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The map label for this gene is cynT [H]

Identifier: 126451676

GI number: 126451676

Start: 3370761

End: 3371420

Strand: Direct

Name: cynT [H]

Synonym: BURPS1106A_3463

Alternate gene names: 126451676

Gene position: 3370761-3371420 (Clockwise)

Preceding gene: 126454042

Following gene: 126454570

Centisome position: 84.51

GC content: 70.0

Gene sequence:

>660_bases
ATGCAGGACATCATCGAAGGGTTTCTGAAGTTCCGGCGCGACGCATTCGCGCCGCGCACGGCGTTGTTCAAGCGCCTCGC
CACGAGCCAGCAGCCACGCGCCCTCTTCATCTCGTGCTCGGACAGCCGTCTCGTGCCCGAGCTCGTCACGCAGCGCGAGC
CGGGCGAGCTGTTCGTGATCCGCAACGCGGGCAACATCGTGCCTTCGTTCGGCCCCGAGCCCGGCGGCGTATCGGCGTCC
GTCGAATACGCGGTGGCGGTGCTCGAAGTGGCCGACGTCGTCGTGTGCGGGCACTCGGACTGCGGCGCGATGCGTGCGAT
CGCGTCGTGCGCGTGCCTCGATCATCTGCCCGCCGTGCGCAGCTGGCTGCGCTACGCGGACGCCGCGAAACGCGTGAACG
AAGCGCGCGAGCATGCGGGCGAGCAGGCGCGCGTCGATTCGATGGTGCGCGAAAACGTCGTCGCGCAACTCGCGAATCTC
AATACACATCCGTCGGTGCGGCTCGCGCTCGAGCAAGGGCGCCTCACGCTGCACGGCTGGGTGTACGACATCGAGACCGG
CTCGATCGACGCGCTCGACGGCGCGACGGGCCGCTTCGTCGCGCTCGCCGGGCATCCGCGGGTGCACGCGACGCCGCCGC
GCGTCCAGCGCGCGGCGTGA

Upstream 100 bases:

>100_bases
GCGTTGCCTATGCGAACAATAATAAACCGGTCTTGGACGCTATGAATCGTTTGCCTCATGCTTCGGTCACCGGCACTCGC
CATCGATCATGGAGCACACG

Downstream 100 bases:

>100_bases
CGCATGACACCACGCGCGCCGCCCCCGGCGCGGCGCGCAGCACGCCGCGCGGCCCCCTTCCCGATCCCTCACCGCAAGGA
GTCCGTATGACCCAGTCGCA

Product: carbonic anhydrases

Products: NA

Alternate protein names: Carbonate dehydratase 1 [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MQDIIEGFLKFRRDAFAPRTALFKRLATSQQPRALFISCSDSRLVPELVTQREPGELFVIRNAGNIVPSFGPEPGGVSAS
VEYAVAVLEVADVVVCGHSDCGAMRAIASCACLDHLPAVRSWLRYADAAKRVNEAREHAGEQARVDSMVRENVVAQLANL
NTHPSVRLALEQGRLTLHGWVYDIETGSIDALDGATGRFVALAGHPRVHATPPRVQRAA

Sequences:

>Translated_219_residues
MQDIIEGFLKFRRDAFAPRTALFKRLATSQQPRALFISCSDSRLVPELVTQREPGELFVIRNAGNIVPSFGPEPGGVSAS
VEYAVAVLEVADVVVCGHSDCGAMRAIASCACLDHLPAVRSWLRYADAAKRVNEAREHAGEQARVDSMVRENVVAQLANL
NTHPSVRLALEQGRLTLHGWVYDIETGSIDALDGATGRFVALAGHPRVHATPPRVQRAA
>Mature_219_residues
MQDIIEGFLKFRRDAFAPRTALFKRLATSQQPRALFISCSDSRLVPELVTQREPGELFVIRNAGNIVPSFGPEPGGVSAS
VEYAVAVLEVADVVVCGHSDCGAMRAIASCACLDHLPAVRSWLRYADAAKRVNEAREHAGEQARVDSMVRENVVAQLANL
NTHPSVRLALEQGRLTLHGWVYDIETGSIDALDGATGRFVALAGHPRVHATPPRVQRAA

Specific function: Reversible hydration of carbon dioxide. Carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (CynS) diffuses out of the cell faster than it would be hydrated to bicarbonate, so the apparent function of this enzyme is to c

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786534, Length=219, Percent_Identity=73.5159817351598, Blast_Score=338, Evalue=2e-94,
Organism=Escherichia coli, GI1786318, Length=181, Percent_Identity=36.4640883977901, Blast_Score=105, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI25147564, Length=240, Percent_Identity=31.25, Blast_Score=103, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI115532990, Length=237, Percent_Identity=26.5822784810127, Blast_Score=94, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6324292, Length=208, Percent_Identity=28.8461538461538, Blast_Score=83, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24645213, Length=240, Percent_Identity=26.6666666666667, Blast_Score=99, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 23746; Mature: 23746

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDIIEGFLKFRRDAFAPRTALFKRLATSQQPRALFISCSDSRLVPELVTQREPGELFVI
CHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHCCCCCCCEEEE
RNAGNIVPSFGPEPGGVSASVEYAVAVLEVADVVVCGHSDCGAMRAIASCACLDHLPAVR
ECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHH
SWLRYADAAKRVNEAREHAGEQARVDSMVRENVVAQLANLNTHPSVRLALEQGRLTLHGW
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEE
VYDIETGSIDALDGATGRFVALAGHPRVHATPPRVQRAA
EEEECCCCEECCCCCCCCEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQDIIEGFLKFRRDAFAPRTALFKRLATSQQPRALFISCSDSRLVPELVTQREPGELFVI
CHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHCCCCCCCEEEE
RNAGNIVPSFGPEPGGVSASVEYAVAVLEVADVVVCGHSDCGAMRAIASCACLDHLPAVR
ECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHH
SWLRYADAAKRVNEAREHAGEQARVDSMVRENVVAQLANLNTHPSVRLALEQGRLTLHGW
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEE
VYDIETGSIDALDGATGRFVALAGHPRVHATPPRVQRAA
EEEECCCCEECCCCCCCCEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]