Click here to switch to the map view.

The map label for this gene is ephD [H]

Identifier: 126452097

GI number: 126452097

Start: 1118477

End: 1119403

Strand: Reverse

Name: ephD [H]

Synonym: BURPS1106A_1140

Alternate gene names: 126452097

Gene position: 1119403-1118477 (Counterclockwise)

Preceding gene: 126452959

Following gene: 126455029

Centisome position: 28.07

GC content: 64.94

Gene sequence:

>927_bases
ATGCACACGCCCGACCTCTTCGTTCAATCGAGCAACGTCCGCCTGGCGGTCTATACGTGGGGCGACAAGCCCAGTGCGGA
CAAGCCTCGCGACATCGTCGTGCTGGCGCATGGCTTTCCCGATCGCGCACTGTTCTGGGAGCAGGTCGCCGCCGCGTTGC
AACGCGATTTCTACGTCGTCGCCTACGACATGCGAGGCTGCGCCAATTCCACGCATATCAAGGGGGCCCGGCATTATCGG
TTCGCCTTGCTTCTCGCCGATCTCTACGCCGTCATCGACGCGGTTTCGGCAGGCCGGCCCGTGCACCTCGTCGGGCATGA
TTGGGGAGGCGTCTACGGCTGGGACGCGATCGCCGATCCGGAAGGCGCGCGCCGCATCGCATCGCTCACCACGCTTTCGC
CGAGCCTGGATCAGATCGGCTTCTATCTGCGCCGCCGGTTGCTGCGCCCGACGCCGCGCCACCTCGCGCAGTTGGTCGGC
CAACTGATGCGCAACAGCCTGATGACCTTCTTCACGGCGCCATTGCTGCCGGAGCTGCTGTTCACCAGCGGACTCGCCAT
GGCGATGTTCCGTCGAATCATCGCGCACTACGAGCCGCGCATCACGTTCCGGAAAAACGACGGCATGGAAGGCGACGCGA
TACGCTACCTCGGCATTTATCGGGCGAACCTGCTGCAACGCGTACTGCGCCCGAGGAAGCGCGTCAGTACGACGCCGGTA
CATGCGCTGATGGCGATTCACGATCCTTTCCTGCCTCCGGCGCTCTTCGAAGGCTGCCGCGAATTCACGACGCGATACAG
CGAATCGACCGTCGACGCCGCGCACTGGGCGCCCTTGAGCCGGCCGCAGGAAATCGCGGAAACGGTTGGCGCGTTCGTGC
GGCAAGCCAGCCGGCGCCCCGACGTCGCGCTGCAATCGGCAAGCTGA

Upstream 100 bases:

>100_bases
CGGTCGGCTTCAGCAGCAGCCTGCTTTTTCTGGCCGCTTTCCATGTGATCTTCGGCCAGGCAACCCGAGAGCACAACTAA
CCACTTCGGAGCGACCCGAC

Downstream 100 bases:

>100_bases
GAAGGAAGCGCTCGCGCGGCGACACGTGGCGTGCTGCGCGAGCAGACGCAGGCACGCGACGCGACGCGCGTCGCTCGTTC
GATTCGCCTCGCGTAGCCGT

Product: alpha/beta fold family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MHTPDLFVQSSNVRLAVYTWGDKPSADKPRDIVVLAHGFPDRALFWEQVAAALQRDFYVVAYDMRGCANSTHIKGARHYR
FALLLADLYAVIDAVSAGRPVHLVGHDWGGVYGWDAIADPEGARRIASLTTLSPSLDQIGFYLRRRLLRPTPRHLAQLVG
QLMRNSLMTFFTAPLLPELLFTSGLAMAMFRRIIAHYEPRITFRKNDGMEGDAIRYLGIYRANLLQRVLRPRKRVSTTPV
HALMAIHDPFLPPALFEGCREFTTRYSESTVDAAHWAPLSRPQEIAETVGAFVRQASRRPDVALQSAS

Sequences:

>Translated_308_residues
MHTPDLFVQSSNVRLAVYTWGDKPSADKPRDIVVLAHGFPDRALFWEQVAAALQRDFYVVAYDMRGCANSTHIKGARHYR
FALLLADLYAVIDAVSAGRPVHLVGHDWGGVYGWDAIADPEGARRIASLTTLSPSLDQIGFYLRRRLLRPTPRHLAQLVG
QLMRNSLMTFFTAPLLPELLFTSGLAMAMFRRIIAHYEPRITFRKNDGMEGDAIRYLGIYRANLLQRVLRPRKRVSTTPV
HALMAIHDPFLPPALFEGCREFTTRYSESTVDAAHWAPLSRPQEIAETVGAFVRQASRRPDVALQSAS
>Mature_308_residues
MHTPDLFVQSSNVRLAVYTWGDKPSADKPRDIVVLAHGFPDRALFWEQVAAALQRDFYVVAYDMRGCANSTHIKGARHYR
FALLLADLYAVIDAVSAGRPVHLVGHDWGGVYGWDAIADPEGARRIASLTTLSPSLDQIGFYLRRRLLRPTPRHLAQLVG
QLMRNSLMTFFTAPLLPELLFTSGLAMAMFRRIIAHYEPRITFRKNDGMEGDAIRYLGIYRANLLQRVLRPRKRVSTTPV
HALMAIHDPFLPPALFEGCREFTTRYSESTVDAAHWAPLSRPQEIAETVGAFVRQASRRPDVALQSAS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI218777837, Length=296, Percent_Identity=22.2972972972973, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI218777840, Length=302, Percent_Identity=26.158940397351, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI13376164, Length=302, Percent_Identity=26.158940397351, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00106 adh_short [H]

EC number: NA

Molecular weight: Translated: 34667; Mature: 34667

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTPDLFVQSSNVRLAVYTWGDKPSADKPRDIVVLAHGFPDRALFWEQVAAALQRDFYVV
CCCCCCEEECCCCEEEEEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCEEE
AYDMRGCANSTHIKGARHYRFALLLADLYAVIDAVSAGRPVHLVGHDWGGVYGWDAIADP
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCC
EGARRIASLTTLSPSLDQIGFYLRRRLLRPTPRHLAQLVGQLMRNSLMTFFTAPLLPELL
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTSGLAMAMFRRIIAHYEPRITFRKNDGMEGDAIRYLGIYRANLLQRVLRPRKRVSTTPV
HHCCHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHH
HALMAIHDPFLPPALFEGCREFTTRYSESTVDAAHWAPLSRPQEIAETVGAFVRQASRRP
HHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCC
DVALQSAS
CCEECCCC
>Mature Secondary Structure
MHTPDLFVQSSNVRLAVYTWGDKPSADKPRDIVVLAHGFPDRALFWEQVAAALQRDFYVV
CCCCCCEEECCCCEEEEEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCEEE
AYDMRGCANSTHIKGARHYRFALLLADLYAVIDAVSAGRPVHLVGHDWGGVYGWDAIADP
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCC
EGARRIASLTTLSPSLDQIGFYLRRRLLRPTPRHLAQLVGQLMRNSLMTFFTAPLLPELL
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTSGLAMAMFRRIIAHYEPRITFRKNDGMEGDAIRYLGIYRANLLQRVLRPRKRVSTTPV
HHCCHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHH
HALMAIHDPFLPPALFEGCREFTTRYSESTVDAAHWAPLSRPQEIAETVGAFVRQASRRP
HHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCC
DVALQSAS
CCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]