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The map label for this gene is cusB [H]

Identifier: 126452324

GI number: 126452324

Start: 304420

End: 305991

Strand: Direct

Name: cusB [H]

Synonym: BURPS1106A_0331

Alternate gene names: 126452324

Gene position: 304420-305991 (Clockwise)

Preceding gene: 126455001

Following gene: 126452286

Centisome position: 7.63

GC content: 70.8

Gene sequence:

>1572_bases
ATGAACCATATTCGCTTGACCCGCGCGGCGCTGGCCGTGCTTGCCGCCGTCGCGCTGTCCGCGGCCGGCTACTTCGCCGG
CGCTCGCTTCGGCGCGCATGTCGACGTCGCGCATCGCGCGCACGCCACGAACACCACGAACGCCGTCGACGGAGCCGATG
CGAAGCCGGGCAGAAAAGTGCTGTACTGGCGCGATCCGATGGTGCCGAACCAGCATTTCGACAAGCCCGGCCCGTCGCCG
TTCATGGACATGCCCCTCGAACCCGTCTATGCGGACGACGGCGGCGGCGCGCCGGGCGTGCGCATCGATCCCGGCCTGCA
ACAGAACCTCGGCATCCGCTATGCGAAGGTGCGGCGGCGTGACGTCGACGAAGGCTTCGACGCGGTCGGCACGACGCAAT
TCGACGAGTCGCGCACGGCCGTCGTGCAATCGCGCGTGACCGGTTATGTCGACCGGTTGTACGCGAGCGCGCCGTTGCAG
CGCATCGCGAAGGGCGCGCCGATCGCCTCGCTGTTCGTGCCCGACTGGCTCGCGCCGCAGGAGGAATATCTCGCGCTCAA
GCGCGGCGCGATGGACGAGGCGCTGCTTGCCGCTTCGCGTGCGCGGATGCGCGCGCTATCGATTCCCGATAGCGTGATCG
CGAATCTCGACCGGACAGGCCGCGCGCAGACGCATATCGTGCTCGCCTCGCCGGAGACGGGCGTCGTCAGCGAGCTGAAC
GTGCGCGACGGCGCGATGGTGACGCCCGGGCAGACGCTCGCGAAGATCGCGGGGCTGTCGACGCTGTGGGCCGTCATCGA
CGTGCCGGAGGCGCTCGCGTCCGGCGTGCGTCCCGGCATGCGCGTCGACGCGACATTCGAGGGCGACCCGCAGCGGCGCG
TGAGCGGCGCGATTCGCGAGATCCTGCCGGGCGTGAACGCGACGACGCGCACGCTGCAGGCGCGGCTCGAGCTCGACAAT
CGCGCGCTCGCGCTCACGCCGGGCATGCTGATGCGCGCGCGCGTCGGCGCATCGCATGCGGCGTCGCGGCTCGTCGTGCC
GTCCGATGCGGTGATCGCGACGGGCAAGCGCTCGGTCGTGATCGTCAGGACGGCGGACGATCGGTTGCGGCCGGCGGACG
TGACGGTCGGCCGCGATGCCGGAGACGAAACCGAGGTGCTGGCCGGGCTCGAAGAAGGCGAAACGGTCGTCGCGTCCGGC
CAGTTCCTGATCGATTCCGAGGCGAGCCTGAAATCGGTGCTGCCGCGCCTCGAAGCCGACGCATCCGGCGCGCTCGCCGC
GCGTGCGACGCGGCCGCCGGCGCGATCATCGCCGCCGGCTGCGCAGGCGGGCGGTGCCGCGCCGGTCTACGAAACCACCG
GCAAGGTGGAGAAGATCACCGCGGCCGACATCACGTTCTCGCATCAGCCGGTGCCGGCGCTCGGCTGGGGCGCGATGACG
ATGTCGTTCGACAAGCCCGCGCCCGCCGCGTTCGCGAACGTGAAGGCGGGTGACACGGTGCGCTTCGCGTTCGAGGCGAG
CGGCGACGGCTATCGGCTGACGAAGGTCGAACCGGTCGGAGGCGCCCGATGA

Upstream 100 bases:

>100_bases
GTGCTCGATCTCGAACGCGACGTCGCGCGAGCGTGGGCGCAGCTCGACTATCAGATCGTCCCGTCGGCGATGCTCGCCGC
CGCACAGTGAAGGAGCGGAC

Downstream 100 bases:

>100_bases
TCGCGCACGTCATTCGATGGTCGATTCGCAATCGCCTGCTCGTGCTGCTCGCGACCGCGCTCGTCGCCGCATGGGGCGTG
GTGTCGCTGAACCGCACGCC

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 523; Mature: 523

Protein sequence:

>523_residues
MNHIRLTRAALAVLAAVALSAAGYFAGARFGAHVDVAHRAHATNTTNAVDGADAKPGRKVLYWRDPMVPNQHFDKPGPSP
FMDMPLEPVYADDGGGAPGVRIDPGLQQNLGIRYAKVRRRDVDEGFDAVGTTQFDESRTAVVQSRVTGYVDRLYASAPLQ
RIAKGAPIASLFVPDWLAPQEEYLALKRGAMDEALLAASRARMRALSIPDSVIANLDRTGRAQTHIVLASPETGVVSELN
VRDGAMVTPGQTLAKIAGLSTLWAVIDVPEALASGVRPGMRVDATFEGDPQRRVSGAIREILPGVNATTRTLQARLELDN
RALALTPGMLMRARVGASHAASRLVVPSDAVIATGKRSVVIVRTADDRLRPADVTVGRDAGDETEVLAGLEEGETVVASG
QFLIDSEASLKSVLPRLEADASGALAARATRPPARSSPPAAQAGGAAPVYETTGKVEKITAADITFSHQPVPALGWGAMT
MSFDKPAPAAFANVKAGDTVRFAFEASGDGYRLTKVEPVGGAR

Sequences:

>Translated_523_residues
MNHIRLTRAALAVLAAVALSAAGYFAGARFGAHVDVAHRAHATNTTNAVDGADAKPGRKVLYWRDPMVPNQHFDKPGPSP
FMDMPLEPVYADDGGGAPGVRIDPGLQQNLGIRYAKVRRRDVDEGFDAVGTTQFDESRTAVVQSRVTGYVDRLYASAPLQ
RIAKGAPIASLFVPDWLAPQEEYLALKRGAMDEALLAASRARMRALSIPDSVIANLDRTGRAQTHIVLASPETGVVSELN
VRDGAMVTPGQTLAKIAGLSTLWAVIDVPEALASGVRPGMRVDATFEGDPQRRVSGAIREILPGVNATTRTLQARLELDN
RALALTPGMLMRARVGASHAASRLVVPSDAVIATGKRSVVIVRTADDRLRPADVTVGRDAGDETEVLAGLEEGETVVASG
QFLIDSEASLKSVLPRLEADASGALAARATRPPARSSPPAAQAGGAAPVYETTGKVEKITAADITFSHQPVPALGWGAMT
MSFDKPAPAAFANVKAGDTVRFAFEASGDGYRLTKVEPVGGAR
>Mature_523_residues
MNHIRLTRAALAVLAAVALSAAGYFAGARFGAHVDVAHRAHATNTTNAVDGADAKPGRKVLYWRDPMVPNQHFDKPGPSP
FMDMPLEPVYADDGGGAPGVRIDPGLQQNLGIRYAKVRRRDVDEGFDAVGTTQFDESRTAVVQSRVTGYVDRLYASAPLQ
RIAKGAPIASLFVPDWLAPQEEYLALKRGAMDEALLAASRARMRALSIPDSVIANLDRTGRAQTHIVLASPETGVVSELN
VRDGAMVTPGQTLAKIAGLSTLWAVIDVPEALASGVRPGMRVDATFEGDPQRRVSGAIREILPGVNATTRTLQARLELDN
RALALTPGMLMRARVGASHAASRLVVPSDAVIATGKRSVVIVRTADDRLRPADVTVGRDAGDETEVLAGLEEGETVVASG
QFLIDSEASLKSVLPRLEADASGALAARATRPPARSSPPAAQAGGAAPVYETTGKVEKITAADITFSHQPVPALGWGAMT
MSFDKPAPAAFANVKAGDTVRFAFEASGDGYRLTKVEPVGGAR

Specific function: Part of a cation efflux system that mediates resistance to copper and silver [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=365, Percent_Identity=37.8082191780822, Blast_Score=249, Evalue=3e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 55063; Mature: 55063

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHIRLTRAALAVLAAVALSAAGYFAGARFGAHVDVAHRAHATNTTNAVDGADAKPGRKV
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHCCCCCCCCCCCCCCCCCCEE
LYWRDPMVPNQHFDKPGPSPFMDMPLEPVYADDGGGAPGVRIDPGLQQNLGIRYAKVRRR
EEECCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCEECCCCCCCCCCEEHHHHHH
DVDEGFDAVGTTQFDESRTAVVQSRVTGYVDRLYASAPLQRIAKGAPIASLFVPDWLAPQ
CHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCH
EEYLALKRGAMDEALLAASRARMRALSIPDSVIANLDRTGRAQTHIVLASPETGVVSELN
HHHHHHHHCCHHHHHHHHHHHHHHEECCCHHHHHCCCCCCCCEEEEEEECCCCCCEEECC
VRDGAMVTPGQTLAKIAGLSTLWAVIDVPEALASGVRPGMRVDATFEGDPQRRVSGAIRE
CCCCCEECCCHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHH
ILPGVNATTRTLQARLELDNRALALTPGMLMRARVGASHAASRLVVPSDAVIATGKRSVV
HHCCCCHHHHHHHEEEEECCCEEEECCCHHHHHHCCCHHHHCEEECCCCCEEECCCCEEE
IVRTADDRLRPADVTVGRDAGDETEVLAGLEEGETVVASGQFLIDSEASLKSVLPRLEAD
EEECCCCCCCCCCEEECCCCCCHHHHHHCCCCCCEEEECCCEEEECCHHHHHHHHHHCCC
ASGALAARATRPPARSSPPAAQAGGAAPVYETTGKVEKITAADITFSHQPVPALGWGAMT
CCCCEEECCCCCCCCCCCCCHHCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCEEE
MSFDKPAPAAFANVKAGDTVRFAFEASGDGYRLTKVEPVGGAR
EECCCCCCCCEEECCCCCEEEEEEEECCCCEEEEEECCCCCCC
>Mature Secondary Structure
MNHIRLTRAALAVLAAVALSAAGYFAGARFGAHVDVAHRAHATNTTNAVDGADAKPGRKV
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHCCCCCCCCCCCCCCCCCCEE
LYWRDPMVPNQHFDKPGPSPFMDMPLEPVYADDGGGAPGVRIDPGLQQNLGIRYAKVRRR
EEECCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCEECCCCCCCCCCEEHHHHHH
DVDEGFDAVGTTQFDESRTAVVQSRVTGYVDRLYASAPLQRIAKGAPIASLFVPDWLAPQ
CHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCH
EEYLALKRGAMDEALLAASRARMRALSIPDSVIANLDRTGRAQTHIVLASPETGVVSELN
HHHHHHHHCCHHHHHHHHHHHHHHEECCCHHHHHCCCCCCCCEEEEEEECCCCCCEEECC
VRDGAMVTPGQTLAKIAGLSTLWAVIDVPEALASGVRPGMRVDATFEGDPQRRVSGAIRE
CCCCCEECCCHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHH
ILPGVNATTRTLQARLELDNRALALTPGMLMRARVGASHAASRLVVPSDAVIATGKRSVV
HHCCCCHHHHHHHEEEEECCCEEEECCCHHHHHHCCCHHHHCEEECCCCCEEECCCCEEE
IVRTADDRLRPADVTVGRDAGDETEVLAGLEEGETVVASGQFLIDSEASLKSVLPRLEAD
EEECCCCCCCCCCEEECCCCCCHHHHHHCCCCCCEEEECCCEEEECCHHHHHHHHHHCCC
ASGALAARATRPPARSSPPAAQAGGAAPVYETTGKVEKITAADITFSHQPVPALGWGAMT
CCCCEEECCCCCCCCCCCCCHHCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCEEE
MSFDKPAPAAFANVKAGDTVRFAFEASGDGYRLTKVEPVGGAR
EECCCCCCCCEEECCCCCEEEEEEEECCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]