| Definition | Burkholderia pseudomallei 1106a chromosome I, complete genome. |
|---|---|
| Accession | NC_009076 |
| Length | 3,988,455 |
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The map label for this gene is ydfG [H]
Identifier: 126453550
GI number: 126453550
Start: 3148803
End: 3149549
Strand: Direct
Name: ydfG [H]
Synonym: BURPS1106A_3236
Alternate gene names: 126453550
Gene position: 3148803-3149549 (Clockwise)
Preceding gene: 126453953
Following gene: 126453571
Centisome position: 78.95
GC content: 70.95
Gene sequence:
>747_bases ATGATCGTGTTCGTCACCGGTGCGTCGGCAGGTTTCGGCGCCGCCATCGCCCGTGCTTTCGTCCAGGGCGGCCACCGCGT CGTCGCCGCCGCCCGCCGCAAGGAGCGCCTCGACGCGCTCGCCGCCGAGCTCGGCAGCGCGCTGTTGCCGATCGAGCTCG ACGTGCGCGACCGTGCAGCCGTCGAAGCCGTGGCTGCCGCGCTGCCCACGGAGTTCGCCGCCATCGACGTCCTCGTCAAC AACGCGGGCCTCGCGCTCGGCGTCGAGCCCGCGCACCGGGCGAGCCTCGACGAGTGGCAGACGATGATCGACACCAACTG CACGGGCCTCGTCACGGTCACGCGCGCGCTGCTGCCCGGCATGGTCGAGCGCGGCCGCGGCCACATCTTCAACCTCGGCT CGGTCGCGGGCAGCTACCCGTACCCGGGCGGCAACGTCTATGGCGCGACCAAGGCGTTCGTGCGCCAGTTCAGCCTGAAC CTGCGCGCCGACCTGATCGGCACGCCGCTGCGCGTCACCGACATCGAGCCGGGCCTCTGCGGCGGCACCGAATTCTCGAA CGTGCGCTACCGCGGCGATGACGAGAAGGCGGCGAACGTCTACGCGAACGTCCAGCCGCTCACCGCCGAAGACATCGCCG ACACGATCTACTGGATCGCCACCCGCCCCGCGCACGTGAACATCAACACGATCGAGATGATGCCCGTCGCGCAGGCGCCC GCCGGCCTCGCCGTCCATCGCGGCTAA
Upstream 100 bases:
>100_bases ACATGCCCGCCAGCGCGCGCCGCCGCGCCTTGCCGCACCGCCGCGATGCCAGTAGGCTAACGAGTTCTCCCCAGCAAGCA TCGTTTTAGGAGCAGCAGCA
Downstream 100 bases:
>100_bases GCGCGCCGCCGGGGCGCGCACGCGGCCCGGCGGCCGGCCGGCAAAGGCAACATTCCGTTACGAATCCGGGGAATCGGGGT CGCCCGATCCGGTAGAATGC
Product: short chain dehydrogenase/reductase family oxidoreductase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 248; Mature: 248
Protein sequence:
>248_residues MIVFVTGASAGFGAAIARAFVQGGHRVVAAARRKERLDALAAELGSALLPIELDVRDRAAVEAVAAALPTEFAAIDVLVN NAGLALGVEPAHRASLDEWQTMIDTNCTGLVTVTRALLPGMVERGRGHIFNLGSVAGSYPYPGGNVYGATKAFVRQFSLN LRADLIGTPLRVTDIEPGLCGGTEFSNVRYRGDDEKAANVYANVQPLTAEDIADTIYWIATRPAHVNINTIEMMPVAQAP AGLAVHRG
Sequences:
>Translated_248_residues MIVFVTGASAGFGAAIARAFVQGGHRVVAAARRKERLDALAAELGSALLPIELDVRDRAAVEAVAAALPTEFAAIDVLVN NAGLALGVEPAHRASLDEWQTMIDTNCTGLVTVTRALLPGMVERGRGHIFNLGSVAGSYPYPGGNVYGATKAFVRQFSLN LRADLIGTPLRVTDIEPGLCGGTEFSNVRYRGDDEKAANVYANVQPLTAEDIADTIYWIATRPAHVNINTIEMMPVAQAP AGLAVHRG >Mature_248_residues MIVFVTGASAGFGAAIARAFVQGGHRVVAAARRKERLDALAAELGSALLPIELDVRDRAAVEAVAAALPTEFAAIDVLVN NAGLALGVEPAHRASLDEWQTMIDTNCTGLVTVTRALLPGMVERGRGHIFNLGSVAGSYPYPGGNVYGATKAFVRQFSLN LRADLIGTPLRVTDIEPGLCGGTEFSNVRYRGDDEKAANVYANVQPLTAEDIADTIYWIATRPAHVNINTIEMMPVAQAP AGLAVHRG
Specific function: Catalyzes the NADP-dependent oxidation of L-allo- threonine and L-serine [H]
COG id: COG4221
COG function: function code R; Short-chain alcohol dehydrogenase of unknown specificity
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI109715829, Length=248, Percent_Identity=35.0806451612903, Blast_Score=133, Evalue=1e-31, Organism=Homo sapiens, GI7706318, Length=186, Percent_Identity=35.4838709677419, Blast_Score=96, Evalue=2e-20, Organism=Homo sapiens, GI20149619, Length=186, Percent_Identity=31.7204301075269, Blast_Score=91, Evalue=8e-19, Organism=Homo sapiens, GI157739938, Length=184, Percent_Identity=31.5217391304348, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI40548397, Length=179, Percent_Identity=33.5195530726257, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI214010158, Length=179, Percent_Identity=33.5195530726257, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI214010156, Length=179, Percent_Identity=33.5195530726257, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI22758144, Length=179, Percent_Identity=33.5195530726257, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI7657478, Length=186, Percent_Identity=37.6344086021505, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI150247226, Length=178, Percent_Identity=34.8314606741573, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI22507405, Length=178, Percent_Identity=33.7078651685393, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI7705855, Length=194, Percent_Identity=29.3814432989691, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI4557649, Length=178, Percent_Identity=30.8988764044944, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI19923817, Length=187, Percent_Identity=27.807486631016, Blast_Score=76, Evalue=2e-14, Organism=Homo sapiens, GI19743808, Length=183, Percent_Identity=31.1475409836066, Blast_Score=76, Evalue=4e-14, Organism=Homo sapiens, GI32483357, Length=210, Percent_Identity=28.0952380952381, Blast_Score=74, Evalue=9e-14, Organism=Homo sapiens, GI10190704, Length=228, Percent_Identity=27.6315789473684, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI50726952, Length=180, Percent_Identity=32.7777777777778, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI40254992, Length=178, Percent_Identity=29.2134831460674, Blast_Score=68, Evalue=6e-12, Organism=Homo sapiens, GI44680136, Length=184, Percent_Identity=29.3478260869565, Blast_Score=65, Evalue=5e-11, Organism=Homo sapiens, GI44680133, Length=184, Percent_Identity=29.3478260869565, Blast_Score=65, Evalue=5e-11, Organism=Homo sapiens, GI17738292, Length=184, Percent_Identity=29.3478260869565, Blast_Score=65, Evalue=5e-11, Organism=Homo sapiens, GI119392083, Length=204, Percent_Identity=28.4313725490196, Blast_Score=65, Evalue=6e-11, Organism=Escherichia coli, GI1787820, Length=247, Percent_Identity=66.8016194331984, Blast_Score=354, Evalue=3e-99, Organism=Escherichia coli, GI1787335, Length=237, Percent_Identity=30.379746835443, Blast_Score=95, Evalue=4e-21, Organism=Escherichia coli, GI87082100, Length=180, Percent_Identity=35, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI1786812, Length=242, Percent_Identity=28.099173553719, Blast_Score=68, Evalue=5e-13, Organism=Escherichia coli, GI1786701, Length=200, Percent_Identity=29, Blast_Score=65, Evalue=3e-12, Organism=Caenorhabditis elegans, GI71994604, Length=238, Percent_Identity=26.0504201680672, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI71994600, Length=239, Percent_Identity=25.1046025104602, Blast_Score=78, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17562908, Length=188, Percent_Identity=28.7234042553192, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17538480, Length=246, Percent_Identity=27.6422764227642, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI17559104, Length=241, Percent_Identity=25.7261410788382, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI17562910, Length=247, Percent_Identity=26.7206477732794, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI17560676, Length=202, Percent_Identity=26.7326732673267, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17544670, Length=245, Percent_Identity=25.7142857142857, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17560332, Length=245, Percent_Identity=27.3469387755102, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI193204405, Length=195, Percent_Identity=29.2307692307692, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17560150, Length=184, Percent_Identity=27.7173913043478, Blast_Score=67, Evalue=6e-12, Organism=Caenorhabditis elegans, GI17562990, Length=186, Percent_Identity=28.494623655914, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17562906, Length=188, Percent_Identity=27.1276595744681, Blast_Score=67, Evalue=9e-12, Organism=Caenorhabditis elegans, GI17562904, Length=240, Percent_Identity=28.75, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17560220, Length=191, Percent_Identity=28.7958115183246, Blast_Score=66, Evalue=1e-11, Organism=Caenorhabditis elegans, GI115534660, Length=180, Percent_Identity=25.5555555555556, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17563726, Length=238, Percent_Identity=26.4705882352941, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17565030, Length=253, Percent_Identity=28.4584980237154, Blast_Score=64, Evalue=1e-10, Organism=Saccharomyces cerevisiae, GI6323882, Length=245, Percent_Identity=40.8163265306122, Blast_Score=174, Evalue=1e-44, Organism=Saccharomyces cerevisiae, GI6322067, Length=176, Percent_Identity=28.9772727272727, Blast_Score=72, Evalue=6e-14, Organism=Saccharomyces cerevisiae, GI6322227, Length=199, Percent_Identity=25.1256281407035, Blast_Score=68, Evalue=1e-12, Organism=Drosophila melanogaster, GI116007236, Length=251, Percent_Identity=33.8645418326693, Blast_Score=121, Evalue=4e-28, Organism=Drosophila melanogaster, GI21358495, Length=184, Percent_Identity=33.1521739130435, Blast_Score=102, Evalue=3e-22, Organism=Drosophila melanogaster, GI281364494, Length=247, Percent_Identity=30.7692307692308, Blast_Score=101, Evalue=4e-22, Organism=Drosophila melanogaster, GI116007238, Length=186, Percent_Identity=36.0215053763441, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI161076933, Length=179, Percent_Identity=32.9608938547486, Blast_Score=91, Evalue=9e-19, Organism=Drosophila melanogaster, GI24584748, Length=179, Percent_Identity=32.9608938547486, Blast_Score=91, Evalue=1e-18, Organism=Drosophila melanogaster, GI23397609, Length=229, Percent_Identity=29.2576419213974, Blast_Score=90, Evalue=2e-18, Organism=Drosophila melanogaster, GI24663911, Length=248, Percent_Identity=29.8387096774194, Blast_Score=89, Evalue=3e-18, Organism=Drosophila melanogaster, GI28571526, Length=236, Percent_Identity=29.2372881355932, Blast_Score=89, Evalue=3e-18, Organism=Drosophila melanogaster, GI116007234, Length=251, Percent_Identity=32.2709163346614, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI24641232, Length=255, Percent_Identity=29.0196078431373, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI24643142, Length=176, Percent_Identity=32.3863636363636, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI24641388, Length=250, Percent_Identity=31.2, Blast_Score=85, Evalue=5e-17, Organism=Drosophila melanogaster, GI21357041, Length=236, Percent_Identity=27.1186440677966, Blast_Score=84, Evalue=7e-17, Organism=Drosophila melanogaster, GI28571387, Length=250, Percent_Identity=29.6, Blast_Score=81, Evalue=7e-16, Organism=Drosophila melanogaster, GI24640442, Length=192, Percent_Identity=28.125, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI24584744, Length=185, Percent_Identity=32.972972972973, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI28574402, Length=185, Percent_Identity=32.972972972973, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI24644339, Length=234, Percent_Identity=27.7777777777778, Blast_Score=78, Evalue=7e-15, Organism=Drosophila melanogaster, GI24648693, Length=249, Percent_Identity=29.3172690763052, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI21355889, Length=249, Percent_Identity=29.3172690763052, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24580925, Length=230, Percent_Identity=30, Blast_Score=75, Evalue=3e-14, Organism=Drosophila melanogaster, GI21355631, Length=169, Percent_Identity=28.4023668639053, Blast_Score=71, Evalue=5e-13, Organism=Drosophila melanogaster, GI24648944, Length=239, Percent_Identity=27.1966527196653, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI281364892, Length=198, Percent_Identity=31.3131313131313, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI24584752, Length=180, Percent_Identity=30, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI17737361, Length=191, Percent_Identity=31.9371727748691, Blast_Score=67, Evalue=8e-12, Organism=Drosophila melanogaster, GI116007232, Length=186, Percent_Identity=34.9462365591398, Blast_Score=67, Evalue=9e-12,
Paralogues:
None
Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.-.-.- [C]
Molecular weight: Translated: 26161; Mature: 26161
Theoretical pI: Translated: 6.02; Mature: 6.02
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MIVFVTGASAGFGAAIARAFVQGGHRVVAAARRKERLDALAAELGSALLPIELDVRDRAA CEEEEECCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHH VEAVAAALPTEFAAIDVLVNNAGLALGVEPAHRASLDEWQTMIDTNCTGLVTVTRALLPG HHHHHHHCCCHHEEEEEEEECCCEEEECCCHHHCCHHHHHHHHHCCCCHHHHHHHHHHHH MVERGRGHIFNLGSVAGSYPYPGGNVYGATKAFVRQFSLNLRADLIGTPLRVTDIEPGLC HHHCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEHHCCCCEEEEECCCCCC GGTEFSNVRYRGDDEKAANVYANVQPLTAEDIADTIYWIATRPAHVNINTIEMMPVAQAP CCCCCCCCEECCCCCHHHEEEECCCCCCHHHHHHHEEEEEECCCEEEEEEEEEEECCCCC AGLAVHRG CCEEEECC >Mature Secondary Structure MIVFVTGASAGFGAAIARAFVQGGHRVVAAARRKERLDALAAELGSALLPIELDVRDRAA CEEEEECCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHH VEAVAAALPTEFAAIDVLVNNAGLALGVEPAHRASLDEWQTMIDTNCTGLVTVTRALLPG HHHHHHHCCCHHEEEEEEEECCCEEEECCCHHHCCHHHHHHHHHCCCCHHHHHHHHHHHH MVERGRGHIFNLGSVAGSYPYPGGNVYGATKAFVRQFSLNLRADLIGTPLRVTDIEPGLC HHHCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEHHCCCCEEEEECCCCCC GGTEFSNVRYRGDDEKAANVYANVQPLTAEDIADTIYWIATRPAHVNINTIEMMPVAQAP CCCCCCCCEECCCCCHHHEEEECCCCCCHHHHHHHEEEEEECCCEEEEEEEEEEECCCCC AGLAVHRG CCEEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 11677608; 12644504 [H]