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The map label for this gene is lipB [H]

Identifier: 126452030

GI number: 126452030

Start: 426722

End: 427462

Strand: Direct

Name: lipB [H]

Synonym: BURPS1106A_0463

Alternate gene names: 126452030

Gene position: 426722-427462 (Clockwise)

Preceding gene: 126451638

Following gene: 126453169

Centisome position: 10.7

GC content: 68.83

Gene sequence:

>741_bases
GTGCCTTCCGCTCCCGCCGCGCCCGACGCCGCCGCGTCCGTTGCTCCGAATCCGCCCGCCGCATTGCCCGTCACCGTCCG
GTGGCTCGGCGAGACGCCTTACGACGCCTGCTTCGACGCGATGCGCGCGTTCACCGACGCGCGCACGCCCGACACCGACG
ACGAGATCTGGGTCGTCGAGCATCCGCCCGTCTACACGCTCGGCCAGGCCGGCAATCCGGCGCACCTGCTCGTTGCCGAC
AGCGGCGTGCCGCTCGTGAAGGTCGATCGCGGCGGGCAGATCACCTACCACGGTCCGGGGCAAATCGTCGCATATCTGCT
CGTGGACTTGAGGCGGCGCAAGCTGATGGTGCGCACGCTCGTCACGCGGATCGAAGAGGCCGTGATCGAGACGCTCGCGG
CGTATAATCTCGCGTCGGCCCGCAAGGCCGGCGCGCCCGGGATCTACGTGGAATCGGGGCCGCATCGAGGCGCGAAGATT
GCCGCGCTCGGCCTGAAGATCCGCAACGGCTGCAGCTATCACGGCCTGAGCGTCAACGTGAAGATGGATCTGCGCCCGTT
TCTCGCGATCAACCCGTGCGGCTACGCGGGGCTCGAAACGATCGACATGGCGAGCCTCGGCGCGACCGCCGACTGGCACG
AAGTCGCGCAGACGCTCGTGCGCCGCCTGATCGCCCACCTCGACGGCGCAACCGCGGCCGCCGCATTGCCGCAGCAGGCA
CTGGAACAATCGAATGACTGA

Upstream 100 bases:

>100_bases
CCGTCTGAGCGTGAGCCGGACGGCGCGCGCTGTCCGGCACCGGCGAGGTGCATGGGTTTTCGGTAAACTACCGCCCATGT
CAGCCCCGCCGGTTTCCATC

Downstream 100 bases:

>100_bases
CCTTACCGCTACCCCCGCACCCGCCGAACCGGCCGCTTCCGCCTACGATCCGACCGCCAAGCAGAAGGCGCAGGCGAAGA
CCGCGCGCATTCCGATCAAG

Product: lipoate-protein ligase B

Products: NA

Alternate protein names: Lipoate-protein ligase B; Lipoyl/octanoyl transferase; Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase [H]

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MPSAPAAPDAAASVAPNPPAALPVTVRWLGETPYDACFDAMRAFTDARTPDTDDEIWVVEHPPVYTLGQAGNPAHLLVAD
SGVPLVKVDRGGQITYHGPGQIVAYLLVDLRRRKLMVRTLVTRIEEAVIETLAAYNLASARKAGAPGIYVESGPHRGAKI
AALGLKIRNGCSYHGLSVNVKMDLRPFLAINPCGYAGLETIDMASLGATADWHEVAQTLVRRLIAHLDGATAAAALPQQA
LEQSND

Sequences:

>Translated_246_residues
MPSAPAAPDAAASVAPNPPAALPVTVRWLGETPYDACFDAMRAFTDARTPDTDDEIWVVEHPPVYTLGQAGNPAHLLVAD
SGVPLVKVDRGGQITYHGPGQIVAYLLVDLRRRKLMVRTLVTRIEEAVIETLAAYNLASARKAGAPGIYVESGPHRGAKI
AALGLKIRNGCSYHGLSVNVKMDLRPFLAINPCGYAGLETIDMASLGATADWHEVAQTLVRRLIAHLDGATAAAALPQQA
LEQSND
>Mature_245_residues
PSAPAAPDAAASVAPNPPAALPVTVRWLGETPYDACFDAMRAFTDARTPDTDDEIWVVEHPPVYTLGQAGNPAHLLVADS
GVPLVKVDRGGQITYHGPGQIVAYLLVDLRRRKLMVRTLVTRIEEAVIETLAAYNLASARKAGAPGIYVESGPHRGAKIA
ALGLKIRNGCSYHGLSVNVKMDLRPFLAINPCGYAGLETIDMASLGATADWHEVAQTLVRRLIAHLDGATAAAALPQQAL
EQSND

Specific function: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate

COG id: COG0321

COG function: function code H; Lipoate-protein ligase B

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lipB family [H]

Homologues:

Organism=Escherichia coli, GI87081767, Length=206, Percent_Identity=49.0291262135922, Blast_Score=204, Evalue=5e-54,
Organism=Saccharomyces cerevisiae, GI6323268, Length=198, Percent_Identity=28.7878787878788, Blast_Score=86, Evalue=7e-18,
Organism=Drosophila melanogaster, GI21355483, Length=158, Percent_Identity=33.5443037974684, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004143
- InterPro:   IPR000544
- InterPro:   IPR020605 [H]

Pfam domain/function: PF03099 BPL_LipA_LipB [H]

EC number: =2.3.1.181 [H]

Molecular weight: Translated: 26102; Mature: 25971

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS01313 LIPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSAPAAPDAAASVAPNPPAALPVTVRWLGETPYDACFDAMRAFTDARTPDTDDEIWVVE
CCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEE
HPPVYTLGQAGNPAHLLVADSGVPLVKVDRGGQITYHGPGQIVAYLLVDLRRRKLMVRTL
CCCEEEECCCCCCEEEEEECCCCCEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHH
VTRIEEAVIETLAAYNLASARKAGAPGIYVESGPHRGAKIAALGLKIRNGCSYHGLSVNV
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEEEECCCCCCCCEEEEE
KMDLRPFLAINPCGYAGLETIDMASLGATADWHEVAQTLVRRLIAHLDGATAAAALPQQA
EECCCCEEEECCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LEQSND
HHCCCC
>Mature Secondary Structure 
PSAPAAPDAAASVAPNPPAALPVTVRWLGETPYDACFDAMRAFTDARTPDTDDEIWVVE
CCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEE
HPPVYTLGQAGNPAHLLVADSGVPLVKVDRGGQITYHGPGQIVAYLLVDLRRRKLMVRTL
CCCEEEECCCCCCEEEEEECCCCCEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHH
VTRIEEAVIETLAAYNLASARKAGAPGIYVESGPHRGAKIAALGLKIRNGCSYHGLSVNV
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEEEECCCCCCCCEEEEE
KMDLRPFLAINPCGYAGLETIDMASLGATADWHEVAQTLVRRLIAHLDGATAAAALPQQA
EECCCCEEEECCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LEQSND
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA