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The map label for this gene is degS [H]

Identifier: 126453199

GI number: 126453199

Start: 1321348

End: 1323075

Strand: Direct

Name: degS [H]

Synonym: BURPS1106A_1352

Alternate gene names: 126453199

Gene position: 1321348-1323075 (Clockwise)

Preceding gene: 126454409

Following gene: 126452071

Centisome position: 33.13

GC content: 67.36

Gene sequence:

>1728_bases
ATGGGCGAGTTGGCGGACGAATCGAGAATCTTCCTGTCGACGCTGCAGCCCGAGCGCCGCGAGCGCGGGCTCGCGATGAC
GGCCGTGGCGCTCTCGGTGGTCCTGTTCGCGACGCTCGCGCCGTTCGTGCGCATCCAGATGCCGCAGGTATGGGCGTTCA
TTCCGATCTATCAGTCGGCGATCGTGATCTGTGATCTCATCACGGCGGGCCTGCTGCTCGGTCAGTTCGGCATTTTGCGC
ACTCCGTCGCTCGTCGTGCTCGCGGGCGGCTATCTGTTCACCGCGTGCATGGCGAGCGTGCACATGCTCACGTTTCCCGG
CCTGTTCTTGCCGAGCGGCCTGCTCGACGCGGGCCCGCAGACCACCGCCTGGCTCTACATGTTCTGGCACAGCGGCTTTC
CGCTTTGCGTGATCTTCTATACGCTCGCCAGTCGACGTGAGCGCGCGGAGCCGCTCTACGCGGGGCGGCTCGCGCTGCCC
GTGATCGTTTGCATCGGTACCGCGCTCGTCGCGACGGGGGCGTTCGCCGCGCTCGCGACGAGCGGCCGCGAGCTGTTGCC
GCCGATCATGGCGAACAATCACTACACGCCGCTGATGCGCGGCGTCGTGACGACCGTCTGGCTGATGACGCTCGCCGCGC
TGATCCTGCTCACGTCGCGCCGGCCGCATTCGGTGCTCGATCTGTGGCTCATCGTCGTGCTGTGCGCGTGGCTGCTCGAC
ATCGCGCTGTCGGCCGTCCTCAATCACGGGCGTTTCGATCTCGGCTTCTACGCGGGGCGCGTTTATGGCCTCGTCGCGTC
GAGTTTCGTGCTGCTCGCGCTGTTGCTCGAAAACGGCAAGCTGTATGCGCGCACGGTCCATGCGTTGCAGGGCGAGCGCA
TCGAGCATCGGCGCGTGCAGGAGAAGACCGTCCAGTTGAACGAGGCGAACGAGTTGCTCGAGCAGCGCGTCGCCGAGCGC
ACGCGCGAGCTGCAGGCCGCGAACGACGAATTGCGGCGCGAGATCGTCGAGCGCGAGCGCGCGGAGGAAGCGCTCGCGCG
TTCGCGCGAAGAGTTGCGGGAGATCGCCGCGATCAGCTCGACCGCGCGCGAGCAGGAGCGTGGCCGGATCGCGCGCGAGC
TGCACGACGAACTCGCGCAGACGCTCGCGATGCTGCGGCTCGATCTCGAACGCGTGTCGACGACGGGCAACGAGCTCGCC
GGAAGCTTCATGGAGATGCGCGGGCTGCTCGACGGCGCGGTCGCGGCGACGCGCCGGATCGCGTCGGACCTGCGTCCGCT
GATGCTCGACGATCTCGGGCTCGTGCCGGCCATCCAGTGGCTCGTGCAGGCGTTCCAGCAGCGGCACGGTATCGATTGCA
CGCTGATCGTCGATCCGCCCGAGCTCGACCTCGTCGAGCCGCAGGCGAGCACGACGTTTCGCATCCTGCAGGAATCGCTG
ACGAACGTCGGGCGCCATGCGCGCGCATCGCATGTCGACATCCGGCTCATCGCCGACGATCGCGAGGTGATGCTGAGCGT
GCGCGACAACGGCGTCGGCTTCGATACGGAGAACCCGCGCAAGCCGAATTCGTTCGGGCTCGTCGGTTTGCGCGAGCGTG
CGTATCTGGTGCAGGGCACGCTATCGGTACAGACGGCGCCGGGGCAGGGGACGGCGATCGAGGTGCATATCCCGCTCGTG
CGCGCGCGCGAAGTCACCGTTTTGCAAAGCGGCGAGCTGCGCGAGTGA

Upstream 100 bases:

>100_bases
CGCGCTTTTCATGACGCAAGTTCGATTTCATAATAGACGCGGCGTCCGGGAACGCGCGACACGCCCGAGCGTGCAAGCTT
GCCGAATGAGGAGAACCAGC

Downstream 100 bases:

>100_bases
TGCGTTCGCGCCCGCGCGGCGCATCGCGGGTGCGGTGCGCGGGGCAGGCCCGCGCAGGCCCGCGCCGTTGAGCGGCGGGG
CGAGCGTCGCGCGATTCGGG

Product: putative membrane sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 575; Mature: 574

Protein sequence:

>575_residues
MGELADESRIFLSTLQPERRERGLAMTAVALSVVLFATLAPFVRIQMPQVWAFIPIYQSAIVICDLITAGLLLGQFGILR
TPSLVVLAGGYLFTACMASVHMLTFPGLFLPSGLLDAGPQTTAWLYMFWHSGFPLCVIFYTLASRRERAEPLYAGRLALP
VIVCIGTALVATGAFAALATSGRELLPPIMANNHYTPLMRGVVTTVWLMTLAALILLTSRRPHSVLDLWLIVVLCAWLLD
IALSAVLNHGRFDLGFYAGRVYGLVASSFVLLALLLENGKLYARTVHALQGERIEHRRVQEKTVQLNEANELLEQRVAER
TRELQAANDELRREIVERERAEEALARSREELREIAAISSTAREQERGRIARELHDELAQTLAMLRLDLERVSTTGNELA
GSFMEMRGLLDGAVAATRRIASDLRPLMLDDLGLVPAIQWLVQAFQQRHGIDCTLIVDPPELDLVEPQASTTFRILQESL
TNVGRHARASHVDIRLIADDREVMLSVRDNGVGFDTENPRKPNSFGLVGLRERAYLVQGTLSVQTAPGQGTAIEVHIPLV
RAREVTVLQSGELRE

Sequences:

>Translated_575_residues
MGELADESRIFLSTLQPERRERGLAMTAVALSVVLFATLAPFVRIQMPQVWAFIPIYQSAIVICDLITAGLLLGQFGILR
TPSLVVLAGGYLFTACMASVHMLTFPGLFLPSGLLDAGPQTTAWLYMFWHSGFPLCVIFYTLASRRERAEPLYAGRLALP
VIVCIGTALVATGAFAALATSGRELLPPIMANNHYTPLMRGVVTTVWLMTLAALILLTSRRPHSVLDLWLIVVLCAWLLD
IALSAVLNHGRFDLGFYAGRVYGLVASSFVLLALLLENGKLYARTVHALQGERIEHRRVQEKTVQLNEANELLEQRVAER
TRELQAANDELRREIVERERAEEALARSREELREIAAISSTAREQERGRIARELHDELAQTLAMLRLDLERVSTTGNELA
GSFMEMRGLLDGAVAATRRIASDLRPLMLDDLGLVPAIQWLVQAFQQRHGIDCTLIVDPPELDLVEPQASTTFRILQESL
TNVGRHARASHVDIRLIADDREVMLSVRDNGVGFDTENPRKPNSFGLVGLRERAYLVQGTLSVQTAPGQGTAIEVHIPLV
RAREVTVLQSGELRE
>Mature_574_residues
GELADESRIFLSTLQPERRERGLAMTAVALSVVLFATLAPFVRIQMPQVWAFIPIYQSAIVICDLITAGLLLGQFGILRT
PSLVVLAGGYLFTACMASVHMLTFPGLFLPSGLLDAGPQTTAWLYMFWHSGFPLCVIFYTLASRRERAEPLYAGRLALPV
IVCIGTALVATGAFAALATSGRELLPPIMANNHYTPLMRGVVTTVWLMTLAALILLTSRRPHSVLDLWLIVVLCAWLLDI
ALSAVLNHGRFDLGFYAGRVYGLVASSFVLLALLLENGKLYARTVHALQGERIEHRRVQEKTVQLNEANELLEQRVAERT
RELQAANDELRREIVERERAEEALARSREELREIAAISSTAREQERGRIARELHDELAQTLAMLRLDLERVSTTGNELAG
SFMEMRGLLDGAVAATRRIASDLRPLMLDDLGLVPAIQWLVQAFQQRHGIDCTLIVDPPELDLVEPQASTTFRILQESLT
NVGRHARASHVDIRLIADDREVMLSVRDNGVGFDTENPRKPNSFGLVGLRERAYLVQGTLSVQTAPGQGTAIEVHIPLVR
AREVTVLQSGELRE

Specific function: Involved in a sensory transduction pathway that affect the production of enzymes that degrade polymeric carbon and nitrogen sources. DegS probably acts as a kinase that phosphorylates degU [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787474, Length=238, Percent_Identity=29.4117647058824, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI87082311, Length=244, Percent_Identity=31.5573770491803, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1788812, Length=197, Percent_Identity=31.9796954314721, Blast_Score=79, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR008595
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR016381 [H]

Pfam domain/function: PF05384 DegS; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 63684; Mature: 63553

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGELADESRIFLSTLQPERRERGLAMTAVALSVVLFATLAPFVRIQMPQVWAFIPIYQSA
CCCCCCCCHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHH
IVICDLITAGLLLGQFGILRTPSLVVLAGGYLFTACMASVHMLTFPGLFLPSGLLDAGPQ
HHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCC
TTAWLYMFWHSGFPLCVIFYTLASRRERAEPLYAGRLALPVIVCIGTALVATGAFAALAT
CHHEEEEHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGRELLPPIMANNHYTPLMRGVVTTVWLMTLAALILLTSRRPHSVLDLWLIVVLCAWLLD
CCCHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
IALSAVLNHGRFDLGFYAGRVYGLVASSFVLLALLLENGKLYARTVHALQGERIEHRRVQ
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHH
EKTVQLNEANELLEQRVAERTRELQAANDELRREIVERERAEEALARSREELREIAAISS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAREQERGRIARELHDELAQTLAMLRLDLERVSTTGNELAGSFMEMRGLLDGAVAATRRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
ASDLRPLMLDDLGLVPAIQWLVQAFQQRHGIDCTLIVDPPELDLVEPQASTTFRILQESL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHH
TNVGRHARASHVDIRLIADDREVMLSVRDNGVGFDTENPRKPNSFGLVGLRERAYLVQGT
HHHHHHCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCEEECCCCEEEEEE
LSVQTAPGQGTAIEVHIPLVRAREVTVLQSGELRE
EEEEECCCCCCEEEEEECEEECCEEEEECCCCCCC
>Mature Secondary Structure 
GELADESRIFLSTLQPERRERGLAMTAVALSVVLFATLAPFVRIQMPQVWAFIPIYQSA
CCCCCCCHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHH
IVICDLITAGLLLGQFGILRTPSLVVLAGGYLFTACMASVHMLTFPGLFLPSGLLDAGPQ
HHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCC
TTAWLYMFWHSGFPLCVIFYTLASRRERAEPLYAGRLALPVIVCIGTALVATGAFAALAT
CHHEEEEHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGRELLPPIMANNHYTPLMRGVVTTVWLMTLAALILLTSRRPHSVLDLWLIVVLCAWLLD
CCCHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
IALSAVLNHGRFDLGFYAGRVYGLVASSFVLLALLLENGKLYARTVHALQGERIEHRRVQ
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHH
EKTVQLNEANELLEQRVAERTRELQAANDELRREIVERERAEEALARSREELREIAAISS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAREQERGRIARELHDELAQTLAMLRLDLERVSTTGNELAGSFMEMRGLLDGAVAATRRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
ASDLRPLMLDDLGLVPAIQWLVQAFQQRHGIDCTLIVDPPELDLVEPQASTTFRILQESL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHH
TNVGRHARASHVDIRLIADDREVMLSVRDNGVGFDTENPRKPNSFGLVGLRERAYLVQGT
HHHHHHCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCEEECCCCEEEEEE
LSVQTAPGQGTAIEVHIPLVRAREVTVLQSGELRE
EEEEECCCCCCEEEEEECEEECCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]