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The map label for this gene is fhaC [H]

Identifier: 126447774

GI number: 126447774

Start: 436798

End: 438474

Strand: Direct

Name: fhaC [H]

Synonym: BMA10247_A0491

Alternate gene names: 126447774

Gene position: 436798-438474 (Clockwise)

Preceding gene: 126447357

Following gene: 126447152

Centisome position: 18.57

GC content: 64.04

Gene sequence:

>1677_bases
TTGACGCTTGCCATGACGGTGTTGCTGGCGGGCCGCTCGGCGCCGGCAAGCGCGTTCGGGCCGACGGTGCAGGACCGGGA
GCGGGATCTGGGGGAGAAGGCGCGACGGCAGCAGATGATCGAACAGCATAGGCGGGGGCATGCGGCCGAGCCGGCGGCCG
GGTTGCCGGCGCCAGTGCAAGCACCCGAGTTGGGCGGTGCGCGTTTCCCGATCACGCAAATCGAAGTGCGGGGCGGGGCG
CGCCATAGCCGGGAGATCGACCGGATTGTCGAGCGCTACCGGGGCGCGACCATGGGGCAGGCGGAGATTTTCGCGCTGTT
GCGTGATCTGATGAATTTCTACTATGGCCGCGGTTATATCACGACCGGCGTGTCGCTCGCCGAGCAAAACCTGTCGAGCG
GGAAGCTGATCGTGGTGGTCCATTGGGGCTACGTGAAGGGATGGCGCGTGAACGGCAAGGCGCCGGAGGGCATGCGCGAG
CGGTTGATGTTGAGCAGCGCGATGCCTGGCATAGAAGGTTCCGTTTTGAACATCCACGATATCGACCAGGCGATCGAGAA
TCTGAACGGCTTGGGCAGAGCCGCCAAGATCAACGTCGTCCCCGCCGAGGAAGCCGGGTATTCCTATCTGGACGTCGTTT
TGCAACGCTCGAAGCCGTTCGCGGTGTCGGCGTCGGTCGATAACTCGGGTCTCGGCGATCGAGCGGGCGACGGCTTATAC
CGGTATGGCGTCGATATCGCGGTGGCGCACCTGCTGGGCTGGAACGACGTGCTGACGCTCTCGGCCGGCCGTCGCTACTA
CCAGGACCCCGCCCATCATGCCTACGATTCGCTGGCCGTGTCATACGGATGGCGCGTGGGCCGCTGGAGCGCCGATCTGC
GGTATATCGCGCAGCCGACCAAGAGCCTCCTTTCCGGAACCTATGGTGACTACCAACTGAGCGGCAATACGCAGGATGTC
AACCTGCGCGTGTCGCGCGTGCTTCGGCGCTGGCGGACCGGCACGGATGCCGTCTACGTTGCGATCGACCGCAAGCGCGT
GCGCAACTATATCGACGACACGCTGATCGAGATCAACAGCAACACCCATACGAGCGTCACGGCGGGAGTCAATCGGCTGG
ACAGTCTGTTCGGCGGAGTCGTATTCGCGGATGGGGGCTGGACGAGGGGCGTGGGCTGGCTGGGGGCGAGCGAGGACCCT
GTGTCCGCCGGGCAAGGGCCGCTGTCGCGTTACGACAAATTCAATCTGAACCTGAACTGGTCGCGCGACTTCACGGCGGG
CTCGTTGCGAGCCCGTTACACGGCGGCGATGGGGGCGCAGTATTCGAAGGATGACCTGTACTACGACAGCAAGTTCGTCA
TTGGCGACCAGTACACGGTGCGCGGCTTCAAGATCCGGTCTGCCTATGGGGATAGCGGCGTGTCTGTATCGAACACGCTG
AGCTTTCCGTTTCCGACGTCGATCGGAACGGTCACACCGTTGGTCGGTGTGGATTGGGGTGCCGTCGGGAACAACGGCGA
AGCGGACAATGGCGGCTGGATCGGCGCAGTTGCGGGCGGGCTCCGGGTGTCGACGAAATGGGCCAATGCGGCGGTGACCA
TCGGCAAGCCGTTCAGGGCGCTGCCGGGCATGGGGTACGGGGTGGTCTGGTATTTGAGCGCATCAGCCACGTATTAG

Upstream 100 bases:

>100_bases
ATCGGATGCCGGCGTTGGCAAGGGCATTCGATCGGCGCGAGCGGTCAGTCGGGAAGAGCGGGCGCACGGGGCGTACGGGC
GCGTGTTGACGCATATCGTT

Downstream 100 bases:

>100_bases
CCACGGGCCGTGCGCATACGAACCGGCGGTCGTTTCGCCGAGCGTTGAATCGATACATGGCATGGAATGCCAATGATCAG
TCATGCAGAGGAATGAGGTC

Product: HlyB family hemolysin activator protein

Products: NA

Alternate protein names: TpsB transporter [H]

Number of amino acids: Translated: 558; Mature: 557

Protein sequence:

>558_residues
MTLAMTVLLAGRSAPASAFGPTVQDRERDLGEKARRQQMIEQHRRGHAAEPAAGLPAPVQAPELGGARFPITQIEVRGGA
RHSREIDRIVERYRGATMGQAEIFALLRDLMNFYYGRGYITTGVSLAEQNLSSGKLIVVVHWGYVKGWRVNGKAPEGMRE
RLMLSSAMPGIEGSVLNIHDIDQAIENLNGLGRAAKINVVPAEEAGYSYLDVVLQRSKPFAVSASVDNSGLGDRAGDGLY
RYGVDIAVAHLLGWNDVLTLSAGRRYYQDPAHHAYDSLAVSYGWRVGRWSADLRYIAQPTKSLLSGTYGDYQLSGNTQDV
NLRVSRVLRRWRTGTDAVYVAIDRKRVRNYIDDTLIEINSNTHTSVTAGVNRLDSLFGGVVFADGGWTRGVGWLGASEDP
VSAGQGPLSRYDKFNLNLNWSRDFTAGSLRARYTAAMGAQYSKDDLYYDSKFVIGDQYTVRGFKIRSAYGDSGVSVSNTL
SFPFPTSIGTVTPLVGVDWGAVGNNGEADNGGWIGAVAGGLRVSTKWANAAVTIGKPFRALPGMGYGVVWYLSASATY

Sequences:

>Translated_558_residues
MTLAMTVLLAGRSAPASAFGPTVQDRERDLGEKARRQQMIEQHRRGHAAEPAAGLPAPVQAPELGGARFPITQIEVRGGA
RHSREIDRIVERYRGATMGQAEIFALLRDLMNFYYGRGYITTGVSLAEQNLSSGKLIVVVHWGYVKGWRVNGKAPEGMRE
RLMLSSAMPGIEGSVLNIHDIDQAIENLNGLGRAAKINVVPAEEAGYSYLDVVLQRSKPFAVSASVDNSGLGDRAGDGLY
RYGVDIAVAHLLGWNDVLTLSAGRRYYQDPAHHAYDSLAVSYGWRVGRWSADLRYIAQPTKSLLSGTYGDYQLSGNTQDV
NLRVSRVLRRWRTGTDAVYVAIDRKRVRNYIDDTLIEINSNTHTSVTAGVNRLDSLFGGVVFADGGWTRGVGWLGASEDP
VSAGQGPLSRYDKFNLNLNWSRDFTAGSLRARYTAAMGAQYSKDDLYYDSKFVIGDQYTVRGFKIRSAYGDSGVSVSNTL
SFPFPTSIGTVTPLVGVDWGAVGNNGEADNGGWIGAVAGGLRVSTKWANAAVTIGKPFRALPGMGYGVVWYLSASATY
>Mature_557_residues
TLAMTVLLAGRSAPASAFGPTVQDRERDLGEKARRQQMIEQHRRGHAAEPAAGLPAPVQAPELGGARFPITQIEVRGGAR
HSREIDRIVERYRGATMGQAEIFALLRDLMNFYYGRGYITTGVSLAEQNLSSGKLIVVVHWGYVKGWRVNGKAPEGMRER
LMLSSAMPGIEGSVLNIHDIDQAIENLNGLGRAAKINVVPAEEAGYSYLDVVLQRSKPFAVSASVDNSGLGDRAGDGLYR
YGVDIAVAHLLGWNDVLTLSAGRRYYQDPAHHAYDSLAVSYGWRVGRWSADLRYIAQPTKSLLSGTYGDYQLSGNTQDVN
LRVSRVLRRWRTGTDAVYVAIDRKRVRNYIDDTLIEINSNTHTSVTAGVNRLDSLFGGVVFADGGWTRGVGWLGASEDPV
SAGQGPLSRYDKFNLNLNWSRDFTAGSLRARYTAAMGAQYSKDDLYYDSKFVIGDQYTVRGFKIRSAYGDSGVSVSNTLS
FPFPTSIGTVTPLVGVDWGAVGNNGEADNGGWIGAVAGGLRVSTKWANAAVTIGKPFRALPGMGYGVVWYLSASATY

Specific function: Member of a two partner secretion pathway (TPS) in which it mediates the secretion of filamentous hemagglutinin (FHA) [H]

COG id: COG2831

COG function: function code U; Hemolysin activation/secretion protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tpsB (TC 1.B.20) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005565
- InterPro:   IPR013686 [H]

Pfam domain/function: PF08479 POTRA_2; PF03865 ShlB [H]

EC number: NA

Molecular weight: Translated: 60616; Mature: 60485

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLAMTVLLAGRSAPASAFGPTVQDRERDLGEKARRQQMIEQHRRGHAAEPAAGLPAPVQ
CCEEEEEEEECCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
APELGGARFPITQIEVRGGARHSREIDRIVERYRGATMGQAEIFALLRDLMNFYYGRGYI
CCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEE
TTGVSLAEQNLSSGKLIVVVHWGYVKGWRVNGKAPEGMRERLMLSSAMPGIEGSVLNIHD
ECCHHHHHCCCCCCCEEEEEEECCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCEEEHHH
IDQAIENLNGLGRAAKINVVPAEEAGYSYLDVVLQRSKPFAVSASVDNSGLGDRAGDGLY
HHHHHHHHHCCCCEEEEEEEECHHCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHH
RYGVDIAVAHLLGWNDVLTLSAGRRYYQDPAHHAYDSLAVSYGWRVGRWSADLRYIAQPT
HHHHHHHHHHHHCCCCEEEECCCCHHHCCCHHHHHHHHHHHCCCEEECCCCCHHHHHHHH
KSLLSGTYGDYQLSGNTQDVNLRVSRVLRRWRTGTDAVYVAIDRKRVRNYIDDTLIEINS
HHHHCCCCCCEEECCCCCEEEHHHHHHHHHHCCCCCEEEEEECHHHHHHHHCCEEEEECC
NTHTSVTAGVNRLDSLFGGVVFADGGWTRGVGWLGASEDPVSAGQGPLSRYDKFNLNLNW
CCCCCHHHHHHHHHHHHCCEEEECCCCCCCEECCCCCCCCCCCCCCCHHHCCEEEEEEEC
SRDFTAGSLRARYTAAMGAQYSKDDLYYDSKFVIGDQYTVRGFKIRSAYGDSGVSVSNTL
CCCCCCCCHHHHHHHHHCCCCCCCCCEECCEEEECCCEEEEEEEEEECCCCCCCEECCEE
SFPFPTSIGTVTPLVGVDWGAVGNNGEADNGGWIGAVAGGLRVSTKWANAAVTIGKPFRA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEEECCEEEEECCCHHH
LPGMGYGVVWYLSASATY
CCCCCCEEEEEEECCCCC
>Mature Secondary Structure 
TLAMTVLLAGRSAPASAFGPTVQDRERDLGEKARRQQMIEQHRRGHAAEPAAGLPAPVQ
CEEEEEEEECCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
APELGGARFPITQIEVRGGARHSREIDRIVERYRGATMGQAEIFALLRDLMNFYYGRGYI
CCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEE
TTGVSLAEQNLSSGKLIVVVHWGYVKGWRVNGKAPEGMRERLMLSSAMPGIEGSVLNIHD
ECCHHHHHCCCCCCCEEEEEEECCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCEEEHHH
IDQAIENLNGLGRAAKINVVPAEEAGYSYLDVVLQRSKPFAVSASVDNSGLGDRAGDGLY
HHHHHHHHHCCCCEEEEEEEECHHCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHH
RYGVDIAVAHLLGWNDVLTLSAGRRYYQDPAHHAYDSLAVSYGWRVGRWSADLRYIAQPT
HHHHHHHHHHHHCCCCEEEECCCCHHHCCCHHHHHHHHHHHCCCEEECCCCCHHHHHHHH
KSLLSGTYGDYQLSGNTQDVNLRVSRVLRRWRTGTDAVYVAIDRKRVRNYIDDTLIEINS
HHHHCCCCCCEEECCCCCEEEHHHHHHHHHHCCCCCEEEEEECHHHHHHHHCCEEEEECC
NTHTSVTAGVNRLDSLFGGVVFADGGWTRGVGWLGASEDPVSAGQGPLSRYDKFNLNLNW
CCCCCHHHHHHHHHHHHCCEEEECCCCCCCEECCCCCCCCCCCCCCCHHHCCEEEEEEEC
SRDFTAGSLRARYTAAMGAQYSKDDLYYDSKFVIGDQYTVRGFKIRSAYGDSGVSVSNTL
CCCCCCCCHHHHHHHHHCCCCCCCCCEECCEEEECCCEEEEEEEEEECCCCCCCEECCEE
SFPFPTSIGTVTPLVGVDWGAVGNNGEADNGGWIGAVAGGLRVSTKWANAAVTIGKPFRA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEEECCEEEEECCCHHH
LPGMGYGVVWYLSASATY
CCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]