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The map label for this gene is glnS [H]

Identifier: 126451537

GI number: 126451537

Start: 1607305

End: 1609014

Strand: Reverse

Name: glnS [H]

Synonym: BURPS1106A_1655

Alternate gene names: 126451537

Gene position: 1609014-1607305 (Counterclockwise)

Preceding gene: 126454246

Following gene: 126453974

Centisome position: 40.34

GC content: 64.91

Gene sequence:

>1710_bases
ATGAGCACCGAACGCAACGACGCCACCGCGCCTTCCAATTTCATCCGCAACATCATCGACGACGACAACCGCACGGGCAA
ATGGAGCGGGCGCGTCGAAACGCGCTTTCCGCCCGAGCCGAACGGCTATCTGCACATCGGTCATGCGAAGAGCATTTGCC
TGAACTTCAGCGTCGCGCGCGACTACGGCGGCGTGTGCCATCTGCGCTTCGACGATACGAATCCGGAAAAGGAAAGCGTC
GAGTACGTGAACTCGATCGTCGACGCGGTGCGCTGGCTCGGCTTCGACTGGCAGAAGGCCGGCGTCGCCCATCAATACTT
CGCGAGCGACTACTACGACAAGCTCTACGAATTCGCCGAGCTGCTGATCCAGCGCGGCTGCGCGTACGTCGACAGCCAGA
GCGCCGACGAAATGCGCACGAACCGCGGCTCGCTCACCGAGCCGGGCACGCCGTCGCCGTTCCGCGACCGCTCGCCCGAC
GAAAACCTCGCGCTGTTTCGCCGGATGAAGGCGGGCGAGTTCGCCGAAGGCGAGCACGTGCTGCGCGCGAAGATCGACAT
GAGCTCGCCGAACATGAACATGCGCGACCCGGTGATCTACCGGATCCGCTACGCGCATCACTACCGGACGGGCGACAAGT
GGTGCGTGTACCCGATGTACGACTACACGCACTGCATCTCGGATGCGCTCGAAGGCATCACGCACTCGCTGTGCACGCTC
GAATTCGAGGATCACCGCCCGCTCTACGACTGGGTGCTCAACCAGCTCGCCGACGCCGGCGTGTTCGCGCGGCCGCTGCC
GCAGCAAATCGAATTCTCGCGTCTGAACCTCACCTATGCGATCACGAGCAAGCGCAAATTGCTGCAGCTCGTGACGGAAG
GCCACGTCGACGACTGGGACGATCCGCGGATGCCGACGATCGTCGGCGTGCGCCGCCGCGGCTTCACGCCGGAGAGCATC
CAGCTGTTCTGCGAGCGGATCGGCGTGACGAAGGTCGATTCGTGGATCGACATGAGCGTGTTCGAAGGCGCGCTGCGCGA
CGATCTCGACGACAAGGCGCCGCGCACGGTCGCCGTGCTCGATCCGCTCAAGCTCGTCATCGACAACTACCCGCAAGGCC
AGAGCGAGGAATGCACGGCGCCCGTGCACCCGCACCACCCGGAGCGCGGCCAGCGCACGTTCCCGATCTCGCGCGAGCTG
TGGATCGAGCGCGAGGATTTCAGCGAGCATCCGCCGAAGGGCTATTTCCGGCTGTTCCCGGGCAACAAGGTGCGGCTGCG
CTACGGCTACGTGATCGAATGCACGGGCGCGGACAAGGACGAGCACGGCAACGTGACCGCCGTGCACTGCAACTACTATC
CGGACAGCAAGTCGGGCACCGAAGGCGCGAACAACTACAAGGTGAAGGGCAACATCCACTGGGTGAGCGCCGCGCACGCG
TGCCCCGCCGAAGTGCGGATCTACGATCGCCTGTTCAAGGAACCGCATCCGGACGCGGGCGGGCGCAACTTCCTCGAGGC
GCTGAATCCGGATTCGAAGAAGATCGTTCAGGCGTACCTCGAGCCGGGCGCGCGCGACGCGCTGCCGGAGGCGCGCTATC
AGTTCGAGCGGCACGGCTACTTCGTCGCCGATCGCGTCGATTCGAAGCCCGGCCAGCCGGTGTTCAACCGGATCGTCGGC
CTGCGCGACAGCTGGGGCAAGCCGGCCTGA

Upstream 100 bases:

>100_bases
GCAAGGGGCGCCGCTCCTCATGACGGTCGTCCGTCAGGTAGAATTGACGTATTCGGGCGGCGCGCCATGCGCCCCCTCCC
CTTTTCTTCCCCTGTTCCGC

Downstream 100 bases:

>100_bases
TAACCGCGGCGCGGGACGACCCGCGCGACGCGGCGCCGAAAGGAGAATGCCCGGTGCGAGCCGGGCATTTTCGTTTTTCG
TTTTCACGTTCGCTAGACGC

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 569; Mature: 568

Protein sequence:

>569_residues
MSTERNDATAPSNFIRNIIDDDNRTGKWSGRVETRFPPEPNGYLHIGHAKSICLNFSVARDYGGVCHLRFDDTNPEKESV
EYVNSIVDAVRWLGFDWQKAGVAHQYFASDYYDKLYEFAELLIQRGCAYVDSQSADEMRTNRGSLTEPGTPSPFRDRSPD
ENLALFRRMKAGEFAEGEHVLRAKIDMSSPNMNMRDPVIYRIRYAHHYRTGDKWCVYPMYDYTHCISDALEGITHSLCTL
EFEDHRPLYDWVLNQLADAGVFARPLPQQIEFSRLNLTYAITSKRKLLQLVTEGHVDDWDDPRMPTIVGVRRRGFTPESI
QLFCERIGVTKVDSWIDMSVFEGALRDDLDDKAPRTVAVLDPLKLVIDNYPQGQSEECTAPVHPHHPERGQRTFPISREL
WIEREDFSEHPPKGYFRLFPGNKVRLRYGYVIECTGADKDEHGNVTAVHCNYYPDSKSGTEGANNYKVKGNIHWVSAAHA
CPAEVRIYDRLFKEPHPDAGGRNFLEALNPDSKKIVQAYLEPGARDALPEARYQFERHGYFVADRVDSKPGQPVFNRIVG
LRDSWGKPA

Sequences:

>Translated_569_residues
MSTERNDATAPSNFIRNIIDDDNRTGKWSGRVETRFPPEPNGYLHIGHAKSICLNFSVARDYGGVCHLRFDDTNPEKESV
EYVNSIVDAVRWLGFDWQKAGVAHQYFASDYYDKLYEFAELLIQRGCAYVDSQSADEMRTNRGSLTEPGTPSPFRDRSPD
ENLALFRRMKAGEFAEGEHVLRAKIDMSSPNMNMRDPVIYRIRYAHHYRTGDKWCVYPMYDYTHCISDALEGITHSLCTL
EFEDHRPLYDWVLNQLADAGVFARPLPQQIEFSRLNLTYAITSKRKLLQLVTEGHVDDWDDPRMPTIVGVRRRGFTPESI
QLFCERIGVTKVDSWIDMSVFEGALRDDLDDKAPRTVAVLDPLKLVIDNYPQGQSEECTAPVHPHHPERGQRTFPISREL
WIEREDFSEHPPKGYFRLFPGNKVRLRYGYVIECTGADKDEHGNVTAVHCNYYPDSKSGTEGANNYKVKGNIHWVSAAHA
CPAEVRIYDRLFKEPHPDAGGRNFLEALNPDSKKIVQAYLEPGARDALPEARYQFERHGYFVADRVDSKPGQPVFNRIVG
LRDSWGKPA
>Mature_568_residues
STERNDATAPSNFIRNIIDDDNRTGKWSGRVETRFPPEPNGYLHIGHAKSICLNFSVARDYGGVCHLRFDDTNPEKESVE
YVNSIVDAVRWLGFDWQKAGVAHQYFASDYYDKLYEFAELLIQRGCAYVDSQSADEMRTNRGSLTEPGTPSPFRDRSPDE
NLALFRRMKAGEFAEGEHVLRAKIDMSSPNMNMRDPVIYRIRYAHHYRTGDKWCVYPMYDYTHCISDALEGITHSLCTLE
FEDHRPLYDWVLNQLADAGVFARPLPQQIEFSRLNLTYAITSKRKLLQLVTEGHVDDWDDPRMPTIVGVRRRGFTPESIQ
LFCERIGVTKVDSWIDMSVFEGALRDDLDDKAPRTVAVLDPLKLVIDNYPQGQSEECTAPVHPHHPERGQRTFPISRELW
IEREDFSEHPPKGYFRLFPGNKVRLRYGYVIECTGADKDEHGNVTAVHCNYYPDSKSGTEGANNYKVKGNIHWVSAAHAC
PAEVRIYDRLFKEPHPDAGGRNFLEALNPDSKKIVQAYLEPGARDALPEARYQFERHGYFVADRVDSKPGQPVFNRIVGL
RDSWGKPA

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=545, Percent_Identity=45.6880733944954, Blast_Score=437, Evalue=1e-122,
Organism=Homo sapiens, GI62241042, Length=533, Percent_Identity=34.3339587242026, Blast_Score=258, Evalue=8e-69,
Organism=Escherichia coli, GI1786895, Length=558, Percent_Identity=57.3476702508961, Blast_Score=651, Evalue=0.0,
Organism=Escherichia coli, GI1788743, Length=99, Percent_Identity=31.3131313131313, Blast_Score=73, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17543332, Length=544, Percent_Identity=43.1985294117647, Blast_Score=403, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17511007, Length=531, Percent_Identity=31.4500941619586, Blast_Score=228, Evalue=9e-60,
Organism=Saccharomyces cerevisiae, GI6324742, Length=578, Percent_Identity=41.6955017301038, Blast_Score=412, Evalue=1e-116,
Organism=Saccharomyces cerevisiae, GI6321192, Length=529, Percent_Identity=32.703213610586, Blast_Score=256, Evalue=8e-69,
Organism=Drosophila melanogaster, GI17864488, Length=551, Percent_Identity=42.1052631578947, Blast_Score=414, Evalue=1e-116,
Organism=Drosophila melanogaster, GI24649466, Length=425, Percent_Identity=36.7058823529412, Blast_Score=239, Evalue=3e-63,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 65177; Mature: 65045

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTERNDATAPSNFIRNIIDDDNRTGKWSGRVETRFPPEPNGYLHIGHAKSICLNFSVAR
CCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCEEEECCCCEEEEEEEEEC
DYGGVCHLRFDDTNPEKESVEYVNSIVDAVRWLGFDWQKAGVAHQYFASDYYDKLYEFAE
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHH
LLIQRGCAYVDSQSADEMRTNRGSLTEPGTPSPFRDRSPDENLALFRRMKAGEFAEGEHV
HHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEE
LRAKIDMSSPNMNMRDPVIYRIRYAHHYRTGDKWCVYPMYDYTHCISDALEGITHSLCTL
EEEEEECCCCCCCCCCCEEEEEEEHHEECCCCCEEEEECHHHHHHHHHHHHHHHHHHEEE
EFEDHRPLYDWVLNQLADAGVFARPLPQQIEFSRLNLTYAITSKRKLLQLVTEGHVDDWD
EECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHCCCCCCC
DPRMPTIVGVRRRGFTPESIQLFCERIGVTKVDSWIDMSVFEGALRDDLDDKAPRTVAVL
CCCCCCEEEHHHCCCCHHHHHHHHHHCCCCHHCHHHHHHHHHHHHHCCCCCCCCCEEEEH
DPLKLVIDNYPQGQSEECTAPVHPHHPERGQRTFPISRELWIEREDFSEHPPKGYFRLFP
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHEEECCCCCCCCCCCEEEECC
GNKVRLRYGYVIECTGADKDEHGNVTAVHCNYYPDSKSGTEGANNYKVKGNIHWVSAAHA
CCEEEEEEEEEEEECCCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEEEEEEECCCC
CPAEVRIYDRLFKEPHPDAGGRNFLEALNPDSKKIVQAYLEPGARDALPEARYQFERHGY
CCHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHCCE
FVADRVDSKPGQPVFNRIVGLRDSWGKPA
EEEECCCCCCCCHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
STERNDATAPSNFIRNIIDDDNRTGKWSGRVETRFPPEPNGYLHIGHAKSICLNFSVAR
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCEEEECCCCEEEEEEEEEC
DYGGVCHLRFDDTNPEKESVEYVNSIVDAVRWLGFDWQKAGVAHQYFASDYYDKLYEFAE
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHH
LLIQRGCAYVDSQSADEMRTNRGSLTEPGTPSPFRDRSPDENLALFRRMKAGEFAEGEHV
HHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEE
LRAKIDMSSPNMNMRDPVIYRIRYAHHYRTGDKWCVYPMYDYTHCISDALEGITHSLCTL
EEEEEECCCCCCCCCCCEEEEEEEHHEECCCCCEEEEECHHHHHHHHHHHHHHHHHHEEE
EFEDHRPLYDWVLNQLADAGVFARPLPQQIEFSRLNLTYAITSKRKLLQLVTEGHVDDWD
EECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHCCCCCCC
DPRMPTIVGVRRRGFTPESIQLFCERIGVTKVDSWIDMSVFEGALRDDLDDKAPRTVAVL
CCCCCCEEEHHHCCCCHHHHHHHHHHCCCCHHCHHHHHHHHHHHHHCCCCCCCCCEEEEH
DPLKLVIDNYPQGQSEECTAPVHPHHPERGQRTFPISRELWIEREDFSEHPPKGYFRLFP
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHEEECCCCCCCCCCCEEEECC
GNKVRLRYGYVIECTGADKDEHGNVTAVHCNYYPDSKSGTEGANNYKVKGNIHWVSAAHA
CCEEEEEEEEEEEECCCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEEEEEEECCCC
CPAEVRIYDRLFKEPHPDAGGRNFLEALNPDSKKIVQAYLEPGARDALPEARYQFERHGY
CCHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHCCE
FVADRVDSKPGQPVFNRIVGLRDSWGKPA
EEEECCCCCCCCHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA