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The map label for this gene is thiL [H]

Identifier: 126452891

GI number: 126452891

Start: 3383489

End: 3384490

Strand: Direct

Name: thiL [H]

Synonym: BURPS1106A_3477

Alternate gene names: 126452891

Gene position: 3383489-3384490 (Clockwise)

Preceding gene: 126452434

Following gene: 126454812

Centisome position: 84.83

GC content: 73.85

Gene sequence:

>1002_bases
GTGGCCCATCCTCCCCTTTCGGAATTTTCGTTGATCGACCGCTTCTTCGCGCGCCGCGCGACGGGGCCGCACGCGCGCGC
CGCGCTCGGCATCGGCGACGATTGCGCGCTGCTTGCACCAGAACCGGGCAAGCTGCTGGCGGTTTCGACGGACATGCTGG
TCGAAGGCCGGCACTTCCTCGCCGATGTCGATCCGCGCGCGCTCGGCCACAAGACGCTCGCCGTCAATTTGTCCGATCTC
GCCGCGATGGGCGCCGCGCCGCGCGCGTTCACGCTCGCGTGCGCGCTGCCGCGCGCCGACGCCGACTGGCTCGAGGCGTT
TTCCGACGGCCTTTTCGCGCTCGCGGAGCGCCACGGCTGCGAGCTGATCGGCGGCGACACGACGAGCGGGCCGCTCAACC
TGTGCGTCACGGTGTTCGGCGACGTCGCGTGCGGCGCCGCGTTGCGTCGAGACGCCGCACGCGACGGCGACGACGTCTGG
GTATCCGGCACGCTCGGCGATGCGCGCGCCGGCCTCGGCGTGATCCGCGGCGAATGGCGCGCGGGCGAGCGCGAGGCGGC
GGCGTTCCGGCGCGCGCTCGAATGGCCGCAACCGCGCGTCGCGCTCGGCGTCGCGCTCGCGGGCATCGCGCACGCGGCGC
TCGACGTGTCCGACGGCCTCGCGGGCGATCTGCCGCACATCCTCGAGCGCTCGAACGTGCGCGCCGACGTGGACGTCGAC
GCGGTGCCGCGCTCGGCCGCGCTCGCGACCCTGCCCGCCGACGTGCAGCGCCGCTGCATGCTCGAAGGCGGCGACGACTA
CGAGCTGTGCTTCACCGCCGCGCCGTCCGCGCGCACCGCGATCGACGCGGCCGGCGCGCGCGCGGGCGTGGCCGTCACGC
GCATCGGTACAATACGCGGCTTGTCCGCGCCGACGGACGCGCGCGCCGTGACGTGGCGCGACGCGTCGGGCGCGCCGCTT
TCCCTCACGCTGCACGGTTTCGATCATTTCCATGCCAACTGA

Upstream 100 bases:

>100_bases
AAACGTCACGAATCGGCTGCGCGCGAGCCGCCGCCGCGCCGGGCCGCGGCTCGAAGCGCCTTACAATGGGCGACATCTCA
ACGCTCGGACATCCGCGCCC

Downstream 100 bases:

>100_bases
CCCGACGCCCCGTCCGGCCGATTCCGCCGATTCCGCCAGCCAGCCCGGCGCCACGCCCGCGCCGGCCTCGTCGCCCGCGC
CGCGGCGGGATTCGCCGCAG

Product: thiamine monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MAHPPLSEFSLIDRFFARRATGPHARAALGIGDDCALLAPEPGKLLAVSTDMLVEGRHFLADVDPRALGHKTLAVNLSDL
AAMGAAPRAFTLACALPRADADWLEAFSDGLFALAERHGCELIGGDTTSGPLNLCVTVFGDVACGAALRRDAARDGDDVW
VSGTLGDARAGLGVIRGEWRAGEREAAAFRRALEWPQPRVALGVALAGIAHAALDVSDGLAGDLPHILERSNVRADVDVD
AVPRSAALATLPADVQRRCMLEGGDDYELCFTAAPSARTAIDAAGARAGVAVTRIGTIRGLSAPTDARAVTWRDASGAPL
SLTLHGFDHFHAN

Sequences:

>Translated_333_residues
MAHPPLSEFSLIDRFFARRATGPHARAALGIGDDCALLAPEPGKLLAVSTDMLVEGRHFLADVDPRALGHKTLAVNLSDL
AAMGAAPRAFTLACALPRADADWLEAFSDGLFALAERHGCELIGGDTTSGPLNLCVTVFGDVACGAALRRDAARDGDDVW
VSGTLGDARAGLGVIRGEWRAGEREAAAFRRALEWPQPRVALGVALAGIAHAALDVSDGLAGDLPHILERSNVRADVDVD
AVPRSAALATLPADVQRRCMLEGGDDYELCFTAAPSARTAIDAAGARAGVAVTRIGTIRGLSAPTDARAVTWRDASGAPL
SLTLHGFDHFHAN
>Mature_332_residues
AHPPLSEFSLIDRFFARRATGPHARAALGIGDDCALLAPEPGKLLAVSTDMLVEGRHFLADVDPRALGHKTLAVNLSDLA
AMGAAPRAFTLACALPRADADWLEAFSDGLFALAERHGCELIGGDTTSGPLNLCVTVFGDVACGAALRRDAARDGDDVWV
SGTLGDARAGLGVIRGEWRAGEREAAAFRRALEWPQPRVALGVALAGIAHAALDVSDGLAGDLPHILERSNVRADVDVDA
VPRSAALATLPADVQRRCMLEGGDDYELCFTAAPSARTAIDAAGARAGVAVTRIGTIRGLSAPTDARAVTWRDASGAPLS
LTLHGFDHFHAN

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=330, Percent_Identity=44.8484848484849, Blast_Score=236, Evalue=1e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 34716; Mature: 34584

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHPPLSEFSLIDRFFARRATGPHARAALGIGDDCALLAPEPGKLLAVSTDMLVEGRHFL
CCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEECCCCCCEEEEEHHHEECCCHHE
ADVDPRALGHKTLAVNLSDLAAMGAAPRAFTLACALPRADADWLEAFSDGLFALAERHGC
ECCCCHHHCCEEEEEEHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCC
ELIGGDTTSGPLNLCVTVFGDVACGAALRRDAARDGDDVWVSGTLGDARAGLGVIRGEWR
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHCCEEEECCCC
AGEREAAAFRRALEWPQPRVALGVALAGIAHAALDVSDGLAGDLPHILERSNVRADVDVD
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCC
AVPRSAALATLPADVQRRCMLEGGDDYELCFTAAPSARTAIDAAGARAGVAVTRIGTIRG
CCCCCHHEEECCHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHCCCCCCEEEEEEEHCCC
LSAPTDARAVTWRDASGAPLSLTLHGFDHFHAN
CCCCCCCCEEEEECCCCCEEEEEEECCCCCCCC
>Mature Secondary Structure 
AHPPLSEFSLIDRFFARRATGPHARAALGIGDDCALLAPEPGKLLAVSTDMLVEGRHFL
CCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEECCCCCCEEEEEHHHEECCCHHE
ADVDPRALGHKTLAVNLSDLAAMGAAPRAFTLACALPRADADWLEAFSDGLFALAERHGC
ECCCCHHHCCEEEEEEHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCC
ELIGGDTTSGPLNLCVTVFGDVACGAALRRDAARDGDDVWVSGTLGDARAGLGVIRGEWR
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHCCEEEECCCC
AGEREAAAFRRALEWPQPRVALGVALAGIAHAALDVSDGLAGDLPHILERSNVRADVDVD
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCC
AVPRSAALATLPADVQRRCMLEGGDDYELCFTAAPSARTAIDAAGARAGVAVTRIGTIRG
CCCCCHHEEECCHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHCCCCCCEEEEEEEHCCC
LSAPTDARAVTWRDASGAPLSLTLHGFDHFHAN
CCCCCCCCEEEEECCCCCEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]