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The map label for this gene is lsfA [C]

Identifier: 126452406

GI number: 126452406

Start: 3141227

End: 3141865

Strand: Reverse

Name: lsfA [C]

Synonym: BURPS1106A_3223

Alternate gene names: 126452406

Gene position: 3141865-3141227 (Counterclockwise)

Preceding gene: 126452448

Following gene: 126453772

Centisome position: 78.77

GC content: 61.35

Gene sequence:

>639_bases
ATGAGTCTACGTCTTGGCGACATCGCGCCGGATTTCGAGCAGGATTCGAGCCTCGGCCGCATCAAATTTCACGAATGGCT
CGGCAATAGTTGGGGCGTCCTGTTCTCGCATCCGGCCGACTACACGCCCGTCTGCACGACGGAGCTCGGCTTGACCGCGA
AGCTCAAGGGAGAATTCGAGAAGCGCAACGTGAAGGTGATCGCGCTGTCGGTCGACAGCGTCGAGTCGCACAAGGGCTGG
ATCGACGACATCAACGAGACCCAGGCGACGAGCGTCGGCTTTCCGATCATCGCCGACGGCGATCGCAAGGTCTCGGAACT
CTACGACATGATCCATCCGAACGCGAACGAGACGCTGACCGTGCGTTCGCTGTTCGTGATCGATCCGAACAAGAAGGTGC
GCCTCATCATCACCTACCCGGCGAGCACCGGCCGCAACTTCGACGAAGTGCTGCGCGTCATCGATTCGCTGCAACTGACC
GATCACTACAAGGTCGCGACGCCCGGCAACTGGAAGGACGGCGACGACGTCGTGATCGTGCCGTCGCTGCAGGATCCGGA
CGAGCTGAAGCAGCGCTTCCCGAAGGGCTTCAAGGCCGTGCGTCCGTACCTGCGCCTGACGCCGCAGCCGAACAAATGA

Upstream 100 bases:

>100_bases
TAATCGTTCGCGCCGGCCGCAGGATCGCTTAAGCTAAAAACTTGTCCGGATGCGCGATGCGTCCGGGCACCCAACCCATG
CAAGTTCAAGGAGCTGTAAC

Downstream 100 bases:

>100_bases
GCGGCCTGCGCGCCGCGCGTCGGCGCGGCGTGGCGGTCATGAACGCAAAAAGCCCCGGCGGCGCGCCGGGGCTTTTTTTG
CGTTCGAGGCGGGCACATCG

Product: antioxidant protein LsfA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MSLRLGDIAPDFEQDSSLGRIKFHEWLGNSWGVLFSHPADYTPVCTTELGLTAKLKGEFEKRNVKVIALSVDSVESHKGW
IDDINETQATSVGFPIIADGDRKVSELYDMIHPNANETLTVRSLFVIDPNKKVRLIITYPASTGRNFDEVLRVIDSLQLT
DHYKVATPGNWKDGDDVVIVPSLQDPDELKQRFPKGFKAVRPYLRLTPQPNK

Sequences:

>Translated_212_residues
MSLRLGDIAPDFEQDSSLGRIKFHEWLGNSWGVLFSHPADYTPVCTTELGLTAKLKGEFEKRNVKVIALSVDSVESHKGW
IDDINETQATSVGFPIIADGDRKVSELYDMIHPNANETLTVRSLFVIDPNKKVRLIITYPASTGRNFDEVLRVIDSLQLT
DHYKVATPGNWKDGDDVVIVPSLQDPDELKQRFPKGFKAVRPYLRLTPQPNK
>Mature_211_residues
SLRLGDIAPDFEQDSSLGRIKFHEWLGNSWGVLFSHPADYTPVCTTELGLTAKLKGEFEKRNVKVIALSVDSVESHKGWI
DDINETQATSVGFPIIADGDRKVSELYDMIHPNANETLTVRSLFVIDPNKKVRLIITYPASTGRNFDEVLRVIDSLQLTD
HYKVATPGNWKDGDDVVIVPSLQDPDELKQRFPKGFKAVRPYLRLTPQPNK

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=222, Percent_Identity=52.7027027027027, Blast_Score=230, Evalue=6e-61,
Organism=Homo sapiens, GI32189392, Length=190, Percent_Identity=33.1578947368421, Blast_Score=100, Evalue=8e-22,
Organism=Homo sapiens, GI4505591, Length=191, Percent_Identity=30.8900523560209, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI32455266, Length=191, Percent_Identity=30.8900523560209, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI32455264, Length=191, Percent_Identity=30.8900523560209, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI5453549, Length=166, Percent_Identity=30.7228915662651, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI32483377, Length=164, Percent_Identity=31.0975609756098, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI5802974, Length=164, Percent_Identity=31.0975609756098, Blast_Score=80, Evalue=1e-15,
Organism=Escherichia coli, GI1786822, Length=154, Percent_Identity=33.7662337662338, Blast_Score=79, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI25153706, Length=226, Percent_Identity=41.1504424778761, Blast_Score=166, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI193204376, Length=189, Percent_Identity=30.1587301587302, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI32565831, Length=193, Percent_Identity=29.5336787564767, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17554494, Length=166, Percent_Identity=29.5180722891566, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319407, Length=212, Percent_Identity=56.1320754716981, Blast_Score=235, Evalue=3e-63,
Organism=Saccharomyces cerevisiae, GI6323613, Length=193, Percent_Identity=28.4974093264249, Blast_Score=76, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6320661, Length=185, Percent_Identity=29.1891891891892, Blast_Score=72, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24581278, Length=219, Percent_Identity=49.7716894977169, Blast_Score=217, Evalue=5e-57,
Organism=Drosophila melanogaster, GI24652436, Length=206, Percent_Identity=52.9126213592233, Blast_Score=203, Evalue=7e-53,
Organism=Drosophila melanogaster, GI24652434, Length=206, Percent_Identity=51.9417475728155, Blast_Score=201, Evalue=4e-52,
Organism=Drosophila melanogaster, GI17975518, Length=206, Percent_Identity=51.9417475728155, Blast_Score=200, Evalue=5e-52,
Organism=Drosophila melanogaster, GI17738015, Length=200, Percent_Identity=32, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI17157991, Length=174, Percent_Identity=32.7586206896552, Blast_Score=95, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24641739, Length=174, Percent_Identity=32.7586206896552, Blast_Score=95, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24656348, Length=192, Percent_Identity=31.7708333333333, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17864676, Length=192, Percent_Identity=31.7708333333333, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21357347, Length=176, Percent_Identity=28.9772727272727, Blast_Score=84, Evalue=9e-17,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 23862; Mature: 23731

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRLGDIAPDFEQDSSLGRIKFHEWLGNSWGVLFSHPADYTPVCTTELGLTAKLKGEFE
CCCCCCCCCCCCCCCCCCCEEEEHHHCCCCCCEEEECCCCCCCEEEECCCEEEEECCCCC
KRNVKVIALSVDSVESHKGWIDDINETQATSVGFPIIADGDRKVSELYDMIHPNANETLT
CCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHCCCCCCEEE
VRSLFVIDPNKKVRLIITYPASTGRNFDEVLRVIDSLQLTDHYKVATPGNWKDGDDVVIV
EEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCCEEEE
PSLQDPDELKQRFPKGFKAVRPYLRLTPQPNK
CCCCCHHHHHHHCCCCHHHHCHHEECCCCCCC
>Mature Secondary Structure 
SLRLGDIAPDFEQDSSLGRIKFHEWLGNSWGVLFSHPADYTPVCTTELGLTAKLKGEFE
CCCCCCCCCCCCCCCCCCEEEEHHHCCCCCCEEEECCCCCCCEEEECCCEEEEECCCCC
KRNVKVIALSVDSVESHKGWIDDINETQATSVGFPIIADGDRKVSELYDMIHPNANETLT
CCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHCCCCCCEEE
VRSLFVIDPNKKVRLIITYPASTGRNFDEVLRVIDSLQLTDHYKVATPGNWKDGDDVVIV
EEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCCEEEE
PSLQDPDELKQRFPKGFKAVRPYLRLTPQPNK
CCCCCHHHHHHHCCCCHHHHCHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]