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The map label for this gene is rppH

Identifier: 126452879

GI number: 126452879

Start: 3426322

End: 3426972

Strand: Direct

Name: rppH

Synonym: BURPS1106A_3521

Alternate gene names: 126452879

Gene position: 3426322-3426972 (Clockwise)

Preceding gene: 126453542

Following gene: 126454047

Centisome position: 85.91

GC content: 63.9

Gene sequence:

>651_bases
ATGCTGGATCGTGAAGGCTTTCGCCCGAACGTCGGCATCATCCTCTTGAACGCGCACAACGAGGTGTTTTGGGGCAAACG
GCTCCGCGAGCATTCCTGGCAGTTTCCGCAAGGGGGCATCAAGTACGGCGAGACCCCGATGCAAGCGATGTACAGGGAAC
TGCACGAGGAGACCGGGCTGCTGCCGGAACACGTCAAGATCATCGGCCGCACTCGCGACTGGTTGCGTTATGAGGTGCCA
GACAAGTTCATCAAGCGCGAAGTGCGCGGCCATTATCGCGGCCAGAAGCAGATCTGGTTCCTGCTGCGAATGGTCGGCCG
CGATTGCGACATCTGCCTGCGGGCGACGGATCATCCGGAGTTCGACGCGTGGCGCTGGAACGAATACTGGGTGCCACTCG
ACGCGGTGATCGAGTTCAAGCGGGATGTGTATCAGTTGGCGTTGACCGAACTGTCGCGTTTCCTGCGCCGCCCGGCGCAG
CGCACCGACAAATCGCGCGGCCCGCGCGCGCCGCGCTATCCGCGTGTCGCGAATGGGCACGCGGCATCGGAGGCACCGGC
CGCGATCGACACGTCGGCAGTCTGTTCGGAAGTCGAGCCGGGCGCGAACGCGCTCGACGAAACCCCTCCCCGCGTGAGTC
TGCGCGACTGA

Upstream 100 bases:

>100_bases
TGTAGTTGACACGCTCCGCCCGGATTCGCTCCGTTCCGGTGCGCAACGCCCGTTATCTGTTTATAATCAAAGCAATTTTA
AAGGATTCGAAGGTGGTTGT

Downstream 100 bases:

>100_bases
CGCGCGGGCTGGTTCGACGGGAATGAAAACGCATGACCGGGCGCGGCATTGAAGGATGCCGCGCCTTTTTTACGAGGCAC
CCATATTGAAAGCGATTGCT

Product: dinucleoside polyphosphate hydrolase

Products: NA

Alternate protein names: (Di)nucleoside polyphosphate hydrolase

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MLDREGFRPNVGIILLNAHNEVFWGKRLREHSWQFPQGGIKYGETPMQAMYRELHEETGLLPEHVKIIGRTRDWLRYEVP
DKFIKREVRGHYRGQKQIWFLLRMVGRDCDICLRATDHPEFDAWRWNEYWVPLDAVIEFKRDVYQLALTELSRFLRRPAQ
RTDKSRGPRAPRYPRVANGHAASEAPAAIDTSAVCSEVEPGANALDETPPRVSLRD

Sequences:

>Translated_216_residues
MLDREGFRPNVGIILLNAHNEVFWGKRLREHSWQFPQGGIKYGETPMQAMYRELHEETGLLPEHVKIIGRTRDWLRYEVP
DKFIKREVRGHYRGQKQIWFLLRMVGRDCDICLRATDHPEFDAWRWNEYWVPLDAVIEFKRDVYQLALTELSRFLRRPAQ
RTDKSRGPRAPRYPRVANGHAASEAPAAIDTSAVCSEVEPGANALDETPPRVSLRD
>Mature_216_residues
MLDREGFRPNVGIILLNAHNEVFWGKRLREHSWQFPQGGIKYGETPMQAMYRELHEETGLLPEHVKIIGRTRDWLRYEVP
DKFIKREVRGHYRGQKQIWFLLRMVGRDCDICLRATDHPEFDAWRWNEYWVPLDAVIEFKRDVYQLALTELSRFLRRPAQ
RTDKSRGPRAPRYPRVANGHAASEAPAAIDTSAVCSEVEPGANALDETPPRVSLRD

Specific function: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain

Homologues:

Organism=Escherichia coli, GI1789194, Length=175, Percent_Identity=45.1428571428571, Blast_Score=173, Evalue=7e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPPH_BURM7 (A3MR94)

Other databases:

- EMBL:   CP000548
- RefSeq:   YP_001082780.1
- ProteinModelPortal:   A3MR94
- SMR:   A3MR94
- GeneID:   4892959
- GenomeReviews:   CP000548_GR
- KEGG:   bmn:BMA10247_3264
- TIGR:   BMA10247_3264
- HOGENOM:   HBG302451
- OMA:   GQKQIWY
- ProtClustDB:   PRK00714
- BioCyc:   BMAL320389:BMA10247_3264-MONOMER
- HAMAP:   MF_00298
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR022927
- Gene3D:   G3DSA:3.90.79.10
- PRINTS:   PR00502

Pfam domain/function: PF00293 NUDIX; SSF55811 NUDIX_hydrolase

EC number: 3.6.1.- [C]

Molecular weight: Translated: 25263; Mature: 25263

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS51462 NUDIX; PS00893 NUDIX_BOX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDREGFRPNVGIILLNAHNEVFWGKRLREHSWQFPQGGIKYGETPMQAMYRELHEETGL
CCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
LPEHVKIIGRTRDWLRYEVPDKFIKREVRGHYRGQKQIWFLLRMVGRDCDICLRATDHPE
CHHHHHHHHCCHHHHEECCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEECCCCCC
FDAWRWNEYWVPLDAVIEFKRDVYQLALTELSRFLRRPAQRTDKSRGPRAPRYPRVANGH
CCCEECCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
AASEAPAAIDTSAVCSEVEPGANALDETPPRVSLRD
CCCCCCCHHHHHHHHHHCCCCCCHHCCCCCCCCCCC
>Mature Secondary Structure
MLDREGFRPNVGIILLNAHNEVFWGKRLREHSWQFPQGGIKYGETPMQAMYRELHEETGL
CCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
LPEHVKIIGRTRDWLRYEVPDKFIKREVRGHYRGQKQIWFLLRMVGRDCDICLRATDHPE
CHHHHHHHHCCHHHHEECCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEECCCCCC
FDAWRWNEYWVPLDAVIEFKRDVYQLALTELSRFLRRPAQRTDKSRGPRAPRYPRVANGH
CCCEECCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
AASEAPAAIDTSAVCSEVEPGANALDETPPRVSLRD
CCCCCCCHHHHHHHHHHCCCCCCHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA