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The map label for this gene is flhA [H]

Identifier: 126454729

GI number: 126454729

Start: 3829734

End: 3831836

Strand: Reverse

Name: flhA [H]

Synonym: BURPS1106A_3924

Alternate gene names: 126454729

Gene position: 3831836-3829734 (Counterclockwise)

Preceding gene: 126454601

Following gene: 126454275

Centisome position: 96.07

GC content: 66.95

Gene sequence:

>2103_bases
ATGAACATGCCGGCCGGACTCCTCGGCAAGCGCGCGCAACTGTTCGCGGGCACGAACCTGCGCGCGCTCGCGGGTCCGAT
CCTCATCTGCATGATTCTGGGGATGATGATCCTGCCGCTGCCGCCGCTGCTGCTCGATCTGTTCTTCACGTTCAACATCG
CGCTGTCGGTGATGGTGCTGCTCGTCAGCATGTACACGATGAAGCCGCTCGATTTCGCCGCGTTCCCGAGCGTGCTGCTG
TTCTCGACGCTTTTGCGCCTGTCGCTGAACGTCGCGTCCACCCGCGTCGTGCTGCTCGAAGGCCACACGGGCCCGGACGC
GGCCGGCCAGGTGATCGAGGCGTTCGGCCACTTCCTCGTCGGCGGCAACTTCGCGGTCGGCATCGTCGTGTTCGTGATCC
TGATGATCATCAACTTCATGGTGATCACGAAGGGCGCGGGCCGGATCGCCGAAGTGTCCGCGCGCTTCACGCTCGACGCG
ATGCCCGGCAAGCAGATGGCGATCGACGCCGATCTGAACGCCGGCCTCATCAACGAAGAGCAGGCGAAGAAGCGCCGCCA
GTCGGTCGCGCAGGAAGCGGAGTTCTACGGCTCGATGGACGGCGCGTCGAAGTTCGTGCGCGGCGACGCGATCGCGGGCC
TGATCATCATGGCGATCAACGTGATCGGCGGCCTCATCGTCGGGATGGCCCAGCACGACATGAGCTTCGCCGCGGCGGGC
AAGAACTACACGCTGCTCACGATCGGCGACGGCCTCGTCGCGCAGATCCCGTCGCTCGTGATCTCGACCGCGGCCGGCGT
GATCGTCTCGCGCGTGGCGACCGACGAGGACATCGGCACGCAGCTCACCACGCAGCTCTTCACGAACCCGCGCGTGCTGA
TGATCACAGGCTCGATCATCGTGCTGATGGGGCTCATCCCGAACATGCCGCACTTCGCGTTTCTGCTGCTCGGCGGCGGC
GCGATCTGGCTGTCGCGCACGATGACCAAGCGCGAGGCCGCGAAGAAGGCGGCGGGCATGGTCGCGGAGATCGCGCCGCC
CGCCGCGCTGCCGGCCGACAGCCACGAGGCGACGTGGGAAGACGTGACGCTGATCGATCCGCTCGGCCTCGAAGTCGGCT
ACCGGCTGATTCCGCTCGTCGACAAGAACGCCGACGGCGAACTGCTCAAGCGGATCAAGAGCATCCGCAAGAAGTTCGCG
CAGGAAATCGGCTTCCTGCCGCCCGTCATTCACATCCGCGACAACCTCGAGCTGCGCCCGAACGCTTACCGGATCGCGCT
CAAGGGCGTCGAAGTCGGCACGGGCGAAGCGTATCCGGGCCAGTGGCTCGCGATCAATCCGGGCCAGGTGACGGCCGCGC
TGCCCGGCGCGCCGACGCAGGACCCGGCGTTCGGGCTGCCCGCCGTATGGATCGACACGGCGCTGCGCGAGCAGGCGCAG
GTGTACGGCTACACGGTCGTCGACGCGAGCACCGTCGTCGCGACGCACCTGAACCATCTCGTCGTCCAGCACGCGGCCGA
GCTGCTCGGCCGGCAGGAAGTGCAGGCGCTCATCGAGCGGACCGGCAAGGACGCGCCGTCGCTCGTCGAGGATCTGGTGC
CGAAGACGATCTCGCTCACGACGCTGCAGAAAGTGCTGCAGAACCTGCTCGACGAAGGCGTGCCGATCCGCGACATGCGC
ACGATCATCGAAGCCGTGTCCGAGCAGGCGGGCCGCATCACCGATCCTTACGATCTCACGGCCGCCGTGCGTCTTTCGCT
CGGCCGCGCGATCACGCAGCAGTGGTATCCGGGCGCGGGCGAGATGCAGGTGATGGGGCTCGACGCGAACCTCGAGCGCG
TGCTGTCGCAGGCGCTCGCCACCGGCGCGAATCCAGGCCTCGAACCGGGCCTCGCGCACTCGCTGCTCATCGGCACGCAA
GACGCGATGCTGCGCCAACAGAACATGGGGCTGCCGCCCGTGCTGCTCGTCCAGCACGCGCTGCGCGCGATGCTCGCGCG
CTTCCTGCGCCGCAGCCTGCCGCAATTGAAAGTGCTGTCCTACGCCGAAGTGCCGGACACGCGCACGATCAAAGTCGTTA
ACGTCATCGGGGGTACCGCTTGA

Upstream 100 bases:

>100_bases
ACGTGCCGGCCGAACTCGACAAGGGCGCGCACGTCGCGCCGCAAGACGAACGCGAAGAGGCCGAAGACGCGCTCGGCGGC
CGCGCCGCCGGAGGTGCCGC

Downstream 100 bases:

>100_bases
ACATTCGCAAATTCATTGGTCCGACGAGCCGCGACGCGCTGCGCCTCGTACGCGAAGCGATGGGCGCCGACGCGGCGGTA
CTGTCCAACCGGACGCTCGA

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 700; Mature: 700

Protein sequence:

>700_residues
MNMPAGLLGKRAQLFAGTNLRALAGPILICMILGMMILPLPPLLLDLFFTFNIALSVMVLLVSMYTMKPLDFAAFPSVLL
FSTLLRLSLNVASTRVVLLEGHTGPDAAGQVIEAFGHFLVGGNFAVGIVVFVILMIINFMVITKGAGRIAEVSARFTLDA
MPGKQMAIDADLNAGLINEEQAKKRRQSVAQEAEFYGSMDGASKFVRGDAIAGLIIMAINVIGGLIVGMAQHDMSFAAAG
KNYTLLTIGDGLVAQIPSLVISTAAGVIVSRVATDEDIGTQLTTQLFTNPRVLMITGSIIVLMGLIPNMPHFAFLLLGGG
AIWLSRTMTKREAAKKAAGMVAEIAPPAALPADSHEATWEDVTLIDPLGLEVGYRLIPLVDKNADGELLKRIKSIRKKFA
QEIGFLPPVIHIRDNLELRPNAYRIALKGVEVGTGEAYPGQWLAINPGQVTAALPGAPTQDPAFGLPAVWIDTALREQAQ
VYGYTVVDASTVVATHLNHLVVQHAAELLGRQEVQALIERTGKDAPSLVEDLVPKTISLTTLQKVLQNLLDEGVPIRDMR
TIIEAVSEQAGRITDPYDLTAAVRLSLGRAITQQWYPGAGEMQVMGLDANLERVLSQALATGANPGLEPGLAHSLLIGTQ
DAMLRQQNMGLPPVLLVQHALRAMLARFLRRSLPQLKVLSYAEVPDTRTIKVVNVIGGTA

Sequences:

>Translated_700_residues
MNMPAGLLGKRAQLFAGTNLRALAGPILICMILGMMILPLPPLLLDLFFTFNIALSVMVLLVSMYTMKPLDFAAFPSVLL
FSTLLRLSLNVASTRVVLLEGHTGPDAAGQVIEAFGHFLVGGNFAVGIVVFVILMIINFMVITKGAGRIAEVSARFTLDA
MPGKQMAIDADLNAGLINEEQAKKRRQSVAQEAEFYGSMDGASKFVRGDAIAGLIIMAINVIGGLIVGMAQHDMSFAAAG
KNYTLLTIGDGLVAQIPSLVISTAAGVIVSRVATDEDIGTQLTTQLFTNPRVLMITGSIIVLMGLIPNMPHFAFLLLGGG
AIWLSRTMTKREAAKKAAGMVAEIAPPAALPADSHEATWEDVTLIDPLGLEVGYRLIPLVDKNADGELLKRIKSIRKKFA
QEIGFLPPVIHIRDNLELRPNAYRIALKGVEVGTGEAYPGQWLAINPGQVTAALPGAPTQDPAFGLPAVWIDTALREQAQ
VYGYTVVDASTVVATHLNHLVVQHAAELLGRQEVQALIERTGKDAPSLVEDLVPKTISLTTLQKVLQNLLDEGVPIRDMR
TIIEAVSEQAGRITDPYDLTAAVRLSLGRAITQQWYPGAGEMQVMGLDANLERVLSQALATGANPGLEPGLAHSLLIGTQ
DAMLRQQNMGLPPVLLVQHALRAMLARFLRRSLPQLKVLSYAEVPDTRTIKVVNVIGGTA
>Mature_700_residues
MNMPAGLLGKRAQLFAGTNLRALAGPILICMILGMMILPLPPLLLDLFFTFNIALSVMVLLVSMYTMKPLDFAAFPSVLL
FSTLLRLSLNVASTRVVLLEGHTGPDAAGQVIEAFGHFLVGGNFAVGIVVFVILMIINFMVITKGAGRIAEVSARFTLDA
MPGKQMAIDADLNAGLINEEQAKKRRQSVAQEAEFYGSMDGASKFVRGDAIAGLIIMAINVIGGLIVGMAQHDMSFAAAG
KNYTLLTIGDGLVAQIPSLVISTAAGVIVSRVATDEDIGTQLTTQLFTNPRVLMITGSIIVLMGLIPNMPHFAFLLLGGG
AIWLSRTMTKREAAKKAAGMVAEIAPPAALPADSHEATWEDVTLIDPLGLEVGYRLIPLVDKNADGELLKRIKSIRKKFA
QEIGFLPPVIHIRDNLELRPNAYRIALKGVEVGTGEAYPGQWLAINPGQVTAALPGAPTQDPAFGLPAVWIDTALREQAQ
VYGYTVVDASTVVATHLNHLVVQHAAELLGRQEVQALIERTGKDAPSLVEDLVPKTISLTTLQKVLQNLLDEGVPIRDMR
TIIEAVSEQAGRITDPYDLTAAVRLSLGRAITQQWYPGAGEMQVMGLDANLERVLSQALATGANPGLEPGLAHSLLIGTQ
DAMLRQQNMGLPPVLLVQHALRAMLARFLRRSLPQLKVLSYAEVPDTRTIKVVNVIGGTA

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=681, Percent_Identity=65.9324522760646, Blast_Score=889, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 74947; Mature: 74947

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS00994 FHIPEP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMPAGLLGKRAQLFAGTNLRALAGPILICMILGMMILPLPPLLLDLFFTFNIALSVMVL
CCCCCCHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LVSMYTMKPLDFAAFPSVLLFSTLLRLSLNVASTRVVLLEGHTGPDAAGQVIEAFGHFLV
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHC
GGNFAVGIVVFVILMIINFMVITKGAGRIAEVSARFTLDAMPGKQMAIDADLNAGLINEE
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEEEEEECCCCCCEEEECCCCCCCCCHH
QAKKRRQSVAQEAEFYGSMDGASKFVRGDAIAGLIIMAINVIGGLIVGMAQHDMSFAAAG
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCC
KNYTLLTIGDGLVAQIPSLVISTAAGVIVSRVATDEDIGTQLTTQLFTNPRVLMITGSII
CCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEECHHH
VLMGLIPNMPHFAFLLLGGGAIWLSRTMTKREAAKKAAGMVAEIAPPAALPADSHEATWE
HHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCC
DVTLIDPLGLEVGYRLIPLVDKNADGELLKRIKSIRKKFAQEIGFLPPVIHIRDNLELRP
CEEEECCCCHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEECC
NAYRIALKGVEVGTGEAYPGQWLAINPGQVTAALPGAPTQDPAFGLPAVWIDTALREQAQ
CEEEEEEEEEEECCCCCCCCCEEEECCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHH
VYGYTVVDASTVVATHLNHLVVQHAAELLGRQEVQALIERTGKDAPSLVEDLVPKTISLT
HHCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHH
TLQKVLQNLLDEGVPIRDMRTIIEAVSEQAGRITDPYDLTAAVRLSLGRAITQQWYPGAG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
EMQVMGLDANLERVLSQALATGANPGLEPGLAHSLLIGTQDAMLRQQNMGLPPVLLVQHA
CEEEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHCCCHHHHHHHHCCCCCHHHHHHHH
LRAMLARFLRRSLPQLKVLSYAEVPDTRTIKVVNVIGGTA
HHHHHHHHHHHCCCCEEHHHHCCCCCCCEEEEEEECCCCC
>Mature Secondary Structure
MNMPAGLLGKRAQLFAGTNLRALAGPILICMILGMMILPLPPLLLDLFFTFNIALSVMVL
CCCCCCHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LVSMYTMKPLDFAAFPSVLLFSTLLRLSLNVASTRVVLLEGHTGPDAAGQVIEAFGHFLV
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHC
GGNFAVGIVVFVILMIINFMVITKGAGRIAEVSARFTLDAMPGKQMAIDADLNAGLINEE
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEEEEEECCCCCCEEEECCCCCCCCCHH
QAKKRRQSVAQEAEFYGSMDGASKFVRGDAIAGLIIMAINVIGGLIVGMAQHDMSFAAAG
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCC
KNYTLLTIGDGLVAQIPSLVISTAAGVIVSRVATDEDIGTQLTTQLFTNPRVLMITGSII
CCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEECHHH
VLMGLIPNMPHFAFLLLGGGAIWLSRTMTKREAAKKAAGMVAEIAPPAALPADSHEATWE
HHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCC
DVTLIDPLGLEVGYRLIPLVDKNADGELLKRIKSIRKKFAQEIGFLPPVIHIRDNLELRP
CEEEECCCCHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEECC
NAYRIALKGVEVGTGEAYPGQWLAINPGQVTAALPGAPTQDPAFGLPAVWIDTALREQAQ
CEEEEEEEEEEECCCCCCCCCEEEECCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHH
VYGYTVVDASTVVATHLNHLVVQHAAELLGRQEVQALIERTGKDAPSLVEDLVPKTISLT
HHCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHH
TLQKVLQNLLDEGVPIRDMRTIIEAVSEQAGRITDPYDLTAAVRLSLGRAITQQWYPGAG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
EMQVMGLDANLERVLSQALATGANPGLEPGLAHSLLIGTQDAMLRQQNMGLPPVLLVQHA
CEEEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHCCCHHHHHHHHCCCCCHHHHHHHH
LRAMLARFLRRSLPQLKVLSYAEVPDTRTIKVVNVIGGTA
HHHHHHHHHHHCCCCEEHHHHCCCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]