Click here to switch to the map view.

The map label for this gene is pcaR [H]

Identifier: 126453772

GI number: 126453772

Start: 3138919

End: 3139722

Strand: Reverse

Name: pcaR [H]

Synonym: BURPS1106A_3221

Alternate gene names: 126453772

Gene position: 3139722-3138919 (Counterclockwise)

Preceding gene: 126452406

Following gene: 126454489

Centisome position: 78.72

GC content: 71.14

Gene sequence:

>804_bases
GTGTATCACCGCATGAATTTTTCGACCATCGATGCCGACACGCTCGACGAACGCAAGTTCGTCGTCGCCCTCGCCCGGGG
GCTGGATCTGCTGCGCGCGTTCCGGCCCGGCGAGACGATGCTCGGCAACCGCGATTTCGCCGAGCGCACCGGGCTGCCGA
AGGCGACCGTCAACCGGCTCGCATACACGCTGACGGTGCTCGGCTATCTGCGCTACGACGACGCGCTCGGCAAGTACGCG
CTCGACGCGGGCGTGCTGTCGCTCGGCTACGCGTTGCTCGCGGGCTCGGACACGCTCGCGCTCGCGCGGCCGCACATGCA
GGCGCTCGCGCGCGAGATCGGCGCGGCGGTGTCGCTCGGCTGCCGTGACGGTCTCGACATGATCTACCTGGAGACGATTC
GCAGCGAGACGGCGCTGACGCTCGGGCTGGCGTCCGGCTCGCGGCTGTCGATGCTGACGAGCTCGATGGGGCGCGCGTAT
CTCGCCGTGCAGCCTCCCGACGCGCGCGCGGCGCTCTTCGCCGAGCTGCGCAAGACGGTGGGGAAGGGGCGGGCGGGGGC
GGCGCTCGTCGACGCGGCGCGGCGCGCGGCCGATGCGTTCGCGGCCGACGGCTGCTGCTATTCGTTTGGCGACTGGCACG
GCGACGTGAACGCGGCCGCCGTGCCGTTTCGCGAGCCGCGCGAAGGGCGCTGGCTGATTCTCAGTTGCAGCGGGCCGGCG
TCGTCGATGGGCGAGGACGTGTTCCGCAACCGGATTGGCCCGAAGCTGAAGGTGCTCGCGCGGCGGCTCGGAGAACCGGG
CTGA

Upstream 100 bases:

>100_bases
CAGCGGATCGTCCCAGTGGAAGGTTGCGGCAGCCATCTCGTCATCTCCTCGCTTGACTATAGTTCCGCTGTGCGGAACAA
TGTTTTGCAAATTGAGCCCA

Downstream 100 bases:

>100_bases
GCCCGCGAGCGGCGGCGGTCGAAGCGTCGAAGCGTCGAAGCGTCGAAGCGTCGAAGCGTCGAAGCGTCGAAGCGTCGAAG
CGTCGAAGCGTCGAAGCGTC

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MYHRMNFSTIDADTLDERKFVVALARGLDLLRAFRPGETMLGNRDFAERTGLPKATVNRLAYTLTVLGYLRYDDALGKYA
LDAGVLSLGYALLAGSDTLALARPHMQALAREIGAAVSLGCRDGLDMIYLETIRSETALTLGLASGSRLSMLTSSMGRAY
LAVQPPDARAALFAELRKTVGKGRAGAALVDAARRAADAFAADGCCYSFGDWHGDVNAAAVPFREPREGRWLILSCSGPA
SSMGEDVFRNRIGPKLKVLARRLGEPG

Sequences:

>Translated_267_residues
MYHRMNFSTIDADTLDERKFVVALARGLDLLRAFRPGETMLGNRDFAERTGLPKATVNRLAYTLTVLGYLRYDDALGKYA
LDAGVLSLGYALLAGSDTLALARPHMQALAREIGAAVSLGCRDGLDMIYLETIRSETALTLGLASGSRLSMLTSSMGRAY
LAVQPPDARAALFAELRKTVGKGRAGAALVDAARRAADAFAADGCCYSFGDWHGDVNAAAVPFREPREGRWLILSCSGPA
SSMGEDVFRNRIGPKLKVLARRLGEPG
>Mature_267_residues
MYHRMNFSTIDADTLDERKFVVALARGLDLLRAFRPGETMLGNRDFAERTGLPKATVNRLAYTLTVLGYLRYDDALGKYA
LDAGVLSLGYALLAGSDTLALARPHMQALAREIGAAVSLGCRDGLDMIYLETIRSETALTLGLASGSRLSMLTSSMGRAY
LAVQPPDARAALFAELRKTVGKGRAGAALVDAARRAADAFAADGCCYSFGDWHGDVNAAAVPFREPREGRWLILSCSGPA
SSMGEDVFRNRIGPKLKVLARRLGEPG

Specific function: Positive regulator of all genes within the pca regulon, pcaBDC, pcaIJ and pcaF. Also required for the chemotactic response to aromatic compounds [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI87082359, Length=231, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012794
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 28691; Mature: 28691

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED ; PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYHRMNFSTIDADTLDERKFVVALARGLDLLRAFRPGETMLGNRDFAERTGLPKATVNRL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCCCCHHHHCCCCHHHHHHH
AYTLTVLGYLRYDDALGKYALDAGVLSLGYALLAGSDTLALARPHMQALAREIGAAVSLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC
CRDGLDMIYLETIRSETALTLGLASGSRLSMLTSSMGRAYLAVQPPDARAALFAELRKTV
CCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHH
GKGRAGAALVDAARRAADAFAADGCCYSFGDWHGDVNAAAVPFREPREGRWLILSCSGPA
CCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCEECCCCCCCCCCEEEEECCCCC
SSMGEDVFRNRIGPKLKVLARRLGEPG
HHHHHHHHHHHCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MYHRMNFSTIDADTLDERKFVVALARGLDLLRAFRPGETMLGNRDFAERTGLPKATVNRL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCCCCHHHHCCCCHHHHHHH
AYTLTVLGYLRYDDALGKYALDAGVLSLGYALLAGSDTLALARPHMQALAREIGAAVSLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC
CRDGLDMIYLETIRSETALTLGLASGSRLSMLTSSMGRAYLAVQPPDARAALFAELRKTV
CCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHH
GKGRAGAALVDAARRAADAFAADGCCYSFGDWHGDVNAAAVPFREPREGRWLILSCSGPA
CCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCEECCCCCCCCCCEEEEECCCCC
SSMGEDVFRNRIGPKLKVLARRLGEPG
HHHHHHHHHHHCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083169 [H]