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The map label for this gene is adiA [H]

Identifier: 126454145

GI number: 126454145

Start: 1041912

End: 1044191

Strand: Direct

Name: adiA [H]

Synonym: BURPS1106A_1064

Alternate gene names: 126454145

Gene position: 1041912-1044191 (Clockwise)

Preceding gene: 126451751

Following gene: 126455025

Centisome position: 26.12

GC content: 64.91

Gene sequence:

>2280_bases
ATGAAGTTTCGTTTTCCCGTCGTCATCATCGACGAAGATTTCCGCTCCGAGAACATCTCGGGCTCCGGCATCCGGGCGTT
GGCGGAGGCGATCGAGAAAGAAGGCGTCGAGGTGCTCGGCCTGACGAGCTACGGCGATCTGACGTCGTTCGCGCAGCAGT
CGAGCCGCGCGTCGTGCTTCATCCTGTCGATCGACGACGACGAACTGATGCTCGGCGAGCTCGGCGCGGACGGCGAGCTG
CCCGAGCTCGCGACCGCGATCATCGAGCTGCGCGCGTTCGTCGCCGAAGTGCGCCGCCGCAACGCGGACATCCCGATCTT
CCTGTACGGCGAGACGCGCACGTCGCGCCATCTGCCGAACGACATCCTGCGCGAGCTGCACGGCTTCATCCACATGTTCG
AGGACACGCCGGAGTTCGTCGCGCGCCACATCATCCGCGAGGCGAAGGTCTACCTCGATTCGCTCGCGCCGCCGTTCTTC
AAGGAGCTCGTCAAGTACGCGGACGAAGGCTCGTACTCGTGGCACTGCCCGGGGCACTCCGGCGGCGTCGCGTTCCTGAA
GAACCCGCTCGGCCAGATGTTCCACCAGTTCTTCGGCGAGAACATGCTGCGCGCGGACGTGTGCAACGCGGTCGACGAGC
TTGGCCAGTTGCTCGACCACACGGGGCCCGTGGCCGCGTCCGAGCGCAACGCCGCGCGGATCTTCAGCGCCGATCACCTG
TTCTTCGTGACGAACGGCACGTCGACGTCGAACAAGATCGTCTGGCACGCGACGGTCGCGCCGGGCGACATCGTGCTCGT
CGATCGCAACTGCCACAAGTCGATCCTGCACGCGATCACGATGACGCACGCGATTCCGGTGTTCCTCACGCCGACGCGCA
ACCACTTCGGCATCATCGGGCCGATTCCGCGCGACGAGTTCAAGCCGGAGAACATCCGCAAGAAGATCGAGGCGAACCCG
TTCGCGCGCGAGGCGCTCAGGAAGAATCCGAACGCGAAGCCGCGGATCCTCACGATCACGCAGAGCACGTACGACGGCGT
CGTCTACAACGTCGAGCAGATCAAGGATCTGCTCGGCGATCTCGTCGACACGCTGCACTTCGACGAAGCGTGGCTGCCGC
ACGCCGAGTTCCATCCGTTCTACCAGGACATGCACGCGATCGGCGCGGGCCGCCCGCGCACGGGCGCGCTCGTGTTCGCG
ACGCACTCGACGCACAAGCTGCTCGCGGGCATCTCGCAGGCCTCGCAGATCGTGGTGCAGGATTCGGAGAACCGCACGTT
CGACAAGCATCGCTTCAACGAGGCGTACCTGATGCACACGTCGACGAGCCCGCAATACGCGATCATCGCGTCGTGCGATG
TCGCGGCCGCGATGATGGAGCCGCCGGGCGGCACCGCGCTCGTCGAGGAATCGATCGCCGAGGCGATCGACTTTCGCCGC
GCGATGCGCAAGGTGGACGCCGAGTACGGCGACGACTGGTTCTTCAGCGTGTGGGGCCCGGACAACCTGTCGGAGGAGGG
AATCGGCTCGCGCGCCGACTGGCTGCTCAAGCCGAACGACCGCTGGCACGGCTTCGGCCCGCTCGCGCCGGGCTTCAACA
TGCTCGACCCGATCAAGGCGACGATCATCACGCCGGGGCTCGACGTCGACGGCGAGTTCGGCGAAACGGGCATTCCGGCC
GCGATCGTTACCAAGTATCTGGCCGAGCACGGGATCATCGTCGAGAAGACGGGCCTGTACTCGTTCTTCATCATGTTCAC
GATCGGCATCACGAAGGGCCGCTGGAACTCGATGGTCACCGAGCTGCAGCAGTTCAAGGACGACTACGACAACAACCAGC
CGCTCTGGCGCGTGCTGCCCGAGTTCGTCGCGCAGTATCCGCTCTACGAGCGCGTCGGCCTGCGCGATCTCTGCACGCAG
ATCCACGACGTGTACCGCGCGAACGACATCGCGCGGCTCACGACTGAGATGTACCTGTCGAACATGGAGCCGGCGATGAA
GCCGTCCGACGCGTTCGCGAAGCTCGCGCACCGCGAGATCGACCGCGTGCCGCTCGACGAGCTCGAAGGACGCGTGACGA
GCATCCTGCTCACGCCGTATCCGCCGGGCATTCCGCTGTTGATCCCGGGCGAGCGCTTCAACAAGACGATCGTCAACTAC
CTGCGGTTCGCGCGCGATTTCAACGAGCGCTTCCCGGGCTTTCACACGGACATCCACGGCCTCGTCGCCGAAGAGATGAA
CGGCCGCATCGAGTACTACGTCGACTGCGTGCGCGATTGA

Upstream 100 bases:

>100_bases
TGCTTGCATATCGGTCTGACCTATCGCCAGTCCGGGTGACCGCTGCGCCGGGGCATGAACAGCCCCCCGCGCCGCGGTCG
TTCTTTTTGGAGAATCGCCC

Downstream 100 bases:

>100_bases
CGATGACGGCAGTCCGCAAGACGCTCGTGCGTTTCGCCGCCGCCGCGCTCGCCGGCTGGCTCGCGGCGGCGGCGGCGGGC
GCGGCGCACGCCGAGGTCGC

Product: Orn/Lys/Arg decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 759; Mature: 759

Protein sequence:

>759_residues
MKFRFPVVIIDEDFRSENISGSGIRALAEAIEKEGVEVLGLTSYGDLTSFAQQSSRASCFILSIDDDELMLGELGADGEL
PELATAIIELRAFVAEVRRRNADIPIFLYGETRTSRHLPNDILRELHGFIHMFEDTPEFVARHIIREAKVYLDSLAPPFF
KELVKYADEGSYSWHCPGHSGGVAFLKNPLGQMFHQFFGENMLRADVCNAVDELGQLLDHTGPVAASERNAARIFSADHL
FFVTNGTSTSNKIVWHATVAPGDIVLVDRNCHKSILHAITMTHAIPVFLTPTRNHFGIIGPIPRDEFKPENIRKKIEANP
FAREALRKNPNAKPRILTITQSTYDGVVYNVEQIKDLLGDLVDTLHFDEAWLPHAEFHPFYQDMHAIGAGRPRTGALVFA
THSTHKLLAGISQASQIVVQDSENRTFDKHRFNEAYLMHTSTSPQYAIIASCDVAAAMMEPPGGTALVEESIAEAIDFRR
AMRKVDAEYGDDWFFSVWGPDNLSEEGIGSRADWLLKPNDRWHGFGPLAPGFNMLDPIKATIITPGLDVDGEFGETGIPA
AIVTKYLAEHGIIVEKTGLYSFFIMFTIGITKGRWNSMVTELQQFKDDYDNNQPLWRVLPEFVAQYPLYERVGLRDLCTQ
IHDVYRANDIARLTTEMYLSNMEPAMKPSDAFAKLAHREIDRVPLDELEGRVTSILLTPYPPGIPLLIPGERFNKTIVNY
LRFARDFNERFPGFHTDIHGLVAEEMNGRIEYYVDCVRD

Sequences:

>Translated_759_residues
MKFRFPVVIIDEDFRSENISGSGIRALAEAIEKEGVEVLGLTSYGDLTSFAQQSSRASCFILSIDDDELMLGELGADGEL
PELATAIIELRAFVAEVRRRNADIPIFLYGETRTSRHLPNDILRELHGFIHMFEDTPEFVARHIIREAKVYLDSLAPPFF
KELVKYADEGSYSWHCPGHSGGVAFLKNPLGQMFHQFFGENMLRADVCNAVDELGQLLDHTGPVAASERNAARIFSADHL
FFVTNGTSTSNKIVWHATVAPGDIVLVDRNCHKSILHAITMTHAIPVFLTPTRNHFGIIGPIPRDEFKPENIRKKIEANP
FAREALRKNPNAKPRILTITQSTYDGVVYNVEQIKDLLGDLVDTLHFDEAWLPHAEFHPFYQDMHAIGAGRPRTGALVFA
THSTHKLLAGISQASQIVVQDSENRTFDKHRFNEAYLMHTSTSPQYAIIASCDVAAAMMEPPGGTALVEESIAEAIDFRR
AMRKVDAEYGDDWFFSVWGPDNLSEEGIGSRADWLLKPNDRWHGFGPLAPGFNMLDPIKATIITPGLDVDGEFGETGIPA
AIVTKYLAEHGIIVEKTGLYSFFIMFTIGITKGRWNSMVTELQQFKDDYDNNQPLWRVLPEFVAQYPLYERVGLRDLCTQ
IHDVYRANDIARLTTEMYLSNMEPAMKPSDAFAKLAHREIDRVPLDELEGRVTSILLTPYPPGIPLLIPGERFNKTIVNY
LRFARDFNERFPGFHTDIHGLVAEEMNGRIEYYVDCVRD
>Mature_759_residues
MKFRFPVVIIDEDFRSENISGSGIRALAEAIEKEGVEVLGLTSYGDLTSFAQQSSRASCFILSIDDDELMLGELGADGEL
PELATAIIELRAFVAEVRRRNADIPIFLYGETRTSRHLPNDILRELHGFIHMFEDTPEFVARHIIREAKVYLDSLAPPFF
KELVKYADEGSYSWHCPGHSGGVAFLKNPLGQMFHQFFGENMLRADVCNAVDELGQLLDHTGPVAASERNAARIFSADHL
FFVTNGTSTSNKIVWHATVAPGDIVLVDRNCHKSILHAITMTHAIPVFLTPTRNHFGIIGPIPRDEFKPENIRKKIEANP
FAREALRKNPNAKPRILTITQSTYDGVVYNVEQIKDLLGDLVDTLHFDEAWLPHAEFHPFYQDMHAIGAGRPRTGALVFA
THSTHKLLAGISQASQIVVQDSENRTFDKHRFNEAYLMHTSTSPQYAIIASCDVAAAMMEPPGGTALVEESIAEAIDFRR
AMRKVDAEYGDDWFFSVWGPDNLSEEGIGSRADWLLKPNDRWHGFGPLAPGFNMLDPIKATIITPGLDVDGEFGETGIPA
AIVTKYLAEHGIIVEKTGLYSFFIMFTIGITKGRWNSMVTELQQFKDDYDNNQPLWRVLPEFVAQYPLYERVGLRDLCTQ
IHDVYRANDIARLTTEMYLSNMEPAMKPSDAFAKLAHREIDRVPLDELEGRVTSILLTPYPPGIPLLIPGERFNKTIVNY
LRFARDFNERFPGFHTDIHGLVAEEMNGRIEYYVDCVRD

Specific function: ADC can be found in two forms:biodegradative and biosynthetic. The biodegradative form may play a role in regulating pH by consuming proteins [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI221142684, Length=777, Percent_Identity=37.3230373230373, Blast_Score=538, Evalue=1e-154,
Organism=Escherichia coli, GI1790573, Length=741, Percent_Identity=36.9770580296896, Blast_Score=496, Evalue=1e-141,
Organism=Escherichia coli, GI1786384, Length=726, Percent_Identity=37.1900826446281, Blast_Score=491, Evalue=1e-140,
Organism=Escherichia coli, GI1786909, Length=672, Percent_Identity=32.8869047619048, Blast_Score=370, Evalue=1e-103,
Organism=Escherichia coli, GI87082193, Length=682, Percent_Identity=34.0175953079179, Blast_Score=368, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005308
- InterPro:   IPR011193
- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C; PF03709 OKR_DC_1_N [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 85418; Mature: 85418

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFRFPVVIIDEDFRSENISGSGIRALAEAIEKEGVEVLGLTSYGDLTSFAQQSSRASCF
CCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCEEE
ILSIDDDELMLGELGADGELPELATAIIELRAFVAEVRRRNADIPIFLYGETRTSRHLPN
EEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCH
DILRELHGFIHMFEDTPEFVARHIIREAKVYLDSLAPPFFKELVKYADEGSYSWHCPGHS
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEECCCCC
GGVAFLKNPLGQMFHQFFGENMLRADVCNAVDELGQLLDHTGPVAASERNAARIFSADHL
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCEE
FFVTNGTSTSNKIVWHATVAPGDIVLVDRNCHKSILHAITMTHAIPVFLTPTRNHFGIIG
EEEECCCCCCCEEEEEEEECCCCEEEECCCHHHHHHHHHHHHHCCEEEEECCCCCCEEEC
PIPRDEFKPENIRKKIEANPFAREALRKNPNAKPRILTITQSTYDGVVYNVEQIKDLLGD
CCCCCCCCCHHHHHHHCCCHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHH
LVDTLHFDEAWLPHAEFHPFYQDMHAIGAGRPRTGALVFATHSTHKLLAGISQASQIVVQ
HHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHCEEEEE
DSENRTFDKHRFNEAYLMHTSTSPQYAIIASCDVAAAMMEPPGGTALVEESIAEAIDFRR
CCCCCCCHHHCCCCEEEEEECCCCCEEEEEECHHHHHHCCCCCCHHHHHHHHHHHHHHHH
AMRKVDAEYGDDWFFSVWGPDNLSEEGIGSRADWLLKPNDRWHGFGPLAPGFNMLDPIKA
HHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCC
TIITPGLDVDGEFGETGIPAAIVTKYLAEHGIIVEKTGLYSFFIMFTIGITKGRWNSMVT
EEECCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCCHHHHHHH
ELQQFKDDYDNNQPLWRVLPEFVAQYPLYERVGLRDLCTQIHDVYRANDIARLTTEMYLS
HHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
NMEPAMKPSDAFAKLAHREIDRVPLDELEGRVTSILLTPYPPGIPLLIPGERFNKTIVNY
CCCCCCCCHHHHHHHHHHHHCCCCHHHHCCCEEEEEECCCCCCCCEEECCHHHHHHHHHH
LRFARDFNERFPGFHTDIHGLVAEEMNGRIEYYVDCVRD
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEEEEECC
>Mature Secondary Structure
MKFRFPVVIIDEDFRSENISGSGIRALAEAIEKEGVEVLGLTSYGDLTSFAQQSSRASCF
CCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCEEE
ILSIDDDELMLGELGADGELPELATAIIELRAFVAEVRRRNADIPIFLYGETRTSRHLPN
EEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCH
DILRELHGFIHMFEDTPEFVARHIIREAKVYLDSLAPPFFKELVKYADEGSYSWHCPGHS
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEECCCCC
GGVAFLKNPLGQMFHQFFGENMLRADVCNAVDELGQLLDHTGPVAASERNAARIFSADHL
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCEE
FFVTNGTSTSNKIVWHATVAPGDIVLVDRNCHKSILHAITMTHAIPVFLTPTRNHFGIIG
EEEECCCCCCCEEEEEEEECCCCEEEECCCHHHHHHHHHHHHHCCEEEEECCCCCCEEEC
PIPRDEFKPENIRKKIEANPFAREALRKNPNAKPRILTITQSTYDGVVYNVEQIKDLLGD
CCCCCCCCCHHHHHHHCCCHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHH
LVDTLHFDEAWLPHAEFHPFYQDMHAIGAGRPRTGALVFATHSTHKLLAGISQASQIVVQ
HHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHCEEEEE
DSENRTFDKHRFNEAYLMHTSTSPQYAIIASCDVAAAMMEPPGGTALVEESIAEAIDFRR
CCCCCCCHHHCCCCEEEEEECCCCCEEEEEECHHHHHHCCCCCCHHHHHHHHHHHHHHHH
AMRKVDAEYGDDWFFSVWGPDNLSEEGIGSRADWLLKPNDRWHGFGPLAPGFNMLDPIKA
HHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCC
TIITPGLDVDGEFGETGIPAAIVTKYLAEHGIIVEKTGLYSFFIMFTIGITKGRWNSMVT
EEECCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCCHHHHHHH
ELQQFKDDYDNNQPLWRVLPEFVAQYPLYERVGLRDLCTQIHDVYRANDIARLTTEMYLS
HHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
NMEPAMKPSDAFAKLAHREIDRVPLDELEGRVTSILLTPYPPGIPLLIPGERFNKTIVNY
CCCCCCCCHHHHHHHHHHHHCCCCHHHHCCCEEEEEECCCCCCCCEEECCHHHHHHHHHH
LRFARDFNERFPGFHTDIHGLVAEEMNGRIEYYVDCVRD
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8383109; 7610040; 9278503; 2830169; 4204273 [H]