVAAPAPLTAEFRKVHQFNVFTVNTPMQFGLADYLRDPEPYLTLPAFY
CCEEEECCEEEEEEECCCCCHHHHHHHHEEEEEEECCCHHHCHHHHHCCCCCCEECHHHH
QQKRDFFRAGLANTRFALLPCAGTYFQCVDYSAISDLPEAEFAKWLTTEIGVAAIPVSAF
HHHHHHHHHCCCCCCEEEEECCCCHHHHHCHHHHHCCCHHHHHHHHHHHCCHHEEEHHHH
YHEPHESGVVRFCFAKREDTLATALERLARL
HCCCCCCCEEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]