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The map label for this gene is yieH [H]

Identifier: 126453369

GI number: 126453369

Start: 862144

End: 862842

Strand: Direct

Name: yieH [H]

Synonym: BURPS1106A_0879

Alternate gene names: 126453369

Gene position: 862144-862842 (Clockwise)

Preceding gene: 126454655

Following gene: 126454613

Centisome position: 21.62

GC content: 74.11

Gene sequence:

>699_bases
ATGACGGCGCACGCGAACGACGCGCGCGTGCTCATCTGCGATTGCGACGGCGTGCTGATCGACAGCGAGACGATCGCGGC
CGACGTGCTCGTGCGCGAGCTCGAGGCGCGCTGGCCGGGCGTCGCGGCGCGGCCGATCGTGTTGCCGCTGCTCGGATTGC
GCACCGAGCGCGTGCTCGACTGCGCGAGCGCGCGCGCGGGCCGCGCGCTCGCCGATTCGGATATCGAAGCGATTCGGCGC
AGCGTCGAGGCGGCCGCGGTTCAGGCGCCGATCGTCGACGGCATCGACGCGGCGCTCGCGCGAATCGACCTGACGATCGC
ATGCGCGAGCAACAGCCGTCGGCATTACGTCGACGCCGCGCTGCGCCGCACGGGCCTCAAGCGCTTCTTCGGCGAGCGCC
TGTTCTGCGCGGACGGCGTCGCGCGGCCGAAGCCCGCGCCCGACGTCTATCTGGCCGCCGCGCAAGCGCTCGGCGTCGCG
CCGTCGCAATGTCTCGTCGTCGAGGACAGCGCGACCGGCGTGACGGCCGCGTCGGCGGCCGGCATGACGGTGCTCGGCTT
CGTCGGCGGCGGCCACGCGTCGCCGCGGCAGGTCGACGCGCTGCGCGCAATCGGCGCGCGGCGCGTGTTCGACGACATGC
GCGAGCTGCCCGGCCTCGTCTCGCGGTGGGCCGAGACGGGCGTGGTCGAGCCGCACTGA

Upstream 100 bases:

>100_bases
AGCTGTCGGCGGCGTCGCTGCTCGCGGTCGCGCCGATCCTCGTCGTCGGGTGGCTATCGCAGAAGCAGCTCGTGCGCGGC
CTCACGTTCGGGGCGGTCAA

Downstream 100 bases:

>100_bases
ACGATCGTGCCGCGCGCGCCCGACGCGCCGTGCGGCCGCACAACTGAACGGAGACAAATCATGGCAAGCGTGCTCCTGCG
CAATATCGGCAAGCGCTACG

Product: HAD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MTAHANDARVLICDCDGVLIDSETIAADVLVRELEARWPGVAARPIVLPLLGLRTERVLDCASARAGRALADSDIEAIRR
SVEAAAVQAPIVDGIDAALARIDLTIACASNSRRHYVDAALRRTGLKRFFGERLFCADGVARPKPAPDVYLAAAQALGVA
PSQCLVVEDSATGVTAASAAGMTVLGFVGGGHASPRQVDALRAIGARRVFDDMRELPGLVSRWAETGVVEPH

Sequences:

>Translated_232_residues
MTAHANDARVLICDCDGVLIDSETIAADVLVRELEARWPGVAARPIVLPLLGLRTERVLDCASARAGRALADSDIEAIRR
SVEAAAVQAPIVDGIDAALARIDLTIACASNSRRHYVDAALRRTGLKRFFGERLFCADGVARPKPAPDVYLAAAQALGVA
PSQCLVVEDSATGVTAASAAGMTVLGFVGGGHASPRQVDALRAIGARRVFDDMRELPGLVSRWAETGVVEPH
>Mature_231_residues
TAHANDARVLICDCDGVLIDSETIAADVLVRELEARWPGVAARPIVLPLLGLRTERVLDCASARAGRALADSDIEAIRRS
VEAAAVQAPIVDGIDAALARIDLTIACASNSRRHYVDAALRRTGLKRFFGERLFCADGVARPKPAPDVYLAAAQALGVAP
SQCLVVEDSATGVTAASAAGMTVLGFVGGGHASPRQVDALRAIGARRVFDDMRELPGLVSRWAETGVVEPH

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrates phosphoenolpyruvate and AMP [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1790151, Length=187, Percent_Identity=25.668449197861, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1789046, Length=177, Percent_Identity=32.2033898305085, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788021, Length=177, Percent_Identity=31.0734463276836, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 24384; Mature: 24253

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAHANDARVLICDCDGVLIDSETIAADVLVRELEARWPGVAARPIVLPLLGLRTERVLD
CCCCCCCCEEEEECCCCEEECCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCHHHHHH
CASARAGRALADSDIEAIRRSVEAAAVQAPIVDGIDAALARIDLTIACASNSRRHYVDAA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHEEEEEECCCCCHHHHHHH
LRRTGLKRFFGERLFCADGVARPKPAPDVYLAAAQALGVAPSQCLVVEDSATGVTAASAA
HHHHHHHHHHCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHC
GMTVLGFVGGGHASPRQVDALRAIGARRVFDDMRELPGLVSRWAETGVVEPH
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TAHANDARVLICDCDGVLIDSETIAADVLVRELEARWPGVAARPIVLPLLGLRTERVLD
CCCCCCCEEEEECCCCEEECCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCHHHHHH
CASARAGRALADSDIEAIRRSVEAAAVQAPIVDGIDAALARIDLTIACASNSRRHYVDAA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHEEEEEECCCCCHHHHHHH
LRRTGLKRFFGERLFCADGVARPKPAPDVYLAAAQALGVAPSQCLVVEDSATGVTAASAA
HHHHHHHHHHCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHC
GMTVLGFVGGGHASPRQVDALRAIGARRVFDDMRELPGLVSRWAETGVVEPH
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]