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The map label for this gene is yciR [C]

Identifier: 126452559

GI number: 126452559

Start: 1138925

End: 1141243

Strand: Reverse

Name: yciR [C]

Synonym: BURPS1106A_1160

Alternate gene names: 126452559

Gene position: 1141243-1138925 (Counterclockwise)

Preceding gene: 126452320

Following gene: 126454264

Centisome position: 28.61

GC content: 66.45

Gene sequence:

>2319_bases
GTGCGCGCGACACGCAAGTCGCGCCGCCGCCGCGCGCTGTTCGCGATTCCGCTCCTCGGCACGCTGGCGCTCGCGCTGCT
GTGGGTGGCCATCATCGCGCGCCTGTCCGTCGAGAAGGACAGCGCGTTCCGCGATGCGGGCGCGTCGGCCGCGATCCTGT
CGACGGCGCTCGAGCAGCACACGGTCAAGGCGATCCATCAGGTCGACCAGATCACCCGCTTCGTCAAATACGAATTCGAG
AAGTCGCCCACCCGCTTCAACCTTGCGAGCACGGTGGAGAAAGGCGTGGTGCCGAGCGACACGCTGATCCAAGTGTCCAT
CCTCGATGCGCGCGGCCGGCTCGTCGCGAACACGGCCGAGGCGCATCCGAAGCCGATCGATCTGTCCGACCGCGAGCACT
TCAAGGTGCACATGCAGCGCAACGACGACGATCTCTACATCAGCAAGCCGGTGTTCGGCCGCGTGTCGCGCCACTGGACG
CTGCAGATGACGCGGCGCCTGAACCATCCGGACGGCTCGTTCGCCGGCGTGGTCGTCGTGTCCGAGGATCCGGCCTACTT
CACGAACGACTTCTACAACAACGCGACGCTCGGCAAGGACGGCGTGATCGCGGTGATCTCGGATACGGGCGCCGTGCTCG
CGCGCAGCACGGGCTCCACGCAGAAGACGCCCGGCACGTTCTCGGCATCGGGCGTCTACCCGGTGTCGGAGCGCGCCTCG
GGCACCTATGTCGATCCGATCGACGGCATCGTGCGCATCGTGTCGTATCGCCATCTCGACGGCTATCCGCTCGGCGTGAT
GGTGGGCCTGTCGCAGGCTGAAGAATTCGCCGACTACCACCACACGCGCAATGTCTATCTGCTGATGACGGGCTTCATCA
CGCTCGCGATGCTCGCGTTCTTCGGCGTCGCGACGGGCCTGATCGGCAAGCTGCTCGGCCGCGAGCGCGAAATGACGCAG
CTCGCCGAGTTCGATCTGCTGACGGGGCTTGCGAACCGCTATGCGACGCTGCGCAGCCTGCGCAACGACGTCGCGCTGCC
GTCGAATCTGTCGCGCCTCGCGATCCTGTTCATCGATCTCGACAATTTCAAGACCGTCAACGACACGCTCGGCCACAACG
CGGGCGACATCGTGCTGCAGATGACGGCCGCGCGCCTGTCCGATGCGGTGGCGAACGAAGGCGCGCTCGCGCGCATCGGC
GGCGACGAGTTCGTCGTCGTCGTGAAGGGCGAGAACGTCGAGCGGCGCGCCGAGCGGCTCGCGGAGGCGATCGTGCGAAT
GTTCGCCGAGCCGTTCGACGTGCGCGGCAGCTCGTTCGTGCTGCACGCGAGCATCGGCATCGCGCTGCATTCGGTGGAGA
ACGAAAGCGAGATCGACTTGCTGAAGAAGGCCGATCTCGCGATGTACAGCGCCAAGGACGCCGGCAAGAACTGCTACCAG
TTCTATGCGCCGCACTTGTCGCACCGCGCCGATCACCTGATGCGCTGGGAGCAGCAGTTGCGCGTCGCGCTGTCGGACGG
GCAACTGTTCCTCGCCTACCAGCCGAAGATCGATCTCACGTACCGCTGCATCACCGGCTTCGAGGCGCTCGTGCGCTGGG
ACCATCCGGAGCACGGCGTGATCTCCGCGAACGAATTCATTTCGATCGCCGAATCGACCGGGCTCATCGTGCCGATCGGC
GACTTCGTGATCCGCACCGCGTGCGAGCAGCTCGCGCGCTGGCGCAACGAGGGCCACGACAAGCTCACGCTCGCCGTCAA
TATCTCGCCCGTGCAGTTCTGGCGCGGCGACCTGATCGACACGATCTCGCGCGCGCTCGCCGAGACCGGAATCGAGGCGC
GCCGCCTCGAGCTCGAGATCACCGAGACCGCGATGATGGAATACCCTGAGCTCGTATCGGAGAAGATCGTCGCGCTGAAA
AGGCTCGGGATCCGCGTCGCGCTCGACGATTTCGGCACCGGCTATTCGTCGCTGTCCTACCTGCACCGCTTCGCGGTCGA
CACGCTGAAGGTCGACCGCTCGTTCATCCAGGCGATTCCGGCCGACCGCAGCGTGTGCGTGATGGTGTCGTCGATCGTGC
ACCTCGCGCGCTCGCTCGGGCTCACGGTCGTCGTCGAGGGGACGGAGACGGAGGAGCAGATCGCGTGGCTTGCCGCGCTC
GGGCGCATCGAGGCGCAAGGCTTCCTGTTCTCGCGGCCGGTGCCCTCCGACGGCATTGCGGCCCTGCTCGCGCGCTTCGG
CGTCTGCGGCGGCGACAGCGCGCGCGCGGCGGGCCGCGACATCGCGAACGCCGCTAAACAGTCGTTCGGCAGCGACTAA

Upstream 100 bases:

>100_bases
CCCGTTTACTCGGTTATCCTGTCGGATCGCCCATGCGCGCAAGGACACTTTTCGTCCGATGAGTTCGTCTCGGTCACACG
CCGCCCGCGCCGCGCGGCCG

Downstream 100 bases:

>100_bases
ACGGCGCACCCCGCTGCGCCGCGCCGCGTACTCGTTTTTGCTCATACAACGAACGGTTTTCAGCGTGCACAATGAAACGT
GCGACGCACGCGTGGCCGCG

Product: diguanylate cyclase/cyclic diguanylate phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 772; Mature: 772

Protein sequence:

>772_residues
MRATRKSRRRRALFAIPLLGTLALALLWVAIIARLSVEKDSAFRDAGASAAILSTALEQHTVKAIHQVDQITRFVKYEFE
KSPTRFNLASTVEKGVVPSDTLIQVSILDARGRLVANTAEAHPKPIDLSDREHFKVHMQRNDDDLYISKPVFGRVSRHWT
LQMTRRLNHPDGSFAGVVVVSEDPAYFTNDFYNNATLGKDGVIAVISDTGAVLARSTGSTQKTPGTFSASGVYPVSERAS
GTYVDPIDGIVRIVSYRHLDGYPLGVMVGLSQAEEFADYHHTRNVYLLMTGFITLAMLAFFGVATGLIGKLLGREREMTQ
LAEFDLLTGLANRYATLRSLRNDVALPSNLSRLAILFIDLDNFKTVNDTLGHNAGDIVLQMTAARLSDAVANEGALARIG
GDEFVVVVKGENVERRAERLAEAIVRMFAEPFDVRGSSFVLHASIGIALHSVENESEIDLLKKADLAMYSAKDAGKNCYQ
FYAPHLSHRADHLMRWEQQLRVALSDGQLFLAYQPKIDLTYRCITGFEALVRWDHPEHGVISANEFISIAESTGLIVPIG
DFVIRTACEQLARWRNEGHDKLTLAVNISPVQFWRGDLIDTISRALAETGIEARRLELEITETAMMEYPELVSEKIVALK
RLGIRVALDDFGTGYSSLSYLHRFAVDTLKVDRSFIQAIPADRSVCVMVSSIVHLARSLGLTVVVEGTETEEQIAWLAAL
GRIEAQGFLFSRPVPSDGIAALLARFGVCGGDSARAAGRDIANAAKQSFGSD

Sequences:

>Translated_772_residues
MRATRKSRRRRALFAIPLLGTLALALLWVAIIARLSVEKDSAFRDAGASAAILSTALEQHTVKAIHQVDQITRFVKYEFE
KSPTRFNLASTVEKGVVPSDTLIQVSILDARGRLVANTAEAHPKPIDLSDREHFKVHMQRNDDDLYISKPVFGRVSRHWT
LQMTRRLNHPDGSFAGVVVVSEDPAYFTNDFYNNATLGKDGVIAVISDTGAVLARSTGSTQKTPGTFSASGVYPVSERAS
GTYVDPIDGIVRIVSYRHLDGYPLGVMVGLSQAEEFADYHHTRNVYLLMTGFITLAMLAFFGVATGLIGKLLGREREMTQ
LAEFDLLTGLANRYATLRSLRNDVALPSNLSRLAILFIDLDNFKTVNDTLGHNAGDIVLQMTAARLSDAVANEGALARIG
GDEFVVVVKGENVERRAERLAEAIVRMFAEPFDVRGSSFVLHASIGIALHSVENESEIDLLKKADLAMYSAKDAGKNCYQ
FYAPHLSHRADHLMRWEQQLRVALSDGQLFLAYQPKIDLTYRCITGFEALVRWDHPEHGVISANEFISIAESTGLIVPIG
DFVIRTACEQLARWRNEGHDKLTLAVNISPVQFWRGDLIDTISRALAETGIEARRLELEITETAMMEYPELVSEKIVALK
RLGIRVALDDFGTGYSSLSYLHRFAVDTLKVDRSFIQAIPADRSVCVMVSSIVHLARSLGLTVVVEGTETEEQIAWLAAL
GRIEAQGFLFSRPVPSDGIAALLARFGVCGGDSARAAGRDIANAAKQSFGSD
>Mature_772_residues
MRATRKSRRRRALFAIPLLGTLALALLWVAIIARLSVEKDSAFRDAGASAAILSTALEQHTVKAIHQVDQITRFVKYEFE
KSPTRFNLASTVEKGVVPSDTLIQVSILDARGRLVANTAEAHPKPIDLSDREHFKVHMQRNDDDLYISKPVFGRVSRHWT
LQMTRRLNHPDGSFAGVVVVSEDPAYFTNDFYNNATLGKDGVIAVISDTGAVLARSTGSTQKTPGTFSASGVYPVSERAS
GTYVDPIDGIVRIVSYRHLDGYPLGVMVGLSQAEEFADYHHTRNVYLLMTGFITLAMLAFFGVATGLIGKLLGREREMTQ
LAEFDLLTGLANRYATLRSLRNDVALPSNLSRLAILFIDLDNFKTVNDTLGHNAGDIVLQMTAARLSDAVANEGALARIG
GDEFVVVVKGENVERRAERLAEAIVRMFAEPFDVRGSSFVLHASIGIALHSVENESEIDLLKKADLAMYSAKDAGKNCYQ
FYAPHLSHRADHLMRWEQQLRVALSDGQLFLAYQPKIDLTYRCITGFEALVRWDHPEHGVISANEFISIAESTGLIVPIG
DFVIRTACEQLARWRNEGHDKLTLAVNISPVQFWRGDLIDTISRALAETGIEARRLELEITETAMMEYPELVSEKIVALK
RLGIRVALDDFGTGYSSLSYLHRFAVDTLKVDRSFIQAIPADRSVCVMVSSIVHLARSLGLTVVVEGTETEEQIAWLAAL
GRIEAQGFLFSRPVPSDGIAALLARFGVCGGDSARAAGRDIANAAKQSFGSD

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=428, Percent_Identity=36.9158878504673, Blast_Score=264, Evalue=1e-71,
Organism=Escherichia coli, GI87081921, Length=432, Percent_Identity=33.1018518518519, Blast_Score=231, Evalue=2e-61,
Organism=Escherichia coli, GI226510982, Length=385, Percent_Identity=30.3896103896104, Blast_Score=187, Evalue=3e-48,
Organism=Escherichia coli, GI1787055, Length=426, Percent_Identity=28.169014084507, Blast_Score=160, Evalue=4e-40,
Organism=Escherichia coli, GI1790496, Length=240, Percent_Identity=35.4166666666667, Blast_Score=152, Evalue=8e-38,
Organism=Escherichia coli, GI1788502, Length=252, Percent_Identity=33.7301587301587, Blast_Score=148, Evalue=2e-36,
Organism=Escherichia coli, GI1786507, Length=246, Percent_Identity=32.9268292682927, Blast_Score=136, Evalue=6e-33,
Organism=Escherichia coli, GI87081845, Length=238, Percent_Identity=32.3529411764706, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI87081743, Length=240, Percent_Identity=31.25, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI87081980, Length=252, Percent_Identity=32.1428571428571, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1788849, Length=245, Percent_Identity=32.6530612244898, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1788381, Length=396, Percent_Identity=25.2525252525253, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87082096, Length=238, Percent_Identity=29.4117647058824, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1788956, Length=165, Percent_Identity=37.5757575757576, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI87081977, Length=201, Percent_Identity=34.8258706467662, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1786584, Length=196, Percent_Identity=31.1224489795918, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI87082007, Length=232, Percent_Identity=28.8793103448276, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI145693134, Length=166, Percent_Identity=34.3373493975904, Blast_Score=77, Evalue=6e-15,
Organism=Escherichia coli, GI1787802, Length=163, Percent_Identity=31.2883435582822, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI87081881, Length=171, Percent_Identity=36.8421052631579, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787816, Length=169, Percent_Identity=32.5443786982249, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787262, Length=191, Percent_Identity=25.6544502617801, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1787410, Length=223, Percent_Identity=25.1121076233184, Blast_Score=66, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 84895; Mature: 84895

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRATRKSRRRRALFAIPLLGTLALALLWVAIIARLSVEKDSAFRDAGASAAILSTALEQH
CCCCHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHH
TVKAIHQVDQITRFVKYEFEKSPTRFNLASTVEKGVVPSDTLIQVSILDARGRLVANTAE
HHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCCCCCCEEEEEEECCCCCEEEECCC
AHPKPIDLSDREHFKVHMQRNDDDLYISKPVFGRVSRHWTLQMTRRLNHPDGSFAGVVVV
CCCCCCCCCCCCEEEEEEECCCCCEEEECCHHHCCCCCEEEEEHHHCCCCCCCEEEEEEE
SEDPAYFTNDFYNNATLGKDGVIAVISDTGAVLARSTGSTQKTPGTFSASGVYPVSERAS
CCCCCHHHCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCC
GTYVDPIDGIVRIVSYRHLDGYPLGVMVGLSQAEEFADYHHTRNVYLLMTGFITLAMLAF
CCCCCHHHHHHHHHHHHCCCCCCHHHEEEHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHH
FGVATGLIGKLLGREREMTQLAEFDLLTGLANRYATLRSLRNDVALPSNLSRLAILFIDL
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEC
DNFKTVNDTLGHNAGDIVLQMTAARLSDAVANEGALARIGGDEFVVVVKGENVERRAERL
CCCCCHHHHHCCCCCCEEEEEHHHHHHHHHCCCCCEEEECCCEEEEEEECCCHHHHHHHH
AEAIVRMFAEPFDVRGSSFVLHASIGIALHSVENESEIDLLKKADLAMYSAKDAGKNCYQ
HHHHHHHHCCCCCCCCCCEEEEEEECEEEEECCCCCHHHHHHHHHHHHEECCCCCCHHHH
FYAPHLSHRADHLMRWEQQLRVALSDGQLFLAYQPKIDLTYRCITGFEALVRWDHPEHGV
HHCHHHHHHHHHHHHHHHHHHEEECCCEEEEEECCCCCEEEHHHHHHHHHHCCCCCCCCE
ISANEFISIAESTGLIVPIGDFVIRTACEQLARWRNEGHDKLTLAVNISPVQFWRGDLID
EEHHHHHEECCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHH
TISRALAETGIEARRLELEITETAMMEYPELVSEKIVALKRLGIRVALDDFGTGYSSLSY
HHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHH
LHRFAVDTLKVDRSFIQAIPADRSVCVMVSSIVHLARSLGLTVVVEGTETEEQIAWLAAL
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHH
GRIEAQGFLFSRPVPSDGIAALLARFGVCGGDSARAAGRDIANAAKQSFGSD
HHHCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRATRKSRRRRALFAIPLLGTLALALLWVAIIARLSVEKDSAFRDAGASAAILSTALEQH
CCCCHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHH
TVKAIHQVDQITRFVKYEFEKSPTRFNLASTVEKGVVPSDTLIQVSILDARGRLVANTAE
HHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCCCCCCEEEEEEECCCCCEEEECCC
AHPKPIDLSDREHFKVHMQRNDDDLYISKPVFGRVSRHWTLQMTRRLNHPDGSFAGVVVV
CCCCCCCCCCCCEEEEEEECCCCCEEEECCHHHCCCCCEEEEEHHHCCCCCCCEEEEEEE
SEDPAYFTNDFYNNATLGKDGVIAVISDTGAVLARSTGSTQKTPGTFSASGVYPVSERAS
CCCCCHHHCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCC
GTYVDPIDGIVRIVSYRHLDGYPLGVMVGLSQAEEFADYHHTRNVYLLMTGFITLAMLAF
CCCCCHHHHHHHHHHHHCCCCCCHHHEEEHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHH
FGVATGLIGKLLGREREMTQLAEFDLLTGLANRYATLRSLRNDVALPSNLSRLAILFIDL
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEC
DNFKTVNDTLGHNAGDIVLQMTAARLSDAVANEGALARIGGDEFVVVVKGENVERRAERL
CCCCCHHHHHCCCCCCEEEEEHHHHHHHHHCCCCCEEEECCCEEEEEEECCCHHHHHHHH
AEAIVRMFAEPFDVRGSSFVLHASIGIALHSVENESEIDLLKKADLAMYSAKDAGKNCYQ
HHHHHHHHCCCCCCCCCCEEEEEEECEEEEECCCCCHHHHHHHHHHHHEECCCCCCHHHH
FYAPHLSHRADHLMRWEQQLRVALSDGQLFLAYQPKIDLTYRCITGFEALVRWDHPEHGV
HHCHHHHHHHHHHHHHHHHHHEEECCCEEEEEECCCCCEEEHHHHHHHHHHCCCCCCCCE
ISANEFISIAESTGLIVPIGDFVIRTACEQLARWRNEGHDKLTLAVNISPVQFWRGDLID
EEHHHHHEECCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHH
TISRALAETGIEARRLELEITETAMMEYPELVSEKIVALKRLGIRVALDDFGTGYSSLSY
HHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHH
LHRFAVDTLKVDRSFIQAIPADRSVCVMVSSIVHLARSLGLTVVVEGTETEEQIAWLAAL
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHH
GRIEAQGFLFSRPVPSDGIAALLARFGVCGGDSARAAGRDIANAAKQSFGSD
HHHCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]