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The map label for this gene is nudL [H]

Identifier: 126453578

GI number: 126453578

Start: 2859009

End: 2860292

Strand: Reverse

Name: nudL [H]

Synonym: BURPS1106A_2913

Alternate gene names: 126453578

Gene position: 2860292-2859009 (Counterclockwise)

Preceding gene: 126452689

Following gene: 126453201

Centisome position: 71.71

GC content: 69.47

Gene sequence:

>1284_bases
TTGCGACCGGACGTCGAATCGCGCGACCTCGCGTACCGGCTGCCTCGTTCGCGACAAGCCGGCAAAAGCGAGCCGGTATT
CGGAAGCGGAGCAGCGGATGCGAATCCGTCGGCTGCCATCGTTCCAACGCGTCCTTTCAACAAGCGAAGGGCGATTCAAA
CGGCCCGGCGCCCCATCGATGCGCCGGGCGCCGTGCAGGCGCGGCCACGCCGGCCGACGGCTGCTTGCCGAGAATTTCGC
GTGCGGGCCGATCTTGGGGCGTGTTCATGCCGCCGCACCCGAATCCGCGAGCGCGGCGTGGACCTCGATACGCGCCCGTC
GCCGCATCCGCCCATTCGCCCATTCGCATTGCGCACGGCGCATGGCGCATGGCGCACGGCCGACGACGCATGGCGCGGCC
GCTTGCCTGCGTTCGGCCGGCGAGCCGCGGCCGATAGCGTTTCCGCACCCTCGTCACGCAACGCGGCCCGACAGGCGCGC
CGTCCCATCGCGCGGCGCATGCCGCGCTCGACGGTGGCGCCATCCGGCGAGCGACTCGCCGCGCGCTTTTTTCTTTTCGG
CGCGACAATATGGCCATATCCATTCCGAGCAGAGCTTGACTTGATCCGTCGCCCCATCATCGACCCTGAAGTGCTGCCGA
TCGAGACGACCGGCGCCGACCTGCCAGTCGTCCGGCCGTCGTCGATGACGCCGGACGGCCTGCGCGAGCGTTTCGCCGAG
CCGCCCGAATGGACGCAGGAGCCCGCCGAGGCGCAGCTTGCCCACGGCGTCGATCCGCGCAGCGCGGCCGTGCTCGTGCC
GCTCGTCGTGCGTGAACGCGGCCTGACGGTGCTGCTCACGCAGCGCGCGGACCACCTGAACGATCATGCCGGCCAGATCA
GCTTTCCGGGCGGGCGCCGCGAGCCCGATGACCGCGACGCGAACGCCACCGCGCTGCGCGAGGCGCGCGAGGAAATCGCG
CTTGCGCACGAGCGCGTCGAGCTGCTGGGCGCGCTGCCCGACTATCTGACGGGCACGGGCTTTTGCGTGACGCCCGTCGT
CGGGCTCGTCCATCCGCCATTCACGGTGCAGCCGGATACGCTCGAAGTGGCCGAGATCTTCGAGGTGCCGCTCGATTTCC
TGATGAATCCCGCGCATCACCAGATCAGGGTGTTGCGCTGGGAGGGCGGCGAGCGGCGCTTTTTCGCGATGCCGTATCCG
CGCGGGCCGGTCGGCGGCCAGTATTTCATCTGGGGCGCGACGGCCGGCATGCTGCGCAACCTGTATCGCTTTCTGTCGGC
CTAA

Upstream 100 bases:

>100_bases
GCTGCGGCGGGGCGACACGCATGCGCCGCATCGCGGCGCGCGGGCAATGATGCCAGTCTATGCGAGTGCCGCCGCGCATA
CTGTCGAGCCATGTGTCTTT

Downstream 100 bases:

>100_bases
TGGCGCGCGCCACAGTCGGTGCACGCCGGAGCCATCCGCTGCGCCCGCTGTGCTATCTTTACGCGAAAAATCAATCATCC
AGAACGGCACGGCCCTTCGC

Product: MutT/NUDIX NTP pyrophosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MRPDVESRDLAYRLPRSRQAGKSEPVFGSGAADANPSAAIVPTRPFNKRRAIQTARRPIDAPGAVQARPRRPTAACREFR
VRADLGACSCRRTRIRERGVDLDTRPSPHPPIRPFALRTAHGAWRTADDAWRGRLPAFGRRAAADSVSAPSSRNAARQAR
RPIARRMPRSTVAPSGERLAARFFLFGATIWPYPFRAELDLIRRPIIDPEVLPIETTGADLPVVRPSSMTPDGLRERFAE
PPEWTQEPAEAQLAHGVDPRSAAVLVPLVVRERGLTVLLTQRADHLNDHAGQISFPGGRREPDDRDANATALREAREEIA
LAHERVELLGALPDYLTGTGFCVTPVVGLVHPPFTVQPDTLEVAEIFEVPLDFLMNPAHHQIRVLRWEGGERRFFAMPYP
RGPVGGQYFIWGATAGMLRNLYRFLSA

Sequences:

>Translated_427_residues
MRPDVESRDLAYRLPRSRQAGKSEPVFGSGAADANPSAAIVPTRPFNKRRAIQTARRPIDAPGAVQARPRRPTAACREFR
VRADLGACSCRRTRIRERGVDLDTRPSPHPPIRPFALRTAHGAWRTADDAWRGRLPAFGRRAAADSVSAPSSRNAARQAR
RPIARRMPRSTVAPSGERLAARFFLFGATIWPYPFRAELDLIRRPIIDPEVLPIETTGADLPVVRPSSMTPDGLRERFAE
PPEWTQEPAEAQLAHGVDPRSAAVLVPLVVRERGLTVLLTQRADHLNDHAGQISFPGGRREPDDRDANATALREAREEIA
LAHERVELLGALPDYLTGTGFCVTPVVGLVHPPFTVQPDTLEVAEIFEVPLDFLMNPAHHQIRVLRWEGGERRFFAMPYP
RGPVGGQYFIWGATAGMLRNLYRFLSA
>Mature_427_residues
MRPDVESRDLAYRLPRSRQAGKSEPVFGSGAADANPSAAIVPTRPFNKRRAIQTARRPIDAPGAVQARPRRPTAACREFR
VRADLGACSCRRTRIRERGVDLDTRPSPHPPIRPFALRTAHGAWRTADDAWRGRLPAFGRRAAADSVSAPSSRNAARQAR
RPIARRMPRSTVAPSGERLAARFFLFGATIWPYPFRAELDLIRRPIIDPEVLPIETTGADLPVVRPSSMTPDGLRERFAE
PPEWTQEPAEAQLAHGVDPRSAAVLVPLVVRERGLTVLLTQRADHLNDHAGQISFPGGRREPDDRDANATALREAREEIA
LAHERVELLGALPDYLTGTGFCVTPVVGLVHPPFTVQPDTLEVAEIFEVPLDFLMNPAHHQIRVLRWEGGERRFFAMPYP
RGPVGGQYFIWGATAGMLRNLYRFLSA

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=155, Percent_Identity=38.0645161290323, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1788115, Length=167, Percent_Identity=42.5149700598802, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17536993, Length=122, Percent_Identity=39.344262295082, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI18859683, Length=174, Percent_Identity=37.3563218390805, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 47415; Mature: 47415

Theoretical pI: Translated: 11.21; Mature: 11.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPDVESRDLAYRLPRSRQAGKSEPVFGSGAADANPSAAIVPTRPFNKRRAIQTARRPID
CCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCC
APGAVQARPRRPTAACREFRVRADLGACSCRRTRIRERGVDLDTRPSPHPPIRPFALRTA
CCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEC
HGAWRTADDAWRGRLPAFGRRAAADSVSAPSSRNAARQARRPIARRMPRSTVAPSGERLA
CCCCCCCCHHHHCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHH
ARFFLFGATIWPYPFRAELDLIRRPIIDPEVLPIETTGADLPVVRPSSMTPDGLRERFAE
HHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCEECCCCCCCHHHHHHCCC
PPEWTQEPAEAQLAHGVDPRSAAVLVPLVVRERGLTVLLTQRADHLNDHAGQISFPGGRR
CCCCCCCCHHHHHHCCCCCCCCEEEEHHHHHCCCCEEEEECCHHHHCCCCCEEECCCCCC
EPDDRDANATALREAREEIALAHERVELLGALPDYLTGTGFCVTPVVGLVHPPFTVQPDT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHCCCCCCCCCCC
LEVAEIFEVPLDFLMNPAHHQIRVLRWEGGERRFFAMPYPRGPVGGQYFIWGATAGMLRN
HHHHHHHHHHHHHHCCCCCCEEEEEEEECCCEEEEECCCCCCCCCCEEEEECCHHHHHHH
LYRFLSA
HHHHHCC
>Mature Secondary Structure
MRPDVESRDLAYRLPRSRQAGKSEPVFGSGAADANPSAAIVPTRPFNKRRAIQTARRPID
CCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCC
APGAVQARPRRPTAACREFRVRADLGACSCRRTRIRERGVDLDTRPSPHPPIRPFALRTA
CCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEC
HGAWRTADDAWRGRLPAFGRRAAADSVSAPSSRNAARQARRPIARRMPRSTVAPSGERLA
CCCCCCCCHHHHCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHH
ARFFLFGATIWPYPFRAELDLIRRPIIDPEVLPIETTGADLPVVRPSSMTPDGLRERFAE
HHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCEECCCCCCCHHHHHHCCC
PPEWTQEPAEAQLAHGVDPRSAAVLVPLVVRERGLTVLLTQRADHLNDHAGQISFPGGRR
CCCCCCCCHHHHHHCCCCCCCCEEEEHHHHHCCCCEEEEECCHHHHCCCCCEEECCCCCC
EPDDRDANATALREAREEIALAHERVELLGALPDYLTGTGFCVTPVVGLVHPPFTVQPDT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHCCCCCCCCCCC
LEVAEIFEVPLDFLMNPAHHQIRVLRWEGGERRFFAMPYPRGPVGGQYFIWGATAGMLRN
HHHHHHHHHHHHHHCCCCCCEEEEEEEECCCEEEEECCCCCCCCCCEEEEECCHHHHHHH
LYRFLSA
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]