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The map label for this gene is ubiB

Identifier: 126451540

GI number: 126451540

Start: 660806

End: 662383

Strand: Direct

Name: ubiB

Synonym: BURPS1106A_0686

Alternate gene names: 126451540

Gene position: 660806-662383 (Clockwise)

Preceding gene: 126455337

Following gene: 126453187

Centisome position: 16.57

GC content: 66.03

Gene sequence:

>1578_bases
ATGCGCATTTTCCGTTTCGTCAAAATCGTCTTCACCGTCATCCGCTTCGGCCTCGACGAGGTCATGCTGTCGCGCATCGA
GAACCCGCGTGTGAAGCTCCTGCTGCGCATCACGACGATCGGCCGGCGTTTCGCCGATCCGCCCGCGGTGCGGCTGCGGC
GCGCGCTCGAGAGCCTCGGGCCGATCTTCGTGAAGTTCGGCCAGGTGCTGTCGACGCGGCGCGATCTGCTGCCCGTCGAT
TTCGCGAACGAGCTCGCGAAGCTGCAGGACCAGGTGCCGCCGTTCGATTCGGCCGTCGCGATCGCGATCGTCGAGAAGTC
GCTCGGCGCGCGCATCGACGTGCTGTTCGACGAGTTCGAGCGCGTGCCTGTCGCGAGCGCGTCGATCGCGCAGGTGCACT
TCGCGAAGCTCAAGCAGGGCGAGCACAAGGGCAAGGCGGTCGCGGTCAAGGTGCTGCGGCCGAACATGCTGCCCGTCATC
GATTCCGATCTCGCGCTGATGCGCGACATCGCGACCTGGGCCGAGCGCCTGTGGGCCGACGGCCGGCGGCTCAAGCCGCG
CGAGGTGGTGGCCGAATTCGACAAGTACCTGCACGACGAGCTCGACCTGATGCGCGAGGCGGCGAACGGCAGCCAGCTGC
GCCGCAATTTCGCGGGGCTCGATCTGCTGCTCGTGCCGGAAATGTTCTGGGATTACTCGACGCCCGCCGTGCTCGTGATG
GAGCGGATGACGGGCGTGCCGATCAGCCAGGTCGACACGCTGCGCGCGGCGGGCGTCGACATTCCGAAGCTCGCGCGCGA
AGGCGTCGAGATCTTCTTCACGCAGGTGTTCCGCGACGGCTTCTTCCACGCGGACATGCATCCGGGCAACATCCAGGTGA
GCCTCGATCCGAAGCACTTCGGGCGCTACATCGCGCTCGACTTCGGGATCGTCGGCGCGCTGTCGGATTTCGACAAGAAC
TACCTCGCGCAGAACTTCCTCGCATTCTTCAAGCGCGACTACCATCGCGTCGCGACGCTGCACCTCGAATCCGGCTGGGT
GCCGCCCGATACGCGCGTCGAGGAGCTCGAAAGCGCGATCCGCGCGGTCTGCGAGCCGTACTTCGATCGCGCGTTGAAGG
ACATCTCGCTCGGCCAGGTGCTGATGCGGCTGTTCTCGACGTCGCGCCGCTTCAACGTCGAGATCCAGCCGCAGCTCGTG
CTTCTGCAAAAAACGATGCTCAACGTCGAGGGGCTCGGCCGTTCGCTCGATCCGGAGCTCGACCTGTGGAAGACCGCGAA
GCCGTACCTCGAGCGCTGGATGACCGAGCAGATCGGGCTGCGCGGCTGGTACGAGCGCTTCAAGGTCGAGGCGCCGCAAT
GGAGCAAGACGCTGCCGCAGCTGCCGCGCCTCGTTCATCAGGCGCTCATCTCGCACCACGAAGCGCCGCGTGCGATCAGC
GACGATCTGATCCGGCAGATTCTCGTCGAGCAGAGGCGAACCAACCGGCTGCTGCAGGCGCTCCTCGTGTTCGGGCTCGC
GGTGGGCGCGGGCGCGGTGATCGCGCGGGTGCTGATCGTGCTCGCATATGGCGGTTGA

Upstream 100 bases:

>100_bases
TACGCTCGCGCGCGTCGAAAAACGCATCGAACGACTGGAACAAAAAATCGACGTGCGCGCGGGCGGCAGCTCGCGACGCG
CGCAGTGAGGGCCGCGAGGC

Downstream 100 bases:

