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The map label for this gene is trpS [H]

Identifier: 126451704

GI number: 126451704

Start: 2582733

End: 2583935

Strand: Reverse

Name: trpS [H]

Synonym: BURPS1106A_2621

Alternate gene names: 126451704

Gene position: 2583935-2582733 (Counterclockwise)

Preceding gene: 126454528

Following gene: 126452855

Centisome position: 64.79

GC content: 65.92

Gene sequence:

>1203_bases
ATGTTCCCAGACCGTATCTTTTCCGGCATGCGACCCACGGGGTCGCTCCATCTCGGCCACTATCACGGCGTGCTGAAGAA
CTGGGTCAAGCTGCAGTCCGAGTATCCGTGCTTCTTCTGCGTCGTCGACTGGCACGCGCTGACGACGCACTACGAAACGC
CCGAGGTGATCGAGAAGAACGTCTGGGACGTGCTGATCGACTGGCTCGCATCGGGCATCGATCCGGCGCAGGCGACGCTG
TTCATCCAGAGCAAGGTGCCCGAGCATGCGGAGCTCGCGCTGTTGCTCGGGATGAGCACGCCGCTCGGCTGGCTCGAACG
TGTGCCGACCTACAAGGAGCAGATCGAGAAGCTGAAGGACAAGGATCTGTCGACGTACGGCTTCCTCGGCTATCCGGTGC
TGATGGCGGCCGACATCCTGCTGTACCGCGGCTCGCTCGTGCCGGTCGGCGAGGACCAGGTGCCGCACGTCGAGATGACG
CGCGAGATCGCGCGCCGCTTCAATTACCTGTACGGCCGCGAGCCGGGCTTCGAGGAGAAGGCGCTCGAGGCGGCGAAGAA
GCTGGGCGGCAAGCGTGCGAAGCTCTATCACGAGTTGCGCAACGCGTACCAGCAGGAGGGCGACGACGAGGCGCTCGAAC
AGGCGCGCGCGATGCTGCAGGAATCGCAGAGCCTGTCGATGAGCGACCGCGAGCGCCTGTTCGGCTATCTCGAAGGCGCG
CGCAAGATCATCCTCGTCGAGCCGCAGGCGCTGTTGACGGAGGCGTCGCGCATGCCGGGCCTCGACGGGCAGAAGATGTC
GAAGTCGTACGGCAACACGATCGGCCTGCGCGAGGACGCCGAGACGATCACGAAGAAGGTCCGCACGATGCCGACCGATC
CCGCGCGCGTGCGCCGCAGCGATCCGGGCGATCCGGACAAGTGCCCGGTCTGGCAACTGCACCAGGTCTACACGGACGAA
ACGACGCACGAGTGGGTGCAGCAGGGGTGCCGCTCGGCGGGCATCGGCTGCCTCGACTGCAAGCAGCCGGTGGTCGAAGG
CATCCTGCGCGAGCAGCAGCCGATGCTCGAGCGCGCGCAGAAGTACATGGACGATCCGTCGCTGCTGCGCGCGATCGTCG
CCGACGGCTGCGACAAGGCGCGCAAGCACGCGACGGAGACGATGCGCGACGTGCGCGAGGCGATGGGGCTGTCGTACAGT
TGA

Upstream 100 bases:

>100_bases
GCCTGCTGACGAAACTCTGGCTGCGGCCGCTGGTGGGCGCCGGCTATGCCGTCGTGACGGCCATCCTGACTCCTTTCGCC
TCGCTCTTCTAACGACAATC

Downstream 100 bases:

>100_bases
AAACGCCGGCGATCGAAATCGAGCGCGTGCCCGGGGCGGGCGCGCACGGCGCCGCGACCGAGCCGTCGGCGTGGGTGCGC
CGCTGGTCGCATCTCGTGCC

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MFPDRIFSGMRPTGSLHLGHYHGVLKNWVKLQSEYPCFFCVVDWHALTTHYETPEVIEKNVWDVLIDWLASGIDPAQATL
FIQSKVPEHAELALLLGMSTPLGWLERVPTYKEQIEKLKDKDLSTYGFLGYPVLMAADILLYRGSLVPVGEDQVPHVEMT
REIARRFNYLYGREPGFEEKALEAAKKLGGKRAKLYHELRNAYQQEGDDEALEQARAMLQESQSLSMSDRERLFGYLEGA
RKIILVEPQALLTEASRMPGLDGQKMSKSYGNTIGLREDAETITKKVRTMPTDPARVRRSDPGDPDKCPVWQLHQVYTDE
TTHEWVQQGCRSAGIGCLDCKQPVVEGILREQQPMLERAQKYMDDPSLLRAIVADGCDKARKHATETMRDVREAMGLSYS

Sequences:

>Translated_400_residues
MFPDRIFSGMRPTGSLHLGHYHGVLKNWVKLQSEYPCFFCVVDWHALTTHYETPEVIEKNVWDVLIDWLASGIDPAQATL
FIQSKVPEHAELALLLGMSTPLGWLERVPTYKEQIEKLKDKDLSTYGFLGYPVLMAADILLYRGSLVPVGEDQVPHVEMT
REIARRFNYLYGREPGFEEKALEAAKKLGGKRAKLYHELRNAYQQEGDDEALEQARAMLQESQSLSMSDRERLFGYLEGA
RKIILVEPQALLTEASRMPGLDGQKMSKSYGNTIGLREDAETITKKVRTMPTDPARVRRSDPGDPDKCPVWQLHQVYTDE
TTHEWVQQGCRSAGIGCLDCKQPVVEGILREQQPMLERAQKYMDDPSLLRAIVADGCDKARKHATETMRDVREAMGLSYS
>Mature_400_residues
MFPDRIFSGMRPTGSLHLGHYHGVLKNWVKLQSEYPCFFCVVDWHALTTHYETPEVIEKNVWDVLIDWLASGIDPAQATL
FIQSKVPEHAELALLLGMSTPLGWLERVPTYKEQIEKLKDKDLSTYGFLGYPVLMAADILLYRGSLVPVGEDQVPHVEMT
REIARRFNYLYGREPGFEEKALEAAKKLGGKRAKLYHELRNAYQQEGDDEALEQARAMLQESQSLSMSDRERLFGYLEGA
RKIILVEPQALLTEASRMPGLDGQKMSKSYGNTIGLREDAETITKKVRTMPTDPARVRRSDPGDPDKCPVWQLHQVYTDE
TTHEWVQQGCRSAGIGCLDCKQPVVEGILREQQPMLERAQKYMDDPSLLRAIVADGCDKARKHATETMRDVREAMGLSYS

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=189, Percent_Identity=41.7989417989418, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI41352700, Length=169, Percent_Identity=43.7869822485207, Blast_Score=141, Evalue=8e-34,
Organism=Escherichia coli, GI1789786, Length=167, Percent_Identity=46.7065868263473, Blast_Score=166, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI71982800, Length=176, Percent_Identity=35.7954545454545, Blast_Score=117, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI71982793, Length=176, Percent_Identity=35.7954545454545, Blast_Score=115, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6320474, Length=184, Percent_Identity=36.9565217391304, Blast_Score=121, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24666151, Length=172, Percent_Identity=42.4418604651163, Blast_Score=151, Evalue=7e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 45448; Mature: 45448

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFPDRIFSGMRPTGSLHLGHYHGVLKNWVKLQSEYPCFFCVVDWHALTTHYETPEVIEKN
CCCHHHHCCCCCCCCEECHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHCCCCCHHHHHHH
VWDVLIDWLASGIDPAQATLFIQSKVPEHAELALLLGMSTPLGWLERVPTYKEQIEKLKD
HHHHHHHHHHCCCCHHHHEEEECCCCCCHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHH
KDLSTYGFLGYPVLMAADILLYRGSLVPVGEDQVPHVEMTREIARRFNYLYGREPGFEEK
CCCCHHCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHH
ALEAAKKLGGKRAKLYHELRNAYQQEGDDEALEQARAMLQESQSLSMSDRERLFGYLEGA
HHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
RKIILVEPQALLTEASRMPGLDGQKMSKSYGNTIGLREDAETITKKVRTMPTDPARVRRS
CEEEEECCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHCCC
DPGDPDKCPVWQLHQVYTDETTHEWVQQGCRSAGIGCLDCKQPVVEGILREQQPMLERAQ
CCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KYMDDPSLLRAIVADGCDKARKHATETMRDVREAMGLSYS
HHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFPDRIFSGMRPTGSLHLGHYHGVLKNWVKLQSEYPCFFCVVDWHALTTHYETPEVIEKN
CCCHHHHCCCCCCCCEECHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHCCCCCHHHHHHH
VWDVLIDWLASGIDPAQATLFIQSKVPEHAELALLLGMSTPLGWLERVPTYKEQIEKLKD
HHHHHHHHHHCCCCHHHHEEEECCCCCCHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHH
KDLSTYGFLGYPVLMAADILLYRGSLVPVGEDQVPHVEMTREIARRFNYLYGREPGFEEK
CCCCHHCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHH
ALEAAKKLGGKRAKLYHELRNAYQQEGDDEALEQARAMLQESQSLSMSDRERLFGYLEGA
HHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
RKIILVEPQALLTEASRMPGLDGQKMSKSYGNTIGLREDAETITKKVRTMPTDPARVRRS
CEEEEECCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHCCC
DPGDPDKCPVWQLHQVYTDETTHEWVQQGCRSAGIGCLDCKQPVVEGILREQQPMLERAQ
CCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KYMDDPSLLRAIVADGCDKARKHATETMRDVREAMGLSYS
HHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]