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The map label for this gene is bioC [C]

Identifier: 126453192

GI number: 126453192

Start: 469668

End: 470633

Strand: Direct

Name: bioC [C]

Synonym: BURPS1106A_0505

Alternate gene names: 126453192

Gene position: 469668-470633 (Clockwise)

Preceding gene: 126454783

Following gene: 126452399

Centisome position: 11.78

GC content: 71.53

Gene sequence:

>966_bases
ATGTCCCCAGCTTCCGCAAAAACCAGCCGTCCGGCCTATGATCCGCGGCGCTTGCGGCGGATCTTCGACCGCCGCGCCGC
CGCGTTCGACGCCGTGTCGTTCCTGCCGCGCGAGATCGCGCAGCGGATGCGCGAGCGCCTCGACTACATCAAGGTGAATC
CGGCGGGCGTGCTCGACGCGGGCTGCGGCACGGGCGACGACCTGCCGCTGCTGCGCGCGCGCTTCCCGCAGGCGCCCGTG
TTCGGCGTCGACGCATCGGGCGGAATGCTCGCGCGCGCGGCCGCGCGCGACACGGCCGAGACGAGCTGGCGCCGGTTCCT
GCCCGCGACGCTCACGAAAGCGCTCGGCCATCGCGGGCCGCGCGTCGCGCAAGCCGATTTCTCCGCGTTGCCGTTCGCGA
GCGGCGCGTTCGATCTGCTGTGGTCCAACTTCGCGCTGCATTGGCACGCGCGTCCCGATCTCGTGTTTCCCGAATGGCAT
CGCGTGCTGCGCGTCGACGGGCTGCTGATGTTCAGCACGCTCGGCCCCGACACGCTGCGCGAGCTGCGCGCCGCATGCGC
GGATGCCGCCGCCGCGGCGGGCGAGGCGCGCGCCGTCGCGCGCGTGATCGATTTCGTCGACATGCACGACCTGGGCGACA
TGCTCGTCGAGAGCGGCTTCGAGATTCCGGTGATGGACCAGGAGACGCTGACCGTCACGTACAAATCGCCCGATTCGCTG
CTCGCCGACGTGCGCCGTCTCGGCGCGTATCCGTTCGAGCGCGGCGCGCCGGGCCACGCGTCGCGCCGCCTGCGCGCGGC
GCTGTACGACGCGCTCGAGGCGCGCCGGCGCGACGACGGAACGATTCCGCTCACGTTCGAGGTGATCTACGGGCATGCAT
GGAAGGCGGCGCCGCGCACGACGGCGGAGGGCTTCAGCATCGTGCGCGTGCAGGACATCGGCAAAGGGCGGCCGAAGCGT
TCGTGA

Upstream 100 bases:

>100_bases
ACGGCCGGATTCGCCATCGCCGGGCTCCTACGGAGGGTCGCTTCACTGAATGGCGCGAAGCGAGCGAGTATACTTCGGGC
TCTTCGCCAGTGTGCCCGAC

Downstream 100 bases:

>100_bases
CGCGGTAAAGCGGGGTTTTCGTTATGCCGGAAATTAACGGTCGAGGGACGCTGGAAAAAGCCCCCTAAAACGGCCGGGAA
GCTTGTCGCGCTTGGCTCGC

Product: putative biotin biosynthesis protein BioC

Products: NA

Alternate protein names: Biotin Synthesis Protein BioC; Methyltransferase Type; Biotin Synthesis Protein; Methyltransferase; SAM-Dependent Methyltransferase; Biotin Synthesis Protein Bioc; Biotin Synthase BioC; UDP-N-Acetylglucosamine 1-Carboxyvinyltransferase; LOW QUALITY PROTEIN Biotin Synthesis Protein; S-Adenosyl-L-Methionine-Dependent Methyltransferases; Methyltransferase Domain-Containing Protein; BIOTIN SYNSIS METHYLTRANSFERASE BioC; Methylase Involved In Ubiquinone/Menaquinone Biosynthesis; Biotin Biosynthesis Methyltransferase BioC; Biotin Biosynthesis Protein Bioc

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MSPASAKTSRPAYDPRRLRRIFDRRAAAFDAVSFLPREIAQRMRERLDYIKVNPAGVLDAGCGTGDDLPLLRARFPQAPV
FGVDASGGMLARAAARDTAETSWRRFLPATLTKALGHRGPRVAQADFSALPFASGAFDLLWSNFALHWHARPDLVFPEWH
RVLRVDGLLMFSTLGPDTLRELRAACADAAAAAGEARAVARVIDFVDMHDLGDMLVESGFEIPVMDQETLTVTYKSPDSL
LADVRRLGAYPFERGAPGHASRRLRAALYDALEARRRDDGTIPLTFEVIYGHAWKAAPRTTAEGFSIVRVQDIGKGRPKR
S

Sequences:

>Translated_321_residues
MSPASAKTSRPAYDPRRLRRIFDRRAAAFDAVSFLPREIAQRMRERLDYIKVNPAGVLDAGCGTGDDLPLLRARFPQAPV
FGVDASGGMLARAAARDTAETSWRRFLPATLTKALGHRGPRVAQADFSALPFASGAFDLLWSNFALHWHARPDLVFPEWH
RVLRVDGLLMFSTLGPDTLRELRAACADAAAAAGEARAVARVIDFVDMHDLGDMLVESGFEIPVMDQETLTVTYKSPDSL
LADVRRLGAYPFERGAPGHASRRLRAALYDALEARRRDDGTIPLTFEVIYGHAWKAAPRTTAEGFSIVRVQDIGKGRPKR
S
>Mature_320_residues
SPASAKTSRPAYDPRRLRRIFDRRAAAFDAVSFLPREIAQRMRERLDYIKVNPAGVLDAGCGTGDDLPLLRARFPQAPVF
GVDASGGMLARAAARDTAETSWRRFLPATLTKALGHRGPRVAQADFSALPFASGAFDLLWSNFALHWHARPDLVFPEWHR
VLRVDGLLMFSTLGPDTLRELRAACADAAAAAGEARAVARVIDFVDMHDLGDMLVESGFEIPVMDQETLTVTYKSPDSLL
ADVRRLGAYPFERGAPGHASRRLRAALYDALEARRRDDGTIPLTFEVIYGHAWKAAPRTTAEGFSIVRVQDIGKGRPKRS

Specific function: Bioc Is Involved In An Early, But Chemically Unexplored, Step In The Conversion Of Pimelic Acid To Biotin. [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI40018642, Length=333, Percent_Identity=27.027027027027, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI86792933, Length=178, Percent_Identity=28.0898876404494, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17535003, Length=311, Percent_Identity=27.9742765273312, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI19922210, Length=321, Percent_Identity=26.791277258567, Blast_Score=89, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 35382; Mature: 35251

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS00136 SUBTILASE_ASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPASAKTSRPAYDPRRLRRIFDRRAAAFDAVSFLPREIAQRMRERLDYIKVNPAGVLDA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCEEC
GCGTGDDLPLLRARFPQAPVFGVDASGGMLARAAARDTAETSWRRFLPATLTKALGHRGP
CCCCCCCCCHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RVAQADFSALPFASGAFDLLWSNFALHWHARPDLVFPEWHRVLRVDGLLMFSTLGPDTLR
CCCCCCCCCCCCCCCHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCCEEECCCHHHHH
ELRAACADAAAAAGEARAVARVIDFVDMHDLGDMLVESGFEIPVMDQETLTVTYKSPDSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCEEEEEECCHHHH
LADVRRLGAYPFERGAPGHASRRLRAALYDALEARRRDDGTIPLTFEVIYGHAWKAAPRT
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCC
TAEGFSIVRVQDIGKGRPKRS
CCCCEEEEEEEECCCCCCCCC
>Mature Secondary Structure 
SPASAKTSRPAYDPRRLRRIFDRRAAAFDAVSFLPREIAQRMRERLDYIKVNPAGVLDA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCEEC
GCGTGDDLPLLRARFPQAPVFGVDASGGMLARAAARDTAETSWRRFLPATLTKALGHRGP
CCCCCCCCCHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RVAQADFSALPFASGAFDLLWSNFALHWHARPDLVFPEWHRVLRVDGLLMFSTLGPDTLR
CCCCCCCCCCCCCCCHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCCEEECCCHHHHH
ELRAACADAAAAAGEARAVARVIDFVDMHDLGDMLVESGFEIPVMDQETLTVTYKSPDSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCEEEEEECCHHHH
LADVRRLGAYPFERGAPGHASRRLRAALYDALEARRRDDGTIPLTFEVIYGHAWKAAPRT
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCC
TAEGFSIVRVQDIGKGRPKRS
CCCCEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA