Click here to switch to the map view.

The map label for this gene is aspS [H]

Identifier: 126452649

GI number: 126452649

Start: 664565

End: 666367

Strand: Direct

Name: aspS [H]

Synonym: BURPS1106A_0691

Alternate gene names: 126452649

Gene position: 664565-666367 (Clockwise)

Preceding gene: 126455087

Following gene: 126453806

Centisome position: 16.66

GC content: 66.33

Gene sequence:

>1803_bases
ATGTCGATGCGAACTGAATACTGCGGTCTCGTGACCGAACACCTGCTGGGCCAGACGGTGTCGCTGTGCGGCTGGGTCCA
TCGTCGCCGCGATCACGGCGGCGTGATCTTCATCGATCTGCGCGATCGCGAGGGCCTCGTGCAGGTGGTGTGCGATCCGG
ATCGCGCCGAGATGTTCGCGGCCGCCGAAGGCGTGCGCAACGAGTTTTGCATCCAGGTGAAGGGCCTCGTGCGCGGCCGT
CCGGAAGGCACGATCAACGCGGGCCTGAAGAGCGGCAGGATCGAGGTGCTGTGCCACGAGCTCAACGTGCTGAACGCGTC
GGTCACGCCGCCGTTCCAGCTCGACGACGACAACCTGTCGGAGACGACGCGCCTCACGCACCGCGTGCTCGACCTGCGCC
GCCCGCAGATGCAGCACAACCTGCGGCTGCGCTACCGCGTCGCGATCGAGGCGCGCAAGTATCTCGACGAGCAGGGCTTC
ATCGACATCGAAACGCCGATGCTCACGAAGAGCACGCCGGAAGGCGCGCGCGACTACCTCGTGCCGTCGCGCGTGAACGC
GGGCCAGTTCTTCGCGCTGCCGCAGTCGCCGCAGCTGTTCAAGCAGCTCTTGATGGTGGCGAACTTCGATCGCTACTACC
AGATCACGAAGTGCTTCCGCGACGAAGACCTGCGCGCGGATCGCCAGCCCGAATTCACGCAGATCGACTGCGAGACGTCG
TTCCTCGGCGAGCAGGAAATCCGCGATCTGTTCGAGGACATGATCCGCCACATCTTCAAGACGACGATCGGCGTCGAGCT
GGACGCGACCTTCCCGGTGATGCCGTACTCGGAGGCGATGGCGCGCTTCGGCTCGGACAAGCCGGACCTGCGCGTGAAGC
TCGAGTTCACCGAGCTCACCGATGCGATGAAGGACGTCGATTTCAAGGTGTTCAGCACGCCGGCCAACACGAAGGACGGC
CGCGTCGCGGCACTGCGCGTGCCGAAGGGCGGCGAGCTCACGCGCGGCGACATCGACGGCTACACCGAATTCGTGCGCAT
CTACGGCGCGAAGGGCCTCGCGTGGATCAAGGTCAACGAGCGCGCGAAGGGCCGCGACGGCCTGCAGAGCCCGATCGTGA
AGAACCTGCACGACGCGTCGATCGCGGCGATCCTCGAGCGCACGGGCGCGCAGGACGGCGACATCATCTTCTTCGCGGCC
GACCGCGCGAAGGTCGTCAACGACAGCCTCGGCGCGCTGCGCCTGAAGATCGGCCACTCGGAATTCGGCAAGGCGAACGG
CCTTGTCGAAGCGGGCTGGAAGCCGCTGTGGGTCGTCGATTTCCCGATGTTCGAATACGACGACGAGGAAGCGCGCTATG
TCGCCGCGCACCATCCGTTCACGAGCCCGAAGGACGAGCATCTCGAATACCTCGAGACCGATCCGGGCCGCTGCCTCGCG
AAGGCGTACGACATGGTGCTCAACGGCTGGGAGATCGGCGGCGGCTCGGTGCGTATCCACCGCGAGGAAGTGCAGAGCAA
GGTGTTCCGCGCGCTGAAGATCGGCCCGGAAGAGGCGCAGGCGAAGTTCGGCTTCCTGCTCGACGCGCTGCAGTACGGCG
CGCCGCCGCACGGCGGGATCGCGTTCGGCCTCGATCGCATCGTCACGATGATGGCGGGCGCCGATTCGATCCGCGACGTG
ATCGCGTTCCCGAAGACGCAGCGCGCGCAGTGCCTGCTCACGCAGGCGCCGAGCCCCGTCGACGAGCGCCAGTTGCGCGA
GCTGCACATCCGCCTGCGCCAGCCGGAGCAGCCGAAGGCGTAA

Upstream 100 bases:

>100_bases
CCGTTGCCGCGCCGGCGCGCCGCCCCGTCGAGCCGCCGATGTAATGCCCGGGAGAGAGTGCGGCTCTTCCCGTTGACCAC
TACGAAAGAAAGCAAACATC

Downstream 100 bases:

>100_bases
CGCGGGCCGCGCCCGGCCGCGGGCCGAACCGGGATGCCGGCTCGGCGTCGCGCCCGGCGTGCCGGCCGTTTCGGCCGATG
CCGACGGGAACCGCAGAAAG

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS [H]

Number of amino acids: Translated: 600; Mature: 599

Protein sequence:

>600_residues
MSMRTEYCGLVTEHLLGQTVSLCGWVHRRRDHGGVIFIDLRDREGLVQVVCDPDRAEMFAAAEGVRNEFCIQVKGLVRGR
PEGTINAGLKSGRIEVLCHELNVLNASVTPPFQLDDDNLSETTRLTHRVLDLRRPQMQHNLRLRYRVAIEARKYLDEQGF
IDIETPMLTKSTPEGARDYLVPSRVNAGQFFALPQSPQLFKQLLMVANFDRYYQITKCFRDEDLRADRQPEFTQIDCETS
FLGEQEIRDLFEDMIRHIFKTTIGVELDATFPVMPYSEAMARFGSDKPDLRVKLEFTELTDAMKDVDFKVFSTPANTKDG
RVAALRVPKGGELTRGDIDGYTEFVRIYGAKGLAWIKVNERAKGRDGLQSPIVKNLHDASIAAILERTGAQDGDIIFFAA
DRAKVVNDSLGALRLKIGHSEFGKANGLVEAGWKPLWVVDFPMFEYDDEEARYVAAHHPFTSPKDEHLEYLETDPGRCLA
KAYDMVLNGWEIGGGSVRIHREEVQSKVFRALKIGPEEAQAKFGFLLDALQYGAPPHGGIAFGLDRIVTMMAGADSIRDV
IAFPKTQRAQCLLTQAPSPVDERQLRELHIRLRQPEQPKA

Sequences:

>Translated_600_residues
MSMRTEYCGLVTEHLLGQTVSLCGWVHRRRDHGGVIFIDLRDREGLVQVVCDPDRAEMFAAAEGVRNEFCIQVKGLVRGR
PEGTINAGLKSGRIEVLCHELNVLNASVTPPFQLDDDNLSETTRLTHRVLDLRRPQMQHNLRLRYRVAIEARKYLDEQGF
IDIETPMLTKSTPEGARDYLVPSRVNAGQFFALPQSPQLFKQLLMVANFDRYYQITKCFRDEDLRADRQPEFTQIDCETS
FLGEQEIRDLFEDMIRHIFKTTIGVELDATFPVMPYSEAMARFGSDKPDLRVKLEFTELTDAMKDVDFKVFSTPANTKDG
RVAALRVPKGGELTRGDIDGYTEFVRIYGAKGLAWIKVNERAKGRDGLQSPIVKNLHDASIAAILERTGAQDGDIIFFAA
DRAKVVNDSLGALRLKIGHSEFGKANGLVEAGWKPLWVVDFPMFEYDDEEARYVAAHHPFTSPKDEHLEYLETDPGRCLA
KAYDMVLNGWEIGGGSVRIHREEVQSKVFRALKIGPEEAQAKFGFLLDALQYGAPPHGGIAFGLDRIVTMMAGADSIRDV
IAFPKTQRAQCLLTQAPSPVDERQLRELHIRLRQPEQPKA
>Mature_599_residues
SMRTEYCGLVTEHLLGQTVSLCGWVHRRRDHGGVIFIDLRDREGLVQVVCDPDRAEMFAAAEGVRNEFCIQVKGLVRGRP
EGTINAGLKSGRIEVLCHELNVLNASVTPPFQLDDDNLSETTRLTHRVLDLRRPQMQHNLRLRYRVAIEARKYLDEQGFI
DIETPMLTKSTPEGARDYLVPSRVNAGQFFALPQSPQLFKQLLMVANFDRYYQITKCFRDEDLRADRQPEFTQIDCETSF
LGEQEIRDLFEDMIRHIFKTTIGVELDATFPVMPYSEAMARFGSDKPDLRVKLEFTELTDAMKDVDFKVFSTPANTKDGR
VAALRVPKGGELTRGDIDGYTEFVRIYGAKGLAWIKVNERAKGRDGLQSPIVKNLHDASIAAILERTGAQDGDIIFFAAD
RAKVVNDSLGALRLKIGHSEFGKANGLVEAGWKPLWVVDFPMFEYDDEEARYVAAHHPFTSPKDEHLEYLETDPGRCLAK
AYDMVLNGWEIGGGSVRIHREEVQSKVFRALKIGPEEAQAKFGFLLDALQYGAPPHGGIAFGLDRIVTMMAGADSIRDVI
AFPKTQRAQCLLTQAPSPVDERQLRELHIRLRQPEQPKA

Specific function: Unknown

COG id: COG0173

COG function: function code J; Aspartyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI40789249, Length=612, Percent_Identity=38.2352941176471, Blast_Score=410, Evalue=1e-114,
Organism=Homo sapiens, GI45439306, Length=280, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI194272210, Length=254, Percent_Identity=24.4094488188976, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI5031815, Length=254, Percent_Identity=24.4094488188976, Blast_Score=80, Evalue=5e-15,
Organism=Escherichia coli, GI1788173, Length=591, Percent_Identity=58.3756345177665, Blast_Score=701, Evalue=0.0,
Organism=Escherichia coli, GI1789256, Length=268, Percent_Identity=25.7462686567164, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1790571, Length=254, Percent_Identity=25.5905511811024, Blast_Score=77, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI32566633, Length=617, Percent_Identity=34.3598055105348, Blast_Score=321, Evalue=6e-88,
Organism=Caenorhabditis elegans, GI71994340, Length=298, Percent_Identity=22.8187919463087, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17535927, Length=298, Percent_Identity=22.8187919463087, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17535925, Length=298, Percent_Identity=22.8187919463087, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17551876, Length=262, Percent_Identity=25.5725190839695, Blast_Score=80, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6325153, Length=300, Percent_Identity=36.3333333333333, Blast_Score=171, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6323011, Length=259, Percent_Identity=28.957528957529, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320242, Length=266, Percent_Identity=25.5639097744361, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324256, Length=270, Percent_Identity=25.5555555555556, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24584738, Length=607, Percent_Identity=35.7495881383855, Blast_Score=347, Evalue=2e-95,
Organism=Drosophila melanogaster, GI17136276, Length=264, Percent_Identity=29.9242424242424, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24640849, Length=258, Percent_Identity=26.7441860465116, Blast_Score=84, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24640851, Length=258, Percent_Identity=26.7441860465116, Blast_Score=83, Evalue=4e-16,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020564
- InterPro:   IPR004524
- InterPro:   IPR018153
- InterPro:   IPR002312
- InterPro:   IPR004115
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02938 GAD; PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.12 [H]

Molecular weight: Translated: 67681; Mature: 67550

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMRTEYCGLVTEHLLGQTVSLCGWVHRRRDHGGVIFIDLRDREGLVQVVCDPDRAEMFA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCHHHHHH
AAEGVRNEFCIQVKGLVRGRPEGTINAGLKSGRIEVLCHELNVLNASVTPPFQLDDDNLS
HHHCCCCCEEEEEEHHHCCCCCCCEECCCCCCCEEEEEEEHHEEECCCCCCCEECCCCCH
ETTRLTHRVLDLRRPQMQHNLRLRYRVAIEARKYLDEQGFIDIETPMLTKSTPEGARDYL
HHHHHHHHHHHHCCCHHHCCCEEEEEEEEHHHHHCCCCCCEEECCCCCCCCCCCCCHHCC
VPSRVNAGQFFALPQSPQLFKQLLMVANFDRYYQITKCFRDEDLRADRQPEFTQIDCETS
CCCCCCCCEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEECCHH
FLGEQEIRDLFEDMIRHIFKTTIGVELDATFPVMPYSEAMARFGSDKPDLRVKLEFTELT
HCCHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCHHHHHHHHCCCCCCEEEEEEHHHHH
DAMKDVDFKVFSTPANTKDGRVAALRVPKGGELTRGDIDGYTEFVRIYGAKGLAWIKVNE
HHHHCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECC
RAKGRDGLQSPIVKNLHDASIAAILERTGAQDGDIIFFAADRAKVVNDSLGALRLKIGHS
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHCCCCCEEEEEECCC
EFGKANGLVEAGWKPLWVVDFPMFEYDDEEARYVAAHHPFTSPKDEHLEYLETDPGRCLA
CCCCCCCEEECCCCEEEEEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHCCCCCHHHH
KAYDMVLNGWEIGGGSVRIHREEVQSKVFRALKIGPEEAQAKFGFLLDALQYGAPPHGGI
HHHHHHHCCEEECCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCH
AFGLDRIVTMMAGADSIRDVIAFPKTQRAQCLLTQAPSPVDERQLRELHIRLRQPEQPKA
HHHHHHHHHHHHCHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SMRTEYCGLVTEHLLGQTVSLCGWVHRRRDHGGVIFIDLRDREGLVQVVCDPDRAEMFA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCHHHHHH
AAEGVRNEFCIQVKGLVRGRPEGTINAGLKSGRIEVLCHELNVLNASVTPPFQLDDDNLS
HHHCCCCCEEEEEEHHHCCCCCCCEECCCCCCCEEEEEEEHHEEECCCCCCCEECCCCCH
ETTRLTHRVLDLRRPQMQHNLRLRYRVAIEARKYLDEQGFIDIETPMLTKSTPEGARDYL
HHHHHHHHHHHHCCCHHHCCCEEEEEEEEHHHHHCCCCCCEEECCCCCCCCCCCCCHHCC
VPSRVNAGQFFALPQSPQLFKQLLMVANFDRYYQITKCFRDEDLRADRQPEFTQIDCETS
CCCCCCCCEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEECCHH
FLGEQEIRDLFEDMIRHIFKTTIGVELDATFPVMPYSEAMARFGSDKPDLRVKLEFTELT
HCCHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCHHHHHHHHCCCCCCEEEEEEHHHHH
DAMKDVDFKVFSTPANTKDGRVAALRVPKGGELTRGDIDGYTEFVRIYGAKGLAWIKVNE
HHHHCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECC
RAKGRDGLQSPIVKNLHDASIAAILERTGAQDGDIIFFAADRAKVVNDSLGALRLKIGHS
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHCCCCCEEEEEECCC
EFGKANGLVEAGWKPLWVVDFPMFEYDDEEARYVAAHHPFTSPKDEHLEYLETDPGRCLA
CCCCCCCEEECCCCEEEEEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHCCCCCHHHH
KAYDMVLNGWEIGGGSVRIHREEVQSKVFRALKIGPEEAQAKFGFLLDALQYGAPPHGGI
HHHHHHHCCEEECCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCH
AFGLDRIVTMMAGADSIRDVIAFPKTQRAQCLLTQAPSPVDERQLRELHIRLRQPEQPKA
HHHHHHHHHHHHCHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA