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The map label for this gene is tldD [H]

Identifier: 126453927

GI number: 126453927

Start: 3246413

End: 3247909

Strand: Direct

Name: tldD [H]

Synonym: BURPS1106A_3323

Alternate gene names: 126453927

Gene position: 3246413-3247909 (Clockwise)

Preceding gene: 126454542

Following gene: 126453984

Centisome position: 81.4

GC content: 69.74

Gene sequence:

>1497_bases
ATGAACATCATCGAACCCGGCATCCCCCAAGGGGACTTCCTTCAGGGCGCCCGCAACCTCTCGCTCGCGAAGGACATCCT
GCTCACGCCGTACGGCCTCGACGAAGCCCTTCTCACGCGCACGCTCGCCGATATCTTCACGCATCGCGTCGACTACGCGG
ATCTGTACTTCCAGGCCACCCGCAGCGAAGCGTGGAGCCTCGAGGAAGGCATCGTCAAGTCGGGCAGCTTCAGCATCGAC
CAGGGCGTCGGCGTGCGCGCGGTCGCCGGCGAGCGCACCGCGTTCGCGTACTCGGACGACCTGTCGCCCGAGGCGATCCG
CCAGGCGGCCGTCGCGACGAAGGCGATCGCGGCCGCGGGCGGCGGCAAGCAGAAGATCCGCGCGGCGACGGCGCTGAAGG
GCGTCTCGGGGCGCGACCTGTATCTGCCCGCCGATCCGCTCGCCTCGCTCGACGCGACCGCGAAGGTGAAGCTGCTCGAG
CGCGTCGAGCAGATGGCGCGCGGCCGCGACCCGCGCATCAAGCAGGTGATGGCGGGGCTCGCCGGCGAATACGACGTCGT
GCTCGTCGCGCGCAGCGACGGCGCGCTCGCGGCGGACATCCGCCCGCTCGTGCGCGTGTCGGTGACGGTGATCGCCGAGC
ACAACGGCCGGCGCGAGATCGGCACGGGCGGCGGCGGCGGCCGCTTCGACTACGGCTACTTCACCGACGACGTGCTCGCG
CGCTACGTCGACGACGCGGTGCACGCCGCGCTCGTCAACCTCGACGCGCGCCCGGCGCCCGCGGGCGCGATGACGGTCGT
GCTCGGCCCGGGCTGGCCCGGCGTGCTGCTGCACGAGGCGATCGGCCACGGGCTCGAGGGCGACTTCAACCGCAAGGGCT
CGTCGGCGTTCGCGGGCCGCATCGGCGAGCAGGTCGCGGCCAAGGGCGTGACCGTCGTCGACGACGGCACGCTGCCGAAC
CGCCGCGGATCGCTGAACATCGACGACGAGGGCAACCCGACGCAGTGCACGACGCTCATCGAGGACGGCATCCTGAAGGG
CTACATCCAGGACACGCTGAACGCGCGGCTGATGAAGATGCCCGTCACCGGCAACGCGCGGCGCGAATCGTACGCGGCGC
TGCCGATGCCGCGGATGACCAACACCTACATGCTCAACGGCGACAAGGACCCGCGGGAGATCATCGAATCGGTCAAGCAC
GGCCTGTACGCGGTGAACTTCGGCGGCGGCCAGGTCGACATCACGAACGGCAAGTTCGTGTTCTCGGCGTCCGAGGCATA
CATGATCGAGAACGGCAAGGTCACGTATCCGGTCAAGGGCGCGACGCTGATCGGCAGCGGCCCGGAATCGCTCAAGTACG
TGAGCATGATCGGCAACGACATGCGGCTCGACACGGGCGTCGGCGTGTGCGGCAAGGAAGGCCAGAGCGTGCCCGTCGGC
GTCGGCCAGCCGACGCTGCGGCTCGACAACATGACGGTGGGCGGCACCGCGTCGTAA

Upstream 100 bases:

>100_bases
CGGCATCGCGTGCTCGCGTGAGCGGCGATCCGCCCGACCGGAAAGAAGAAAGAAGGCGCGTCCGACAACCGTTTCAGAAT
TTGAGAATCCCCGAATCCGC

Downstream 100 bases:

>100_bases
TGCGGCGTTGCCGCATCGCGGCGCAGACAATTCGCGCGAATCGCCAATGTCGCGCGGATTGTCCGCATTTTCACGCGCAC
AGGATTGCAAGCCGGCCCCC

Product: TldD/PmbA family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MNIIEPGIPQGDFLQGARNLSLAKDILLTPYGLDEALLTRTLADIFTHRVDYADLYFQATRSEAWSLEEGIVKSGSFSID
QGVGVRAVAGERTAFAYSDDLSPEAIRQAAVATKAIAAAGGGKQKIRAATALKGVSGRDLYLPADPLASLDATAKVKLLE
RVEQMARGRDPRIKQVMAGLAGEYDVVLVARSDGALAADIRPLVRVSVTVIAEHNGRREIGTGGGGGRFDYGYFTDDVLA
RYVDDAVHAALVNLDARPAPAGAMTVVLGPGWPGVLLHEAIGHGLEGDFNRKGSSAFAGRIGEQVAAKGVTVVDDGTLPN
RRGSLNIDDEGNPTQCTTLIEDGILKGYIQDTLNARLMKMPVTGNARRESYAALPMPRMTNTYMLNGDKDPREIIESVKH
GLYAVNFGGGQVDITNGKFVFSASEAYMIENGKVTYPVKGATLIGSGPESLKYVSMIGNDMRLDTGVGVCGKEGQSVPVG
VGQPTLRLDNMTVGGTAS

Sequences:

>Translated_498_residues
MNIIEPGIPQGDFLQGARNLSLAKDILLTPYGLDEALLTRTLADIFTHRVDYADLYFQATRSEAWSLEEGIVKSGSFSID
QGVGVRAVAGERTAFAYSDDLSPEAIRQAAVATKAIAAAGGGKQKIRAATALKGVSGRDLYLPADPLASLDATAKVKLLE
RVEQMARGRDPRIKQVMAGLAGEYDVVLVARSDGALAADIRPLVRVSVTVIAEHNGRREIGTGGGGGRFDYGYFTDDVLA
RYVDDAVHAALVNLDARPAPAGAMTVVLGPGWPGVLLHEAIGHGLEGDFNRKGSSAFAGRIGEQVAAKGVTVVDDGTLPN
RRGSLNIDDEGNPTQCTTLIEDGILKGYIQDTLNARLMKMPVTGNARRESYAALPMPRMTNTYMLNGDKDPREIIESVKH
GLYAVNFGGGQVDITNGKFVFSASEAYMIENGKVTYPVKGATLIGSGPESLKYVSMIGNDMRLDTGVGVCGKEGQSVPVG
VGQPTLRLDNMTVGGTAS
>Mature_498_residues
MNIIEPGIPQGDFLQGARNLSLAKDILLTPYGLDEALLTRTLADIFTHRVDYADLYFQATRSEAWSLEEGIVKSGSFSID
QGVGVRAVAGERTAFAYSDDLSPEAIRQAAVATKAIAAAGGGKQKIRAATALKGVSGRDLYLPADPLASLDATAKVKLLE
RVEQMARGRDPRIKQVMAGLAGEYDVVLVARSDGALAADIRPLVRVSVTVIAEHNGRREIGTGGGGGRFDYGYFTDDVLA
RYVDDAVHAALVNLDARPAPAGAMTVVLGPGWPGVLLHEAIGHGLEGDFNRKGSSAFAGRIGEQVAAKGVTVVDDGTLPN
RRGSLNIDDEGNPTQCTTLIEDGILKGYIQDTLNARLMKMPVTGNARRESYAALPMPRMTNTYMLNGDKDPREIIESVKH
GLYAVNFGGGQVDITNGKFVFSASEAYMIENGKVTYPVKGATLIGSGPESLKYVSMIGNDMRLDTGVGVCGKEGQSVPVG
VGQPTLRLDNMTVGGTAS

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=485, Percent_Identity=59.3814432989691, Blast_Score=550, Evalue=1e-158,
Organism=Escherichia coli, GI1790682, Length=453, Percent_Identity=24.2825607064018, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 52685; Mature: 52685

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIIEPGIPQGDFLQGARNLSLAKDILLTPYGLDEALLTRTLADIFTHRVDYADLYFQAT
CCCCCCCCCCCHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHEEEEC
RSEAWSLEEGIVKSGSFSIDQGVGVRAVAGERTAFAYSDDLSPEAIRQAAVATKAIAAAG
CCHHHCHHHHHHCCCCCCCCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHCC
GGKQKIRAATALKGVSGRDLYLPADPLASLDATAKVKLLERVEQMARGRDPRIKQVMAGL
CCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHH
AGEYDVVLVARSDGALAADIRPLVRVSVTVIAEHNGRREIGTGGGGGRFDYGYFTDDVLA
CCCCEEEEEECCCCCEEHHCCCEEEEEEEEEEECCCCEECCCCCCCCCCCCCCCCHHHHH
RYVDDAVHAALVNLDARPAPAGAMTVVLGPGWPGVLLHEAIGHGLEGDFNRKGSSAFAGR
HHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHH
IGEQVAAKGVTVVDDGTLPNRRGSLNIDDEGNPTQCTTLIEDGILKGYIQDTLNARLMKM
HHHHHHHCCCEEEECCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEE
PVTGNARRESYAALPMPRMTNTYMLNGDKDPREIIESVKHGLYAVNFGGGQVDITNGKFV
CCCCCCCCCCEECCCCCCCCCEEEECCCCCHHHHHHHHHCCEEEEEECCCEEEEECCEEE
FSASEAYMIENGKVTYPVKGATLIGSGPESLKYVSMIGNDMRLDTGVGVCGKEGQSVPVG
EECCCEEEEECCEEEEEECCCEEECCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCC
VGQPTLRLDNMTVGGTAS
CCCCCEEECCEECCCCCC
>Mature Secondary Structure
MNIIEPGIPQGDFLQGARNLSLAKDILLTPYGLDEALLTRTLADIFTHRVDYADLYFQAT
CCCCCCCCCCCHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHEEEEC
RSEAWSLEEGIVKSGSFSIDQGVGVRAVAGERTAFAYSDDLSPEAIRQAAVATKAIAAAG
CCHHHCHHHHHHCCCCCCCCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHCC
GGKQKIRAATALKGVSGRDLYLPADPLASLDATAKVKLLERVEQMARGRDPRIKQVMAGL
CCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHH
AGEYDVVLVARSDGALAADIRPLVRVSVTVIAEHNGRREIGTGGGGGRFDYGYFTDDVLA
CCCCEEEEEECCCCCEEHHCCCEEEEEEEEEEECCCCEECCCCCCCCCCCCCCCCHHHHH
RYVDDAVHAALVNLDARPAPAGAMTVVLGPGWPGVLLHEAIGHGLEGDFNRKGSSAFAGR
HHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHH
IGEQVAAKGVTVVDDGTLPNRRGSLNIDDEGNPTQCTTLIEDGILKGYIQDTLNARLMKM
HHHHHHHCCCEEEECCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEE
PVTGNARRESYAALPMPRMTNTYMLNGDKDPREIIESVKHGLYAVNFGGGQVDITNGKFV
CCCCCCCCCCEECCCCCCCCCEEEECCCCCHHHHHHHHHCCEEEEEECCCEEEEECCEEE
FSASEAYMIENGKVTYPVKGATLIGSGPESLKYVSMIGNDMRLDTGVGVCGKEGQSVPVG
EECCCEEEEECCEEEEEECCCEEECCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCC
VGQPTLRLDNMTVGGTAS
CCCCCEEECCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]