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The map label for this gene is nuoG [H]

Identifier: 126453390

GI number: 126453390

Start: 1275824

End: 1278154

Strand: Direct

Name: nuoG [H]

Synonym: BURPS1106A_1305

Alternate gene names: 126453390

Gene position: 1275824-1278154 (Clockwise)

Preceding gene: 126454273

Following gene: 126452023

Centisome position: 31.99

GC content: 68.64

Gene sequence:

>2331_bases
ATGGTTGAACTTGAAATAGACGGCAAGAAGGTCGAGGTGCCCGAAGGCAGCATGGTGATCCAGGCTGCGCACAAGGCGGA
CACGTACATCCCTCACTTCTGCTATCACAAGAAGCTCTCGGTTGCGGCCAACTGCCGGATGTGTCTCGTCGAAGTCGAGA
AGATGCCGAAGGCCGTGCCCGCATGCGCGACGCCCGTGTCGGCCGGCATGATCGTCCACACCAACTCCGAGAAGGCCGTG
AAGGCGCAGCAGTCGGTGATGGAGTTCCTGCTCATCAACCATCCGCTCGACTGCCCGATCTGCGATCAGGGCGGCGAATG
CCAGTTGCAGGATCTCGCGGTCGGCTACGGCAAGTCGACGTCTCGCTACGCGGAAGAAAAGCGCGTGGTGTTCCACAAGG
AAGTCGGCCCGCTCATCTCGATGGAAGAGATGTCGCGCTGCATCCACTGCACGCGCTGCGTGCGCTTCGGTCAGGAAATC
GCCGGCGTGATGGAGTTCGGCATGCTCGGCCGCGGCGAGCACTCGGAAATCACGACGTTCGTCGGCAAGACGGTCGACTC
CGAGCTGTCGGGCAACATGATCGATCTGTGCCCGGTCGGCGCGCTGACGAGCAAGCCGTTCCGCTACAGTGCCCGCACGT
GGGAGCTGTCGCGCCGCAAGTCGGTGAGCCCGCACGATTCCGTCGGCGCGAACCTCGTCGTGCAAGTGAAAAACAACCGC
GTGATGCGCGTGCTGCCGTTCGAGAACGAAGCCGTCAACGAGTGCTGGATCTCGGACAAGGACCGCTTCTCGTATGAAGG
CCTGAACAGCGAAGAGCGCCTGACGAAGCCGATGATCAAGCAGGGCGGCGAGTGGCGCGAAGTCGACTGGCAGACCGCGC
TCGAATACGTCGCGCGCGGGCTGAAGGGCATCGGCGACGAGCATGGCCCGGCCGCGATCGCCGCGCTCGGCAGCGCGCAC
AGCACGGTCGAGGAACTGTTCTTGCTCAAGCAGCTCGCCCACGAGCTGAAGACGCCGAACGTCGACTTCCGTCTGCGTCA
GACCGATTTTTCCGCCGCCGCGCAAGGCGCGCCGTGGCTTGGCATGCCGATCGCCGATCTGTCGGCCGTCGACGCCGCGT
TCGTCGTCGGCTCGTTCCTGCGCCGCGATCATCCGCTCTTCGCGGCGCGCCTGCGCCAGGCGGCGAAGAACGGCGCGAAG
CTGCACTTCCTGCACGCCACGGGCGATGACGCGCTGATCCCGACCGCGCAGCGCATCGTCGCCGCGCCGTCGGCGTGGCT
CGACACGCTCGCCGGCGTCGCGGCCGCCGTCGCGCAAGCGCGCGGCGTCGCGCTGCCCGAGGCGCTCGCGGGCGTCGAGG
CGTCGGACGCCGCACGCTCGGTCGCGCAATCGCTCGCGAACGGCGAGCGCCGCGCGGTGCTGCTCGGCAACAGCGTCGTC
CGGCATCCGCAATTCGCGCAGATCCACGCGATCGCGCAGTGGATCGCCGAGAACACGGGGGCGACGCTCGGCTTCCTGAC
GGAAGCGGCGAACACGGTCGGCGCGCACCTCGTCGGCGCGCTGCCGGGCGCGAACGGCCTGAACGCGCGCGATGCGTTCG
CGCAGCCGCGCAAGGGCTACGTGCTCCTGAACGTCGAGCCGGAATTCGACACCGCCGATCCCGCGCAGGCGCTCGCCGCG
CTGAAGCAGGCGGAGACGGTCGTCGTGCTGTCGCCGTTCAAGTACGGCCTCGACTACGCGGACGTGCTGCTGCCGATCTC
GCCGTTCACCGAGACGGCCGGCACGTACGTGAACGCGGAAGGCCGCGCGCAGTCGTTCAACGGCGTCGTGCGTCCGCTCG
GCGACACGCGGCCCGCATGGAAGGTGTTGCGCGTGCTCGGCAGCCTGCTCGGCCTGCCGAACTTCGAGTACGAGACGTCG
GAAGAAGTGCGGCTCGCCGCGCTCGGCGACGGCGAGATCACGTCGCGCCTGTCGAACAAGACGGCGGCGGTGCCCGCGCG
CGCGGCCGCGAGGGCCGCGAACGGCGCGCTCGAGCGCCTCGCCGACGTGCCGATCTATCACGCGGACGCGCTGTCGCGCC
GCGCGGGCGCGCTGCATCTGACAGCCGCGTCGAAGGCGGCGCACCAGGTGGGCCTGCCCGCCGCGCTGTTCGACAAGCTC
GGTCTGAAGAACGGCGACGCGGTGCGCGTGCGCCAGGGCGATCGCACGGTGCAGCTGCCGGCCGTGCGCGACGAGAACCT
TGCGGAAGCCGTCGTCCGCGTGTCGGCGGCCACGCCTGCCGGCGCAGCGCTCGGCAGCCTGTCCGGTGAACTGGTGGTGG
AGAAGGCGTAA

Upstream 100 bases:

>100_bases
CATGCGGCCGCCGCCTGACGGCGCAACCCGATTGCAGAATTCGAGCGCCCGGTCGAGCGGACGCGGGCGAGCGGTAATAG
GTTAAGGACCATTCACCATC

Downstream 100 bases:

>100_bases
ATGAGCTTGTTCGATACGATCAACTCGGGCGGAGCCCAGCTTCTCGGCGTCGCATGGCCGACGGTGTGGGCGCTCGTGCG
CATCCTCGTCGTCGCCGTCG

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 776; Mature: 776

Protein sequence:

>776_residues
MVELEIDGKKVEVPEGSMVIQAAHKADTYIPHFCYHKKLSVAANCRMCLVEVEKMPKAVPACATPVSAGMIVHTNSEKAV
KAQQSVMEFLLINHPLDCPICDQGGECQLQDLAVGYGKSTSRYAEEKRVVFHKEVGPLISMEEMSRCIHCTRCVRFGQEI
AGVMEFGMLGRGEHSEITTFVGKTVDSELSGNMIDLCPVGALTSKPFRYSARTWELSRRKSVSPHDSVGANLVVQVKNNR
VMRVLPFENEAVNECWISDKDRFSYEGLNSEERLTKPMIKQGGEWREVDWQTALEYVARGLKGIGDEHGPAAIAALGSAH
STVEELFLLKQLAHELKTPNVDFRLRQTDFSAAAQGAPWLGMPIADLSAVDAAFVVGSFLRRDHPLFAARLRQAAKNGAK
LHFLHATGDDALIPTAQRIVAAPSAWLDTLAGVAAAVAQARGVALPEALAGVEASDAARSVAQSLANGERRAVLLGNSVV
RHPQFAQIHAIAQWIAENTGATLGFLTEAANTVGAHLVGALPGANGLNARDAFAQPRKGYVLLNVEPEFDTADPAQALAA
LKQAETVVVLSPFKYGLDYADVLLPISPFTETAGTYVNAEGRAQSFNGVVRPLGDTRPAWKVLRVLGSLLGLPNFEYETS
EEVRLAALGDGEITSRLSNKTAAVPARAAARAANGALERLADVPIYHADALSRRAGALHLTAASKAAHQVGLPAALFDKL
GLKNGDAVRVRQGDRTVQLPAVRDENLAEAVVRVSAATPAGAALGSLSGELVVEKA

Sequences:

>Translated_776_residues
MVELEIDGKKVEVPEGSMVIQAAHKADTYIPHFCYHKKLSVAANCRMCLVEVEKMPKAVPACATPVSAGMIVHTNSEKAV
KAQQSVMEFLLINHPLDCPICDQGGECQLQDLAVGYGKSTSRYAEEKRVVFHKEVGPLISMEEMSRCIHCTRCVRFGQEI
AGVMEFGMLGRGEHSEITTFVGKTVDSELSGNMIDLCPVGALTSKPFRYSARTWELSRRKSVSPHDSVGANLVVQVKNNR
VMRVLPFENEAVNECWISDKDRFSYEGLNSEERLTKPMIKQGGEWREVDWQTALEYVARGLKGIGDEHGPAAIAALGSAH
STVEELFLLKQLAHELKTPNVDFRLRQTDFSAAAQGAPWLGMPIADLSAVDAAFVVGSFLRRDHPLFAARLRQAAKNGAK
LHFLHATGDDALIPTAQRIVAAPSAWLDTLAGVAAAVAQARGVALPEALAGVEASDAARSVAQSLANGERRAVLLGNSVV
RHPQFAQIHAIAQWIAENTGATLGFLTEAANTVGAHLVGALPGANGLNARDAFAQPRKGYVLLNVEPEFDTADPAQALAA
LKQAETVVVLSPFKYGLDYADVLLPISPFTETAGTYVNAEGRAQSFNGVVRPLGDTRPAWKVLRVLGSLLGLPNFEYETS
EEVRLAALGDGEITSRLSNKTAAVPARAAARAANGALERLADVPIYHADALSRRAGALHLTAASKAAHQVGLPAALFDKL
GLKNGDAVRVRQGDRTVQLPAVRDENLAEAVVRVSAATPAGAALGSLSGELVVEKA
>Mature_776_residues
MVELEIDGKKVEVPEGSMVIQAAHKADTYIPHFCYHKKLSVAANCRMCLVEVEKMPKAVPACATPVSAGMIVHTNSEKAV
KAQQSVMEFLLINHPLDCPICDQGGECQLQDLAVGYGKSTSRYAEEKRVVFHKEVGPLISMEEMSRCIHCTRCVRFGQEI
AGVMEFGMLGRGEHSEITTFVGKTVDSELSGNMIDLCPVGALTSKPFRYSARTWELSRRKSVSPHDSVGANLVVQVKNNR
VMRVLPFENEAVNECWISDKDRFSYEGLNSEERLTKPMIKQGGEWREVDWQTALEYVARGLKGIGDEHGPAAIAALGSAH
STVEELFLLKQLAHELKTPNVDFRLRQTDFSAAAQGAPWLGMPIADLSAVDAAFVVGSFLRRDHPLFAARLRQAAKNGAK
LHFLHATGDDALIPTAQRIVAAPSAWLDTLAGVAAAVAQARGVALPEALAGVEASDAARSVAQSLANGERRAVLLGNSVV
RHPQFAQIHAIAQWIAENTGATLGFLTEAANTVGAHLVGALPGANGLNARDAFAQPRKGYVLLNVEPEFDTADPAQALAA
LKQAETVVVLSPFKYGLDYADVLLPISPFTETAGTYVNAEGRAQSFNGVVRPLGDTRPAWKVLRVLGSLLGLPNFEYETS
EEVRLAALGDGEITSRLSNKTAAVPARAAARAANGALERLADVPIYHADALSRRAGALHLTAASKAAHQVGLPAALFDKL
GLKNGDAVRVRQGDRTVQLPAVRDENLAEAVVRVSAATPAGAALGSLSGELVVEKA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=661, Percent_Identity=37.9727685325265, Blast_Score=407, Evalue=1e-113,
Organism=Escherichia coli, GI145693161, Length=678, Percent_Identity=26.8436578171091, Blast_Score=215, Evalue=8e-57,
Organism=Escherichia coli, GI3868721, Length=500, Percent_Identity=23.6, Blast_Score=83, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17565758, Length=660, Percent_Identity=36.5151515151515, Blast_Score=361, Evalue=1e-99,
Organism=Caenorhabditis elegans, GI32566231, Length=620, Percent_Identity=36.9354838709677, Blast_Score=342, Evalue=3e-94,
Organism=Caenorhabditis elegans, GI193209088, Length=254, Percent_Identity=51.1811023622047, Blast_Score=267, Evalue=2e-71,
Organism=Drosophila melanogaster, GI24640559, Length=656, Percent_Identity=39.0243902439024, Blast_Score=383, Evalue=1e-106,
Organism=Drosophila melanogaster, GI24640557, Length=656, Percent_Identity=39.0243902439024, Blast_Score=383, Evalue=1e-106,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 83041; Mature: 83041

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVELEIDGKKVEVPEGSMVIQAAHKADTYIPHFCYHKKLSVAANCRMCLVEVEKMPKAVP
CEEEEECCCEEECCCCCEEEEEHHHCCCCCCHHHHHCCHHHHHCCHHHHHHHHHCCCCCC
ACATPVSAGMIVHTNSEKAVKAQQSVMEFLLINHPLDCPICDQGGECQLQDLAVGYGKST
CCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEHEEECCCCCH
SRYAEEKRVVFHKEVGPLISMEEMSRCIHCTRCVRFGQEIAGVMEFGMLGRGEHSEITTF
HHHHHHHHEEEEHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
VGKTVDSELSGNMIDLCPVGALTSKPFRYSARTWELSRRKSVSPHDSVGANLVVQVKNNR
HHHHHHHHHCCCEEEECCCCCCCCCCCEECCCEEECHHHCCCCCCCCCCCEEEEEEECCC
VMRVLPFENEAVNECWISDKDRFSYEGLNSEERLTKPMIKQGGEWREVDWQTALEYVARG
EEEEECCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCHHHHHHHHHHH
LKGIGDEHGPAAIAALGSAHSTVEELFLLKQLAHELKTPNVDFRLRQTDFSAAAQGAPWL
HHHCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHCCCCCC
GMPIADLSAVDAAFVVGSFLRRDHPLFAARLRQAAKNGAKLHFLHATGDDALIPTAQRIV
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHH
AAPSAWLDTLAGVAAAVAQARGVALPEALAGVEASDAARSVAQSLANGERRAVLLGNSVV
HCCHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCHHH
RHPQFAQIHAIAQWIAENTGATLGFLTEAANTVGAHLVGALPGANGLNARDAFAQPRKGY
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCE
VLLNVEPEFDTADPAQALAALKQAETVVVLSPFKYGLDYADVLLPISPFTETAGTYVNAE
EEEEECCCCCCCCHHHHHHHHHHCCEEEEECCHHHCCCHHHHEEECCCCHHCCCCEECCC
GRAQSFNGVVRPLGDTRPAWKVLRVLGSLLGLPNFEYETSEEVRLAALGDGEITSRLSNK
CCCCCCCCHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCHHHHHHCCC
TAAVPARAAARAANGALERLADVPIYHADALSRRAGALHLTAASKAAHQVGLPAALFDKL
CCCCCHHHHHHHHHHHHHHHHCCCCEEHHHHHHCCCEEEEEHHHHHHHHCCCCHHHHHHH
GLKNGDAVRVRQGDRTVQLPAVRDENLAEAVVRVSAATPAGAALGSLSGELVVEKA
CCCCCCEEEEECCCCEEECCCCCCCHHHHHHHHHHCCCCCCHHHHCCCCCEEEECC
>Mature Secondary Structure
MVELEIDGKKVEVPEGSMVIQAAHKADTYIPHFCYHKKLSVAANCRMCLVEVEKMPKAVP
CEEEEECCCEEECCCCCEEEEEHHHCCCCCCHHHHHCCHHHHHCCHHHHHHHHHCCCCCC
ACATPVSAGMIVHTNSEKAVKAQQSVMEFLLINHPLDCPICDQGGECQLQDLAVGYGKST
CCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEHEEECCCCCH
SRYAEEKRVVFHKEVGPLISMEEMSRCIHCTRCVRFGQEIAGVMEFGMLGRGEHSEITTF
HHHHHHHHEEEEHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
VGKTVDSELSGNMIDLCPVGALTSKPFRYSARTWELSRRKSVSPHDSVGANLVVQVKNNR
HHHHHHHHHCCCEEEECCCCCCCCCCCEECCCEEECHHHCCCCCCCCCCCEEEEEEECCC
VMRVLPFENEAVNECWISDKDRFSYEGLNSEERLTKPMIKQGGEWREVDWQTALEYVARG
EEEEECCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCHHHHHHHHHHH
LKGIGDEHGPAAIAALGSAHSTVEELFLLKQLAHELKTPNVDFRLRQTDFSAAAQGAPWL
HHHCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHCCCCCC
GMPIADLSAVDAAFVVGSFLRRDHPLFAARLRQAAKNGAKLHFLHATGDDALIPTAQRIV
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHH
AAPSAWLDTLAGVAAAVAQARGVALPEALAGVEASDAARSVAQSLANGERRAVLLGNSVV
HCCHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCHHH
RHPQFAQIHAIAQWIAENTGATLGFLTEAANTVGAHLVGALPGANGLNARDAFAQPRKGY
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCE
VLLNVEPEFDTADPAQALAALKQAETVVVLSPFKYGLDYADVLLPISPFTETAGTYVNAE
EEEEECCCCCCCCHHHHHHHHHHCCEEEEECCHHHCCCHHHHEEECCCCHHCCCCEECCC
GRAQSFNGVVRPLGDTRPAWKVLRVLGSLLGLPNFEYETSEEVRLAALGDGEITSRLSNK
CCCCCCCCHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCHHHHHHCCC
TAAVPARAAARAANGALERLADVPIYHADALSRRAGALHLTAASKAAHQVGLPAALFDKL
CCCCCHHHHHHHHHHHHHHHHCCCCEEHHHHHHCCCEEEEEHHHHHHHHCCCCHHHHHHH
GLKNGDAVRVRQGDRTVQLPAVRDENLAEAVVRVSAATPAGAALGSLSGELVVEKA
CCCCCCEEEEECCCCEEECCCCCCCHHHHHHHHHHCCCCCCHHHHCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]