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The map label for this gene is bah [H]

Identifier: 126452468

GI number: 126452468

Start: 640880

End: 641845

Strand: Direct

Name: bah [H]

Synonym: BURPS1106A_0668

Alternate gene names: 126452468

Gene position: 640880-641845 (Clockwise)

Preceding gene: 126454099

Following gene: 126454616

Centisome position: 16.07

GC content: 74.02

Gene sequence:

>966_bases
ATGAGTTGGCAGAGCAAGGTGGCGTGCTGGCTGCTGCGCCGGCAGTTTCGTCCGGAGACGCTGCGCCCCGTGATCGATCC
GGCGCGCGCGCGGCGGCTCACGAAGCTGCGGGTGCGCGTGCCGCGCCGTGCGCCCGCCGGCTGGCGGTTGCGCGAGCGCT
ACGGCCCGGCGGCCGCGCCGCTGCGCGGCGAGTGGCTCGAACGCGCGGACGTCGCGCCTGGGCGCGCGCAGCGCGGCCGG
ATGCTGCTGTATTTCCACGGCGGCGGCTATTACTTCTGTTCGCCGCAGACGCACCGCCCGCTCGTGTTCGCGCTGACGAA
GCTCGCCGGCGTGCGCTCGTTCTCGCTCGACTATCGGCTCGCGCCCGAGCATCCGTTTCCGGCCGCGCTCGACGATGCGC
TCGCCGCGTACCGGCAGCTCGTGTCCGCCGGCACGCCGCCGGAGTCGATCGTGTTCGGCGGCGATTCGGCGGGCGGCGGC
CTCGCGCTCGCGACGCTCGTCGCGCTGCGCGACGCGGGCGATCCGCTGCCGTCGGGCGCGGTGCTGTTCTCGCCGTGGAC
CGATCTCGCCGCGACGGGCGATACGCTGCGCACGCACGACGGGCTCGATCCGATGTTCGCGGGCGCGGCGCTCGGCCGCG
CGGCGCGCCTTTATCTCGGCGACACGCCGGGCACGCATCCGCATGCGTCGCCGCTCTACGCGGATTTCGCGGGATTGCCG
CCGCTCTTCATCCAGGCGGGCAGCACCGAGGTGCTGCTCGACGATTCGCGGCGCGTCGCCGAGAAGGCGCGCGCGGCGGG
CGTGCACGTCGAGCTGGAGATATGGCCGCAGATGCCGCACGTCTGGCAGATCTTTGTGCCGTTCGTGCCCGAATCGGCGC
GTGCGCTCGAGCGCGCGGCCGCGTTCGTGCGGCGCACCGCGGTCGAGCGCGCGACTCAGCGCACGGCCGACGCGTCGATC
GCCTGA

Upstream 100 bases:

>100_bases
GCGAACTGAGCCGCGCGGCCGGATTTAGAGGAGCCGGTCGACGGGCGCGCGCCGCAACGCACGTAGTATCGTCACATTGT
TCCGGTTCGGAGTGCACTCG

Downstream 100 bases:

>100_bases
TACGCGGCCTTCACGGCCGGCTGCCCGTACTTGCGCTCGAGCCGGCGCACCGCGAAGTGGCCGTGCGCGGCCTGCTGGAA
ATGATCGATGAAGAGCGTGT

Product: putative acetyl-hydrolase

Products: alcohol; a carboxylate [C]

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MSWQSKVACWLLRRQFRPETLRPVIDPARARRLTKLRVRVPRRAPAGWRLRERYGPAAAPLRGEWLERADVAPGRAQRGR
MLLYFHGGGYYFCSPQTHRPLVFALTKLAGVRSFSLDYRLAPEHPFPAALDDALAAYRQLVSAGTPPESIVFGGDSAGGG
LALATLVALRDAGDPLPSGAVLFSPWTDLAATGDTLRTHDGLDPMFAGAALGRAARLYLGDTPGTHPHASPLYADFAGLP
PLFIQAGSTEVLLDDSRRVAEKARAAGVHVELEIWPQMPHVWQIFVPFVPESARALERAAAFVRRTAVERATQRTADASI
A

Sequences:

>Translated_321_residues
MSWQSKVACWLLRRQFRPETLRPVIDPARARRLTKLRVRVPRRAPAGWRLRERYGPAAAPLRGEWLERADVAPGRAQRGR
MLLYFHGGGYYFCSPQTHRPLVFALTKLAGVRSFSLDYRLAPEHPFPAALDDALAAYRQLVSAGTPPESIVFGGDSAGGG
LALATLVALRDAGDPLPSGAVLFSPWTDLAATGDTLRTHDGLDPMFAGAALGRAARLYLGDTPGTHPHASPLYADFAGLP
PLFIQAGSTEVLLDDSRRVAEKARAAGVHVELEIWPQMPHVWQIFVPFVPESARALERAAAFVRRTAVERATQRTADASI
A
>Mature_320_residues
SWQSKVACWLLRRQFRPETLRPVIDPARARRLTKLRVRVPRRAPAGWRLRERYGPAAAPLRGEWLERADVAPGRAQRGRM
LLYFHGGGYYFCSPQTHRPLVFALTKLAGVRSFSLDYRLAPEHPFPAALDDALAAYRQLVSAGTPPESIVFGGDSAGGGL
ALATLVALRDAGDPLPSGAVLFSPWTDLAATGDTLRTHDGLDPMFAGAALGRAARLYLGDTPGTHPHASPLYADFAGLPP
LFIQAGSTEVLLDDSRRVAEKARAAGVHVELEIWPQMPHVWQIFVPFVPESARALERAAAFVRRTAVERATQRTADASIA

Specific function: This protein removes the N-acetyl group from bialaphos as one of the final steps of the bialaphos biosynthetic pathway [H]

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDXG' lipolytic enzyme family [H]

Homologues:

Organism=Homo sapiens, GI21328446, Length=174, Percent_Identity=32.183908045977, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1786682, Length=322, Percent_Identity=26.3975155279503, Blast_Score=75, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17567059, Length=268, Percent_Identity=25, Blast_Score=78, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013094
- InterPro:   IPR002168 [H]

Pfam domain/function: PF07859 Abhydrolase_3 [H]

EC number: 3.1.1.- [C]

Molecular weight: Translated: 35040; Mature: 34908

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: PS01173 LIPASE_GDXG_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWQSKVACWLLRRQFRPETLRPVIDPARARRLTKLRVRVPRRAPAGWRLRERYGPAAAP
CCCHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHEECCCCCCCCCCHHHHCCCCCCC
LRGEWLERADVAPGRAQRGRMLLYFHGGGYYFCSPQTHRPLVFALTKLAGVRSFSLDYRL
CCHHHHHHHCCCCCCCCCCCEEEEEECCEEEEECCCCCCHHHHHHHHHHCCEEECCCEEE
APEHPFPAALDDALAAYRQLVSAGTPPESIVFGGDSAGGGLALATLVALRDAGDPLPSGA
CCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCC
VLFSPWTDLAATGDTLRTHDGLDPMFAGAALGRAARLYLGDTPGTHPHASPLYADFAGLP
EEECCCHHHHCCCCCHHCCCCCCHHHHHHHHHHEEEEEECCCCCCCCCCCCCHHHHCCCC
PLFIQAGSTEVLLDDSRRVAEKARAAGVHVELEIWPQMPHVWQIFVPFVPESARALERAA
CEEEECCCCEEEECCHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCCHHHHHHHHH
AFVRRTAVERATQRTADASIA
HHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SWQSKVACWLLRRQFRPETLRPVIDPARARRLTKLRVRVPRRAPAGWRLRERYGPAAAP
CCHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHEECCCCCCCCCCHHHHCCCCCCC
LRGEWLERADVAPGRAQRGRMLLYFHGGGYYFCSPQTHRPLVFALTKLAGVRSFSLDYRL
CCHHHHHHHCCCCCCCCCCCEEEEEECCEEEEECCCCCCHHHHHHHHHHCCEEECCCEEE
APEHPFPAALDDALAAYRQLVSAGTPPESIVFGGDSAGGGLALATLVALRDAGDPLPSGA
CCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCC
VLFSPWTDLAATGDTLRTHDGLDPMFAGAALGRAARLYLGDTPGTHPHASPLYADFAGLP
EEECCCHHHHCCCCCHHCCCCCCHHHHHHHHHHEEEEEECCCCCCCCCCCCCHHHHCCCC
PLFIQAGSTEVLLDDSRRVAEKARAAGVHVELEIWPQMPHVWQIFVPFVPESARALERAA
CEEEECCCCEEEECCHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCCHHHHHHHHH
AFVRRTAVERATQRTADASIA
HHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Carboxylic ester; H2O [C]

Specific reaction: Carboxylic ester + H2O = an alcohol + carboxylate [C]

General reaction: Hydrolase; Acting on ester bonds; Carboxylic ester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2066341 [H]