>100_bases
GGCGCCGCCGGCGTCGGCGGCGTTTGCGCGGCCCGGTGCCGAGGCGACCGGTATCGGCGCACGATGCGGGGCGATGCGGG
CGCGAGGTAGGTTTGAAGCG

Product: putative ubiquinone biosynthesis protein UbiB

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 525

Protein sequence:

>525_residues
MRIFRFVKIVFTVIRFGLDEVMLSRIENPRVKLLLRITTIGRRFADPPAVRLRRALESLGPIFVKFGQVLSTRRDLLPVD
FANELAKLQDQVPPFDSAVAIAIVEKSLGARIDVLFDEFERVPVASASIAQVHFAKLKQGEHKGKAVAVKVLRPNMLPVI
DSDLALMRDIATWAERLWADGRRLKPREVVAEFDKYLHDELDLMREAANGSQLRRNFAGLDLLLVPEMFWDYSTPAVLVM
ERMTGVPISQVDTLRAAGVDIPKLAREGVEIFFTQVFRDGFFHADMHPGNIQVSLDPKHFGRYIALDFGIVGALSDFDKN
YLAQNFLAFFKRDYHRVATLHLESGWVPPDTRVEELESAIRAVCEPYFDRALKDISLGQVLMRLFSTSRRFNVEIQPQLV
LLQKTMLNVEGLGRSLDPELDLWKTAKPYLERWMTEQIGLRGWYERFKVEAPQWSKTLPQLPRLVHQALISHHEAPRAIS
DDLIRQILVEQRRTNRLLQALLVFGLAVGAGAVIARVLIVLAYGG

Sequences:

>Translated_525_residues
MRIFRFVKIVFTVIRFGLDEVMLSRIENPRVKLLLRITTIGRRFADPPAVRLRRALESLGPIFVKFGQVLSTRRDLLPVD
FANELAKLQDQVPPFDSAVAIAIVEKSLGARIDVLFDEFERVPVASASIAQVHFAKLKQGEHKGKAVAVKVLRPNMLPVI
DSDLALMRDIATWAERLWADGRRLKPREVVAEFDKYLHDELDLMREAANGSQLRRNFAGLDLLLVPEMFWDYSTPAVLVM
ERMTGVPISQVDTLRAAGVDIPKLAREGVEIFFTQVFRDGFFHADMHPGNIQVSLDPKHFGRYIALDFGIVGALSDFDKN
YLAQNFLAFFKRDYHRVATLHLESGWVPPDTRVEELESAIRAVCEPYFDRALKDISLGQVLMRLFSTSRRFNVEIQPQLV
LLQKTMLNVEGLGRSLDPELDLWKTAKPYLERWMTEQIGLRGWYERFKVEAPQWSKTLPQLPRLVHQALISHHEAPRAIS
DDLIRQILVEQRRTNRLLQALLVFGLAVGAGAVIARVLIVLAYGG
>Mature_525_residues
MRIFRFVKIVFTVIRFGLDEVMLSRIENPRVKLLLRITTIGRRFADPPAVRLRRALESLGPIFVKFGQVLSTRRDLLPVD
FANELAKLQDQVPPFDSAVAIAIVEKSLGARIDVLFDEFERVPVASASIAQVHFAKLKQGEHKGKAVAVKVLRPNMLPVI
DSDLALMRDIATWAERLWADGRRLKPREVVAEFDKYLHDELDLMREAANGSQLRRNFAGLDLLLVPEMFWDYSTPAVLVM
ERMTGVPISQVDTLRAAGVDIPKLAREGVEIFFTQVFRDGFFHADMHPGNIQVSLDPKHFGRYIALDFGIVGALSDFDKN
YLAQNFLAFFKRDYHRVATLHLESGWVPPDTRVEELESAIRAVCEPYFDRALKDISLGQVLMRLFSTSRRFNVEIQPQLV
LLQKTMLNVEGLGRSLDPELDLWKTAKPYLERWMTEQIGLRGWYERFKVEAPQWSKTLPQLPRLVHQALISHHEAPRAIS
DDLIRQILVEQRRTNRLLQALLVFGLAVGAGAVIARVLIVLAYGG

Specific function: Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC1 family. UbiB subfamily

Homologues:

Organism=Homo sapiens, GI40254938, Length=262, Percent_Identity=31.2977099236641, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI41393593, Length=276, Percent_Identity=30.0724637681159, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI217035081, Length=217, Percent_Identity=31.7972350230415, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI32261307, Length=319, Percent_Identity=28.8401253918495, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI34147522, Length=211, Percent_Identity=29.8578199052133, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI2367309, Length=525, Percent_Identity=49.1428571428571, Blast_Score=491, Evalue=1e-140,
Organism=Caenorhabditis elegans, GI17559152, Length=280, Percent_Identity=30.7142857142857, Blast_Score=132, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6325148, Length=440, Percent_Identity=26.8181818181818, Blast_Score=126, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6323282, Length=245, Percent_Identity=28.1632653061224, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6321319, Length=236, Percent_Identity=26.6949152542373, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI22024280, Length=272, Percent_Identity=31.25, Blast_Score=135, Evalue=9e-32,
Organism=Drosophila melanogaster, GI24662575, Length=269, Percent_Identity=31.5985130111524, Blast_Score=119, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIB_BURM7 (A3MNU1)

Other databases:

- EMBL:   CP000548
- RefSeq:   YP_001081927.1
- ProteinModelPortal:   A3MNU1
- GeneID:   4893424
- GenomeReviews:   CP000548_GR
- KEGG:   bmn:BMA10247_2401
- TIGR:   BMA10247_2401
- HOGENOM:   HBG593509
- OMA:   LERFWAD
- ProtClustDB:   PRK04750
- BioCyc:   BMAL320389:BMA10247_2401-MONOMER
- HAMAP:   MF_00414
- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR010232
- TIGRFAMs:   TIGR01982

Pfam domain/function: PF03109 ABC1; SSF56112 Kinase_like

EC number: NA

Molecular weight: Translated: 59776; Mature: 59776

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x10272c5c)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIFRFVKIVFTVIRFGLDEVMLSRIENPRVKLLLRITTIGRRFADPPAVRLRRALESLG
CHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCEEEEEHHHHHHHCCCCHHHHHHHHHHHHC
PIFVKFGQVLSTRRDLLPVDFANELAKLQDQVPPFDSAVAIAIVEKSLGARIDVLFDEFE
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHH
RVPVASASIAQVHFAKLKQGEHKGKAVAVKVLRPNMLPVIDSDLALMRDIATWAERLWAD
CCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCC
GRRLKPREVVAEFDKYLHDELDLMREAANGSQLRRNFAGLDLLLVPEMFWDYSTPAVLVM
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHEEHHHHHHCCCCCHHHHH
ERMTGVPISQVDTLRAAGVDIPKLAREGVEIFFTQVFRDGFFHADMHPGNIQVSLDPKHF
HHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECHHHH
GRYIALDFGIVGALSDFDKNYLAQNFLAFFKRDYHRVATLHLESGWVPPDTRVEELESAI
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHH
RAVCEPYFDRALKDISLGQVLMRLFSTSRRFNVEIQPQLVLLQKTMLNVEGLGRSLDPEL
HHHHHHHHHHHHHHCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCC
DLWKTAKPYLERWMTEQIGLRGWYERFKVEAPQWSKTLPQLPRLVHQALISHHEAPRAIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHH
DDLIRQILVEQRRTNRLLQALLVFGLAVGAGAVIARVLIVLAYGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MRIFRFVKIVFTVIRFGLDEVMLSRIENPRVKLLLRITTIGRRFADPPAVRLRRALESLG
CHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCEEEEEHHHHHHHCCCCHHHHHHHHHHHHC
PIFVKFGQVLSTRRDLLPVDFANELAKLQDQVPPFDSAVAIAIVEKSLGARIDVLFDEFE
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHH
RVPVASASIAQVHFAKLKQGEHKGKAVAVKVLRPNMLPVIDSDLALMRDIATWAERLWAD
CCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCC
GRRLKPREVVAEFDKYLHDELDLMREAANGSQLRRNFAGLDLLLVPEMFWDYSTPAVLVM
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHEEHHHHHHCCCCCHHHHH
ERMTGVPISQVDTLRAAGVDIPKLAREGVEIFFTQVFRDGFFHADMHPGNIQVSLDPKHF
HHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECHHHH
GRYIALDFGIVGALSDFDKNYLAQNFLAFFKRDYHRVATLHLESGWVPPDTRVEELESAI
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHH
RAVCEPYFDRALKDISLGQVLMRLFSTSRRFNVEIQPQLVLLQKTMLNVEGLGRSLDPEL
HHHHHHHHHHHHHHCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCC
DLWKTAKPYLERWMTEQIGLRGWYERFKVEAPQWSKTLPQLPRLVHQALISHHEAPRAIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHH
DDLIRQILVEQRRTNRLLQALLVFGLAVGAGAVIARVLIVLAYGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA