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The map label for this gene is gpsA

Identifier: 126451689

GI number: 126451689

Start: 466168

End: 467175

Strand: Direct

Name: gpsA

Synonym: BURPS1106A_0501

Alternate gene names: 126451689

Gene position: 466168-467175 (Clockwise)

Preceding gene: 126454083

Following gene: 126454783

Centisome position: 11.69

GC content: 74.7

Gene sequence:

>1008_bases
GTGCTGAGCATGAAAGTCGCGGTTCTCGGCGCCGGCGCGTGGGGCACCGCGCTCGCGGCGCATCTGGCCGTGCGGCACGA
CACGCTGCTCTGGGCGCGCGACGCGGCGCTCGTCGCCGAGCTTGCCGCGCGGCGCGAGAACGCCCGCTATCTGGGCGGCG
TCGCGCTGCCGCCCGGGCTGCGCTACGAGGCCGATCTCGCGACGGCGCTGTCGCACGCGCAAGCGGACGACGCGCTCTGC
GTGATCGCGGCGCCCGTGGCCGGGCTGCGCGCGCTGTGCCGCGCGATGCGCGACGCACGCCGCGTGCCCGCTCACTTCGT
CTGGGTCTGCAAGGGCTTCGAGGCCGACACGCGGCGGCTGCCGCATCAGATGGTCGCCGAGGAACTGCCGGATCACGCGA
GCTACGGCGTGCTGTCGGGCCCGAGCTTCGCGCGTGAGGTCGCGCAGGGGCTGCCCGTCGCGCTGACGGTCGCGAGCGCG
TCGGCCGCGTGCCGCGAGCGTACGCTCGCGGCGTTTCATCATGGCGCGATGCGGATCTATACAGGCGACGACGTCGTCGG
CGTCGAGGTCGGCGGCGCGGTGAAGAACGTGCTCGCGATCGCGACGGGGATCGCCGACGGCCTGGGCCTCGGCCTCAATG
CGCGTGCGGCGCTCGTCACGCGCGGGCTCGCGGAGATGTCGCGCCTGGGCGTCGCGCTCGGCGGCCGCGCGGAGACGTTC
ACGGGCCTCACGGGCCTGGGTGACCTGATCCTCACGGCGACGGGCGATCTGTCGCGCAACCGGAGCGTCGGCCTGCAGCT
CGCGGCCGGCCGCTCGCTCGACGATATCCTCGCCGCGCTCGGCCACGTGGCCGAAGGCGTGCGCTGCGCGCGCGCGGTGC
TGTCGATCGCGCGCGAGCGCGGCGTCGACATGCCGATCACGGAGGCGGTGTGCGCGGTGCTGTTCGACGGCGTCGCGCCG
CGCGATGCGGTGAGCGGCCTGCTGCGGCGGGACGCGAAAGCCGAATAG

Upstream 100 bases:

>100_bases
CAGGCGCTGTACGAGCAGCGCCTCGCCGAAATCTCGCAGCAACAACAGCAAGGCGGCGCGCCGAACGGCACGACGCTGAA
CTGAGCATGAGCGAGAACCG

Downstream 100 bases:

>100_bases
GTCCGGCGAGCCGGATCGACGCCAATTCAATCCGAACCGAACGCGGGCGCGCTGCACGGCGGCGCGCCCGCGCTTGTGCT
TGCGCGCTGCATGCGCGCGC

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MLSMKVAVLGAGAWGTALAAHLAVRHDTLLWARDAALVAELAARRENARYLGGVALPPGLRYEADLATALSHAQADDALC
VIAAPVAGLRALCRAMRDARRVPAHFVWVCKGFEADTRRLPHQMVAEELPDHASYGVLSGPSFAREVAQGLPVALTVASA
SAACRERTLAAFHHGAMRIYTGDDVVGVEVGGAVKNVLAIATGIADGLGLGLNARAALVTRGLAEMSRLGVALGGRAETF
TGLTGLGDLILTATGDLSRNRSVGLQLAAGRSLDDILAALGHVAEGVRCARAVLSIARERGVDMPITEAVCAVLFDGVAP
RDAVSGLLRRDAKAE

Sequences:

>Translated_335_residues
MLSMKVAVLGAGAWGTALAAHLAVRHDTLLWARDAALVAELAARRENARYLGGVALPPGLRYEADLATALSHAQADDALC
VIAAPVAGLRALCRAMRDARRVPAHFVWVCKGFEADTRRLPHQMVAEELPDHASYGVLSGPSFAREVAQGLPVALTVASA
SAACRERTLAAFHHGAMRIYTGDDVVGVEVGGAVKNVLAIATGIADGLGLGLNARAALVTRGLAEMSRLGVALGGRAETF
TGLTGLGDLILTATGDLSRNRSVGLQLAAGRSLDDILAALGHVAEGVRCARAVLSIARERGVDMPITEAVCAVLFDGVAP
RDAVSGLLRRDAKAE
>Mature_335_residues
MLSMKVAVLGAGAWGTALAAHLAVRHDTLLWARDAALVAELAARRENARYLGGVALPPGLRYEADLATALSHAQADDALC
VIAAPVAGLRALCRAMRDARRVPAHFVWVCKGFEADTRRLPHQMVAEELPDHASYGVLSGPSFAREVAQGLPVALTVASA
SAACRERTLAAFHHGAMRIYTGDDVVGVEVGGAVKNVLAIATGIADGLGLGLNARAALVTRGLAEMSRLGVALGGRAETF
TGLTGLGDLILTATGDLSRNRSVGLQLAAGRSLDDILAALGHVAEGVRCARAVLSIARERGVDMPITEAVCAVLFDGVAP
RDAVSGLLRRDAKAE

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=341, Percent_Identity=28.7390029325513, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI24307999, Length=349, Percent_Identity=26.0744985673352, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI1790037, Length=332, Percent_Identity=44.2771084337349, Blast_Score=249, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI32564399, Length=358, Percent_Identity=26.8156424581006, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI193210136, Length=366, Percent_Identity=26.5027322404372, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI32564403, Length=366, Percent_Identity=26.5027322404372, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17507425, Length=282, Percent_Identity=27.3049645390071, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI193210134, Length=354, Percent_Identity=24.2937853107345, Blast_Score=78, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6320181, Length=352, Percent_Identity=28.125, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6324513, Length=352, Percent_Identity=27.8409090909091, Blast_Score=97, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281362270, Length=297, Percent_Identity=27.9461279461279, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI45551945, Length=297, Percent_Identity=27.9461279461279, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17136202, Length=346, Percent_Identity=25.7225433526012, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17136200, Length=345, Percent_Identity=25.7971014492754, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17136204, Length=346, Percent_Identity=25.7225433526012, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI22026922, Length=330, Percent_Identity=24.2424242424242, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24648969, Length=265, Percent_Identity=28.3018867924528, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_BURM7 (A3MQ27)

Other databases:

- EMBL:   CP000548
- RefSeq:   YP_001082363.1
- ProteinModelPortal:   A3MQ27
- GeneID:   4893711
- GenomeReviews:   CP000548_GR
- KEGG:   bmn:BMA10247_2842
- TIGR:   BMA10247_2842
- HOGENOM:   HBG586392
- OMA:   NVAKGIE
- ProtClustDB:   PRK00094
- BioCyc:   BMAL320389:BMA10247_2842-MONOMER
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 34695; Mature: 34695

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 195-195 BINDING 111-111 BINDING 111-111 BINDING 144-144 BINDING 259-259 BINDING 285-285

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSMKVAVLGAGAWGTALAAHLAVRHDTLLWARDAALVAELAARRENARYLGGVALPPGL
CCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCEECCCCC
RYEADLATALSHAQADDALCVIAAPVAGLRALCRAMRDARRVPAHFVWVCKGFEADTRRL
CCHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHC
PHQMVAEELPDHASYGVLSGPSFAREVAQGLPVALTVASASAACRERTLAAFHHGAMRIY
CHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCEEEEE
TGDDVVGVEVGGAVKNVLAIATGIADGLGLGLNARAALVTRGLAEMSRLGVALGGRAETF
ECCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
TGLTGLGDLILTATGDLSRNRSVGLQLAAGRSLDDILAALGHVAEGVRCARAVLSIARER
HCHHHHCCEEEEECCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GVDMPITEAVCAVLFDGVAPRDAVSGLLRRDAKAE
CCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLSMKVAVLGAGAWGTALAAHLAVRHDTLLWARDAALVAELAARRENARYLGGVALPPGL
CCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCEECCCCC
RYEADLATALSHAQADDALCVIAAPVAGLRALCRAMRDARRVPAHFVWVCKGFEADTRRL
CCHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHC
PHQMVAEELPDHASYGVLSGPSFAREVAQGLPVALTVASASAACRERTLAAFHHGAMRIY
CHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCEEEEE
TGDDVVGVEVGGAVKNVLAIATGIADGLGLGLNARAALVTRGLAEMSRLGVALGGRAETF
ECCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
TGLTGLGDLILTATGDLSRNRSVGLQLAAGRSLDDILAALGHVAEGVRCARAVLSIARER
HCHHHHCCEEEEECCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GVDMPITEAVCAVLFDGVAPRDAVSGLLRRDAKAE
CCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA