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The map label for this gene is hetI [H]

Identifier: 126453859

GI number: 126453859

Start: 2694144

End: 2694947

Strand: Reverse

Name: hetI [H]

Synonym: BURPS1106A_2727

Alternate gene names: 126453859

Gene position: 2694947-2694144 (Counterclockwise)

Preceding gene: 126452498

Following gene: 126454745

Centisome position: 67.57

GC content: 76.0

Gene sequence:

>804_bases
GTGTTGCCGCCGATGCGCCTGCCGACCGAAGCCGCCTTGCCGCTCCCGACCGATGACGCGTATCGCGCCGTCGAACTATC
GCCGCCGCCCGCGGCGCAACGCGCCGGCGTGCGGCTCGTGCGGCTCGATTTCGATTTCGACGCCGCGCACCGCACGCGCG
CGCTGGCATCGCTGAGCGACGCCGAGCGCGAGCGCGCGCGGCGCTTCGTGCGCGTGGAAGACAGGCTGCGCAGCGCCGCG
ACGCGCGCGGTCGTGCGCGGCGTGATCGGCGCGACGCTCGGCTTGCCGCCCGCCGAGCTGCGGCTCGGCGCCGACGCGTC
GGGGCGCCCGCGGCTCGCGCCCGAACAGGCGGCGCTCGCGCCGACGCTCGACTTCAACGTGTCGCATTCGGGCGCGCATG
CGCTGATCGCATGGAGCCGCGCGGCGCGCGTCGGCGTCGACATCGAGGCGCGGCGCGCGGGCGTCGACTGGAGCTCGCTC
GGCCGCGCGGTGTTCGCGCCCGCGGATGCGGCGGCGATCGACGCGCTGCCGGTGGACGAACGCGAATCGGCGTGCTATCG
CGTGTGGGCGGCGAAGGAGGCGCTGCTGAAAGCGCTCGGCACCGGGATCGGCGGCGGCTTGACCGCGTTTTCGGTGCTCG
CGGGCGGCGCGCCGTCGGGCGAGGGTTTCGCGCCCACGATCGGCATCGACGAGCCGACGTCGCCCGCGAGCGGCGTGGCG
GCGTTCGACGCCGCATGGCTCGACGCGCCCACGGGCTATGCGGCCTGCGTGGCGTGGCGACGTGTGGAGCAGGGGGGAGC
CTAG

Upstream 100 bases:

>100_bases
CCCGCTGAGCGGCGCGAGACGCGCGGCGGCCGCCGCCGGCTGCGTTCGGCGCGCGCGAAGATCCGTTACCATCGAACGCT
TTCCACCGCCTGCACGACGT

Downstream 100 bases:

>100_bases
CAGGCTGTTGAAATTGGATACGGTGTAAACGGGCGTTGCGAGCGGTGCGTTAGAGATATCGTGTTCATGATCTTGGGCAG
ACGAGAGCGATGCGCGGAAT

Product: 4'-phosphopantetheinyl transferase superfamily protein

Products: adenosine 3',5'-bisphosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MLPPMRLPTEAALPLPTDDAYRAVELSPPPAAQRAGVRLVRLDFDFDAAHRTRALASLSDAERERARRFVRVEDRLRSAA
TRAVVRGVIGATLGLPPAELRLGADASGRPRLAPEQAALAPTLDFNVSHSGAHALIAWSRAARVGVDIEARRAGVDWSSL
GRAVFAPADAAAIDALPVDERESACYRVWAAKEALLKALGTGIGGGLTAFSVLAGGAPSGEGFAPTIGIDEPTSPASGVA
AFDAAWLDAPTGYAACVAWRRVEQGGA

Sequences:

>Translated_267_residues
MLPPMRLPTEAALPLPTDDAYRAVELSPPPAAQRAGVRLVRLDFDFDAAHRTRALASLSDAERERARRFVRVEDRLRSAA
TRAVVRGVIGATLGLPPAELRLGADASGRPRLAPEQAALAPTLDFNVSHSGAHALIAWSRAARVGVDIEARRAGVDWSSL
GRAVFAPADAAAIDALPVDERESACYRVWAAKEALLKALGTGIGGGLTAFSVLAGGAPSGEGFAPTIGIDEPTSPASGVA
AFDAAWLDAPTGYAACVAWRRVEQGGA
>Mature_267_residues
MLPPMRLPTEAALPLPTDDAYRAVELSPPPAAQRAGVRLVRLDFDFDAAHRTRALASLSDAERERARRFVRVEDRLRSAA
TRAVVRGVIGATLGLPPAELRLGADASGRPRLAPEQAALAPTLDFNVSHSGAHALIAWSRAARVGVDIEARRAGVDWSSL
GRAVFAPADAAAIDALPVDERESACYRVWAAKEALLKALGTGIGGGLTAFSVLAGGAPSGEGFAPTIGIDEPTSPASGVA
AFDAAWLDAPTGYAACVAWRRVEQGGA

Specific function: Probably activates the acyl carrier protein (ACP) domain of hetM, by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (CoA) to a serine residue. May be required for maintaining vegetative growth and probably acts via hetN to inhibit differenti

COG id: COG2091

COG function: function code H; Phosphopantetheinyl transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. Gsp/sfp/hetI/acpT family [H]

Homologues:

Organism=Homo sapiens, GI20357568, Length=161, Percent_Identity=30.4347826086957, Blast_Score=79, Evalue=5e-15,
Organism=Escherichia coli, GI1789886, Length=115, Percent_Identity=35.6521739130435, Blast_Score=63, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24663173, Length=191, Percent_Identity=29.8429319371728, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008278 [H]

Pfam domain/function: PF01648 ACPS [H]

EC number: NA

Molecular weight: Translated: 27788; Mature: 27788

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPPMRLPTEAALPLPTDDAYRAVELSPPPAAQRAGVRLVRLDFDFDAAHRTRALASLSD
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHCCEEEEEEECCCCHHHHHHHHHHHHH
AERERARRFVRVEDRLRSAATRAVVRGVIGATLGLPPAELRLGADASGRPRLAPEQAALA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEECCCCCCCCCCCCCHHHCC
PTLDFNVSHSGAHALIAWSRAARVGVDIEARRAGVDWSSLGRAVFAPADAAAIDALPVDE
CEEECCCCCCCCEEEEEEHHHHHCCCCCHHHHCCCCHHHHCCEEECCCCCHHHCCCCCCC
RESACYRVWAAKEALLKALGTGIGGGLTAFSVLAGGAPSGEGFAPTIGIDEPTSPASGVA
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCH
AFDAAWLDAPTGYAACVAWRRVEQGGA
HHHHHHHCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLPPMRLPTEAALPLPTDDAYRAVELSPPPAAQRAGVRLVRLDFDFDAAHRTRALASLSD
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHCCEEEEEEECCCCHHHHHHHHHHHHH
AERERARRFVRVEDRLRSAATRAVVRGVIGATLGLPPAELRLGADASGRPRLAPEQAALA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEECCCCCCCCCCCCCHHHCC
PTLDFNVSHSGAHALIAWSRAARVGVDIEARRAGVDWSSLGRAVFAPADAAAIDALPVDE
CEEECCCCCCCCEEEEEEHHHHHCCCCCHHHHCCCCHHHHCCEEECCCCCHHHCCCCCCC
RESACYRVWAAKEALLKALGTGIGGGLTAFSVLAGGAPSGEGFAPTIGIDEPTSPASGVA
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCH
AFDAAWLDAPTGYAACVAWRRVEQGGA
HHHHHHHCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coenzyme A; apo-[acyl carrier protein] [C]

Specific reaction: Coenzyme A + apo-[acyl carrier protein] = adenosine 3',5'-bisphosphate + [acyl carrier protein] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8157596; 11759840; 8939709 [H]