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The map label for this gene is htpX [H]

Identifier: 126452704

GI number: 126452704

Start: 153720

End: 154577

Strand: Direct

Name: htpX [H]

Synonym: BURPS1106A_0163

Alternate gene names: 126452704

Gene position: 153720-154577 (Clockwise)

Preceding gene: 126451862

Following gene: 126454661

Centisome position: 3.85

GC content: 65.15

Gene sequence:

>858_bases
ATGTTCAATTGGGTCAAAACGGCGATGCTGATGGCCGCGATCACGGCCCTGTTCATCGTGATCGGCGGCATGATCGGCGG
ATCGCGCGGGATGACGATCGCGTTGCTGATCGCGCTCGGGATGAATTTCTTCTCATACTGGTTCTCCGACAAGATGGTGC
TGCGCATGTACAACGCGCAGGAAGTCGACGAGGCCACGGCGCCGCAGTTCTATCGGATGGTGCGCGAACTTGCGACGCGC
GCGAACTTGCCGATGCCGCGCGTTTATCTGATCGACGAGAACCAGCCGAACGCGTTTGCGACCGGCCGCAATCCCGAGCA
CGCGGCCGTCGCCGCGACGACGGGCATCCTGCGTGTGCTGTCCGAGCGCGAGATGCGGGGCGTGATGGCGCACGAGCTTG
CGCACGTGAAGCATCGCGACATCCTGATCTCGACGATTTCGGCGACGATGGCGGGCGCGATCTCGGCGCTCGCGAATTTC
GCGATGTTCTTCGGCGGGCGCGACGAGAATGGCCGGCCGGCAAATCCGATCGCGGGCATCGCGGTCGCGCTGCTGGCGCC
GATCGCGGGCGCGCTGATTCAGATGGCGATTTCGCGTGCGCGCGAATTCGAGGCGGACCGCGGCGGCGCGCAGATCTCGG
GCGATCCGCAGGCGCTTGCCTCAGCGCTCGACAAGATCCACCGCTATGCGTCGGGCATTCCGTTTCAGACAGCCGAGGAG
CATCCGGCCACCGCGCAGATGATGATCATGAATCCGCTGTCGGGCGGTGGGCTGCAGAATCTGTTCTCGACGCACCCCGC
CACCGAGGAGCGGATCGCGCGGCTGATGGACATGGCGCGCACCGGCCGCTTCGACTGA

Upstream 100 bases:

>100_bases
TTTCTCGAAACGTTCTTATCTAACAGATCGCTTACAATCATGCGCCGCCGCCGCTCGCGCGTGCGGTGCGATCCCCGCAG
ACGGATAAGGAGTGGGAAAC

Downstream 100 bases:

>100_bases
CGAACGCCGTTGCCGGCGACGCGCGCGGGAGGTTGCGGCATCGGCGGCCGGTCTCGACGGGCTTCGCCGTATCCGGCGAT
CGACCGAGCCCCGCATGCGT

Product: M48 family peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MFNWVKTAMLMAAITALFIVIGGMIGGSRGMTIALLIALGMNFFSYWFSDKMVLRMYNAQEVDEATAPQFYRMVRELATR
ANLPMPRVYLIDENQPNAFATGRNPEHAAVAATTGILRVLSEREMRGVMAHELAHVKHRDILISTISATMAGAISALANF
AMFFGGRDENGRPANPIAGIAVALLAPIAGALIQMAISRAREFEADRGGAQISGDPQALASALDKIHRYASGIPFQTAEE
HPATAQMMIMNPLSGGGLQNLFSTHPATEERIARLMDMARTGRFD

Sequences:

>Translated_285_residues
MFNWVKTAMLMAAITALFIVIGGMIGGSRGMTIALLIALGMNFFSYWFSDKMVLRMYNAQEVDEATAPQFYRMVRELATR
ANLPMPRVYLIDENQPNAFATGRNPEHAAVAATTGILRVLSEREMRGVMAHELAHVKHRDILISTISATMAGAISALANF
AMFFGGRDENGRPANPIAGIAVALLAPIAGALIQMAISRAREFEADRGGAQISGDPQALASALDKIHRYASGIPFQTAEE
HPATAQMMIMNPLSGGGLQNLFSTHPATEERIARLMDMARTGRFD
>Mature_285_residues
MFNWVKTAMLMAAITALFIVIGGMIGGSRGMTIALLIALGMNFFSYWFSDKMVLRMYNAQEVDEATAPQFYRMVRELATR
ANLPMPRVYLIDENQPNAFATGRNPEHAAVAATTGILRVLSEREMRGVMAHELAHVKHRDILISTISATMAGAISALANF
AMFFGGRDENGRPANPIAGIAVALLAPIAGALIQMAISRAREFEADRGGAQISGDPQALASALDKIHRYASGIPFQTAEE
HPATAQMMIMNPLSGGGLQNLFSTHPATEERIARLMDMARTGRFD

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=272, Percent_Identity=30.5147058823529, Blast_Score=99, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 30929; Mature: 30929

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
7.0 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
7.0 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNWVKTAMLMAAITALFIVIGGMIGGSRGMTIALLIALGMNFFSYWFSDKMVLRMYNAQ
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCHH
EVDEATAPQFYRMVRELATRANLPMPRVYLIDENQPNAFATGRNPEHAAVAATTGILRVL
HHHHHCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEECCCCCCHHHHHHHHHHHHHH
SEREMRGVMAHELAHVKHRDILISTISATMAGAISALANFAMFFGGRDENGRPANPIAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
AVALLAPIAGALIQMAISRAREFEADRGGAQISGDPQALASALDKIHRYASGIPFQTAEE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
HPATAQMMIMNPLSGGGLQNLFSTHPATEERIARLMDMARTGRFD
CCCCEEEEEECCCCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFNWVKTAMLMAAITALFIVIGGMIGGSRGMTIALLIALGMNFFSYWFSDKMVLRMYNAQ
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCHH
EVDEATAPQFYRMVRELATRANLPMPRVYLIDENQPNAFATGRNPEHAAVAATTGILRVL
HHHHHCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEECCCCCCHHHHHHHHHHHHHH
SEREMRGVMAHELAHVKHRDILISTISATMAGAISALANFAMFFGGRDENGRPANPIAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
AVALLAPIAGALIQMAISRAREFEADRGGAQISGDPQALASALDKIHRYASGIPFQTAEE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
HPATAQMMIMNPLSGGGLQNLFSTHPATEERIARLMDMARTGRFD
CCCCEEEEEECCCCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA