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The map label for this gene is nuoH [H]

Identifier: 126452023

GI number: 126452023

Start: 1278155

End: 1279219

Strand: Direct

Name: nuoH [H]

Synonym: BURPS1106A_1306

Alternate gene names: 126452023

Gene position: 1278155-1279219 (Clockwise)

Preceding gene: 126453390

Following gene: 126452103

Centisome position: 32.05

GC content: 63.47

Gene sequence:

>1065_bases
ATGAGCTTGTTCGATACGATCAACTCGGGCGGAGCCCAGCTTCTCGGCGTCGCATGGCCGACGGTGTGGGCGCTCGTGCG
CATCCTCGTCGTCGCCGTCGTGATCCTGCTGTGCGTCGCGTACCTGATTCTGTGGGAGCGCAAGCTGATCGGCTGGATGC
ACGTGCGTCTCGGTCCGAACCGCGTCGGCCCCGCGGGCCTGCTGCAGCCGATCGCCGACGTGCTGAAGCTGCTGCTCAAG
GAAGTGATTCGTCCGACGGCCGCGAGCCGCTGGCTGTATCTGGTCGCGCCCGTGATGACGGTGGTGCCGGCGTTCGCGGT
GTGGGCGGTGATCCCGTTCCAGGCGGGCGCGGTGCTCGCGAACATCAACGCCGGCCTGCTGTACGCGATGGCGATTTCGT
CGATCGGCGTCTACGCGGTGATTCTCGCCGGCTGGGCGTCGAACTCGAAGTACGCGTTTCTCGGCGCGATGCGCGCGGCC
GCGCAGATGGTGTCGTATGAAATCTCGATGGGCTTCGCGCTCGTGCTCGTGCTGATGACGGCGGGCAGCCTGAACCTGTC
GGAGATCGTCGGCTCGCAGCAGCACGGCTTCTTCGCGGGCCACGGCGTCAATTTCCTGTCGTGGAACTGGCTGCCGCTGC
TGCCCGTGTTCGTCATCTACTTCATCTCGGGCATCGCCGAAACGAACCGCCACCCGTTCGACGTGGTGGAAGGGGAATCG
GAAATCGTCGCGGGTCACATGATCGACTACTCGGGGATGGCGTTCGCGCTGTTCTTCCTCGCCGAGTACATCAACATGAT
CGTGATCTCGGCGCTCGCGGCGACGCTGTTCCTCGGCGGCTGGGACGCGCCGTTCGAATTCCTGTCGTTCATTCCGGGCA
TCTTCTGGCTGGTGCTGAAAATCTTCGCGCTGCTGTCGGTGTTCATTTGGGCCCGTGCGACGTTCCCGCGTTACCGCTAC
GACCAGATCATGCGCCTCGGCTGGAAGGTGTTCCTGCCCGTGTGCGTGTTCTGGGTGATCGTGGTCGGTTTCTGGATGAT
GTCGCCGCTGAATATCTGGAAATAA

Upstream 100 bases:

>100_bases
CGAGAACCTTGCGGAAGCCGTCGTCCGCGTGTCGGCGGCCACGCCTGCCGGCGCAGCGCTCGGCAGCCTGTCCGGTGAAC
TGGTGGTGGAGAAGGCGTAA

Downstream 100 bases:

>100_bases
AGGGCGGACGAAATCATGACGGCAATCCAACAATTCTTTAAGACCTTCTTCCTGACCGAGTTGCTCAAGGGGCTCGCGCT
GACCGGACGCTATACGTTCA

Product: NADH dehydrogenase subunit H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MSLFDTINSGGAQLLGVAWPTVWALVRILVVAVVILLCVAYLILWERKLIGWMHVRLGPNRVGPAGLLQPIADVLKLLLK
EVIRPTAASRWLYLVAPVMTVVPAFAVWAVIPFQAGAVLANINAGLLYAMAISSIGVYAVILAGWASNSKYAFLGAMRAA
AQMVSYEISMGFALVLVLMTAGSLNLSEIVGSQQHGFFAGHGVNFLSWNWLPLLPVFVIYFISGIAETNRHPFDVVEGES
EIVAGHMIDYSGMAFALFFLAEYINMIVISALAATLFLGGWDAPFEFLSFIPGIFWLVLKIFALLSVFIWARATFPRYRY
DQIMRLGWKVFLPVCVFWVIVVGFWMMSPLNIWK

Sequences:

>Translated_354_residues
MSLFDTINSGGAQLLGVAWPTVWALVRILVVAVVILLCVAYLILWERKLIGWMHVRLGPNRVGPAGLLQPIADVLKLLLK
EVIRPTAASRWLYLVAPVMTVVPAFAVWAVIPFQAGAVLANINAGLLYAMAISSIGVYAVILAGWASNSKYAFLGAMRAA
AQMVSYEISMGFALVLVLMTAGSLNLSEIVGSQQHGFFAGHGVNFLSWNWLPLLPVFVIYFISGIAETNRHPFDVVEGES
EIVAGHMIDYSGMAFALFFLAEYINMIVISALAATLFLGGWDAPFEFLSFIPGIFWLVLKIFALLSVFIWARATFPRYRY
DQIMRLGWKVFLPVCVFWVIVVGFWMMSPLNIWK
>Mature_353_residues
SLFDTINSGGAQLLGVAWPTVWALVRILVVAVVILLCVAYLILWERKLIGWMHVRLGPNRVGPAGLLQPIADVLKLLLKE
VIRPTAASRWLYLVAPVMTVVPAFAVWAVIPFQAGAVLANINAGLLYAMAISSIGVYAVILAGWASNSKYAFLGAMRAAA
QMVSYEISMGFALVLVLMTAGSLNLSEIVGSQQHGFFAGHGVNFLSWNWLPLLPVFVIYFISGIAETNRHPFDVVEGESE
IVAGHMIDYSGMAFALFFLAEYINMIVISALAATLFLGGWDAPFEFLSFIPGIFWLVLKIFALLSVFIWARATFPRYRYD
QIMRLGWKVFLPVCVFWVIVVGFWMMSPLNIWK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=302, Percent_Identity=42.7152317880795, Blast_Score=252, Evalue=4e-67,
Organism=Escherichia coli, GI1788618, Length=319, Percent_Identity=40.4388714733542, Blast_Score=255, Evalue=3e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 39188; Mature: 39057

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFDTINSGGAQLLGVAWPTVWALVRILVVAVVILLCVAYLILWERKLIGWMHVRLGPN
CCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCC
RVGPAGLLQPIADVLKLLLKEVIRPTAASRWLYLVAPVMTVVPAFAVWAVIPFQAGAVLA
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
NINAGLLYAMAISSIGVYAVILAGWASNSKYAFLGAMRAAAQMVSYEISMGFALVLVLMT
ECCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGSLNLSEIVGSQQHGFFAGHGVNFLSWNWLPLLPVFVIYFISGIAETNRHPFDVVEGES
CCCCCHHHHHCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEECCCC
EIVAGHMIDYSGMAFALFFLAEYINMIVISALAATLFLGGWDAPFEFLSFIPGIFWLVLK
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
IFALLSVFIWARATFPRYRYDQIMRLGWKVFLPVCVFWVIVVGFWMMSPLNIWK
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCC
>Mature Secondary Structure 
SLFDTINSGGAQLLGVAWPTVWALVRILVVAVVILLCVAYLILWERKLIGWMHVRLGPN
CCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCC
RVGPAGLLQPIADVLKLLLKEVIRPTAASRWLYLVAPVMTVVPAFAVWAVIPFQAGAVLA
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
NINAGLLYAMAISSIGVYAVILAGWASNSKYAFLGAMRAAAQMVSYEISMGFALVLVLMT
ECCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGSLNLSEIVGSQQHGFFAGHGVNFLSWNWLPLLPVFVIYFISGIAETNRHPFDVVEGES
CCCCCHHHHHCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEECCCC
EIVAGHMIDYSGMAFALFFLAEYINMIVISALAATLFLGGWDAPFEFLSFIPGIFWLVLK
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
IFALLSVFIWARATFPRYRYDQIMRLGWKVFLPVCVFWVIVVGFWMMSPLNIWK
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA