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The map label for this gene is atoC [H]

Identifier: 126454405

GI number: 126454405

Start: 2847176

End: 2849050

Strand: Direct

Name: atoC [H]

Synonym: BURPS1106A_2901

Alternate gene names: 126454405

Gene position: 2847176-2849050 (Clockwise)

Preceding gene: 126452075

Following gene: 126453089

Centisome position: 71.39

GC content: 70.35

Gene sequence:

>1875_bases
ATGTTTCCCGGGCGCCGCGCAATGCGCGCCGCATGCATCGTCGCGCACACGTCCGTCCCCCGAACGATTGCCCACGCATC
GCCGCGACGCCGGCGCGGCTCGCTCGCCGAACGACTTCCTCGCCGCCCAGTCGCGTCGGATGCGTCGGATGCGTCGGATG
CGTCGGTCGCATCGGTCGCATCGGTCGCATCGGTCGCATCGGTCGCGTCGGTCGCATCGGTCGCGTCGGTCGCGTCGGTC
GCGTCGGTCGCATCGGTCGCGTCGGTCGCGTCGCCCCCATCAGTCGCCCAACTCGCATCGGCCGCACCCTGCGCGGCAAC
GACGCCCGCGGCGCGCGCCGGCGCGCCCACCTCGAACTCCGCTCGCCGCGCTCGCCCCGACACGTTCCGAACAACATCCC
AGCTGAGGTGCATCGTGCCAGACTTCCGCCCCCCTTCCGATTGCGCGCCGCCCGGCCATGCCGCGCAGCGCTCCGCCTCA
CCGGCCGATGCGGCCGCGCGCCAGCTCGTCTACCTGTCGCGCACGCCCGACACGACGCTCGTCGCGCACCTGCGCGCACG
ACGCTGGAACGTGCACGTCGCGCGCTCCGCGAACGAAGCGGCGCGGCGCGTGAAGCCGAATCAGCCGCAGGCCGGCATCG
CCGATCTCGACGGCTTCGCGCCGCGCGAGTTGCCGACGCTCGAAGCGGTGTTGCGCCAGCAGCAGGTCGGCTGGATCGCG
CTCGCGGGTGACACGCGCATCAACGATCCCGACGTGCGCCGGCTGATTCGCCAGTACTGCTTCGACTACATGCAGGGCCT
GCCCCCGCACGAGACGATTGATTATCTCGTCGGCCATGCCTACGGGATGGTCGCGCTGTGCGATCTCGACGTCACGGCGG
GCGCCGCCGCGACGGGCGACGAGATGGTGGGCGCGTGCGACGCGATGCAGCAGTTGTTCCGGACGATCCGCAAGGTCGCC
GCGACCGACGCGACCGTGTTCATCTCCGGCGAATCGGGCACCGGCAAGGAGCTGACCGCGCTCGCGATCCACGAGCGCTC
CGAGCGCCGCAAGGCGCCGTTCGTCGCGATCAACTGCGGCGCGATTCCGAATCATCTGCTGCAATCCGAACTGTTCGGCT
ACGAGCGCGGCGCATTCACGGGCGCGAGCCAGCGCAAGGTCGGCCGTGTCGAAGCGGCGGACGGCGGCACGCTGTTTCTC
GACGAAATCGGCGACATGCCGCTCGAAAGCCAGGCGAGCATGCTGCGCTTCCTGCAGGAAGGCAAGATCGAACGGCTCGG
CGGGCACGAGTCGATTCCGGTCGACGTGCGGATCATCTCCGCGACGCACGTCGATCTCGACGCGGCGATGCGCGAAGGCC
GCTTTCGCGACGACCTGTACCACCGGCTGTGCGTGCTGAAGCTCGACGAGCCGCCGTTGCGCGCGCGCGGCAAGGACATC
GAAATCCTCGCGCATCACATCCTGCATCAGTTCAGGAGCGACGGCGCGCGCCGCATTCACGGCTTCACGTCGTGCGCGAT
CGAAGCGATGTACAACTATCACTGGCCCGGCAACGTGCGCGAGCTGATCAACCGGATCCGGCGCGCGATCGTGATGTCGG
ACAGCCGGCAACTGTCGGCCGCCGACCTCGATCTCGCGCCGTTCGCCGCGCGCCAGGCGACGACGCTCGCCGAAGCGCGC
GAGCGCGCCGAGCGCCGGACGATCGAGGCGTCGCTGCTGCGGCATCGCAACCGTCTGACCGAAGCGGCGGCGGAACTCGG
CGTGTCGCGCGCGACGCTGTATCGGCTGATGGTGTCGCACGGCCTGCGCGAACTGTCGTGGGGCGCGCAACGCGCCGGCG
CGAGCGACGCGGACGACGAGGCCGGGCCCGCATGA

Upstream 100 bases:

>100_bases
GCGCGACGCGCGCGCGTTCGCCGCATCGACATCCGGCCGAACCGCGCGGATCGCGGCGGCGCGCCGTGGCGGCGAGCGGC
ATGGCGCCGCCGACAGGCCG

Downstream 100 bases:

>100_bases
TGCGCGCGCGGCATGCGCACGTGCTGCTCGCGTGCGGCACGTGACACGTCGGCCGCCGCGAGACGCGCGGGAGCGCGCCC
GTCGAGCCCGCGCGACGCGT

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 624; Mature: 624

Protein sequence:

>624_residues
MFPGRRAMRAACIVAHTSVPRTIAHASPRRRRGSLAERLPRRPVASDASDASDASVASVASVASVASVASVASVASVASV
ASVASVASVASPPSVAQLASAAPCAATTPAARAGAPTSNSARRARPDTFRTTSQLRCIVPDFRPPSDCAPPGHAAQRSAS
PADAAARQLVYLSRTPDTTLVAHLRARRWNVHVARSANEAARRVKPNQPQAGIADLDGFAPRELPTLEAVLRQQQVGWIA
LAGDTRINDPDVRRLIRQYCFDYMQGLPPHETIDYLVGHAYGMVALCDLDVTAGAAATGDEMVGACDAMQQLFRTIRKVA
ATDATVFISGESGTGKELTALAIHERSERRKAPFVAINCGAIPNHLLQSELFGYERGAFTGASQRKVGRVEAADGGTLFL
DEIGDMPLESQASMLRFLQEGKIERLGGHESIPVDVRIISATHVDLDAAMREGRFRDDLYHRLCVLKLDEPPLRARGKDI
EILAHHILHQFRSDGARRIHGFTSCAIEAMYNYHWPGNVRELINRIRRAIVMSDSRQLSAADLDLAPFAARQATTLAEAR
ERAERRTIEASLLRHRNRLTEAAAELGVSRATLYRLMVSHGLRELSWGAQRAGASDADDEAGPA

Sequences:

>Translated_624_residues
MFPGRRAMRAACIVAHTSVPRTIAHASPRRRRGSLAERLPRRPVASDASDASDASVASVASVASVASVASVASVASVASV
ASVASVASVASPPSVAQLASAAPCAATTPAARAGAPTSNSARRARPDTFRTTSQLRCIVPDFRPPSDCAPPGHAAQRSAS
PADAAARQLVYLSRTPDTTLVAHLRARRWNVHVARSANEAARRVKPNQPQAGIADLDGFAPRELPTLEAVLRQQQVGWIA
LAGDTRINDPDVRRLIRQYCFDYMQGLPPHETIDYLVGHAYGMVALCDLDVTAGAAATGDEMVGACDAMQQLFRTIRKVA
ATDATVFISGESGTGKELTALAIHERSERRKAPFVAINCGAIPNHLLQSELFGYERGAFTGASQRKVGRVEAADGGTLFL
DEIGDMPLESQASMLRFLQEGKIERLGGHESIPVDVRIISATHVDLDAAMREGRFRDDLYHRLCVLKLDEPPLRARGKDI
EILAHHILHQFRSDGARRIHGFTSCAIEAMYNYHWPGNVRELINRIRRAIVMSDSRQLSAADLDLAPFAARQATTLAEAR
ERAERRTIEASLLRHRNRLTEAAAELGVSRATLYRLMVSHGLRELSWGAQRAGASDADDEAGPA
>Mature_624_residues
MFPGRRAMRAACIVAHTSVPRTIAHASPRRRRGSLAERLPRRPVASDASDASDASVASVASVASVASVASVASVASVASV
ASVASVASVASPPSVAQLASAAPCAATTPAARAGAPTSNSARRARPDTFRTTSQLRCIVPDFRPPSDCAPPGHAAQRSAS
PADAAARQLVYLSRTPDTTLVAHLRARRWNVHVARSANEAARRVKPNQPQAGIADLDGFAPRELPTLEAVLRQQQVGWIA
LAGDTRINDPDVRRLIRQYCFDYMQGLPPHETIDYLVGHAYGMVALCDLDVTAGAAATGDEMVGACDAMQQLFRTIRKVA
ATDATVFISGESGTGKELTALAIHERSERRKAPFVAINCGAIPNHLLQSELFGYERGAFTGASQRKVGRVEAADGGTLFL
DEIGDMPLESQASMLRFLQEGKIERLGGHESIPVDVRIISATHVDLDAAMREGRFRDDLYHRLCVLKLDEPPLRARGKDI
EILAHHILHQFRSDGARRIHGFTSCAIEAMYNYHWPGNVRELINRIRRAIVMSDSRQLSAADLDLAPFAARQATTLAEAR
ERAERRTIEASLLRHRNRLTEAAAELGVSRATLYRLMVSHGLRELSWGAQRAGASDADDEAGPA

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=429, Percent_Identity=39.3939393939394, Blast_Score=262, Evalue=4e-71,
Organism=Escherichia coli, GI1788550, Length=304, Percent_Identity=46.7105263157895, Blast_Score=260, Evalue=2e-70,
Organism=Escherichia coli, GI1788905, Length=295, Percent_Identity=45.0847457627119, Blast_Score=244, Evalue=1e-65,
Organism=Escherichia coli, GI1790299, Length=333, Percent_Identity=43.5435435435435, Blast_Score=241, Evalue=8e-65,
Organism=Escherichia coli, GI87082117, Length=325, Percent_Identity=42.4615384615385, Blast_Score=240, Evalue=2e-64,
Organism=Escherichia coli, GI1789233, Length=322, Percent_Identity=42.5465838509317, Blast_Score=240, Evalue=2e-64,
Organism=Escherichia coli, GI1789087, Length=308, Percent_Identity=42.5324675324675, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI87082152, Length=331, Percent_Identity=41.6918429003021, Blast_Score=223, Evalue=4e-59,
Organism=Escherichia coli, GI1786524, Length=316, Percent_Identity=41.7721518987342, Blast_Score=218, Evalue=9e-58,
Organism=Escherichia coli, GI87081872, Length=322, Percent_Identity=36.9565217391304, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI1787583, Length=323, Percent_Identity=34.0557275541796, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI87081858, Length=295, Percent_Identity=32.2033898305085, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1789828, Length=218, Percent_Identity=33.0275229357798, Blast_Score=114, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 67263; Mature: 67263

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFPGRRAMRAACIVAHTSVPRTIAHASPRRRRGSLAERLPRRPVASDASDASDASVASVA
CCCCHHHHHHHHHHEECCCCHHHHHCCCHHHCCCHHHHCCCCCCCCCCCCCCHHHHHHHH
SVASVASVASVASVASVASVASVASVASVASPPSVAQLASAAPCAATTPAARAGAPTSNS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCHHCCCCCCCC
ARRARPDTFRTTSQLRCIVPDFRPPSDCAPPGHAAQRSASPADAAARQLVYLSRTPDTTL
CCCCCCCHHCCCCCCEEECCCCCCCCCCCCCCCHHHCCCCCHHHHHHHEEEEECCCCHHH
VAHLRARRWNVHVARSANEAARRVKPNQPQAGIADLDGFAPRELPTLEAVLRQQQVGWIA
HHHHHHHHCEEEEECCHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEE
LAGDTRINDPDVRRLIRQYCFDYMQGLPPHETIDYLVGHAYGMVALCDLDVTAGAAATGD
EECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCEEEEEECCCCCCCCCCCH
EMVGACDAMQQLFRTIRKVAATDATVFISGESGTGKELTALAIHERSERRKAPFVAINCG
HHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEHHHHHHHHHHCCCCEEEEECC
AIPNHLLQSELFGYERGAFTGASQRKVGRVEAADGGTLFLDEIGDMPLESQASMLRFLQE
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCEEEHHHHCCCCCHHHHHHHHHHHH
GKIERLGGHESIPVDVRIISATHVDLDAAMREGRFRDDLYHRLCVLKLDEPPLRARGKDI
CCHHHCCCCCCCCEEEEEEEEECCCHHHHHHCCCCHHHHHHHEEEEECCCCCCCCCCCHH
EILAHHILHQFRSDGARRIHGFTSCAIEAMYNYHWPGNVRELINRIRRAIVMSDSRQLSA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
ADLDLAPFAARQATTLAEARERAERRTIEASLLRHRNRLTEAAAELGVSRATLYRLMVSH
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
GLRELSWGAQRAGASDADDEAGPA
CHHHHHCCHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MFPGRRAMRAACIVAHTSVPRTIAHASPRRRRGSLAERLPRRPVASDASDASDASVASVA
CCCCHHHHHHHHHHEECCCCHHHHHCCCHHHCCCHHHHCCCCCCCCCCCCCCHHHHHHHH
SVASVASVASVASVASVASVASVASVASVASPPSVAQLASAAPCAATTPAARAGAPTSNS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCHHCCCCCCCC
ARRARPDTFRTTSQLRCIVPDFRPPSDCAPPGHAAQRSASPADAAARQLVYLSRTPDTTL
CCCCCCCHHCCCCCCEEECCCCCCCCCCCCCCCHHHCCCCCHHHHHHHEEEEECCCCHHH
VAHLRARRWNVHVARSANEAARRVKPNQPQAGIADLDGFAPRELPTLEAVLRQQQVGWIA
HHHHHHHHCEEEEECCHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEE
LAGDTRINDPDVRRLIRQYCFDYMQGLPPHETIDYLVGHAYGMVALCDLDVTAGAAATGD
EECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCEEEEEECCCCCCCCCCCH
EMVGACDAMQQLFRTIRKVAATDATVFISGESGTGKELTALAIHERSERRKAPFVAINCG
HHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEHHHHHHHHHHCCCCEEEEECC
AIPNHLLQSELFGYERGAFTGASQRKVGRVEAADGGTLFLDEIGDMPLESQASMLRFLQE
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCEEEHHHHCCCCCHHHHHHHHHHHH
GKIERLGGHESIPVDVRIISATHVDLDAAMREGRFRDDLYHRLCVLKLDEPPLRARGKDI
CCHHHCCCCCCCCEEEEEEEEECCCHHHHHHCCCCHHHHHHHEEEEECCCCCCCCCCCHH
EILAHHILHQFRSDGARRIHGFTSCAIEAMYNYHWPGNVRELINRIRRAIVMSDSRQLSA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
ADLDLAPFAARQATTLAEARERAERRTIEASLLRHRNRLTEAAAELGVSRATLYRLMVSH
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
GLRELSWGAQRAGASDADDEAGPA
CHHHHHCCHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]